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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Mutational analysis of dishevelled genes in zebrafish reveals distinct functions in embryonic patterning and gastrulation cell movements

Authors:
Xing YY, Cheng XN, Li YL, Zhang C, Saquet A, Liu YY, Shao M, Shi DL
Citation:
PLoS Genet. 2018 Aug 6;14(8):e1007551. doi: 10.1371/journal.pgen.1007551. eCollection 2018 Aug
Epub:
Not Epub
Abstract:
Wnt signaling plays critical roles in dorsoventral fate specification and anteroposterior patterning, as well as in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xing YY, Cheng XN, Li YL, Zhang C, Saquet A, Liu YY, Shao M, Shi DL. Mutational analysis of dishevelled genes in zebrafish reveals distinct functions in embryonic patterning and gastrulation cell movements. PLoS Genet. 2018 Aug 6;14(8):e1007551. doi: 10.1371/journal.pgen.1007551. eCollection 2018 Aug.

The age-regulated zinc finger factor ZNF367 is a new modulator of neuroblast proliferation during embryonic neurogenesis

Authors:
Naef V, Monticelli S, Corsinovi D, Mazzetto MT, Cellerino A, Ori M
Citation:
Sci Rep. 2018 Aug 7;8(1):11836. doi: 10.1038/s41598-018-30302-2
Epub:
Not Epub
Abstract:
Global population aging is one of the major social and economic challenges of contemporary society. During aging the...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Naef V, Monticelli S, Corsinovi D, Mazzetto MT, Cellerino A, Ori M. The age-regulated zinc finger factor ZNF367 is a new modulator of neuroblast proliferation during embryonic neurogenesis. Sci Rep. 2018 Aug 7;8(1):11836. doi: 10.1038/s41598-018-30302-2.

The mitochondrial transporter SLC25A25 links ciliary TRPP2 signaling and cellular metabolism

Authors:
Hofherr A, Seger C, Fitzpatrick F, Busch T, Michel E, Luan J, Osterried L, Linden F, Kramer-Zucker A, Wakimoto B, Schütze C, Wiedemann N, Artati A, Adamski J, Walz G, Kunji ERS, Montell C, Watnick T, Köttgen M
Citation:
PLoS Biol. 2018 Aug 6;16(8):e2005651. doi: 10.1371/journal.pbio.2005651. eCollection 2018 Aug
Epub:
Not Epub
Abstract:
Cilia are organelles specialized in movement and signal transduction. The ciliary transient receptor potential ion channel...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hofherr A, Seger C, Fitzpatrick F, Busch T, Michel E, Luan J, Osterried L, Linden F, Kramer-Zucker A, Wakimoto B, Schütze C, Wiedemann N, Artati A, Adamski J, Walz G, Kunji ERS, Montell C, Watnick T, Köttgen M. The mitochondrial transporter SLC25A25 links ciliary TRPP2 signaling and cellular metabolism. PLoS Biol. 2018 Aug 6;16(8):e2005651. doi: 10.1371/journal.pbio.2005651. eCollection 2018 Aug.

Body Cavity Development Is Guided by Morphogen Transfer between Germ Layers

Authors:
Schlueter J, Mikawa T
Citation:
Cell Rep. 2018 Aug 7;24(6):1456-1463. doi: 10.1016/j.celrep.2018.07.015
Epub:
Not Epub
Abstract:
The body cavity is a space where internal organs develop and are placed. Despite the importance of this internal space, how the...
Delivery Method:
microinjection
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Schlueter J, Mikawa T. Body Cavity Development Is Guided by Morphogen Transfer between Germ Layers. Cell Rep. 2018 Aug 7;24(6):1456-1463. doi: 10.1016/j.celrep.2018.07.015.

Microinjection of DNA Constructs into Xenopus Embryos for Gene Misexpression and cis-Regulatory Module Analysis

Authors:
Yasuoka Y, Taira M
Citation:
Cold Spring Harb Protoc. 2018 Aug 21. doi: 10.1101/pdb.prot097279. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Introducing exogenous DNA into an embryo can promote misexpression of a gene of interest via transcription regulated by an...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Yasuoka Y, Taira M. Microinjection of DNA Constructs into Xenopus Embryos for Gene Misexpression and cis-Regulatory Module Analysis. Cold Spring Harb Protoc. 2018 Aug 21. doi: 10.1101/pdb.prot097279. [Epub ahead of print].

Deep learning image recognition enables efficient genome editing in zebrafish by automated injections

Authors:
Cordero-Maldonado ML, Perathoner S, van der Kolk K-J, Boland R, Heins-Marroquin U, Spaink HP, Meijer AH, Crawford AD, de Sonneville J
Citation:
PLoS One. 2019 Jan 7;14(1):e0202377. doi: 10.1371/journal.pone.0202377. eCollection 2019.
Epub:
Not Epub
Abstract:
One of the most popular techniques in zebrafish research is microinjection. This is a rapid and efficient way to genetically...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cordero-Maldonado ML, Perathoner S, van der Kolk K-J, Boland R, Heins-Marroquin U, Spaink HP, Meijer AH, Crawford AD, de Sonneville J. Deep learning image recognition enables efficient genome editing in zebrafish by automated injections. PLoS One. 2019 Jan 7;14(1):e0202377. doi: 10.1371/journal.pone.0202377. eCollection 2019..

Hyperinsulinemia induces insulin resistance and immune suppression via Ptpn6/Shp1 in zebrafish

Authors:
Marín-Juez R, Jong-Raadsen S, Yang S, Spaink HP
Citation:
J Endocrinol. 2014 Aug;222(2):229-41. doi: 10.1530/JOE-14-0178. Epub 2014 Jun 5
Epub:
Not Epub
Abstract:
Type 2 diabetes, obesity, and metabolic syndrome are pathologies where insulin resistance plays a central role, and that affect...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Marín-Juez R, Jong-Raadsen S, Yang S, Spaink HP. Hyperinsulinemia induces insulin resistance and immune suppression via Ptpn6/Shp1 in zebrafish. J Endocrinol. 2014 Aug;222(2):229-41. doi: 10.1530/JOE-14-0178. Epub 2014 Jun 5.

Macrophages inhibit Aspergillus fumigatus germination and neutrophil-mediated fungal killing

Authors:
Rosowski EE, Raffa N, Knox BP, Golenberg N, Keller NP, Huttenlocher A
Citation:
PLoS Pathog. 2018 Aug 2;14(8):e1007229. doi: 10.1371/journal.ppat.1007229. eCollection 2018 Aug
Epub:
Not Epub
Abstract:
In immunocompromised individuals, Aspergillus fumigatus causes invasive fungal disease that is often difficult to treat....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rosowski EE, Raffa N, Knox BP, Golenberg N, Keller NP, Huttenlocher A. Macrophages inhibit Aspergillus fumigatus germination and neutrophil-mediated fungal killing. PLoS Pathog. 2018 Aug 2;14(8):e1007229. doi: 10.1371/journal.ppat.1007229. eCollection 2018 Aug.

De Novo Mutations of CCNK Cause a Syndromic Neurodevelopmental Disorder with Distinctive Facial Dysmorphism

Authors:
Fan Y, Yin W, Hu B, Kline AD, Zhang VW, Liang D, Sun Y, Wang L, Tang S, Powis Z, Li L, Yan H, Shi Z, Yang X, Chen Y, Wang J, Jiang Y, Tan H, Gu X, Wu L, Yu Y
Citation:
Am J Hum Genet. 2018 Aug 6. pii: S0002-9297(18)30246-5. doi: 10.1016/j.ajhg.2018.07.019. [Epub ahead of print]
Epub:
Yes
Abstract:
Neurodevelopment is a transcriptionally orchestrated process. Cyclin K, a regulator of transcription encoded by CCNK, is...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fan Y, Yin W, Hu B, Kline AD, Zhang VW, Liang D, Sun Y, Wang L, Tang S, Powis Z, Li L, Yan H, Shi Z, Yang X, Chen Y, Wang J, Jiang Y, Tan H, Gu X, Wu L, Yu Y. De Novo Mutations of CCNK Cause a Syndromic Neurodevelopmental Disorder with Distinctive Facial Dysmorphism. Am J Hum Genet. 2018 Aug 6. pii: S0002-9297(18)30246-5. doi: 10.1016/j.ajhg.2018.07.019. [Epub ahead of print].

Wnt/PCP controls spreading of Wnt/β-catenin signals by cytonemes in vertebrates

Authors:
Mattes B, Dang Y, Greicius G, Kaufmann LT, Prunsche B, Rosenbauer J, Stegmaier J, Mikut R, Özbek S, Nienhaus GU, Schug A, Virshup DM, Scholpp S
Citation:
Elife. 2018 Jul 31;7. pii: e36953. doi: 10.7554/eLife.36953
Epub:
Not Epub
Abstract:
Signaling filopodia, termed cytonemes, are dynamic actin-based membrane structures that regulate the exchange of signaling...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mattes B, Dang Y, Greicius G, Kaufmann LT, Prunsche B, Rosenbauer J, Stegmaier J, Mikut R, Özbek S, Nienhaus GU, Schug A, Virshup DM, Scholpp S. Wnt/PCP controls spreading of Wnt/β-catenin signals by cytonemes in vertebrates. Elife. 2018 Jul 31;7. pii: e36953. doi: 10.7554/eLife.36953.

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