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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Dantrolene Enhances Antisense-Mediated Exon Skipping in Human and Mouse Models of Duchenne Muscular Dystrophy
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Citation:
Sci Transl Med. 2012 4:164ra160. doi:10.1126/scitranslmed.3005054 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) causes profound and progressive muscle weakness and loss, resulting in early death. DMD is... Delivery Method:
in vivo: injection Organism or Cell Type:
mice, mdx Citation Extract: Kendall GC, Mokhonova EI, Moran M, Sejbuk NE, Wang DW, Silva O, Wang RT, Martinez L, Lu QL, Damoiseaux R, Spencer MJ, Nelson SF, Miceli MC. Dantrolene Enhances Antisense-Mediated Exon Skipping in Human and Mouse Models of Duchenne Muscular Dystrophy. Sci Transl Med. 2012 4:164ra160. doi:10.1126/scitranslmed.3005054 . |
delta-Np63-alpha Is an Oncogene that Targets Chromatin Remodeler Lsh to Drive Skin Stem Cell Proliferation and Tumorigenesis
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Citation:
Cell stem cell. 2011;8(2):164-76 doi:10.1016/j.stem.2010.12.009 Epub:
Not Epub Abstract:
The p53 homolog p63 is essential for development, yet its role in cancer is not clear. We discovered that p63 deficiency evokes... Citation Extract: Keyes WM, Pecoraro M, Aranda V, Vernersson-Lindahl E, Li W, Vogel H, Guo X, Garcia EL, Michurina TV, Enikolopov G, Muthuswamy SK, Mills AA. delta-Np63-alpha Is an Oncogene that Targets Chromatin Remodeler Lsh to Drive Skin Stem Cell Proliferation and Tumorigenesis. Cell stem cell. 2011;8(2):164-76 doi:10.1016/j.stem.2010.12.009. |
Depletion of three BMP antagonists from Spemann's organizer leads to a catastrophic loss of dorsal structures
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Citation:
Dev Cell. 2005 Mar;8(3):401-11 Epub:
Not Epub Abstract:
Transplanted Spemann's organizer induces dorsal embryonic cell fates such as the nervous system and somites, but in normal... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Khokha MK, Yeh J, Grammer TC, Harland RM. Depletion of three BMP antagonists from Spemann's organizer leads to a catastrophic loss of dorsal structures. Dev Cell. 2005 Mar;8(3):401-11. |
ENU-induced Mutation in the DNA-binding Domain of KLF3 Reveals Important Roles for KLF3 in Cardiovascular Development and Function in Mice
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Citation:
PLoS Genet. 2013;9(7):e1003612. doi:10.1371/journal.pgen.1003612 Epub:
Not Epub Abstract:
KLF3 is a Krüppel family zinc finger transcription factor with widespread tissue expression and no previously known role in... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Kelsey L, Flenniken AM, Qu D, Funnell APW, Pearson R, Zhou Y-Q, Voronina I, Berberovic Z, Wood G, Newbigging S, Weiss ES, Wong M, Quach I, Yeh SY, Deshwar AR, Scott IC, McKerlie C, Henkelman M, Backx P, Simpson J, Osborne L, Rossant J, Crossley M, Bruneau B, Adamson SL. ENU-induced Mutation in the DNA-binding Domain of KLF3 Reveals Important Roles for KLF3 in Cardiovascular Development and Function in Mice. PLoS Genet. 2013;9(7):e1003612. doi:10.1371/journal.pgen.1003612. |
EphA4 and EfnB2a maintain rhombomere coherence by independently regulating intercalation of progenitor cells in the zebrafish neural keel
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Citation:
Dev Biol. 2009 Mar 15;327(2):313-26. Epub 2008 Dec 24 Epub:
Not Epub Abstract:
During vertebrate development, the hindbrain is transiently segmented into 7 distinct rhombomeres (r). Hindbrain segmentation... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Kemp HA, Cooke JE, Moens CB. EphA4 and EfnB2a maintain rhombomere coherence by independently regulating intercalation of progenitor cells in the zebrafish neural keel. Dev Biol. 2009 Mar 15;327(2):313-26. Epub 2008 Dec 24. |
Essential role for beta-arrestin 2 in the regulation of Xenopus convergent extension movements
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Citation:
EMBO J. 2007 May 16;26(10):2513-26. Epub 2007 May 3 Epub:
Not Epub Abstract:
beta-Arrestin 2 (betaarr2) is a multifunctional protein that regulates numerous aspects of G-protein-coupled receptor function... Organism or Cell Type:
Xenopus Citation Extract: Kim GH, Han JK. Essential role for beta-arrestin 2 in the regulation of Xenopus convergent extension movements. EMBO J. 2007 May 16;26(10):2513-26. Epub 2007 May 3. |
gbx2 Homeobox gene is required for the maintenance of the isthmic region in the zebrafish embryonic brain
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Citation:
Dev Dyn. 2003 Nov;228(3):433-50 Epub:
Not Epub Abstract:
We isolated cDNA clones for the zebrafish gbx2 gene, which is implicated in the establishment of the midbrain-hindbrain... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Kikuta H, Kanai M, Ito Y, Yamasu K. gbx2 Homeobox gene is required for the maintenance of the isthmic region in the zebrafish embryonic brain. Dev Dyn. 2003 Nov;228(3):433-50. |
Geminin Is Required for Zygotic Gene Expression at the Xenopus Mid-Blastula Transition
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Citation:
PLoS ONE. 2012;7(5): e38009. doi:10.1371/journal.pone.0038009 Epub:
Not Epub Abstract:
In many organisms early development is under control of the maternal genome and zygotic gene expression is delayed until the... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Kerns SL, Schultz KM, Barry KA, Thorne TM, McGarry TJ. Geminin Is Required for Zygotic Gene Expression at the Xenopus Mid-Blastula Transition. PLoS ONE. 2012;7(5): e38009. doi:10.1371/journal.pone.0038009. |
HtrA1 is a novel antagonist controlling fibroblast growth factor (FGF) signaling via cleavage of FGF8
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Citation:
Mol Cell Biol. 2012 Nov;32(21):4482-92. doi: 10.1128/MCB.00872-12. Epub 2012 Sep 4 Epub:
Not Epub Abstract:
Accumulating evidence suggests that HtrA1 (high-temperature requirement A1) is involved in modulating crucial cellular... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Kim GY, Kim HY, Kim HT, Moon JM, Kim CH, Kang S, Rhim H. HtrA1 is a novel antagonist controlling fibroblast growth factor (FGF) signaling via cleavage of FGF8. Mol Cell Biol. 2012 Nov;32(21):4482-92. doi: 10.1128/MCB.00872-12. Epub 2012 Sep 4. |
Lens and retina formation require expression of Pitx3 in Xenopus pre-lens ectoderm
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Citation:
Dev Dyn. 2005 Nov;234(3):577-89. Epub:
Not Epub Abstract:
Pitx3 is expressed in tissues fated to contribute to eye development, namely, neurula stage ectoderm and prechordal mesoderm,... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Khosrowshahian F, Wolanski M, Chang WY, Fujiki K, Jacobs L, Crawford MJ. Lens and retina formation require expression of Pitx3 in Xenopus pre-lens ectoderm. Dev Dyn. 2005 Nov;234(3):577-89.. |