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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Zebrafish her3 knockout impacts developmental and cancer-related gene signatures
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.02.25.482038 Epub:
Not Epub Abstract:
HES3 is a basic helix-loop-helix transcription factor that regulates neural stem cell renewal during development. HES3... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kent MR, Calderon D, Silvius KM, LaVigne CA, Cannon MV, Kendall GC. Zebrafish her3 knockout impacts developmental and cancer-related gene signatures. bioRxiv. 2022;[preprint] doi:10.1101/2022.02.25.482038. |
Antisense modulation of IL7R splicing to control sIL7R expression in human CD4+ T cells
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Citation:
bioRxiv. 2022;[preprint] doi:doi.org/10.1101/2022.02.22.481529 Epub:
Not Epub Abstract:
The interleukin 7 receptor (IL7R) is strongly associated with increased risk to develop multiple sclerosis (MS), an autoimmune... Delivery Method:
Endo-Porter PEG (HeLa), electroporation (primary CD4+ T) Organism or Cell Type:
cell culture: HeLa, human primary CD4+ T cells Citation Extract: Galarza-Muñoz G, Kennedy-Boone D, Schott G, Bradrick SS, Garcia-Blanco MA. Antisense modulation of IL7R splicing to control sIL7R expression in human CD4+ T cells. bioRxiv. 2022;[preprint] doi:doi.org/10.1101/2022.02.22.481529. |
Male infertility-associated Ccdc108 regulates multiciliogenesis via the intraflagellar transport machinery
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Citation:
EMBO Rep. 2022 Feb 24:e52775. doi: 10.15252/embr.202152775. Online ahead of print Epub:
Not Epub Abstract:
Motile cilia on the cell surface generate movement and directional fluid flow that is crucial for various biological processes... Delivery Method:
microinjection Organism or Cell Type:
Xenopus, zebrafish Citation Extract: Zhao H, Sun J, Insinna C, Lu Q, Wang Z, Nagashima K, Stauffer J, Andresson T, Specht S, Perera S, Daar IO, Westlake CJ. Male infertility-associated Ccdc108 regulates multiciliogenesis via the intraflagellar transport machinery. EMBO Rep. 2022 Feb 24:e52775. doi: 10.15252/embr.202152775. Online ahead of print. |
SRSF1 governs progenitor-specific alternative splicing to maintain adult epithelial tissue homeostasis and renewal
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Citation:
Dev Cell. 2022 Feb 22:S1534-5807(22)00036-3. doi: 10.1016/j.devcel.2022.01.011. Online ahead of print Epub:
Not Epub Abstract:
Alternative splicing generates distinct mRNA variants and is essential for development, homeostasis, and renewal. Proteins of... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: primary murine cells: dental epithelium, intestinal organoid crypt Citation Extract: Yu T, Cazares O, Tang AD, Kim HY, Wald T, Verma A, Liu Q, Barcellos-Hoff MH, Floor SN, Jung HS, Brooks AN, Klein OD. SRSF1 governs progenitor-specific alternative splicing to maintain adult epithelial tissue homeostasis and renewal. Dev Cell. 2022 Feb 22:S1534-5807(22)00036-3. doi: 10.1016/j.devcel.2022.01.011. Online ahead of print. |
A cell-based GEF assay reveals new substrates for DENN domains and a role for DENND2B in primary ciliogenesis
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Citation:
Sci Adv. 2022 Feb 25;8(8):eabk3088. doi: 10.1126/sciadv.abk3088. Epub 2022 Feb 23 Epub:
Not Epub Abstract:
Primary cilia are sensory antennae crucial for cell and organism development, and defects in their biogenesis cause... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kumar R, Francis V, Kulasekaran G, Khan M, Armstrong GAB, McPherson PS. A cell-based GEF assay reveals new substrates for DENN domains and a role for DENND2B in primary ciliogenesis. Sci Adv. 2022 Feb 25;8(8):eabk3088. doi: 10.1126/sciadv.abk3088. Epub 2022 Feb 23. |
Identification and establishment of type IV interferon and the characterization of interferon-upsilon including its class II cytokine receptors IFN-upsilonR1 and IL-10R2
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Citation:
Nat Commun. 2022 Feb 22;13(1):999. doi: 10.1038/s41467-022-28645-6 Epub:
Not Epub Abstract:
Interferons (IFNs) are critical soluble factors in the immune system and are composed of three types, (I, II and III) that... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen SN, Gan Z, Hou J, Yang YC, Huang L, Huang B, Wang S, Nie P. Identification and establishment of type IV interferon and the characterization of interferon-upsilon including its class II cytokine receptors IFN-upsilonR1 and IL-10R2. Nat Commun. 2022 Feb 22;13(1):999. doi: 10.1038/s41467-022-28645-6. |
FGF/MAPK/Ets signaling in Xenopus ectoderm contributes to neural induction and patterning in an autonomous and paracrine manner, respectively
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Citation:
Cells Dev. 2022 Feb 22;203769. doi: 10.1016/j.cdev.2022.203769. Online ahead of print Epub:
Not Epub Abstract:
FGF and anti-BMP signals from the organizer of mesodermal origin are essential for Xenopus neural development from gastrula... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Hongo I, Okamoto H. FGF/MAPK/Ets signaling in Xenopus ectoderm contributes to neural induction and patterning in an autonomous and paracrine manner, respectively. Cells Dev. 2022 Feb 22;203769. doi: 10.1016/j.cdev.2022.203769. Online ahead of print. |
Gene duplication, conservation, and divergence of activating transcription factor 5 gene in zebrafish
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Citation:
J Exp Zool B Mol Dev Evol. 2022 Feb 28. doi: 10.1002/jez.b.23124. Online ahead of print Epub:
Yes Abstract:
Activating transcription factor 5 (Atf5) is a member of the ATF/CREB family of transcription factors and involved in diverse... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhu H, Zhang X, Xu S, Wu J, Hou M, Zhao H, Zhou Q, Zhong X. Gene duplication, conservation, and divergence of activating transcription factor 5 gene in zebrafish. J Exp Zool B Mol Dev Evol. 2022 Feb 28. doi: 10.1002/jez.b.23124. Online ahead of print. |
Transforming growth factor-β1/Thrombospondin-1/CD47 axis mediates dysfunction in CD34+ cells derived from diabetic older adults
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Citation:
Eur J Pharmacol. 2022 Feb 23;920:174842. doi: 10.1016/j.ejphar.2022.174842. Online ahead of print Epub:
Not Epub Abstract:
Aging with diabetes is associated with impaired vasoprotective functions and decreased nitric oxide (NO) generation in CD34+... Organism or Cell Type:
cell culture: CD34+ (diabetic/non-diabetic) Citation Extract: Jahan J, Monte de Oca I, Meissner B, Joshi S, Maghrabi A, Quiroz-Olvera J, Lopez-Yang C, Bartelmez SH, Garcia C, Jarajapu YP. Transforming growth factor-β1/Thrombospondin-1/CD47 axis mediates dysfunction in CD34+ cells derived from diabetic older adults. Eur J Pharmacol. 2022 Feb 23;920:174842. doi: 10.1016/j.ejphar.2022.174842. Online ahead of print. |
In Vitro Delivery of PMOs in Myoblasts by Electroporation
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Citation:
Methods Mol Biol. 2022;2434:191-205. doi: 10.1007/978-1-0716-2010-6_12 Epub:
Not Epub Abstract:
Antisense oligonucleotides (AONs) are small synthetic molecules of therapeutic interest for a variety of human disease. Their... Delivery Method:
electroporation Organism or Cell Type:
cell culture: myoblasts Citation Extract: Goossens R, Aartsma-Rus A. In Vitro Delivery of PMOs in Myoblasts by Electroporation. Methods Mol Biol. 2022;2434:191-205. doi: 10.1007/978-1-0716-2010-6_12. |