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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Duplications of BHLHA9 are associated with ectrodactyly and tibia hemimelia inherited in non-Mendelian fashion
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Citation:
J Med Genet. 2011;[Epub ahear of print] doi:10.1136/jmedgenet-2011-100409 Epub:
Not Epub Abstract:
Background: Split-hand/foot malformation (SHFM)—also known as ectrodactyly—is a congenital disorder characterised by severe... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Klopocki E, Lohan S, Doelken SC, Stricker S, Ockeloen CW, de Aguiar RST, Lezirovitz K, Netto RCM, Jamsheer A, Shah H, Kurth I, Habenicht R, Warman M, Devriendt K, Kordaß U, Hempel M, Rajab A, Mäkitie O, Naveed M, Radhakrishna U, Antonarakis SE, Horn D, Mundlos S. Duplications of BHLHA9 are associated with ectrodactyly and tibia hemimelia inherited in non-Mendelian fashion. J Med Genet. 2011;[Epub ahear of print] doi:10.1136/jmedgenet-2011-100409. |
Dynamin 2 homozygous mutation in humans with a lethal congenital syndrome
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Citation:
Eur J Hum Genet. 2012 Oct 24. doi: 10.1038/ejhg.2012.226. [Epub ahead of print] Epub:
Not Epub Abstract:
Heterozygous mutations in dynamin 2 (DNM2) have been linked to dominant Charcot-Marie-Tooth neuropathy and centronuclear... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Koutsopoulos OS, Kretz C, Weller CM, Roux A, Mojzisova H, Böhm J, Koch C, Toussaint A, Heckel E, Stemkens D, Ter Horst SA, Thibault C, Koch M, Mehdi SQ, Bijlsma EK, Mandel JL, Vermot J, Laporte J. Dynamin 2 homozygous mutation in humans with a lethal congenital syndrome. Eur J Hum Genet. 2012 Oct 24. doi: 10.1038/ejhg.2012.226. [Epub ahead of print]. |
Ectodermal syndecan-2 mediates left-right axis formation in migrating mesoderm as a cell-nonautonomous Vg1 cofactor
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Citation:
Dev Cell 2002 Jan;2(1):115-24 Epub:
Not Epub Abstract:
Heparan sulfate proteoglycans expressed on the Xenopus animal cap ectoderm have been implicated in transmitting left-right... Delivery Method:
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Xenopus Citation Extract: Kramer KL, Yost HJ. Ectodermal syndecan-2 mediates left-right axis formation in migrating mesoderm as a cell-nonautonomous Vg1 cofactor. Dev Cell 2002 Jan;2(1):115-24. |
Elr-type proteins protect Xenopus Dead end mRNA from miR-18-mediated clearance in the soma
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Citation:
Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16148-53. Epub 2010 Aug 30 Epub:
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Segregation of the future germ line defines a crucial cell fate decision during animal development. In Xenopus, germ cells are... Organism or Cell Type:
Xenopus Citation Extract: Koebernick K, Loeber J, Arthur PK, Tarbashevich K, Pieler T. Elr-type proteins protect Xenopus Dead end mRNA from miR-18-mediated clearance in the soma. Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16148-53. Epub 2010 Aug 30 . |
Embryonic lethality of fortilin-null mutant mice by BMP-pathway overactivation
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Citation:
Biochim Biophys Acta. 2009 May;1790(5):326-38. Epub 2009 Feb 7 Epub:
Not Epub Abstract:
BACKGROUND: Fortilin negatively regulates apoptosis and is overexpressed in cancer. However, the role of fortilin in mammalian... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Koide Y, Kiyota T, Tonganunt M, Pinkaew D, Liu Z, Kato Y, Hutadilok-Towatana N, Phongdara A, Fujise K. Embryonic lethality of fortilin-null mutant mice by BMP-pathway overactivation. Biochim Biophys Acta. 2009 May;1790(5):326-38. Epub 2009 Feb 7. |
Embryonic Senescence and Laminopathies in a Progeroid Zebrafish Model
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Citation:
PLoS ONE. 2011;6(3): e17688. doi:10.1371/journal.pone.0017688 Epub:
Not Epub Abstract:
Background Mutations that disrupt the conversion of prelamin A to mature lamin A cause the rare genetic disorder Hutchinson-... Delivery Method:
microinjection in embryos, Endo-Porter in cultures Organism or Cell Type:
zebrafish and zebrafish cell culture (AB9 fibroblasts) Citation Extract: Koshimizu E, Imamura S, Qi J, Toure J, Valdez DM Jr, Carr CE, Hanai J, Kishi S. Embryonic Senescence and Laminopathies in a Progeroid Zebrafish Model. PLoS ONE. 2011;6(3): e17688. doi:10.1371/journal.pone.0017688. |
En2, Pax2/5 and Tcf-4 transcription factors cooperate in patterning the Xenopus brain
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Citation:
Dev Biol. 2010 Apr 15;340(2):318-28. Epub 2010 Feb 18 Epub:
Not Epub Abstract:
Among Xenopus Lef/Tcfs, XTcf-4 has an outstanding role. In early development it is located exclusively in the midbrain where it... Organism or Cell Type:
Xenopus Citation Extract: Koenig SF, Brentle S, Hamdi K, Fichtner D, Wedlich D, Gradl D. En2, Pax2/5 and Tcf-4 transcription factors cooperate in patterning the Xenopus brain. Dev Biol. 2010 Apr 15;340(2):318-28. Epub 2010 Feb 18. |
Essential role of HGF (hepatocyte growth factor) in blood formation in Xenopus
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Citation:
Blood. 2004 May 1;103(9):3320-5 Epub:
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In this study, we investigated the role of hepatocyte growth factor (HGF) in blood formation during Xenopus development. First... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Koibuchi N, Kaneda Y, Taniyama Y, Matsumoto K, Nakamura T, Ogihara T, Morishita R. Essential role of HGF (hepatocyte growth factor) in blood formation in Xenopus. Blood. 2004 May 1;103(9):3320-5. |
Ethanol induces embryonic malformations by competing for retinaldehyde dehydrogenase activity during vertebrate gastrulation
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Citation:
Dis Model Mech. 2009 May-Jun;2(5-6):295-305. Epub 2009 Apr 6 Epub:
Not Epub Abstract:
Human embryos exposed to alcohol (ethanol) develop a complex developmental phenotype known as fetal alcohol spectrum disorder (... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Kot-Leibovich H, Fainsod A. Ethanol induces embryonic malformations by competing for retinaldehyde dehydrogenase activity during vertebrate gastrulation. Dis Model Mech. 2009 May-Jun;2(5-6):295-305. Epub 2009 Apr 6. |
Functional characterization of the Bcl-2 gene family in the zebrafish
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Citation:
Cell Death Differ. 2006 Oct;13(10):1631-40. Epub 2006 Aug 4. Epub:
Not Epub Abstract:
Members of the Bcl-2 protein family control the intrinsic apoptosis pathway. To evaluate the importance of this family in... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Kratz E, Eimon PM, Mukhyala K, Stern H, Zha J, Strasser A, Hart R, Ashkenazi A. Functional characterization of the Bcl-2 gene family in the zebrafish. Cell Death Differ. 2006 Oct;13(10):1631-40. Epub 2006 Aug 4.. |