You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

A gene regulatory network underlying the formation of pre-placodal ectoderm in Xenopus laevis

Authors:
Maharana SK, Schlosser G
Citation:
BMC Biol. 2018 Jul 16;16(1):79. doi: 10.1186/s12915-018-0540-5
Epub:
Not Epub
Abstract:
BACKGROUND: The neural plate border ectoderm gives rise to key developmental structures during embryogenesis, including the...
Link:
https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-018-0540-5
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Maharana SK, Schlosser G. A gene regulatory network underlying the formation of pre-placodal ectoderm in Xenopus laevis. BMC Biol. 2018 Jul 16;16(1):79. doi: 10.1186/s12915-018-0540-5.

Elesclomol restores mitochondrial function in genetic models of copper deficiency

Authors:
Soma S, Latimer AJ, Chun H, Vicary AC, Timbalia SA, Boulet A, Rahn JJ, Chan SSL, Leary SC, Kim BE, Gitlin JD, Gohil VM
Citation:
Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8161-8166. doi: 10.1073/pnas.1806296115. Epub 2018 Jul 23
Epub:
Not Epub
Abstract:
Copper is an essential cofactor of cytochrome c oxidase (CcO), the terminal enzyme of the mitochondrial respiratory chain....
Link:
http://www.pnas.org/content/pnas/early/2018/07/17/1806296115.full.pdf
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Soma S, Latimer AJ, Chun H, Vicary AC, Timbalia SA, Boulet A, Rahn JJ, Chan SSL, Leary SC, Kim BE, Gitlin JD, Gohil VM. Elesclomol restores mitochondrial function in genetic models of copper deficiency. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8161-8166. doi: 10.1073/pnas.1806296115. Epub 2018 Jul 23.

The atypical Rho GTPase, RhoU, regulates cell-adhesion molecules during cardiac morphogenesis

Authors:
Dickover M, Hegarty JM, Ly K, Lopez D, Yang H, Zhang R, Tedeschi N, Hsiai TK, Chi NC
Citation:
Dev Biol. 2014 May 15;389(2):182-91. doi: 10.1016/j.ydbio.2014.02.014. Epub 2014 Mar 7
Epub:
Not Epub
Abstract:
The vertebrate heart undergoes early complex morphologic events in order to develop key cardiac structures that regulate its...
Link:
https://www.sciencedirect.com/science/article/pii/S0012160614000943
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dickover M, Hegarty JM, Ly K, Lopez D, Yang H, Zhang R, Tedeschi N, Hsiai TK, Chi NC. The atypical Rho GTPase, RhoU, regulates cell-adhesion molecules during cardiac morphogenesis. Dev Biol. 2014 May 15;389(2):182-91. doi: 10.1016/j.ydbio.2014.02.014. Epub 2014 Mar 7.

Cerebral Cavernous Malformation 1/2 complex controls ROCK1 and ROCK2 complementary functions for endothelial integrity

Authors:
Lisowska J, Rödel CJ, Manet S, Miroshnikova YA, Boyault C, Planus E, De Mets R, Lee H-H, Destaing O, Mertani H, Boulday G, Tournier-Lasserve E, Balland M, Abdelilah-Seyfried S, Albiges-Rizo C, Faurobert E.
Citation:
J Cell Sci. 2018;[Epub] doi:10.1242/jcs.216093
Epub:
Yes
Abstract:
Endothelial integrity relies on a mechanical crosstalk between intercellular and cell-matrix interactions. This cross-talk is...
Link:
http://jcs.biologists.org/content/early/2018/07/19/jcs.216093
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lisowska J, Rödel CJ, Manet S, Miroshnikova YA, Boyault C, Planus E, De Mets R, Lee H-H, Destaing O, Mertani H, Boulday G, Tournier-Lasserve E, Balland M, Abdelilah-Seyfried S, Albiges-Rizo C, Faurobert E. . Cerebral Cavernous Malformation 1/2 complex controls ROCK1 and ROCK2 complementary functions for endothelial integrity. J Cell Sci. 2018;[Epub] doi:10.1242/jcs.216093.

Enhanced expression of MycN/CIP2A drives neural crest toward a neural stem cell-like fate: Implications for priming of neuroblastoma

Authors:
Kerosuo L, Neppala P, Hsin J, Mohlin S, Vieceli FM, Török Z, Laine A, Westermarck J, Bronner ME
Citation:
Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):E7351-E7360. doi: 10.1073/pnas.1800039115. Epub 2018 Jul 18
Epub:
Not Epub
Abstract:
Neuroblastoma is a neural crest-derived childhood tumor of the peripheral nervous system in which MycN amplification is a...
Link:
http://www.pnas.org/content/early/2018/07/17/1800039115
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Kerosuo L, Neppala P, Hsin J, Mohlin S, Vieceli FM, Török Z, Laine A, Westermarck J, Bronner ME. Enhanced expression of MycN/CIP2A drives neural crest toward a neural stem cell-like fate: Implications for priming of neuroblastoma. Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):E7351-E7360. doi: 10.1073/pnas.1800039115. Epub 2018 Jul 18.

Neutrophils use superoxide to control bacterial infection at a distance

Authors:
Phan QT, Sipka T, Gonzalez C, Levraud JP, Lutfalla G, Nguyen-Chi M
Citation:
PLoS Pathog. 2018 Jul 17;14(7):e1007157. doi: 10.1371/journal.ppat.1007157. eCollection 2018 Jul
Epub:
Not Epub
Abstract:
Understanding the roles of neutrophils and macrophages in fighting bacterial infections is a critical issue in human...
Link:
http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1007157
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Phan QT, Sipka T, Gonzalez C, Levraud JP, Lutfalla G, Nguyen-Chi M. Neutrophils use superoxide to control bacterial infection at a distance. PLoS Pathog. 2018 Jul 17;14(7):e1007157. doi: 10.1371/journal.ppat.1007157. eCollection 2018 Jul.

CERKL interacts with mitochondrial TRX2 and protects retinal cells from oxidative stress-induced apoptosis

Authors:
Li C, Wang L, Zhang J, Huang M, Wong F, Liu X, Liu F, Cui X, Yang G, Chen J, Liu Y, Wang J, Liao S, Gao M, Hu X, Shu X, Wang Q, Yin Z, Tang Z, Liu M
Citation:
Biochim Biophys Acta. 2014 Jul;1842(7):1121-9. doi: 10.1016/j.bbadis.2014.04.009. Epub 2014 Apr 13
Epub:
Not Epub
Abstract:
Mutations in the ceramide kinase-like gene (CERKL) are associated with severe retinal degeneration. However, the exact function...
Link:
https://core.ac.uk/download/pdf/82298513.pdf
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li C, Wang L, Zhang J, Huang M, Wong F, Liu X, Liu F, Cui X, Yang G, Chen J, Liu Y, Wang J, Liao S, Gao M, Hu X, Shu X, Wang Q, Yin Z, Tang Z, Liu M. CERKL interacts with mitochondrial TRX2 and protects retinal cells from oxidative stress-induced apoptosis. Biochim Biophys Acta. 2014 Jul;1842(7):1121-9. doi: 10.1016/j.bbadis.2014.04.009. Epub 2014 Apr 13.

Glycine Promotes the Survival of a Subpopulation of Neural Stem Cells

Authors:
Bekri A, Drapeau P
Citation:
Front Cell Dev Biol. 2018 Jul 11;6:68. doi: 10.3389/fcell.2018.00068. eCollection 2018
Epub:
Not Epub
Abstract:
Glycine is mainly known as an inhibitory neurotransmitter in adult mature neurons, regulating neuronal network activity in the...
Link:
https://www.frontiersin.org/articles/10.3389/fcell.2018.00068/full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bekri A, Drapeau P. Glycine Promotes the Survival of a Subpopulation of Neural Stem Cells. Front Cell Dev Biol. 2018 Jul 11;6:68. doi: 10.3389/fcell.2018.00068. eCollection 2018.

A cell cycle-coordinated nuclear compartment for Polymerase II transcription encompasses the earliest gene expression before global genome activation

Authors:
Hadzhiev Y, Qureshi H, Wheatley L, Cooper L, Jasiulewicz A, Nguyen HV, Wragg J, Poovathumkadavil D, Conic S, Bajan S, Sik A, Hutvagner G, Tora L, Gambus A, Fossey JS, Mueller F
Citation:
BioRXive. 2018;[Epub] doi:doi.org/10.1101/366468
Epub:
Not Epub
Abstract:
Most metazoan embryos commence development with rapid cleavages without zygotic gene expression and their genome activation is...
Link:
https://www.biorxiv.org/content/early/2018/07/15/366468
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hadzhiev Y, Qureshi H, Wheatley L, Cooper L, Jasiulewicz A, Nguyen HV, Wragg J, Poovathumkadavil D, Conic S, Bajan S, Sik A, Hutvagner G, Tora L, Gambus A, Fossey JS, Mueller F. A cell cycle-coordinated nuclear compartment for Polymerase II transcription encompasses the earliest gene expression before global genome activation. BioRXive. 2018;[Epub] doi:doi.org/10.1101/366468.

Spatial and temporal variations in hemodynamic forces initiate cardiac trabeculation

Authors:
Lee J, Vedula V, Baek KI, Chen J, Hsu JJ, Ding Y, Chang CC, Kang H, Small A, Fei P, Chuong CM, Li R, Demer L, Packard RRS, Marsden AL, Hsiai TK
Citation:
JCI Insight. 2018 Jul 12;3(13). pii: 96672. doi: 10.1172/jci.insight.96672. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Hemodynamic shear force has been implicated as modulating Notch signaling-mediated cardiac trabeculation. Whether the...
Link:
https://insight.jci.org/articles/view/96672
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lee J, Vedula V, Baek KI, Chen J, Hsu JJ, Ding Y, Chang CC, Kang H, Small A, Fei P, Chuong CM, Li R, Demer L, Packard RRS, Marsden AL, Hsiai TK. Spatial and temporal variations in hemodynamic forces initiate cardiac trabeculation. JCI Insight. 2018 Jul 12;3(13). pii: 96672. doi: 10.1172/jci.insight.96672. [Epub ahead of print].

Pages