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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Kinesin motor KIFC1 is required for tubulin acetylation and actin-dependent spindle migration in mouse oocyte meiosis
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Citation:
Development. 2022;149(5):dev200231. doi:10.1242/dev.200231 Epub:
Not Epub Abstract:
Mammalian oocyte maturation is a unique asymmetric division, which is mainly because of actin-based spindle migration to the... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Shan M-M, Zou Y-J, Pan Z-N, Zhang H-L, Xu Y, Ju J-Q, Sun S-C. Kinesin motor KIFC1 is required for tubulin acetylation and actin-dependent spindle migration in mouse oocyte meiosis. Development. 2022;149(5):dev200231. doi:10.1242/dev.200231. |
Morpholino-driven blockade of Dkk-1 in osteosarcoma inhibits bone damage and tumour expansion by multiple mechanisms
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Citation:
Br J Cancer. 2022 Jul;127(1):43-55. doi: 10.1038/s41416-022-01764-z. Epub 2022 Mar 11 Epub:
Not Epub Abstract:
Background: Osteosarcoma (OS) is the most common primary bone malignancy. Chemotherapy plays an essential role in OS treatment... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: (RFP)-labeled MOSJ-Dkk1 murine osteochondral sarcoma line, xenograft in Foxn1-/Foxn1- mice Citation Extract: Pan S, Cesarek M, Godoy C, Co CM, Schindler C, Padilla K, Haskell A, Barreda H, Story C, Poole R, Dabney A, Gregory CA. Morpholino-driven blockade of Dkk-1 in osteosarcoma inhibits bone damage and tumour expansion by multiple mechanisms. Br J Cancer. 2022 Jul;127(1):43-55. doi: 10.1038/s41416-022-01764-z. Epub 2022 Mar 11. |
Rbbp4 loss disrupts neural progenitor cell cycle regulation independent of Rb and leads to Tp53 acetylation and apoptosis
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Citation:
Dev Dyn. 2022 Mar 9. doi: 10.1002/dvdy.467. Online ahead of print Epub:
Not Epub Abstract:
Background: Retinoblastoma-binding protein 4 (Rbbp4) is a component of transcription regulatory complexes that control cell... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Schultz-Rogers LE, Thayer ML, Kambakam S, Wierson WA, Helmer JA, Wishman MD, Wall KA, Greig JL, Forsman JL, Puchhalapalli K, Nair S, Weiss TJ, Luiken JM, Blackburn PR, Ekker SC, Kool M, McGrail M. Rbbp4 loss disrupts neural progenitor cell cycle regulation independent of Rb and leads to Tp53 acetylation and apoptosis. Dev Dyn. 2022 Mar 9. doi: 10.1002/dvdy.467. Online ahead of print. |
SIK2 maintains breast cancer stemness by phosphorylating LRP6 and activating Wnt/β-catenin signaling
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Citation:
Oncogene. 2022;[Epub] doi:10.1038/s41388-022-02259-0 Epub:
Yes Abstract:
Breast cancer stem cells (BCSCs) are the main drivers of recurrence and metastasis. However, commonly used drugs rarely target... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rong Z, Zhang L, Li Z, Xiao Z, Duan Y, Ren X, Zi Y, Gao J, Mu Y, Guan Y, Cao Z, Wang X, Pei Q, Zeng Y, Fan Q, Zeng Z, Ou D, He J, Nie Y, Tan R, Weng L, Li Y, Xiang R, Deng Y, Sun L. SIK2 maintains breast cancer stemness by phosphorylating LRP6 and activating Wnt/β-catenin signaling. Oncogene. 2022;[Epub] doi:10.1038/s41388-022-02259-0. |
Integration of vascular progenitors into functional blood vessels represents a distinct mechanism of vascular growth
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Citation:
Dev Cell. 2022 Mar 28;57(6):767-782.e6. doi: 10.1016/j.devcel.2022.02.015. Epub 2022 Mar 10. Epub:
Not Epub Abstract:
During embryogenesis, the initial vascular network forms by the process of vasculogenesis, or the specification of vascular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Metikala S, Warkala M, Chetty SC, Chestnut B, Florat DR, Plender E, Nester O, Koenig AL, Astrof S, Sumanas S. Integration of vascular progenitors into functional blood vessels represents a distinct mechanism of vascular growth. Dev Cell. 2022 Mar 28;57(6):767-782.e6. doi: 10.1016/j.devcel.2022.02.015. Epub 2022 Mar 10. . |
ALKBH3-dependent m1A demethylation of Aurora A mRNA inhibits ciliogenesis
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Citation:
Cell Discov. 2022;8(1):25 doi:10.1038/s41421-022-00385-3 Epub:
Not Epub Abstract:
Primary cilia are antenna-like subcellular structures to act as signaling platforms to regulate many cellular processes and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kuang W, Jin H, Yang F, Chen X, Liu J, Li T, Chang Y, Liu M, Xu Z, Huo C, Yan X, Yang Y, Liu W, Shu Q, Xie S, Zhou T. ALKBH3-dependent m1A demethylation of Aurora A mRNA inhibits ciliogenesis. Cell Discov. 2022;8(1):25 doi:10.1038/s41421-022-00385-3. |
Electron Transfer Flavoprotein (ETF) α Controls Blood Vessel Development by Regulating Endothelial Mitochondrial Bioenergetics and Oxygen Consumption
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Citation:
Oxid Med Cell Longev. 2022;2022:7969916 [Epub] doi:10.1155/2022/7969916 Epub:
Yes Abstract:
While impairment of vascular homeostasis induced by hypercholesterolemia is the first step of cardiovascular diseases, the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yan Y, Xu Y, Yang X, Li Z, Niu K, Liu C, Zhao M, Xiao Q,Wu W. Electron Transfer Flavoprotein (ETF) α Controls Blood Vessel Development by Regulating Endothelial Mitochondrial Bioenergetics and Oxygen Consumption. Oxid Med Cell Longev. 2022;2022:7969916 [Epub] doi:10.1155/2022/7969916. |
Recent reconfiguration of an ancient developmental gene regulatory network in Heliocidaris sea urchins
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.03.03.482868 Epub:
Not Epub Abstract:
Changes in developmental gene regulatory networks (dGRNs) underlie much of the diversity of life1, but the evolutionary... Delivery Method:
microinjection Organism or Cell Type:
Heliocidaris erythrogramma (sea urchin) Citation Extract: Davidson PL, Guo H, Swart JS, Massri AJ, Edgar A, Wang L, Berrio A, Devens HR, Koop D, Cisternas P, Zhang H, Zhang Y, Byrne M, Fan G, Wray GA. Recent reconfiguration of an ancient developmental gene regulatory network in Heliocidaris sea urchins. bioRxiv. 2022;[preprint] doi:10.1101/2022.03.03.482868. |
Alcam-a and Pdgfr-α are essential for the development of sclerotome derived stromal cells that support hematopoiesis in vivo
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.03.02.482709 Epub:
Not Epub Abstract:
Mesenchymal stromal cells are essential components of hematopoietic stem and progenitor cell (HSPC) niches, regulating HSPC... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Murayama E, Vivier C, Schmidt A, Touret A-L, Herbomel P. Alcam-a and Pdgfr-α are essential for the development of sclerotome derived stromal cells that support hematopoiesis in vivo. bioRxiv. 2022;[preprint] doi:10.1101/2022.03.02.482709 . |
Oligodendrocyte precursor cells sculpt the visual system by regulating axonal remodeling
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Citation:
Nat Neurosci. 2022;25:280-4. doi:10.1038/s41593-022-01023-7 Epub:
Not Epub Abstract:
Many oligodendrocyte precursor cells (OPCs) do not differentiate to form myelin, suggesting additional roles of this cell... Organism or Cell Type:
zebrafish Citation Extract: Xiao Y, Petrucco L, Hoodless LJ, Portugues R, Czopka T. Oligodendrocyte precursor cells sculpt the visual system by regulating axonal remodeling. Nat Neurosci. 2022;25:280-4. doi:10.1038/s41593-022-01023-7. |