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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
PIAS-like protein Zimp7 is required for the restriction of the Zebrafish organizer and mesoderm development
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Citation:
Dev Biol. 2015 Apr 23. pii: S0012-1606(15)00213-4. doi: 10.1016/j.ydbio.2015.04.013. [Epub ahead of print] Epub:
Not Epub Abstract:
The Zmiz2 (Zimp7) protein and its homolog Zmiz1 (Zimp10) were initially identified in humans as androgen receptor co-activators... Organism or Cell Type:
zebrafish Citation Extract: Moreno-Ayala R, Schnabel D, Salas-Vidal E, Lomelí H. PIAS-like protein Zimp7 is required for the restriction of the Zebrafish organizer and mesoderm development. Dev Biol. 2015 Apr 23. pii: S0012-1606(15)00213-4. doi: 10.1016/j.ydbio.2015.04.013. [Epub ahead of print]. |
Eteplirsen, a Phosphorodiamidate Morpholino Oligomer (PMO) for the Treatment of Duchenne Muscular Dystrophy (DMD): 168 Week Update on Six-Minute Walk Test (6MWT), Pulmonary Function Testing (PFT), and Safety
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Citation:
European Journal of Paediatric Neurology. 2015;V19(Supp 1):S69 Epub:
Not Epub Abstract:
Background/Objective: DMD is a rare, degenerative, X-linked recessive genetic disease that results in progressive muscle loss... Delivery Method:
intravenous infusion Organism or Cell Type:
human Citation Extract: Mendell JR, Rodino-Klapac L, Sahenk Z, Rouch K, Bird L, Lowes L, Alfano L, Berry K, Lewis S, Shontz K, Flanigan K, Shilling C, Duda P, Saoud J. Eteplirsen, a Phosphorodiamidate Morpholino Oligomer (PMO) for the Treatment of Duchenne Muscular Dystrophy (DMD): 168 Week Update on Six-Minute Walk Test (6MWT), Pulmonary Function Testing (PFT), and Safety. European Journal of Paediatric Neurology. 2015;V19(Supp 1):S69. |
Tight junction protein 1a regulates pigment cell organisation during zebrafish colour patterning
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Citation:
eLife. 2015;10.7554/eLife.06545. doi:10.7554/eLife.06545 Epub:
Not Epub Abstract:
Zebrafish display a prominent pattern of alternating dark and light stripes generated by the precise positioning of pigment... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fadeev A, Krauss J, Frohnhöfer HG, Irion U, Nüsslein-Volhard C. Tight junction protein 1a regulates pigment cell organisation during zebrafish colour patterning. eLife. 2015;10.7554/eLife.06545. doi:10.7554/eLife.06545. |
Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis
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Citation:
J Clin Invest. 2015;[Epub ahead of print] doi:10.1172/JCI75836 Epub:
Yes Abstract:
Glutaminase (GLS), which converts glutamine to glutamate, plays a key role in cancer cell metabolism, growth, and proliferation... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: P493 cells; mouse xenograft p493 tumors Citation Extract: Xiang Y, Stine ZE, Xia J, Lu Y, O’Connor RS, Altman BJ, Hsieh AL, Gouw AM, Thomas AG, Gao P, Sun L, Song L, Yan B, Slusher BS, Zhuo J, Ooi LL, Lee CGL, Mancuso A, McCallion AS, Le A, Milone MC, Rayport S, Felsher DW, Dang CV. Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis. J Clin Invest. 2015;[Epub ahead of print] doi:10.1172/JCI75836. |
Myosin light chain kinase regulates cell polarization independently of membrane tension or Rho kinase
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Citation:
J Cell Biol. 2015;209:275-88. doi:10.1083/jcb.201409001 Epub:
Not Epub Abstract:
Cells polarize to a single front and rear to achieve rapid actin-based motility, but the mechanisms preventing the formation of... Organism or Cell Type:
zebrafish keratocytes Citation Extract: Lou SS, Diz-Muñoz A, Weiner OD, Fletcher DA, Theriot JA. Myosin light chain kinase regulates cell polarization independently of membrane tension or Rho kinase. J Cell Biol. 2015;209:275-88. doi:10.1083/jcb.201409001. |
A Two-Step Pretargeted Nanotherapy for CD20 Crosslinking May Achieve Superior Anti-Lymphoma Efficacy to Rituximab
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Citation:
Theranostics. 2015;5(8):834-46. doi:10.7150/thno.12040 Epub:
Not Epub Abstract:
The use of rituximab, an anti-CD20 mAb, in combination with chemotherapy is the current standard for the treatment of B-cell... Delivery Method:
culture: cell bathing, mouse: injection Organism or Cell Type:
cell culture: patient mantle cell lymphoma Citation Extract: Chu TW, Zhang R, Yang J, Chao MP, Shami PJ, Kopeček J. A Two-Step Pretargeted Nanotherapy for CD20 Crosslinking May Achieve Superior Anti-Lymphoma Efficacy to Rituximab. Theranostics. 2015;5(8):834-46. doi:10.7150/thno.12040. |
Dystrophic muscle improvement in zebrafish via increased heme oxygenase signaling
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Citation:
Hum Mol Genet. 2014 Apr 1;23(7):1869-78. doi: 10.1093/hmg/ddt579. Epub 2013 Nov 13 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is caused by a lack of the dystrophin protein and has no effective treatment at present.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kawahara G, Gasperini MJ, Myers JA, Widrick JJ, Eran A, Serafini PR, Alexander MS, Pletcher MT, Morris CA, Kunkel LM. Dystrophic muscle improvement in zebrafish via increased heme oxygenase signaling. Hum Mol Genet. 2014 Apr 1;23(7):1869-78. doi: 10.1093/hmg/ddt579. Epub 2013 Nov 13. |
Cellular visualization of macrophage pyroptosis and interleukin-1β release in a viral hemorrhagic infection in zebrafish larvae
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Citation:
J Virol. 2014 Oct;88(20):12026-40. doi: 10.1128/JVI.02056-14. Epub 2014 Aug 6 Epub:
Not Epub Abstract:
Hemorrhagic viral diseases are distributed worldwide with important pathogens, such as dengue virus or hantaviruses. The lack... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Varela M, Romero A, Dios S, van der Vaart M, Figueras A, Meijer AH, Novoa B. Cellular visualization of macrophage pyroptosis and interleukin-1β release in a viral hemorrhagic infection in zebrafish larvae. J Virol. 2014 Oct;88(20):12026-40. doi: 10.1128/JVI.02056-14. Epub 2014 Aug 6. |
MRI Virtual Biopsy and Treatment of Brain Metastatic Tumors with Targeted Nanobioconjugates
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Citation:
ACS Nano. 2015;[Epub ahead of print] doi:10.1021/acsnano.5b01872 Epub:
Yes Abstract:
Differential diagnosis of brain magnetic resonance imaging (MRI) enhancement(s) remains a significant problem, which may be... Delivery Method:
nanoparticle Organism or Cell Type:
mice Citation Extract: Patil P, Ljubimov AV, Gangalum PR, Ding H, Portilla-Arias J, Wagner S, Inoue S, Konda B, Rekechenetskiy A, Chesnokova A, Markman JL, Ljubimov VA, Li D, Prasad RS, Black KL, Holler E, Ljubimova JY. MRI Virtual Biopsy and Treatment of Brain Metastatic Tumors with Targeted Nanobioconjugates. ACS Nano. 2015;[Epub ahead of print] doi:10.1021/acsnano.5b01872 . |
Non-coding stem-bulge RNAs are required for cell proliferation and embryonic development in C. elegans
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Citation:
J Cell Sci. 2015;[Epub ahead of print]doi:10.1242/jcs.166744 Epub:
Yes Abstract:
Stem bulge RNAs (sbRNAs) are a family of small non-coding, stem-loop RNAs present in C. elegans and other nematodes, the... Delivery Method:
microinjection Organism or Cell Type:
Caenorhabditis elegans Citation Extract: Kowalski MP, Baylis HA, Krude T. Non-coding stem-bulge RNAs are required for cell proliferation and embryonic development in C. elegans. J Cell Sci. 2015;[Epub ahead of print]doi:10.1242/jcs.166744. |