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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
VPS28 regulates brain vasculature by controlling neuronal VEGF trafficking through extracellular vesicle secretion
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Citation:
iScience. 2022 Mar 9;25(4):104042. doi: 10.1016/j.isci.2022.104042. eCollection 2022 Apr 15 Epub:
Not Epub Abstract:
Extracellular vesicles (EVs) participate in intercellular communication and contribute to the angiogenesis. However, the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dong X, Jiang D, Wang L, Zhao J, Yu L, Huang Y, Wu X, Zhu Y, Zhao Y, Zhao Q, Zhang G, Li X. VPS28 regulates brain vasculature by controlling neuronal VEGF trafficking through extracellular vesicle secretion. iScience. 2022 Mar 9;25(4):104042. doi: 10.1016/j.isci.2022.104042. eCollection 2022 Apr 15. |
In-Cell Penetration Selection-Mass Spectrometry Produces Noncanonical Peptides for Antisense Delivery
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.04.13.488231 Epub:
Not Epub Abstract:
Peptide-mediated delivery of macromolecules in cells has significant potential therapeutic benefits, but no therapy employing... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: HeLa 654 Citation Extract: Schissel CK, Farquhar CE, Loas A, Malmberg AB, Pentelute BL. In-Cell Penetration Selection-Mass Spectrometry Produces Noncanonical Peptides for Antisense Delivery. bioRxiv. 2022;[preprint] doi:10.1101/2022.04.13.488231. |
Synthesis of Morpholino Nucleosides Starting From Enantiopure Glycidol
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Citation:
Org Chem Front. 2022;[Epub] doi:10.1039/D2QO00400C Epub:
Yes Abstract:
A protocol for the synthesis of modified morpholino monomers was performed in few steps through the condensation between 6-... Citation Extract: Papis M, Loro C, Penso M, Broggini G, Foschi F. Synthesis of Morpholino Nucleosides Starting From Enantiopure Glycidol. Org Chem Front. 2022;[Epub] doi:10.1039/D2QO00400C. |
Functional Study of TMEM163 Gene Variants Associated with Hypomyelination Leukodystrophy
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Citation:
Cells. 2022;11(8):1285. doi:10.3390/cells11081285 Epub:
Not Epub Abstract:
Hypomyelinating leukodystrophies (HLDs) are a rare group of heterogeneously genetic disorders characterized by persistent... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yan H, Yang S, Hou Y, Ali S, Escobar A, Gao K, Duan R, Kubisiak T, Wang J, Zhang Y, Xiao J, Jiang Y, Zhang T, Wu Y, Burmeister M, Wang Q, Cuajungco MP, Wang J. Functional Study of TMEM163 Gene Variants Associated with Hypomyelination Leukodystrophy. Cells. 2022;11(8):1285. doi:10.3390/cells11081285. |
Trim33 conditions the lifespan of primitive macrophages and onset of definitive macrophage production
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.04.06.487382 Epub:
Not Epub Abstract:
TRIM33 (Tif1-γ) is a transcriptional regulator notably involved in several aspects of hematopoiesis. It is essential for the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Demy DL, Touret A-L, Lancino M, Tauzin M, Capuana L, Pierre C, Herbomel P. Trim33 conditions the lifespan of primitive macrophages and onset of definitive macrophage production. bioRxiv. 2022;[preprint] doi:10.1101/2022.04.06.487382. |
The CHARGE syndrome ortholog CHD-7 regulates TGF-β pathways in Caenorhabditis elegans
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Citation:
Proc Natl Acad Sci U S A. 2022 Apr 12;119(15):e2109508119. doi: 10.1073/pnas.2109508119. Epub 2022 Apr 8 Epub:
Not Epub Abstract:
CHARGE syndrome is a complex developmental disorder caused by mutations in the chromodomain helicase DNA-binding protein-7 (... Organism or Cell Type:
Xenopus laevis Citation Extract: Jofré DM, Hoffman DK, Cervino AS, Hahn GM, Grundy M, Yun S, Amrit FRG, Stolz DB, Godoy LF, Salvatore E, Rossi FA, Ghazi A, Cirio MC, Yanowitz JL, Hochbaum D. The CHARGE syndrome ortholog CHD-7 regulates TGF-β pathways in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 2022 Apr 12;119(15):e2109508119. doi: 10.1073/pnas.2109508119. Epub 2022 Apr 8. |
Sema6D Regulates Zebrafish Vascular Patterning and Motor Neuronal Axon Growth in Spinal Cord
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Citation:
Front Mol Neurosci. 2022;15:[Epub] doi:10.3389/fnmol.2022.854556 Epub:
Yes Abstract:
Vessels and nerves are closely associated in anatomy as well as functions. Accumulating evidences have demonstrated that axon-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sheng J, Xu J, Geng K, Liu D. Sema6D Regulates Zebrafish Vascular Patterning and Motor Neuronal Axon Growth in Spinal Cord. Front Mol Neurosci. 2022;15:[Epub] doi:10.3389/fnmol.2022.854556. |
Colorimetric aptasensor for sensitive detection of quinclorac based on exonuclease III-assisted cyclic release of phosphorodiamidate morpholino oligomer mimic enzyme strategy
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Citation:
Anal Chim Acta . 2022 May 15;1207:339815. doi: 10.1016/j.aca.2022.339815. Epub 2022 Apr 8. Epub:
Not Epub Abstract:
Here, a colorimetric aptasensor was constructed for sensitively detecting quinclorac (QNC), a common herbicide. The aptasensor... Citation Extract: Yang L, Ye X, Li X, Huang Z, Chen F, Yang W, Wang Z. Colorimetric aptasensor for sensitive detection of quinclorac based on exonuclease III-assisted cyclic release of phosphorodiamidate morpholino oligomer mimic enzyme strategy. Anal Chim Acta . 2022 May 15;1207:339815. doi: 10.1016/j.aca.2022.339815. Epub 2022 Apr 8. . |
Developmental maturation of the hematopoietic system controlled by a Lin28b-let-7-Cbx2 axis
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Citation:
Cell Rep. 2022 Apr 5;39(1):110587. doi:10.1016/j.celrep.2022.110587 Epub:
Not Epub Abstract:
Hematopoiesis changes over life to meet the demands of maturation and aging. Here, we find that the definitive hematopoietic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wang D, Tanaka-Yano M, Meader E, Kinney MA, Morris V, Lummertz da Rocha E, Liu N, Liu T, Zhu Q, Orkin SH, North TE, Daley GQ, Rowe RG. Developmental maturation of the hematopoietic system controlled by a Lin28b-let-7-Cbx2 axis. Cell Rep. 2022 Apr 5;39(1):110587. doi:10.1016/j.celrep.2022.110587. |
Single Stranded Fully Modified-Phosphorothioate Oligonucleotides can Induce Structured Nuclear Inclusions, Alter Nuclear Protein Localization and Disturb the Transcriptome In Vitro
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Citation:
Front Genet. 2022;13:791416. doi:10.3389/fgene.2022.791416 Epub:
Not Epub Abstract:
Oligonucleotides and nucleic acid analogues that alter gene expression are now showing therapeutic promise in human disease.... Delivery Method:
cell bathing or electroporation or Morpholino-DNA heteroduplexes with lipofectamine Organism or Cell Type:
cell culture: fibroblasts, U2OS Citation Extract: Flynn LL, Li R, Pitout IL, Aung-Htut MT, Larcher LM, Cooper JAL, Greer KL, Hubbard A, Griffiths L, Bond CS, Wilton SD, Fox AH, Fletcher S. Single Stranded Fully Modified-Phosphorothioate Oligonucleotides can Induce Structured Nuclear Inclusions, Alter Nuclear Protein Localization and Disturb the Transcriptome In Vitro. Front Genet. 2022;13:791416. doi:10.3389/fgene.2022.791416. |