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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Regulation of cardiovascular development and integrity by the heart of glass-cerebral cavernous malformation protein pathway

Authors:
Kleaveland B, Zheng X, Liu JJ, Blum Y, Tung JJ, Zou Z, Chen M, Guo L, Lu MM, Zhou D, Kitajewski J, Affolter M, Ginsberg MH, Kahn ML
Citation:
Nat Med. 2009 Jan 18. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Cerebral cavernous malformations (CCMs) are human vascular malformations caused by mutations in three genes of unknown function...
Organism or Cell Type:
zebrafish
Citation Extract:
Kleaveland B, Zheng X, Liu JJ, Blum Y, Tung JJ, Zou Z, Chen M, Guo L, Lu MM, Zhou D, Kitajewski J, Affolter M, Ginsberg MH, Kahn ML. Regulation of cardiovascular development and integrity by the heart of glass-cerebral cavernous malformation protein pathway. Nat Med. 2009 Jan 18. [Epub ahead of print].

Regulatory back-up circuit of medaka Wt1 co-orthologs ensures PGC maintenance

Authors:
Klüver N, Herpin A, Braasch I, Drieβle J, Schartl M
Citation:
Dev Biol. 2008 Nov 1. [Epub ahead of print]
Epub:
Not Epub
Abstract:
In mammals, the Wilms' tumor suppressor gene, Wt1, encodes a transcription factor critical for development of the...
Organism or Cell Type:
medaka
Citation Extract:
Klüver N, Herpin A, Braasch I, Drieβle J, Schartl M. Regulatory back-up circuit of medaka Wt1 co-orthologs ensures PGC maintenance. Dev Biol. 2008 Nov 1. [Epub ahead of print].

Requirement of vasculogenesis and blood circulation in late stages of liver growth in zebrafish

Authors:
Korzh S, Pan X, Garcia-Lecea M, Winata CL, Pan X, Wohland T, Korzh V, Gong Z
Citation:
BMC Dev Biol. 2008 Sep 16;8(1):84. [Epub ahead of print]
Epub:
Not Epub
Abstract:
ABSTRACT: BACKGROUND: Early events in vertebrate liver development have been the major focus in previous studies, however, late...
Organism or Cell Type:
zebrafish
Citation Extract:
Korzh S, Pan X, Garcia-Lecea M, Winata CL, Pan X, Wohland T, Korzh V, Gong Z. Requirement of vasculogenesis and blood circulation in late stages of liver growth in zebrafish. BMC Dev Biol. 2008 Sep 16;8(1):84. [Epub ahead of print].

Resistance to chemotherapeutic drugs overcome by c-Myc inhibition in a Lewis lung carcinoma murine model

Authors:
Knapp DC, Mata JE, Reddy MT, Devi GR, Iversen PL
Citation:
Anticancer Drugs. 2003 Jan;14(1):39-47
Epub:
Not Epub
Abstract:
Chemotherapy resistance is a significant obstacle in lung cancer therapy, and has been found to frequently correlate with...
Delivery Method:
In vivo: injection and cell culture
Organism or Cell Type:
C57BL/6 mice with LLC cell injected
Citation Extract:
Knapp DC, Mata JE, Reddy MT, Devi GR, Iversen PL. Resistance to chemotherapeutic drugs overcome by c-Myc inhibition in a Lewis lung carcinoma murine model. Anticancer Drugs. 2003 Jan;14(1):39-47.

Retinoid signaling controls mouse pancreatic exocrine lineage selection through epithelial-mesenchymal interactions

Authors:
Kobayashi H, Spilde TL, Bhatia AM, Buckingham RB, Hembree MJ, Prasadan K, Preuett BL, Imamura M, Gittes GK
Citation:
Gastroenterology. 2002 Oct;123(4):1331-40
Epub:
Not Epub
Abstract:
BACKGROUND & AIMS: The early embryonic pancreas gives rise to exocrine (ducts and acini) and endocrine lineages. Control of...
Delivery Method:
oligo bathing
Organism or Cell Type:
Mouse pancreas explants or epithelia
Citation Extract:
Kobayashi H, Spilde TL, Bhatia AM, Buckingham RB, Hembree MJ, Prasadan K, Preuett BL, Imamura M, Gittes GK. Retinoid signaling controls mouse pancreatic exocrine lineage selection through epithelial-mesenchymal interactions. Gastroenterology. 2002 Oct;123(4):1331-40.

RNA modulation, repair and remodeling by splice switching oligonucleotides

Authors:
Kole R, Williams T, Cohen L
Citation:
Acta Biochim Pol. 2004;51(2):373-8
Epub:
Not Epub
Abstract:
Targeting splicing by antisense oligonucleotides allows RNA modifications that are not possible with RNA interference or other...
Delivery Method:
not applicable
Organism or Cell Type:
not applicable
Citation Extract:
Kole R, Williams T, Cohen L. RNA modulation, repair and remodeling by splice switching oligonucleotides. Acta Biochim Pol. 2004;51(2):373-8.

RNA therapeutics: beyond RNA interference and antisense oligonucleotides

Authors:
Kole R, Krainer AR, Altman S
Citation:
Nat Rev Drug Discov. 2012 Jan 20. doi: 10.1038/nrd3625. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Here, we discuss three RNA-based therapeutic technologies exploiting various oligonucleotides that bind to RNA by base pairing...
Organism or Cell Type:
various
Citation Extract:
Kole R, Krainer AR, Altman S. RNA therapeutics: beyond RNA interference and antisense oligonucleotides. Nat Rev Drug Discov. 2012 Jan 20. doi: 10.1038/nrd3625. [Epub ahead of print].

SARS-Coronavirus triggers apoptosis via protein kinase R but is resistant to its antiviral activity

Authors:
Krähling V, Stein DA, Spiegel M, Weber F, Mühlberger E
Citation:
J Virol. 2008 Dec 24. [Epub ahead of print]
Epub:
Not Epub
Abstract:
In this study, infection of 293/ACE2 cells with SARS-CoV activated several apoptosis-associated events, namely, cleavage of...
Link:
https://jvi.asm.org/content/83/5/2298
Delivery Method:
peptide-coupled
Organism or Cell Type:
cell culture: 293/ACE2
Citation Extract:
Krähling V, Stein DA, Spiegel M, Weber F, Mühlberger E. SARS-Coronavirus triggers apoptosis via protein kinase R but is resistant to its antiviral activity. J Virol. 2008 Dec 24. [Epub ahead of print].

Simplet controls cell proliferation and gene transcription during zebrafish caudal fin regeneration

Authors:
Kizil C, Otto GW, Geisler R, Nüsslein-Volhard C, Antos CL
Citation:
Dev Biol. 2008 Oct 17. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Two hallmarks of vertebrate epimorphic regeneration are a significant increase in the proliferation of normally quiescent cells...
Organism or Cell Type:
zebrafish
Citation Extract:
Kizil C, Otto GW, Geisler R, Nüsslein-Volhard C, Antos CL. Simplet controls cell proliferation and gene transcription during zebrafish caudal fin regeneration. Dev Biol. 2008 Oct 17. [Epub ahead of print].

Skeletal and pigment cell defects in the lockjaw mutant reveal multiple roles for zebrafish tfap2a in neural crest development

Authors:
Knight RD, Javidan Y, Nelson S, Zhang T, Schilling T
Citation:
Dev Dyn. 2004 Jan;229(1):87-98
Epub:
Not Epub
Abstract:
Members of the AP-2 transcription factor family have critical roles in many aspects of embryonic development. The zebrafish...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Knight RD, Javidan Y, Nelson S, Zhang T, Schilling T. Skeletal and pigment cell defects in the lockjaw mutant reveal multiple roles for zebrafish tfap2a in neural crest development. Dev Dyn. 2004 Jan;229(1):87-98.

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