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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

RES complex is associated with intron definition and required for zebrafish early embryogenesis

Authors:
Fernandez JP, Moreno-Mateos MA, Gohr A, Miao L, Chan SH, Irimia M, Giraldez AJ
Citation:
PLoS Genet. 2018 Jul 3;14(7):e1007473. doi: 10.1371/journal.pgen.1007473. eCollection 2018 Jul
Epub:
Not Epub
Abstract:
Pre-mRNA splicing is a critical step of gene expression in eukaryotes. Transcriptome-wide splicing patterns are complex and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fernandez JP, Moreno-Mateos MA, Gohr A, Miao L, Chan SH, Irimia M, Giraldez AJ. RES complex is associated with intron definition and required for zebrafish early embryogenesis. PLoS Genet. 2018 Jul 3;14(7):e1007473. doi: 10.1371/journal.pgen.1007473. eCollection 2018 Jul.

Pitx2c orchestrates embryonic axis extension via mesendodermal cell migration

Authors:
Collins MM, Maischein HM, Dufourcq P, Charpentier M, Blader P, Stainier DY
Citation:
Elife. 2018 Jun 28;7. pii: e34880. doi: 10.7554/eLife.34880
Epub:
Not Epub
Abstract:
Pitx2c, a homeodomain transcription factor, is classically known for its left-right patterning role. However, an early wave of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Collins MM, Maischein HM, Dufourcq P, Charpentier M, Blader P, Stainier DY. Pitx2c orchestrates embryonic axis extension via mesendodermal cell migration. Elife. 2018 Jun 28;7. pii: e34880. doi: 10.7554/eLife.34880.

Synergistic interaction of sprouting and intussusceptive angiogenesis during zebrafish caudal vein plexus development

Authors:
Karthik S, Djukic T, Kim JD, Zuber B, Makanya A, Odriozola A, Hlushchuk R, Filipovic N, Jin SW, Djonov V
Citation:
Sci Rep. 2018 Jun 29;8(1):9840. doi: 10.1038/s41598-018-27791-6
Epub:
Not Epub
Abstract:
Intussusceptive angiogenesis (IA) is a complementary method to sprouting angiogenesis (SA). The hallmark of IA is formation of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Karthik S, Djukic T, Kim JD, Zuber B, Makanya A, Odriozola A, Hlushchuk R, Filipovic N, Jin SW, Djonov V. Synergistic interaction of sprouting and intussusceptive angiogenesis during zebrafish caudal vein plexus development. Sci Rep. 2018 Jun 29;8(1):9840. doi: 10.1038/s41598-018-27791-6.

CHP1 reduction ameliorates spinal muscular atrophy pathology by restoring calcineurin activity and endocytosis

Authors:
Janzen E, Mendoza-Ferreira N, Hosseinibarkooie S, Schneider S, Hupperich K, Tschanz T, Grysko V, Riessland M, Hammerschmidt M, Rigo F, Bennett CF, Kye MJ, Torres-Benito L, Wirth B
Citation:
Brain. 2018 Jun 28. doi: 10.1093/brain/awy167. [Epub ahead of print]
Epub:
Yes
Abstract:
Autosomal recessive spinal muscular atrophy (SMA), the leading genetic cause of infant lethality, is caused by homozygous loss...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Janzen E, Mendoza-Ferreira N, Hosseinibarkooie S, Schneider S, Hupperich K, Tschanz T, Grysko V, Riessland M, Hammerschmidt M, Rigo F, Bennett CF, Kye MJ, Torres-Benito L, Wirth B. CHP1 reduction ameliorates spinal muscular atrophy pathology by restoring calcineurin activity and endocytosis. Brain. 2018 Jun 28. doi: 10.1093/brain/awy167. [Epub ahead of print].

Apoptosis of Endothelial Cells Contributes to Brain Vessel Pruning of Zebrafish During Development

Authors:
Zhang Y, Xu B, Chen Q, Yan Y, Du J, Du X
Citation:
Front Mol Neurosci. 2018 Jun 28;11:222. doi: 10.3389/fnmol.2018.00222. eCollection 2018
Epub:
Not Epub
Abstract:
During development, immature blood vessel networks remodel to form a simplified and efficient vasculature to meet the demand...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang Y, Xu B, Chen Q, Yan Y, Du J, Du X. Apoptosis of Endothelial Cells Contributes to Brain Vessel Pruning of Zebrafish During Development. Front Mol Neurosci. 2018 Jun 28;11:222. doi: 10.3389/fnmol.2018.00222. eCollection 2018.

An alternative evolutionary pathway for the twin-tail goldfish via szl gene mutation

Authors:
Abe G, Lee SH, Li IJ, Ota KG
Citation:
J Exp Zool B Mol Dev Evol. 2018 Jun;330(4):234-241. doi: 10.1002/jez.b.22811
Epub:
Not Epub
Abstract:
The twin-tail of ornamental goldfish provides unique evolutionary evidence that the highly conserved midline localization of...
Delivery Method:
microinjection
Organism or Cell Type:
Carassius auratus (goldfish)
Citation Extract:
Abe G, Lee SH, Li IJ, Ota KG. An alternative evolutionary pathway for the twin-tail goldfish via szl gene mutation. J Exp Zool B Mol Dev Evol. 2018 Jun;330(4):234-241. doi: 10.1002/jez.b.22811.

Bsx controls pineal complex development

Authors:
Schredelseker T, Driever W
Citation:
Development. 2018 Jul 9;145(13). pii: dev163477. doi: 10.1242/dev.163477
Epub:
Not Epub
Abstract:
Neuroendocrine cells in the pineal gland release melatonin during the night and, in teleosts, are directly photoreceptive....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Schredelseker T, Driever W. Bsx controls pineal complex development. Development. 2018 Jul 9;145(13). pii: dev163477. doi: 10.1242/dev.163477.

Nucleo-cytoplasmic transport of TDP-43 studied in real time: impaired microglia function leads to axonal spreading of TDP-43 in degenerating motor neurons

Authors:
Svahn AJ, Don EK, Badrock AP, Cole NJ, Graeber MB, Yerbury JJ, Chung R, Morsch M
Citation:
Acta Neuropathol. 2018 Jun 25. doi: 10.1007/s00401-018-1875-2. [Epub ahead of print]
Epub:
Yes
Abstract:
Transactivating DNA-binding protein-43 (TDP-43) deposits represent a typical finding in almost all ALS patients, more than half...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Svahn AJ, Don EK, Badrock AP, Cole NJ, Graeber MB, Yerbury JJ, Chung R, Morsch M. Nucleo-cytoplasmic transport of TDP-43 studied in real time: impaired microglia function leads to axonal spreading of TDP-43 in degenerating motor neurons. Acta Neuropathol. 2018 Jun 25. doi: 10.1007/s00401-018-1875-2. [Epub ahead of print].

Shigella-Induced Emergency Granulopoiesis Protects Zebrafish Larvae from Secondary Infection

Authors:
Willis AR, Torraca V, Gomes MC, Shelley J, Mazon-Moya M, Filloux A, Lo Celso C, Mostowy S
Citation:
MBio. 2018 Jun 26;9(3). pii: e00933-18. doi: 10.1128/mBio.00933-18
Epub:
Not Epub
Abstract:
Emergency granulopoiesis is a hematopoietic program of stem cell-driven neutrophil production used to counteract immune cell...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Willis AR, Torraca V, Gomes MC, Shelley J, Mazon-Moya M, Filloux A, Lo Celso C, Mostowy S. Shigella-Induced Emergency Granulopoiesis Protects Zebrafish Larvae from Secondary Infection. MBio. 2018 Jun 26;9(3). pii: e00933-18. doi: 10.1128/mBio.00933-18.

Inhibition of Lysosome Membrane Recycling Causes Accumulation of Gangliosides that Contribute to Neurodegeneration

Authors:
Boutry M, Branchu J, Lustremant C, Pujol C, Pernelle J, Matusiak R, Seyer A, Poirel M, Chu-Van E, Pierga A, Dobrenis K, Puech JP, Caillaud C, Durr A, Brice A, Colsch B, Mochel F, El Hachimi KH, Stevanin G, Darios F
Citation:
Cell Rep. 2018 Jun 26;23(13):3813-3826. doi: 10.1016/j.celrep.2018.05.098
Epub:
Not Epub
Abstract:
Lysosome membrane recycling occurs at the end of the autophagic pathway and requires proteins that are mostly encoded by genes...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Boutry M, Branchu J, Lustremant C, Pujol C, Pernelle J, Matusiak R, Seyer A, Poirel M, Chu-Van E, Pierga A, Dobrenis K, Puech JP, Caillaud C, Durr A, Brice A, Colsch B, Mochel F, El Hachimi KH, Stevanin G, Darios F. Inhibition of Lysosome Membrane Recycling Causes Accumulation of Gangliosides that Contribute to Neurodegeneration. Cell Rep. 2018 Jun 26;23(13):3813-3826. doi: 10.1016/j.celrep.2018.05.098.

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