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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Inhibition of dengue virus replication in monocyte-derived dendritic cells by vivo-morpholino oligomers

Authors:
Phumesin P, Junking M, Panya A, Yongpitakwattana P, Noisakran S, Limjindaporn T, Yenchitsomanus PT
Citation:
Virus Res. 2019 Jan 15;260:123-128. doi: 10.1016/j.virusres.2018.11.014. Epub 2018 Nov 29. PMID: 30503719
Epub:
Yes
Abstract:
Skin dendritic cells (DCs) are primary target cells of dengue virus (DENV) infection and they play an important role in its...
Link:
https://linkinghub.elsevier.com/retrieve/pii/S0168-1702(18)30380-0
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: human monocyte-derived dendritic cells (MDDC)
Citation Extract:
Phumesin P, Junking M, Panya A, Yongpitakwattana P, Noisakran S, Limjindaporn T, Yenchitsomanus PT. Inhibition of dengue virus replication in monocyte-derived dendritic cells by vivo-morpholino oligomers. Virus Res. 2019 Jan 15;260:123-128. doi: 10.1016/j.virusres.2018.11.014. Epub 2018 Nov 29. PMID: 30503719.

Physiological effects of KDM5C on neural crest migration and eye formation during vertebrate development

Authors:
Kim Y, Jeong Y, Kwon K, Ismail T, Lee H-K, Kim C, Park J-W, Kwon O-S, Kang B-S, Lee D-S, Park TJ, Kwon T, Lee H-S
Citation:
Epigenet & Chromatin. 2018;11:72 doi:10.1186/s13072-018-0241-x
Epub:
Not Epub
Abstract:
Background: Lysine-specific histone demethylase 5C (KDM5C) belongs to the jumonji family of demethylases and is specific for...
Link:
https://epigeneticsandchromatin.biomedcentral.com/articles/10.1186/s13072-018-0241-x
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Kim Y, Jeong Y, Kwon K, Ismail T, Lee H-K, Kim C, Park J-W, Kwon O-S, Kang B-S, Lee D-S, Park TJ, Kwon T, Lee H-S. Physiological effects of KDM5C on neural crest migration and eye formation during vertebrate development. Epigenet & Chromatin. 2018;11:72 doi:10.1186/s13072-018-0241-x.

Fer1l6 Is Essential for the Development of Vertebrate Muscle Tissue in Zebrafish

Authors:
Bonventre JA, Holman C, Manchanda A, Codding SJ, Chau T, Huegel J, Barton C, Tanguay R, Johnson CP
Citation:
Mol Biol Cell. 2018 Dec 5:mbcE18060401. doi: 10.1091/mbc.E18-06-0401. [Epub ahead of print]
Epub:
Yes
Abstract:
The precise spatial and temporal expression of genes is essential for proper organismal development. Despite their importance...
Link:
https://www.molbiolcell.org/doi/abs/10.1091/mbc.E18-06-0401
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bonventre JA, Holman C, Manchanda A, Codding SJ, Chau T, Huegel J, Barton C, Tanguay R, Johnson CP. Fer1l6 Is Essential for the Development of Vertebrate Muscle Tissue in Zebrafish. Mol Biol Cell. 2018 Dec 5:mbcE18060401. doi: 10.1091/mbc.E18-06-0401. [Epub ahead of print].

Somatic uniparental disomy with a rare EFL1 variant causes Shwachman-Diamond syndrome through dysregulating ribosomal protein synthesis

Authors:
Lee S, Shin CH, Hong CR, Kim J-D, Kim A-R, Lee J, Kokhan O, Yoo T, Sohn YB, Kim O-K, Ko JM, Cho T-J, Wright NT, Jin S-W, Kang HJ, Kim HH, Choi M
Citation:
bioRxiv. 2018;[Preprint] doi:10.1101/483362
Epub:
Yes
Abstract:
We present three unrelated Korean Shwachman-Diamond syndrome (SDS) patients that carry an incomplete but identical homozygous...
Link:
https://www.biorxiv.org/content/early/2018/12/04/483362
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lee S, Shin CH, Hong CR, Kim J-D, Kim A-R, Lee J, Kokhan O, Yoo T, Sohn YB, Kim O-K, Ko JM, Cho T-J, Wright NT, Jin S-W, Kang HJ, Kim HH, Choi M. Somatic uniparental disomy with a rare EFL1 variant causes Shwachman-Diamond syndrome through dysregulating ribosomal protein synthesis. bioRxiv. 2018;[Preprint] doi:10.1101/483362 .

Dysregulation of NRAP degradation by KLHL41 contributes to pathophysiology in Nemaline Myopathy

Authors:
Jirka C, Pak JH, Grosgogeat CA, Marchetii MM, Gupta VA
Citation:
bioRxiv. 2018:[Preprint] doi:10.1101/487454
Epub:
Not Epub
Abstract:
Nemaline myopathy (NM) is the most common form of congenital myopathy that results in hypotonia and muscle weakness. This...
Link:
https://www.biorxiv.org/content/early/2018/12/04/487454
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jirka C, Pak JH, Grosgogeat CA, Marchetii MM, Gupta VA. Dysregulation of NRAP degradation by KLHL41 contributes to pathophysiology in Nemaline Myopathy. bioRxiv. 2018:[Preprint] doi:10.1101/487454.

Precursor miRNAs are trafficked along axons associated with vesicles and locally processed to regulate growth cone steering

Authors:
Corradi E, Gavoci A, Strohbuecker S, Roccuzzo M, Costa ID, Iyer A, Bridi S, Rodriguez GS, Abreu-Goodger C, Baudet M-L
Citation:
bioRxive. 2018;[Preprint] doi:10.1101/470393
Epub:
Yes
Abstract:
Various species of non-coding RNAs (ncRNAs) are enriched in subcellular compartments but the mechanisms orchestrating their...
Link:
https://www.biorxiv.org/content/early/2018/11/14/470393
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Corradi E, Gavoci A, Strohbuecker S, Roccuzzo M, Costa ID, Iyer A, Bridi S, Rodriguez GS, Abreu-Goodger C, Baudet M-L. Precursor miRNAs are trafficked along axons associated with vesicles and locally processed to regulate growth cone steering. bioRxive. 2018;[Preprint] doi:10.1101/470393.

Tfap2a is a novel gatekeeper of differentiation in renal progenitors during kidney development

Authors:
Chambers BE, Gerlach GF, Chen KH, Clark EG, Leshchiner I, Goessling W, Wingert RA
Citation:
bioRxive. 2018;[Preprint] doi:10.1101/460105
Epub:
Yes
Abstract:
Renal functional units known as nephrons undergo patterning events during development that create a segmental array of cellular...
Link:
https://www.biorxiv.org/content/early/2018/11/02/460105
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chambers BE, Gerlach GF, Chen KH, Clark EG, Leshchiner I, Goessling W, Wingert RA. Tfap2a is a novel gatekeeper of differentiation in renal progenitors during kidney development. bioRxive. 2018;[Preprint] doi:10.1101/460105.

Wolf-Hirschhorn Syndrome-associated genes are enriched in motile neural crest and affect craniofacial development in Xenopus laevis

Authors:
Mills A, Bearce E, Cella R, Kim SW, Selig M, Lee S, Lowery LA
Citation:
bioRxive. 2018;[Preprint] doi:10.1101/471672
Epub:
Yes
Abstract:
Wolf-Hirschhorn Syndrome (WHS) is a human developmental disorder arising from a hemizygous perturbation, typically a...
Link:
https://www.biorxiv.org/content/early/2018/11/15/471672.1
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Mills A, Bearce E, Cella R, Kim SW, Selig M, Lee S, Lowery LA. Wolf-Hirschhorn Syndrome-associated genes are enriched in motile neural crest and affect craniofacial development in Xenopus laevis. bioRxive. 2018;[Preprint] doi:10.1101/471672.

Fgf3 is crucial for the generation of monoaminergic cerebrospinal fluid contacting cells in zebrafish

Authors:
Reuter I, Jaeckels J, Kneitz S, Kuper J, Lesch K-P, Lillesaar C
Citation:
bioRxive. 2018;[Preprint] doi:10.1101/477323
Epub:
Yes
Abstract:
In most vertebrates, including zebrafish, the hypothalamic serotonergic cerebrospinal fluid-contacting (CSF-c) cells constitute...
Link:
https://www.biorxiv.org/content/early/2018/11/24/477323
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Reuter I, Jaeckels J, Kneitz S, Kuper J, Lesch K-P, Lillesaar C. Fgf3 is crucial for the generation of monoaminergic cerebrospinal fluid contacting cells in zebrafish. bioRxive. 2018;[Preprint] doi:10.1101/477323 .

Inhibition of microRNA suppression of Dishevelled results in Wnt pathway associated developmental defects

Authors:
Sampilo NF, Stepicheva NA, Zaidi SAM, Wang L, Wu W, Wikramanayake A, Song JL
Citation:
Development. 2018 Nov 2. pii: dev.167130. doi: 10.1242/dev.167130. [Epub ahead of print]
Epub:
Yes
Abstract:
MicroRNAs (miRNAs) are highly conserved, small non-coding RNAs that regulate gene expressions by binding to the 3'...
Link:
http://dev.biologists.org/content/145/23/dev167130
Delivery Method:
microinjection
Organism or Cell Type:
sea urchin
Citation Extract:
Sampilo NF, Stepicheva NA, Zaidi SAM, Wang L, Wu W, Wikramanayake A, Song JL. Inhibition of microRNA suppression of Dishevelled results in Wnt pathway associated developmental defects. Development. 2018 Nov 2. pii: dev.167130. doi: 10.1242/dev.167130. [Epub ahead of print].

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