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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

The role of internal convection in respiratory gas transfer and aerobic metabolism in larval zebrafish ( Danio rerio)

Authors:
Hughes MC, Zimmer AM, Perry SF
Citation:
Am J Physiol Regul Integr Comp Physiol. 2019 Jan 2. doi: 10.1152/ajpregu.00315.2018. [Epub ahead of print]
Epub:
Yes
Abstract:
Purely diffusive O2 transport typically is insufficient to sustain aerobic metabolism in most multicellular organisms. In...
Link:
https://www.physiology.org/doi/abs/10.1152/ajpregu.00315.2018
Organism or Cell Type:
zebrafish
Citation Extract:
Hughes MC, Zimmer AM, Perry SF. The role of internal convection in respiratory gas transfer and aerobic metabolism in larval zebrafish ( Danio rerio). Am J Physiol Regul Integr Comp Physiol. 2019 Jan 2. doi: 10.1152/ajpregu.00315.2018. [Epub ahead of print].

Morpholino Oligonucleotide Crosslinked Hydrogels as Portable Optical Oligonucleotide Biosensors

Authors:
Langford G, Raeburn J, Ferrier DC, Hands PJW, Shaver MP
Citation:
ACS Sens. 2018 Dec 28. doi: 10.1021/acssensors.8b01208. [Epub ahead of print]
Epub:
Yes
Abstract:
Morpholino Oligonucleotides (MOs), an uncharged DNA analogue, are functionalized with an acrylamide moiety and incorporated...
Link:
https://pubs.acs.org/doi/10.1021/acssensors.8b01208
Citation Extract:
Langford G, Raeburn J, Ferrier DC, Hands PJW, Shaver MP. Morpholino Oligonucleotide Crosslinked Hydrogels as Portable Optical Oligonucleotide Biosensors. ACS Sens. 2018 Dec 28. doi: 10.1021/acssensors.8b01208. [Epub ahead of print].

Noncanonical Modulation of the eIF2 Pathway Controls an Increase in Local Translation during Neural Wiring

Authors:
Cagnetta R, Wong HH-W, Frese CK, Mallucci GR, Krijgsveld J, Holt CE
Citation:
Molec Cell. 2018;[Epub] doi:doi.org/10.1016/j.molcel.2018.11.013
Epub:
Yes
Abstract:
Local translation is rapidly regulated by extrinsic signals during neural wiring, but its control mechanisms remain elusive....
Link:
https://www.cell.com/molecular-cell/fulltext/S1097-2765(18)30983-3
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Cagnetta R, Wong HH-W, Frese CK, Mallucci GR, Krijgsveld J, Holt CE. Noncanonical Modulation of the eIF2 Pathway Controls an Increase in Local Translation during Neural Wiring. Molec Cell. 2018;[Epub] doi:doi.org/10.1016/j.molcel.2018.11.013.

Rho Guanine Nucleotide Exchange Factor ARHGEF17 Is a Risk Gene for Intracranial Aneurysms

Authors:
Yang X, Li J, Fang Y, Zhang Z, Jin D, Chen X, Zhao Y, Li M, Huan L, Kent TA, Dong JF, Jiang R, Yang S, Jin L, Zhang J, Zhong TP, Yu F
Citation:
Circ Genom Precis Med. 2018 Jul;11(7):e002099. doi: 10.1161/CIRCGEN.117.002099
Epub:
Not Epub
Abstract:
BACKGROUND: Intracranial aneurysm (IA) is usually a late-onset disease, affecting 1% to 3% of the general population and...
Link:
https://www.ahajournals.org/doi/10.1161/CIRCGEN.117.002099
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yang X, Li J, Fang Y, Zhang Z, Jin D, Chen X, Zhao Y, Li M, Huan L, Kent TA, Dong JF, Jiang R, Yang S, Jin L, Zhang J, Zhong TP, Yu F. Rho Guanine Nucleotide Exchange Factor ARHGEF17 Is a Risk Gene for Intracranial Aneurysms. Circ Genom Precis Med. 2018 Jul;11(7):e002099. doi: 10.1161/CIRCGEN.117.002099.

PCP-dependent transcellular regulation of actomyosin oscillation facilitates convergent extension of vertebrate tissue

Authors:
Shindo A, Inoue Y, Kinoshita M, Wallingford JB
Citation:
Dev Biol. 2018 Dec 20. pii: S0012-1606(18)30690-0. doi: 10.1016/j.ydbio.2018.12.017. [Epub ahead of print]
Epub:
Yes
Abstract:
Oscillatory flows of actomyosin play a key role in the migration of single cells in culture and in collective cell movements in...
Link:
https://www.sciencedirect.com/science/article/pii/S0012160618306900
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Shindo A, Inoue Y, Kinoshita M, Wallingford JB. PCP-dependent transcellular regulation of actomyosin oscillation facilitates convergent extension of vertebrate tissue. Dev Biol. 2018 Dec 20. pii: S0012-1606(18)30690-0. doi: 10.1016/j.ydbio.2018.12.017. [Epub ahead of print].

Homeogene emx1 is required for nephron distal segment development in zebrafish

Authors:
Morales EE, Handa N, Drummond BE, Chambers JM, Marra AN, Addiego A, Wingert RA
Citation:
Sci Rep. 2018 Dec 21;8(1):18038. doi: 10.1038/s41598-018-36061-4
Epub:
Not Epub
Abstract:
Vertebrate kidneys contain nephron functional units where specialized epithelial cell types are organized into segments with...
Link:
https://www.nature.com/articles/s41598-018-36061-4
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Morales EE, Handa N, Drummond BE, Chambers JM, Marra AN, Addiego A, Wingert RA. Homeogene emx1 is required for nephron distal segment development in zebrafish. Sci Rep. 2018 Dec 21;8(1):18038. doi: 10.1038/s41598-018-36061-4.

Sialic acid catabolism by N-acetylneuraminate pyruvate lyase is essential for muscle function

Authors:
Wen XY, Tarailo-Graovac M, Brand-Arzamendi K, Willems A, Rakic B, Huijben K, Da Silva A, Pan X, El-Rass S, Ng R, Selby K, Philip AM, Yun J, Ye XC, Ross CJ, Lehman AM, Zijlstra F, Bakar AA, Drögemöller B, Moreland J, Wasserman WW, Vallance H, van Scherpenzeel M, Karbassi F, Hoskings M, Engelke U, de Brouwer A, Wevers RA, Pshezhetsky AV, van Karnebeek CD, Lefeber DJ
Citation:
JCI Insight. 2018 Dec 20;3(24). pii: 122373. doi: 10.1172/jci.insight.122373. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Sialic acids are important components of glycoproteins and glycolipids essential for cellular communication, infection, and...
Link:
https://insight.jci.org/articles/view/122373
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wen XY, Tarailo-Graovac M, Brand-Arzamendi K, Willems A, Rakic B, Huijben K, Da Silva A, Pan X, El-Rass S, Ng R, Selby K, Philip AM, Yun J, Ye XC, Ross CJ, Lehman AM, Zijlstra F, Bakar AA, Drögemöller B, Moreland J, Wasserman WW, Vallance H, van Scherpenzeel M, Karbassi F, Hoskings M, Engelke U, de Brouwer A, Wevers RA, Pshezhetsky AV, van Karnebeek CD, Lefeber DJ. Sialic acid catabolism by N-acetylneuraminate pyruvate lyase is essential for muscle function. JCI Insight. 2018 Dec 20;3(24). pii: 122373. doi: 10.1172/jci.insight.122373. [Epub ahead of print].

CD47 Expression in Natural Killer Cells Regulates Homeostasis and Modulates Immune Response to Lymphocytic Choriomeningitis Virus

Authors:
Nath PR, Gangaplara A, Pal-Nath D, Mandal A, Maric D, Sipes JM, Cam M, Shevach EM, Roberts DD
Citation:
Front Immunol. 2018;9:2985. doi:10.3389/fimmu.2018.02985
Epub:
Not Epub
Abstract:
CD47 is a ubiquitous cell surface receptor that directly regulates T cell immunity by interacting with its inhibitory ligand...
Link:
https://www.frontiersin.org/articles/10.3389/fimmu.2018.02985/full
Delivery Method:
i.p. injection
Organism or Cell Type:
mice
Citation Extract:
Nath PR, Gangaplara A, Pal-Nath D, Mandal A, Maric D, Sipes JM, Cam M, Shevach EM, Roberts DD. CD47 Expression in Natural Killer Cells Regulates Homeostasis and Modulates Immune Response to Lymphocytic Choriomeningitis Virus. Front Immunol. 2018;9:2985. doi:10.3389/fimmu.2018.02985.

Biallelic mutations in USP45, encoding a deubiquitinating enzyme, are associated with Leber congenital amaurosis

Authors:
Yi Z, Ouyang J, Sun W, Xiao X, Li S, Jia X, Wang P, Zhang Q
Citation:
J Med Genet. 2018 Dec 20. pii: jmedgenet-2018-105709. doi: 10.1136/jmedgenet-2018-105709. [Epub ahead of print]
Epub:
Yes
Abstract:
Background: Leber congenital amaurosis (LCA) is the earliest and most severe form of inherited retinal dystrophies. In...
Link:
https://jmg.bmj.com/content/early/2018/12/20/jmedgenet-2018-105709
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yi Z, Ouyang J, Sun W, Xiao X, Li S, Jia X, Wang P, Zhang Q. Biallelic mutations in USP45, encoding a deubiquitinating enzyme, are associated with Leber congenital amaurosis. J Med Genet. 2018 Dec 20. pii: jmedgenet-2018-105709. doi: 10.1136/jmedgenet-2018-105709. [Epub ahead of print].

Granulin 1 Promotes Retinal Regeneration in Zebrafish

Authors:
Tsuruma K, Saito Y, Okuyoshi H, Yamaguchi A, Shimazawa M, Goldman D, Hara H
Citation:
Invest Ophthalmol Vis Sci. 2018 Dec 3;59(15):6057-6066. doi: 10.1167/iovs.18-24828
Epub:
Not Epub
Abstract:
Purpose: Retinal degenerative diseases can progress to severe reductions of vision. In general, the changes are permanent in...
Link:
https://iovs.arvojournals.org/article.aspx?articleid=2719508
Delivery Method:
electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Tsuruma K, Saito Y, Okuyoshi H, Yamaguchi A, Shimazawa M, Goldman D, Hara H. Granulin 1 Promotes Retinal Regeneration in Zebrafish. Invest Ophthalmol Vis Sci. 2018 Dec 3;59(15):6057-6066. doi: 10.1167/iovs.18-24828.

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