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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Zic5 stabilizes Gli3 via a non-transcriptional mechanism during retinal development

Authors:
Sun J, Yoon J, Lee M, Lee H-K, Hwang Y-S, Daar IO
Citation:
Cell Rep. 2022;38(5):110312 doi:10.1016/j.celrep.2022.110312
Epub:
Not Epub
Abstract:
The Zic family of zinc finger transcription factors plays a critical role in multiple developmental processes. Using loss-of-...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Sun J, Yoon J, Lee M, Lee H-K, Hwang Y-S, Daar IO. Zic5 stabilizes Gli3 via a non-transcriptional mechanism during retinal development. Cell Rep. 2022;38(5):110312 doi:10.1016/j.celrep.2022.110312.

Prdm16 and Notch functionally and physically interact during artery development

Authors:
Beerens M, Van Wauwe J, Craps S, Daems M, Ashmita KC, Finck C, Wright S, Leigh ND, MacRae CA, Luttun A
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.12.05.471275
Epub:
Not Epub
Abstract:
Proper vascular function requires correct arteriovenous (AV) endothelial cell (EC) differentiation. While Notch and its...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Beerens M, Van Wauwe J, Craps S, Daems M, Ashmita KC, Finck C, Wright S, Leigh ND, MacRae CA, Luttun A. Prdm16 and Notch functionally and physically interact during artery development. bioRxiv. 2021;[preprint] doi:10.1101/2021.12.05.471275.

RNA Localization in Confined Cells Depends on Cellular Mechanical Activity and Contributes to Confined Migration

Authors:
Moriarty RA, Mili S, Stroka KM
Citation:
iScience. 2022;[Epub ahead of print] doi:10.2139/ssrn.3878411
Epub:
Not Epub
Abstract:
Cancer cells experience mechanical confining forces during metastasis and consequently, can alter their migratory mechanisms....
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture:A375, MB-231
Citation Extract:
Moriarty RA, Mili S, Stroka KM. RNA Localization in Confined Cells Depends on Cellular Mechanical Activity and Contributes to Confined Migration. iScience. 2022;[Epub ahead of print] doi:10.2139/ssrn.3878411 .

Oxidative pentose phosphate pathway controls vascular mural cell coverage by regulating extracellular matrix composition

Authors:
Facchinello N, Astone M, Audano M, Oberkersch RE, Spizzotin M, Calura E, Marques M, Crisan M, Mitro N, Santoro MM
Citation:
Nat Metab. 2022;4:123-40. doi:10.1038/s42255-021-00514-4
Epub:
Not Epub
Abstract:
Vascular mural cells (vMCs) play an essential role in the development and maturation of the vasculature by promoting vessel...
Organism or Cell Type:
zebrafish
Citation Extract:
Facchinello N, Astone M, Audano M, Oberkersch RE, Spizzotin M, Calura E, Marques M, Crisan M, Mitro N, Santoro MM. Oxidative pentose phosphate pathway controls vascular mural cell coverage by regulating extracellular matrix composition. Nat Metab. 2022;4:123-40. doi:10.1038/s42255-021-00514-4.

Neuregulin 1 is required for the development of enteric neurons and vagus in zebrafish

Authors:
Jiang M, Pu J-R, Yang D-H, Zhang X, Tang S-T
Citation:
Int J Clin Exp Pathol. 2016;9(2):1416-1423
Epub:
Not Epub
Abstract:
Hirschsprung’s disease (HSCR) is a congenital malformation of the colon characterised by the absence of enteric ganglion in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jiang M, Pu J-R, Yang D-H, Zhang X, Tang S-T. Neuregulin 1 is required for the development of enteric neurons and vagus in zebrafish. Int J Clin Exp Pathol. 2016;9(2):1416-1423.

Augmented ERAD (ER-associated degradation) activity in chondrocytes is necessary for cartilage development and maintenance

Authors:
Sim HJ, Cho C, Kim HE, Hong JY, Song EK, Kwon KY, Jang DG, Kim SJ, Lee HS, Lee C, Kwon T, Yang S, Park TJ
Citation:
Sci Adv. 2022 Jan 21;8(3):eabl4222. doi: 10.1126/sciadv.abl4222. Epub 2022 Jan 21
Epub:
Not Epub
Abstract:
Chondrocytes secrete massive extracellular matrix (ECM) molecules that are produced, folded, and modified in the endoplasmic...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Sim HJ, Cho C, Kim HE, Hong JY, Song EK, Kwon KY, Jang DG, Kim SJ, Lee HS, Lee C, Kwon T, Yang S, Park TJ. Augmented ERAD (ER-associated degradation) activity in chondrocytes is necessary for cartilage development and maintenance. Sci Adv. 2022 Jan 21;8(3):eabl4222. doi: 10.1126/sciadv.abl4222. Epub 2022 Jan 21.

Genomic and physiological analyses of the zebrafish atrioventricular canal reveal molecular building blocks of the secondary pacemaker region

Authors:
Abu Nahia K, Migdał M, Quinn TA, Poon KL, Łapiński M, Sulej A, Liu J, Mondal SS, Pawlak M, Bugajski Ł, Piwocka K, Brand T, Kohl P, Korzh V, Winata C
Citation:
Cell Mol Life Sci. 2021 Oct;78(19-20):6669-6687. doi: 10.1007/s00018-021-03939-y. Epub 2021 Sep 23
Epub:
Not Epub
Abstract:
The atrioventricular canal (AVC) is the site where key structures responsible for functional division between heart regions are...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Abu Nahia K, Migdał M, Quinn TA, Poon KL, Łapiński M, Sulej A, Liu J, Mondal SS, Pawlak M, Bugajski Ł, Piwocka K, Brand T, Kohl P, Korzh V, Winata C. Genomic and physiological analyses of the zebrafish atrioventricular canal reveal molecular building blocks of the secondary pacemaker region. Cell Mol Life Sci. 2021 Oct;78(19-20):6669-6687. doi: 10.1007/s00018-021-03939-y. Epub 2021 Sep 23.

Ribosome slowdown triggers codon-mediated mRNA decay independently of ribosome quality control

Authors:
Mishima Y, Han P, Ishibashi K, Kimura S, Iwasaki S
Citation:
EMBO J. 2022 Jan 18:e109256. doi: 10.15252/embj.2021109256. Online ahead of print
Epub:
Yes
Abstract:
The control of mRNA stability plays a central role in regulating gene expression patterns. Recent studies have revealed that...
Organism or Cell Type:
zebrafish
Citation Extract:
Mishima Y, Han P, Ishibashi K, Kimura S, Iwasaki S. Ribosome slowdown triggers codon-mediated mRNA decay independently of ribosome quality control. EMBO J. 2022 Jan 18:e109256. doi: 10.15252/embj.2021109256. Online ahead of print.

Lrrcc1 and Ccdc61 are conserved effectors of multiciliated cell function

Authors:
Nommick A, Boutin C, Rosnet O, Schirmer C, Bazellières E, Thomé V, Loiseau E, Viallat A, Kodjabachian L
Citation:
J Cell Sci. 2022 Jan 24:jcs.258960. doi: 10.1242/jcs.258960. Online ahead of print
Epub:
Yes
Abstract:
Ciliated epithelia perform essential functions across animal evolution, ranging from locomotion of marine organisms to...
Organism or Cell Type:
Xenopus
Citation Extract:
Nommick A, Boutin C, Rosnet O, Schirmer C, Bazellières E, Thomé V, Loiseau E, Viallat A, Kodjabachian L. Lrrcc1 and Ccdc61 are conserved effectors of multiciliated cell function. J Cell Sci. 2022 Jan 24:jcs.258960. doi: 10.1242/jcs.258960. Online ahead of print.

Murine AGM single-cell profiling identifies a continuum of hemogenic endothelium differentiation marked by ACE

Authors:
Fadlullah MZH, Neo WH, Lie-A-Ling M, Thambyrajah R, Patel R, Mevel R, Aksoy I, Do Khoa N, Savatier P, Fontenille L, Baker SM, Rattray M, Kouskoff V, Lacaud G
Citation:
Blood. 2022 Jan 20;139(3):343-356. doi: 10.1182/blood.2020007885
Epub:
Not Epub
Abstract:
In vitro generation and expansion of hematopoietic stem cells (HSCs) holds great promise for the treatment of any ailment that...
Organism or Cell Type:
mouse embryo
Citation Extract:
Fadlullah MZH, Neo WH, Lie-A-Ling M, Thambyrajah R, Patel R, Mevel R, Aksoy I, Do Khoa N, Savatier P, Fontenille L, Baker SM, Rattray M, Kouskoff V, Lacaud G. Murine AGM single-cell profiling identifies a continuum of hemogenic endothelium differentiation marked by ACE. Blood. 2022 Jan 20;139(3):343-356. doi: 10.1182/blood.2020007885.

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