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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Negative Elongation Factor (NELF) Inhibits Premature Granulocytic Development in Zebrafish

Authors:
Huang M, Ahmed A, Wang W, Wang X, Ma C, Jiang H, Li W, Jing L
Citation:
Int J Mol Sci. 2022;23(7):3833. doi:10.3390/ijms23073833
Epub:
Not Epub
Abstract:
Gene expression is tightly regulated during hematopoiesis. Recent studies have suggested that RNA polymerase II (Pol II)...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Huang M, Ahmed A, Wang W, Wang X, Ma C, Jiang H, Li W, Jing L . Negative Elongation Factor (NELF) Inhibits Premature Granulocytic Development in Zebrafish. Int J Mol Sci. 2022;23(7):3833. doi:10.3390/ijms23073833 .

Notch1 is asymmetrically distributed from the beginning of embryogenesis and controls the ventral center

Authors:
Castro Colabianchi AM, Revinski DR, Encinas PI, Baez MV, Monti RJ, Rodríguez Abinal M, Kodjabachian L, Franchini LF, López SL
Citation:
Development. 2018 Jul 17;145(14):dev159368. doi:10.1242/dev.159368
Epub:
Not Epub
Abstract:
Based on functional evidence, we have previously demonstrated that early ventral Notch1 activity restricts dorsoanterior...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Castro Colabianchi AM, Revinski DR, Encinas PI, Baez MV, Monti RJ, Rodríguez Abinal M, Kodjabachian L, Franchini LF, López SL. Notch1 is asymmetrically distributed from the beginning of embryogenesis and controls the ventral center. Development. 2018 Jul 17;145(14):dev159368. doi:10.1242/dev.159368.

Hand2 delineates mesothelium progenitors and is reactivated in mesothelioma

Authors:
Prummel KD, Crowell HL, Nieuwenhuize S, Brombacher EC, Daetwyler S, Soneson C, Kresoja-Rakic J, Kocere A, Ronner M, Ernst A, Labbaf Z, Clouthier DE, Firulli AB, Sánchez-Iranzo H, Naganathan SR, O’Rourke R, Raz E, Mercader N, Burger A, Felley-Bosco E, Huisken J, Robinson MD, Mosimann C
Citation:
Nat Commun. 2022;13(1):1677. doi:10.1038/s41467-022-29311-7
Epub:
Not Epub
Abstract:
The mesothelium lines body cavities and surrounds internal organs, widely contributing to homeostasis and regeneration....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Prummel KD, Crowell HL, Nieuwenhuize S, Brombacher EC, Daetwyler S, Soneson C, Kresoja-Rakic J, Kocere A, Ronner M, Ernst A, Labbaf Z, Clouthier DE, Firulli AB, Sánchez-Iranzo H, Naganathan SR, O’Rourke R, Raz E, Mercader N, Burger A, Felley-Bosco E, Huisken J, Robinson MD, Mosimann C. Hand2 delineates mesothelium progenitors and is reactivated in mesothelioma. Nat Commun. 2022;13(1):1677. doi:10.1038/s41467-022-29311-7.

Dnmt1 is required for the development of auditory organs via cell cycle arrest and Fgf signalling

Authors:
Tang D, Zheng S, Zheng Z, Liu C, Zhang J, Yan R, Wu C, Zuo N, Wu L, Xu H, Liu S, He Y
Citation:
Cell Prolif. 2022 Mar 29:e13225. doi: 10.1111/cpr.13225. Online ahead of print
Epub:
Yes
Abstract:
Objectives: To explore the role of DNA methyltransferase 1 (DNMT1) in the development of auditory system using zebrafish as...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tang D, Zheng S, Zheng Z, Liu C, Zhang J, Yan R, Wu C, Zuo N, Wu L, Xu H, Liu S, He Y. Dnmt1 is required for the development of auditory organs via cell cycle arrest and Fgf signalling. Cell Prolif. 2022 Mar 29:e13225. doi: 10.1111/cpr.13225. Online ahead of print.

Genome-wide analysis identified novel susceptible genes of restless legs syndrome in migraineurs

Authors:
Jiang YJ, Fann CS, Fuh JL, Chung MY, Huang HY, Chu KC, Wang YF, Hsu CL, Kao LS, Chen SP, Wang SJ
Citation:
J Headache Pain. 2022 Mar 29;23(1):39. doi: 10.1186/s10194-022-01409-9
Epub:
Not Epub
Abstract:
Background: Restless legs syndrome is a highly prevalent comorbidity of migraine; however, its genetic contributions remain...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jiang YJ, Fann CS, Fuh JL, Chung MY, Huang HY, Chu KC, Wang YF, Hsu CL, Kao LS, Chen SP, Wang SJ. Genome-wide analysis identified novel susceptible genes of restless legs syndrome in migraineurs. J Headache Pain. 2022 Mar 29;23(1):39. doi: 10.1186/s10194-022-01409-9.

A recessive variant in SIM2 in a child with complex craniofacial anomalies and global developmental delay

Authors:
Al-Kurbi AA, Da'as SI, Aamer W, Krishnamoorthy N, Poggiolini I, Abdelrahman D, Elbashir N, Al-Shabeeb Akil A, Glass GE, Fakhro KA
Citation:
Eur J Med Genet. 2022 Apr;65(4):104455. doi: 10.1016/j.ejmg.2022.104455. Epub 2022 Feb 16
Epub:
Not Epub
Abstract:
Rare deletions and duplications on the long arm of Chromosome 21 have previously been reported in many patients with...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Al-Kurbi AA, Da'as SI, Aamer W, Krishnamoorthy N, Poggiolini I, Abdelrahman D, Elbashir N, Al-Shabeeb Akil A, Glass GE, Fakhro KA. A recessive variant in SIM2 in a child with complex craniofacial anomalies and global developmental delay. Eur J Med Genet. 2022 Apr;65(4):104455. doi: 10.1016/j.ejmg.2022.104455. Epub 2022 Feb 16.

Somatic MAP3K3 and PIK3CA mutations in sporadic cerebral and spinal cord cavernous malformations

Authors:
Hong T, Xiao X, Ren J, Cui B, Zong Y, Zou J, Kou Z, Jiang N, Meng G, Zeng G, Shan Y, Wu H, Chen Z, Liang J, Xiao X, Tang J, Wei Y, Ye M, Sun L, Li G, Hu P, Hui R, Zhang H, Wang Y
Citation:
Brain. 2021 Oct 22;144(9):2648-2658. doi: 10.1093/brain/awab117
Epub:
Not Epub
Abstract:
Cavernous malformations affecting the CNS occur in ∼0.16-0.4% of the general population. The majority (85%) of cavernous...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hong T, Xiao X, Ren J, Cui B, Zong Y, Zou J, Kou Z, Jiang N, Meng G, Zeng G, Shan Y, Wu H, Chen Z, Liang J, Xiao X, Tang J, Wei Y, Ye M, Sun L, Li G, Hu P, Hui R, Zhang H, Wang Y. Somatic MAP3K3 and PIK3CA mutations in sporadic cerebral and spinal cord cavernous malformations. Brain. 2021 Oct 22;144(9):2648-2658. doi: 10.1093/brain/awab117.

miR-731 modulates the zebrafish heart morphogenesis via targeting Calcineurin/Nfatc3a pathway

Authors:
Huang Y, Wang W-F, Huang C-X, Li X-H, Liu H, Wang H-L
Citation:
Biochim Biophys Acta Gen Subj. 2022;1866(6):130133. doi:10.1016/j.bbagen.2022.130133
Epub:
Not Epub
Abstract:
Background: Zebrafish miR-731 is orthologous of human miR-425, which has been demonstrated to have cardio-protective roles by a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Huang Y, Wang W-F, Huang C-X, Li X-H, Liu H, Wang H-L. miR-731 modulates the zebrafish heart morphogenesis via targeting Calcineurin/Nfatc3a pathway. Biochim Biophys Acta Gen Subj. 2022;1866(6):130133. doi:10.1016/j.bbagen.2022.130133.

LAMP2A regulates the loading of proteins into exosomes

Authors:
Ferreira JV, da Rosa Soares A, Ramalho J, Carvalho CM, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P
Citation:
Sci Adv. 2022;8(12):[Epub] doi:10.1126/sciadv.abm1140
Epub:
Not Epub
Abstract:
Exosomes are extracellular vesicles of endosomal origin that are released by practically all cell types across metazoans....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ferreira JV, da Rosa Soares A, Ramalho J, Carvalho CM, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P. LAMP2A regulates the loading of proteins into exosomes. Sci Adv. 2022;8(12):[Epub] doi:10.1126/sciadv.abm1140.

Nitric Oxide Signals Through IRAG to Inhibit TRPM4 Channels and Dilate Cerebral Arteries

Authors:
Ali S, Solano AS, Gonzales AL, Thakore P, Krishnan V, Yamasaki E, Earley S
Citation:
Function (Oxf). 2021 Oct 9;2(6):zqab051. doi: 10.1093/function/zqab051. eCollection 2021
Epub:
Not Epub
Abstract:
Nitric oxide (NO) relaxes vascular smooth muscle cells (SMCs) and dilates blood vessels by increasing intracellular levels of...
Delivery Method:
lipofectamine 2000
Organism or Cell Type:
explants: cerebral arteries
Citation Extract:
Ali S, Solano AS, Gonzales AL, Thakore P, Krishnan V, Yamasaki E, Earley S. Nitric Oxide Signals Through IRAG to Inhibit TRPM4 Channels and Dilate Cerebral Arteries. Function (Oxf). 2021 Oct 9;2(6):zqab051. doi: 10.1093/function/zqab051. eCollection 2021.

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