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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Pressure-Modulated Selective Electrokinetic Trapping for Direct Enrichment, Purification, and Detection of Nucleic Acids in Human Serum

Authors:
Ouyang W, Li Z, Han J
Citation:
Anal Chem. 2018 Aug 29. doi: 10.1021/acs.analchem.8b02330. [Epub ahead of print]
Epub:
Yes
Abstract:
Micro total analysis systems (μTAS) have been extensively developed for the detection of nucleic acids (NAs) in resource-...
Citation Extract:
Ouyang W, Li Z, Han J. Pressure-Modulated Selective Electrokinetic Trapping for Direct Enrichment, Purification, and Detection of Nucleic Acids in Human Serum. Anal Chem. 2018 Aug 29. doi: 10.1021/acs.analchem.8b02330. [Epub ahead of print].

Mutation in the intracellular chloride channel CLCC1 associated with autosomal recessive retinitis pigmentosa

Authors:
Li L, Jiao X, D’Atri I, Ono F, Nelson R, Chan C-C, Nakaya N, Ma Z, Ma Y, Cai X, Zhang L, Lin S, Hameed A, Chioza BA, Hardy H, Arno G, Hull S, Khan MI, Fasham J, Harlalka GV, Michaelides M, Moore AT, Akdemir ZHC, Jhangiani S, Lupski JR, Cremers FPM, Qamar R, Salman A, Chilton J, Self J, Ayyagari R, Firoz Kabir F, Naeem MA, Ali M, Akram J, Sieving PA, Riazuddin S, Baple EL, Riazuddin SA, Crosby AH, Hejtmancik JF
Citation:
PLoS Genet. 2018;14(8):e1007504. doi:10.1371/journal.pgen.1007504
Epub:
Not Epub
Abstract:
We identified a homozygous missense alteration (c.75C>A, p.D25E) in CLCC1, encoding a presumptive intracellular chloride...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li L, Jiao X, D’Atri I, Ono F, Nelson R, Chan C-C, Nakaya N, Ma Z, Ma Y, Cai X, Zhang L, Lin S, Hameed A, Chioza BA, Hardy H, Arno G, Hull S, Khan MI, Fasham J, Harlalka GV, Michaelides M, Moore AT, Akdemir ZHC, Jhangiani S, Lupski JR, Cremers FPM, Qamar R, Salman A, Chilton J, Self J, Ayyagari R, Firoz Kabir F, Naeem MA, Ali M, Akram J, Sieving PA, Riazuddin S, Baple EL, Riazuddin SA, Crosby AH, Hejtmancik JF. Mutation in the intracellular chloride channel CLCC1 associated with autosomal recessive retinitis pigmentosa. PLoS Genet. 2018;14(8):e1007504. doi:10.1371/journal.pgen.1007504.

TBC1d24-ephrinB2 interaction regulates contact inhibition of locomotion in neural crest cell migration

Authors:
Yoon J, Hwang Y-S, Lee M, Sun J, Cho HJ, Knapik L, Daar IO
Citation:
Nat Comm. 2018;9:3491. doi:10.1038/s41467-018-05924-9
Epub:
Not Epub
Abstract:
Although Eph-ephrin signalling has been implicated in the migration of cranial neural crest (CNC) cells, it is still unclear...
Organism or Cell Type:
Xenopus
Citation Extract:
Yoon J, Hwang Y-S, Lee M, Sun J, Cho HJ, Knapik L, Daar IO. TBC1d24-ephrinB2 interaction regulates contact inhibition of locomotion in neural crest cell migration. Nat Comm. 2018;9:3491. doi:10.1038/s41467-018-05924-9.

Widespread intronic polyadenylation inactivates tumour suppressor genes in leukaemia

Authors:
Lee S-H, Singh I, Tisdale S, Abdel-Wahab O, Leslie CS, Mayr C
Citation:
Nature. 2018:[Epub ahead of print] doi:10.1038/s41586-018-0465-8DO
Epub:
Yes
Abstract:
DNA mutations are known cancer drivers. Here we investigated whether mRNA events that are upregulated in cancer can...
Organism or Cell Type:
cell culture: HeLa
Citation Extract:
Lee S-H, Singh I, Tisdale S, Abdel-Wahab O, Leslie CS, Mayr C. Widespread intronic polyadenylation inactivates tumour suppressor genes in leukaemia. Nature. 2018:[Epub ahead of print] doi:10.1038/s41586-018-0465-8DO.

De Novo Mutations Activating Germline TP53 in an Inherited Bone-Marrow-Failure Syndrome

Authors:
Toki T, Yoshida K, Wang R, Nakamura S, Maekawa T, Goi K, Katoh MC, Mizuno S, Sugiyama F, Kanezaki R, Uechi T, Nakajima Y, Sato Y, Okuno Y, Sato-Otsubo A, Shiozawa Y, Kataoka K, Shiraishi Y, Sanada M, Chiba K, Tanaka H, Terui K, Sato T, Kamio T, Sakaguchi H, Ohga S, Kuramitsu M, Hamaguchi I, Ohara A, Kanno H, Miyano S, Kojima S, Ishiguro A, Sugita K, Kenmochi N, Takahashi S, Eto K, Ogawa S, Ito E
Citation:
Am J Hum Genet. 2018 Aug 22. pii: S0002-9297(18)30247-7. doi: 10.1016/j.ajhg.2018.07.020. [Epub ahead of print]
Epub:
Yes
Abstract:
Inherited bone-marrow-failure syndromes (IBMFSs) include heterogeneous genetic disorders characterized by bone-marrow failure,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Toki T, Yoshida K, Wang R, Nakamura S, Maekawa T, Goi K, Katoh MC, Mizuno S, Sugiyama F, Kanezaki R, Uechi T, Nakajima Y, Sato Y, Okuno Y, Sato-Otsubo A, Shiozawa Y, Kataoka K, Shiraishi Y, Sanada M, Chiba K, Tanaka H, Terui K, Sato T, Kamio T, Sakaguchi H, Ohga S, Kuramitsu M, Hamaguchi I, Ohara A, Kanno H, Miyano S, Kojima S, Ishiguro A, Sugita K, Kenmochi N, Takahashi S, Eto K, Ogawa S, Ito E. De Novo Mutations Activating Germline TP53 in an Inherited Bone-Marrow-Failure Syndrome. Am J Hum Genet. 2018 Aug 22. pii: S0002-9297(18)30247-7. doi: 10.1016/j.ajhg.2018.07.020. [Epub ahead of print].

Vertebrate myosin 1d regulates left-right organizer morphogenesis and laterality

Authors:
Saydmohammed M, Yagi H, Calderon M, Clark MJ, Feinstein T, Sun M, Stolz DB, Watkins SC, Amack JD, Lo CW, Tsang M
Citation:
Nat Commun. 2018 Aug 23;9(1):3381. doi: 10.1038/s41467-018-05866-2
Epub:
Not Epub
Abstract:
Establishing left-right asymmetry is a fundamental process essential for arrangement of visceral organs during development. In...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Saydmohammed M, Yagi H, Calderon M, Clark MJ, Feinstein T, Sun M, Stolz DB, Watkins SC, Amack JD, Lo CW, Tsang M. Vertebrate myosin 1d regulates left-right organizer morphogenesis and laterality. Nat Commun. 2018 Aug 23;9(1):3381. doi: 10.1038/s41467-018-05866-2.

A transition from SoxB1 to SoxE transcription factors is essential for progression from pluripotent blastula cells to neural crest cells

Authors:
Buitrago-Delgado E, Schock EN, Nordin K, LaBonne C
Citation:
Dev Biol. 2018 Aug 22. pii: S0012-1606(18)30259-8. doi: 10.1016/j.ydbio.2018.08.008. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The neural crest is a stem cell population unique to vertebrate embryos that gives rise to derivatives from multiple embryonic...
Organism or Cell Type:
Xenopus
Citation Extract:
Buitrago-Delgado E, Schock EN, Nordin K, LaBonne C. A transition from SoxB1 to SoxE transcription factors is essential for progression from pluripotent blastula cells to neural crest cells. Dev Biol. 2018 Aug 22. pii: S0012-1606(18)30259-8. doi: 10.1016/j.ydbio.2018.08.008. [Epub ahead of print].

Anisotropic organization of circumferential actomyosin characterizes hematopoietic stem cells emergence in the zebrafish

Authors:
Lancino M, Majello S, Herbert S, De Chaumont F, Tinevez JY, Olivo-Marin JC, Herbomel P, Schmidt A
Citation:
Elife. 2018 Aug 22;7. pii: e37355. doi: 10.7554/eLife.37355
Epub:
Not Epub
Abstract:
Hematopoiesis leads to the formation of blood and immune cells. Hematopoietic stem cells emerge during development, from...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lancino M, Majello S, Herbert S, De Chaumont F, Tinevez JY, Olivo-Marin JC, Herbomel P, Schmidt A. Anisotropic organization of circumferential actomyosin characterizes hematopoietic stem cells emergence in the zebrafish. Elife. 2018 Aug 22;7. pii: e37355. doi: 10.7554/eLife.37355.

Characterization of an NLRP1 Inflammasome from Zebrafish Reveals a Unique Sequential Activation Mechanism Underlying Inflammatory Caspases in Ancient Vertebrates

Authors:
Li JY, Gao K, Shao T, Fan DD, Hu CB, Sun CC, Dong WR, Lin AF, Xiang LX, Shao JZ
Citation:
J Immunol. 2018 Aug 27. pii: ji1800498. doi: 10.4049/jimmunol.1800498. [Epub ahead of print]
Epub:
Yes
Abstract:
NLRP1 inflammasome is one of the best-characterized inflammasomes in humans and other mammals. However, the existence of this...
Organism or Cell Type:
zebrafish
Citation Extract:
Li JY, Gao K, Shao T, Fan DD, Hu CB, Sun CC, Dong WR, Lin AF, Xiang LX, Shao JZ. Characterization of an NLRP1 Inflammasome from Zebrafish Reveals a Unique Sequential Activation Mechanism Underlying Inflammatory Caspases in Ancient Vertebrates. J Immunol. 2018 Aug 27. pii: ji1800498. doi: 10.4049/jimmunol.1800498. [Epub ahead of print].

Polarized cortical tension drives zebrafish epiboly movements

Authors:
Hernández-Vega A, Marsal M, Pouille PA, Tosi S, Colombelli J, Luque T, Navajas D, Pagonabarraga I, Martín-Blanco E
Citation:
EMBO J. 2017 Jan 4;36(1):25-41. doi: 10.15252/embj.201694264. Epub 2016 Nov 9
Epub:
Not Epub
Abstract:
The principles underlying the biomechanics of morphogenesis are largely unknown. Epiboly is an essential embryonic event in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hernández-Vega A, Marsal M, Pouille PA, Tosi S, Colombelli J, Luque T, Navajas D, Pagonabarraga I, Martín-Blanco E. Polarized cortical tension drives zebrafish epiboly movements. EMBO J. 2017 Jan 4;36(1):25-41. doi: 10.15252/embj.201694264. Epub 2016 Nov 9.

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