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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Cdc42 and sec10 Are Required for Normal Retinal Development in Zebrafish

Authors:
Choi SY, Baek J-I, Zuo X, Kim S-H, Dunaief JL, Lipschutz JH
Citation:
IOVS. 2015;56:3361-70. doi:10.1167/iovs.14-15692
Epub:
Not Epub
Abstract:
Purpose. To characterize the function and mechanisms of cdc42 and sec10 in eye development in zebrafish. Methods. Knockdown of...
Link:
http://iovs.arvojournals.org/Article.aspx?articleid=2299622
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Choi SY, Baek J-I, Zuo X, Kim S-H, Dunaief JL, Lipschutz JH. Cdc42 and sec10 Are Required for Normal Retinal Development in Zebrafish. IOVS. 2015;56:3361-70. doi:10.1167/iovs.14-15692.

The hormonal peptide Elabela guides angioblasts to the midline during vasculogenesis

Authors:
Helker CSM, Schuermann A, Pollmann C, Chng SC, Kiefer F, Reversade B, Herzog W
Citation:
eLife 2015;10.7554/eLife.06726
Epub:
Not Epub
Abstract:
A key step in the de novo formation of the embryonic vasculature is the migration of endothelial precursors, the angioblasts,...
Link:
http://elifesciences.org/content/early/2015/05/27/eLife.06726
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Helker CSM, Schuermann A, Pollmann C, Chng SC, Kiefer F, Reversade B, Herzog W. The hormonal peptide Elabela guides angioblasts to the midline during vasculogenesis. eLife 2015;10.7554/eLife.06726.

Abnormal splicing switch of DMD’s penultimate exon compromises muscle fibre maintenance in myotonic dystrophy

Authors:
Rau F, Lainé J, Ramanoudjame L, Ferry A, Arandel L, Delalande O, Jollet A, Dingli F, Lee K-Y, Peccate C, Lorain S, Kabashi E, Athanasopoulos T, Koo T, Loew D, Swanson MS, Le Rumeur E, Dickson G, Allamand V, Marie J, Furling D
Citation:
Nat Comm. 2015;6:7205. doi:10.1038/ncomms8205
Epub:
Not Epub
Abstract:
Myotonic Dystrophy type 1 (DM1) is a dominant neuromuscular disease caused by nuclear-retained RNAs containing expanded CUG...
Link:
http://www.nature.com/ncomms/2015/150528/ncomms8205/full/ncomms8205.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rau F, Lainé J, Ramanoudjame L, Ferry A, Arandel L, Delalande O, Jollet A, Dingli F, Lee K-Y, Peccate C, Lorain S, Kabashi E, Athanasopoulos T, Koo T, Loew D, Swanson MS, Le Rumeur E, Dickson G, Allamand V, Marie J, Furling D. Abnormal splicing switch of DMD’s penultimate exon compromises muscle fibre maintenance in myotonic dystrophy. Nat Comm. 2015;6:7205. doi:10.1038/ncomms8205.

Analysis of the nicotinamide phosphoribosyltransferase (NAMPT) family provides insight into vertebrate adaptation to different oxygen levels during the water-to-land transition

Authors:
Fang C, Guan L, Zhong Z, Gan X, He S
Citation:
FEBS J. 2015 May 25. doi: 10.1111/febs.13327. [Epub ahead of print]
Epub:
Yes
Abstract:
One of the most important events in vertebrate evolutionary history is the water-to-land transition, during which some...
Link:
http://onlinelibrary.wiley.com/doi/10.1111/febs.13327/abstract
Citation Extract:
Fang C, Guan L, Zhong Z, Gan X, He S. Analysis of the nicotinamide phosphoribosyltransferase (NAMPT) family provides insight into vertebrate adaptation to different oxygen levels during the water-to-land transition. FEBS J. 2015 May 25. doi: 10.1111/febs.13327. [Epub ahead of print].

Centrin-2 (Cetn2) mediated regulation of FGF/FGFR gene expression in Xenopus

Authors:
Shi J, Zhao Y, Vonderfecht T, Winey M, Klymkowsky MW
Citation:
Sci Rep. 2015;5:10283. doi:10.1038/srep10283
Epub:
Not Epub
Abstract:
Centrins (Cetns) are highly conserved, widely expressed, and multifunctional Ca2+-binding eukaryotic signature proteins best...
Link:
http://www.nature.com/srep/2015/150527/srep10283/full/srep10283.html
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Shi J, Zhao Y, Vonderfecht T, Winey M, Klymkowsky MW. Centrin-2 (Cetn2) mediated regulation of FGF/FGFR gene expression in Xenopus. Sci Rep. 2015;5:10283. doi:10.1038/srep10283.

Polo-like kinase 2 regulates angiogenic sprouting and blood vessel development

Authors:
Yang H, Fang L, Zhan R, Hegarty JM, Ren J, Hsiai TK, Gleeson JG, Miller YI, Trejo J, Chi NC
Citation:
Dev Biol. 2015 May 21. pii: S0012-1606(15)00280-8. doi: 10.1016/j.ydbio.2015.05.011. [Epub ahead of print]
Epub:
Yes
Abstract:
Angiogenesis relies on specialized endothelial tip cells to extend toward guidance cues in order to direct growing blood...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160615002808
Organism or Cell Type:
zebrafish
Citation Extract:
Yang H, Fang L, Zhan R, Hegarty JM, Ren J, Hsiai TK, Gleeson JG, Miller YI, Trejo J, Chi NC. Polo-like kinase 2 regulates angiogenic sprouting and blood vessel development. Dev Biol. 2015 May 21. pii: S0012-1606(15)00280-8. doi: 10.1016/j.ydbio.2015.05.011. [Epub ahead of print].

Paraxis is required for somite morphogenesis and differentiation in Xenopus laevis

Authors:
Sánchez RS, Sánchez SS
Citation:
Dev Dyn. 2015 May 22. doi: 10.1002/dvdy.24294. [Epub ahead of print]
Epub:
Yes
Abstract:
BACKGROUND: In most vertebrates the segmentation of the paraxial mesoderm involves the formation of metameric units called...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/dvdy.24294/abstract
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Sánchez RS, Sánchez SS. Paraxis is required for somite morphogenesis and differentiation in Xenopus laevis. Dev Dyn. 2015 May 22. doi: 10.1002/dvdy.24294. [Epub ahead of print].

E2F8 promotes hepatic steatosis through FABP3 expression in diet-induced obesity in zebrafish

Authors:
Shimada Y, Kuninaga S, Ariyoshi M, Zhang B, Shiina Y, Takahashi Y, Umemoto N, Nishimura Y, Enari H, Tanaka T
Citation:
Nutrition & Metabolism. 2015;12(1). doi:10.1186/s12986-015-0012-7
Epub:
Not Epub
Abstract:
Background Diet-induced hepatic steatosis is highly associated with nonalcoholic fatty liver disease, which is related to the...
Link:
http://www.nutritionandmetabolism.com/content/12/1/17/abstract
Delivery Method:
injection (i.p.) with Lipofectamine 2000
Organism or Cell Type:
zebrafish
Citation Extract:
Shimada Y, Kuninaga S, Ariyoshi M, Zhang B, Shiina Y, Takahashi Y, Umemoto N, Nishimura Y, Enari H, Tanaka T. E2F8 promotes hepatic steatosis through FABP3 expression in diet-induced obesity in zebrafish. Nutrition & Metabolism. 2015;12(1). doi:10.1186/s12986-015-0012-7.

Lymphatic vessels arise from specialized angioblasts within a venous niche

Authors:
Nicenboim J, Malkinson G, Lupo T, Asaf L, Sela Y, Mayseless O, Gibbs-Bar L, Senderovich N, Hashimshony T, Shin M, Jerafi-Vider A, Avraham-Davidi I, Krupalnik V, Hofi R, Almog G, Astin JW, Golani O, Ben-Dor S, Crosier PS, Herzog W, Lawson ND, Hanna JH, Yanai I, Yaniv K
Citation:
Nature. 2015 May 20. doi: 10.1038/nature14425. [Epub ahead of print]
Epub:
Yes
Abstract:
How cells acquire their fate is a fundamental question in developmental and regenerative biology. Multipotent progenitors...
Link:
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature14425.html
Organism or Cell Type:
zebrafish
Citation Extract:
Nicenboim J, Malkinson G, Lupo T, Asaf L, Sela Y, Mayseless O, Gibbs-Bar L, Senderovich N, Hashimshony T, Shin M, Jerafi-Vider A, Avraham-Davidi I, Krupalnik V, Hofi R, Almog G, Astin JW, Golani O, Ben-Dor S, Crosier PS, Herzog W, Lawson ND, Hanna JH, Yanai I, Yaniv K. Lymphatic vessels arise from specialized angioblasts within a venous niche. Nature. 2015 May 20. doi: 10.1038/nature14425. [Epub ahead of print].

Transcriptional regulator PRDM12 is essential for human pain perception

Authors:
Chen YC, Auer-Grumbach M, Matsukawa S, Zitzelsberger M, Themistocleous AC, Strom TM, Samara C, Moore AW, Cho LT, Young GT, Weiss C, Schabhüttl M, Stucka R, Schmid AB, Parman Y, Graul-Neumann L, Heinritz W, Passarge E, Watson RM, Hertz JM, Moog U, Baumgartner M, Valente EM, Pereira D, Restrepo CM, Katona I, Dusl M, Stendel C, Wieland T, Stafford F, Reimann F, von Au K, Finke C, Willems PJ, Nahorski MS, Shaikh SS, Carvalho OP, Nicholas AK, Karbani G, McAleer MA, Cilio MR, McHugh JC, Murphy SM, Irvine AD, Jensen UB, Windhager R, Weis J, Bergmann C, Rautenstrauss B, Baets J, De Jonghe P, Reilly MM, Kropatsch R, Kurth I, Chrast R, Michiue T, Bennett DL, Woods CG, Senderek J
Citation:
Nat Genet. 2015 May 25. doi: 10.1038/ng.3308. [Epub ahead of print]
Epub:
Yes
Abstract:
Pain perception has evolved as a warning mechanism to alert organisms to tissue damage and dangerous environments. In humans,...
Link:
http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3308.html
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Chen YC, Auer-Grumbach M, Matsukawa S, Zitzelsberger M, Themistocleous AC, Strom TM, Samara C, Moore AW, Cho LT, Young GT, Weiss C, Schabhüttl M, Stucka R, Schmid AB, Parman Y, Graul-Neumann L, Heinritz W, Passarge E, Watson RM, Hertz JM, Moog U, Baumgartner M, Valente EM, Pereira D, Restrepo CM, Katona I, Dusl M, Stendel C, Wieland T, Stafford F, Reimann F, von Au K, Finke C, Willems PJ, Nahorski MS, Shaikh SS, Carvalho OP, Nicholas AK, Karbani G, McAleer MA, Cilio MR, McHugh JC, Murphy SM, Irvine AD, Jensen UB, Windhager R, Weis J, Bergmann C, Rautenstrauss B, Baets J, De Jonghe P, Reilly MM, Kropatsch R, Kurth I, Chrast R, Michiue T, Bennett DL, Woods CG, Senderek J. Transcriptional regulator PRDM12 is essential for human pain perception. Nat Genet. 2015 May 25. doi: 10.1038/ng.3308. [Epub ahead of print].

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