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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Circadian control of innate immunity in macrophages by miR-155 targeting Bmal1

Authors:
Curtis AM, Fagundes CT, Yang G, Palsson-McDermott EM, Wochal P, McGettrick AF, Foley NH, Early JO, Chen L, Zhang H, Xue C, Geiger SS, Hokamp K, Reilly MP, Coogan AN, Vigorito E, FitzGerald GA, O'Neill LA
Citation:
Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):7231-6. doi: 10.1073/pnas.1501327112. Epub 2015 May 20.
Epub:
Yes
Abstract:
The response to an innate immune challenge is conditioned by the time of day, but the molecular basis for this remains unclear...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: bone-marrow-derived macrophage (BMDM)
Citation Extract:
Curtis AM, Fagundes CT, Yang G, Palsson-McDermott EM, Wochal P, McGettrick AF, Foley NH, Early JO, Chen L, Zhang H, Xue C, Geiger SS, Hokamp K, Reilly MP, Coogan AN, Vigorito E, FitzGerald GA, O'Neill LA. Circadian control of innate immunity in macrophages by miR-155 targeting Bmal1. Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):7231-6. doi: 10.1073/pnas.1501327112. Epub 2015 May 20..

Neuregulin 1 Type II-ErbB Signaling Promotes Cell Divisions Generating Neurons from Neural Progenitor Cells in the Developing Zebrafish Brain

Authors:
Sato T, Sato F, Kamezaki A, Sakaguchi K, Tanigome R, Kawakami K, Sehara-Fujisawa A
Citation:
PLoS One. 2015 May 22;10(5):e0127360. doi: 10.1371/journal.pone.0127360. eCollection 2015
Epub:
Not Epub
Abstract:
Post-mitotic neurons are generated from neural progenitor cells (NPCs) at the expense of their proliferation. Molecular and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sato T, Sato F, Kamezaki A, Sakaguchi K, Tanigome R, Kawakami K, Sehara-Fujisawa A. Neuregulin 1 Type II-ErbB Signaling Promotes Cell Divisions Generating Neurons from Neural Progenitor Cells in the Developing Zebrafish Brain. PLoS One. 2015 May 22;10(5):e0127360. doi: 10.1371/journal.pone.0127360. eCollection 2015.

Heme-mediated inhibition of Bach1 regulates the liver specificity and transience of the Nrf2-dependent induction of zebrafish heme oxygenase 1

Authors:
Fuse Y, Nakajima H, Nakajima-Takagi Y, Nakajima O, Kobayashi M
Citation:
Genes Cells. 2015 May 18. doi: 10.1111/gtc.12249. [Epub ahead of print]
Epub:
Yes
Abstract:
The induction of the gene encoding heme oxygenase 1 (Hmox1, HO-1) by Nrf2 is unique compared with other Nrf2 targets. We...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fuse Y, Nakajima H, Nakajima-Takagi Y, Nakajima O, Kobayashi M. Heme-mediated inhibition of Bach1 regulates the liver specificity and transience of the Nrf2-dependent induction of zebrafish heme oxygenase 1. Genes Cells. 2015 May 18. doi: 10.1111/gtc.12249. [Epub ahead of print].

Ribonuclease like 5 regulates zebrafish yolk extension by suppressing a p53-dependent DNA damage response pathway

Authors:
Zhai Y, Zhao X, Sheng J, Gao X, Ou Z, Xu Z
Citation:
Int J Biochem Cell Biol. 2015 May 14. pii: S1357-2725(15)00125-9. doi: 10.1016/j.biocel.2015.05.004. [Epub ahead of print]
Epub:
Yes
Abstract:
Ribonuclease like 5 (Rnasel5) is a novel member of the zebrafish ribonuclease A family and its expression is increased during...
Organism or Cell Type:
zebrafish
Citation Extract:
Zhai Y, Zhao X, Sheng J, Gao X, Ou Z, Xu Z. Ribonuclease like 5 regulates zebrafish yolk extension by suppressing a p53-dependent DNA damage response pathway. Int J Biochem Cell Biol. 2015 May 14. pii: S1357-2725(15)00125-9. doi: 10.1016/j.biocel.2015.05.004. [Epub ahead of print].

Inactivating mutations in MFSD2A, required for omega-3 fatty acid transport in brain, cause a lethal microcephaly syndrome

Authors:
Guemez-Gamboa A, Nguyen LN, Yang H, Zaki MS, Kara M, Ben-Omran T, Akizu N, Rosti RO, Rosti B, Scott E, Schroth J, Copeland B, Vaux KK, Cazenave-Gassiot A, Quek DQ, Wong BH, Tan BC, Wenk MR, Gunel M, Gabriel S, Chi NC, Silver DL, Gleeson JG
Citation:
Nat Genet. 2015 May 25. doi: 10.1038/ng.3311. [Epub ahead of print]
Epub:
Yes
Abstract:
Docosahexanoic acid (DHA) is the most abundant omega-3 fatty acid in brain, and, although it is considered essential,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Guemez-Gamboa A, Nguyen LN, Yang H, Zaki MS, Kara M, Ben-Omran T, Akizu N, Rosti RO, Rosti B, Scott E, Schroth J, Copeland B, Vaux KK, Cazenave-Gassiot A, Quek DQ, Wong BH, Tan BC, Wenk MR, Gunel M, Gabriel S, Chi NC, Silver DL, Gleeson JG. Inactivating mutations in MFSD2A, required for omega-3 fatty acid transport in brain, cause a lethal microcephaly syndrome. Nat Genet. 2015 May 25. doi: 10.1038/ng.3311. [Epub ahead of print].

Induction of Phosphoenolpyruvate Carboxykinase (PEPCK) during Acute Acidosis and Its Role in Acid Secretion by V-ATPase-Expressing Ionocytes

Authors:
Furukawa F, Tseng YC, Liu ST, Chou YL, Lin CC, Sung PH, Uchida K, Lin LY, Hwang PP
Citation:
Int J Biol Sci. 2015 May 1;11(6):712-725. eCollection 2015
Epub:
Not Epub
Abstract:
Vacuolar-Type H+-ATPase (V-ATPase) takes the central role in pumping H+ through cell membranes of diverse organisms, which is...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Furukawa F, Tseng YC, Liu ST, Chou YL, Lin CC, Sung PH, Uchida K, Lin LY, Hwang PP. Induction of Phosphoenolpyruvate Carboxykinase (PEPCK) during Acute Acidosis and Its Role in Acid Secretion by V-ATPase-Expressing Ionocytes. Int J Biol Sci. 2015 May 1;11(6):712-725. eCollection 2015.

Functional analysis of hairy genes in Xenopus neural crest initial specification and cell migration

Authors:
Vega-López GA, Bonano M, Tríbulo C, Fernández JP, Agüero TH, Aybar MJ
Citation:
Dev Dyn. 2015 May 22. doi: 10.1002/dvdy.24295. [Epub ahead of print]
Epub:
Yes
Abstract:
BACKGROUND: Neural crest formation is one of the fundamental processes in the early stages of embryonic development in...
Organism or Cell Type:
Xenopus
Citation Extract:
Vega-López GA, Bonano M, Tríbulo C, Fernández JP, Agüero TH, Aybar MJ. Functional analysis of hairy genes in Xenopus neural crest initial specification and cell migration. Dev Dyn. 2015 May 22. doi: 10.1002/dvdy.24295. [Epub ahead of print].

Proper Activity of Histone H3 Lysine 4 (H3K4) Methyltransferase Is Required for Morphogenesis during Zebrafish Cardiogenesis

Authors:
Kim JD, Kim E, Koun S, Ham HJ, Rhee M, Kim MJ, Huh TL
Citation:
Mol Cells. 2015 May 22. doi: 10.14348/molcells.2015.0053. [Epub ahead of print]
Epub:
Yes
Abstract:
While increasing evidence indicate the important function of histone methylation during development, how this process influence...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim JD, Kim E, Koun S, Ham HJ, Rhee M, Kim MJ, Huh TL. Proper Activity of Histone H3 Lysine 4 (H3K4) Methyltransferase Is Required for Morphogenesis during Zebrafish Cardiogenesis. Mol Cells. 2015 May 22. doi: 10.14348/molcells.2015.0053. [Epub ahead of print].

Differing roles of pyruvate dehydrogenase kinases during mouse oocyte maturation

Authors:
Hou X, Zhang L, Han L, Ge J, Ma R, Zhang X, Moley K, Schedl T, Wang Q
Citation:
J Cell Sci. 2015;128:2319-29. doi:10.1242/​jcs.167049
Epub:
Not Epub
Abstract:
Pyruvate dehydrogenase kinases (PDKs) modulate energy homeostasis in multiple tissues/cell types, under various nutrient...
Organism or Cell Type:
mouse oocyte
Citation Extract:
Hou X, Zhang L, Han L, Ge J, Ma R, Zhang X, Moley K, Schedl T, Wang Q. Differing roles of pyruvate dehydrogenase kinases during mouse oocyte maturation. J Cell Sci. 2015;128:2319-29. doi:10.1242/​jcs.167049.

Nitric Oxide Synthase Inhibition Modulates Immune Polarization and Improves Radiation-Induced Tumor Growth Delay

Authors:
Ridnour LA, Cheng RY, Weiss JM, Soto-Pantoja DR, Basudhar D, Heinecke JL, Stewart A, DeGraff WG, Sowers A, Thetford A, Kesarwala AH, Roberts DD, Young HA, Mitchell JB, Trinchieri G, Wiltrout RH, Wink DA
Citation:
Cancer Res. 2015 Jul 15;75(14):2788-99. doi: 10.1158/0008-5472.CAN-14-3011. Epub 2015 May 19.
Epub:
Yes
Abstract:
Nitric oxide synthases (NOS) are important mediators of pro-growth signaling in tumor cells, as they regulate angiogenesis,...
Delivery Method:
injection (mice)
Organism or Cell Type:
cell culture: Raw 267.4, mouse
Citation Extract:
Ridnour LA, Cheng RY, Weiss JM, Soto-Pantoja DR, Basudhar D, Heinecke JL, Stewart A, DeGraff WG, Sowers A, Thetford A, Kesarwala AH, Roberts DD, Young HA, Mitchell JB, Trinchieri G, Wiltrout RH, Wink DA. Nitric Oxide Synthase Inhibition Modulates Immune Polarization and Improves Radiation-Induced Tumor Growth Delay. Cancer Res. 2015 Jul 15;75(14):2788-99. doi: 10.1158/0008-5472.CAN-14-3011. Epub 2015 May 19..

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