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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Radiolabeling oligo nuclieotide with 90Y and its radiolysis

Authors:
Liu C, Tian J, Zhang J
Citation:
Chinese Journal of Nuclear Medicine. 2005;4: (Chinese)
Epub:
Not Epub
Abstract:
目的用90Y标记人工合成的Morpholino(MORF)寡核苷酸.方法将双功能螯合剂DOTA偶联到MORF 3'末端的氨基上,用90Y进行标记,常规检测其生物活性及体外稳定性.结果高效液相色谱(HPLC)及薄层层析证实,90Y-...
Citation Extract:
Liu C, Tian J, Zhang J. Radiolabeling oligo nuclieotide with 90Y and its radiolysis. Chinese Journal of Nuclear Medicine. 2005;4: (Chinese).

Rapid activation of protein tyrosine kinase and phospholipase C-gamma2 and increase in cytosolic free calcium are required by Ehrlichia chaffeensis for internalization and growth in THP-1 cells

Authors:
Lin M, Zhu MX, Rikihisa Y
Citation:
Infect Immun. 2002 Feb;70(2):889-98
Epub:
Not Epub
Abstract:
Ehrlichia chaffeensis, a bacterium that cannot survive outside the eukaryotic cell, proliferates exclusively in human monocytes...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: THP-1 cells
Citation Extract:
Lin M, Zhu MX, Rikihisa Y. Rapid activation of protein tyrosine kinase and phospholipase C-gamma2 and increase in cytosolic free calcium are required by Ehrlichia chaffeensis for internalization and growth in THP-1 cells. Infect Immun. 2002 Feb;70(2):889-98.

Replacing 99mTc with 111In improves MORF/cMORF pretargeting by reducing intestinal accumulation

Authors:
Liu G, Cheng D, Dou S, Chen X, Liang M, Pretorius PH, Rusckowski M, Hnatowich DJ
Citation:
Mol Imaging Biol. 2009 Sep-Oct;11(5):303-7. doi: 10.1007/s11307-009-0209-0. Epub 2009 Mar 27
Epub:
Not Epub
Abstract:
PURPOSE: To reduce accumulation in the abdomen by MORF/cMORF pretargeting, 111In was compared to 99mTc as the radiolabel....
Link:
http://link.springer.com/article/10.1007%2Fs11307-009-0209-0
Delivery Method:
Injection
Organism or Cell Type:
mice
Citation Extract:
Liu G, Cheng D, Dou S, Chen X, Liang M, Pretorius PH, Rusckowski M, Hnatowich DJ. Replacing 99mTc with 111In improves MORF/cMORF pretargeting by reducing intestinal accumulation. Mol Imaging Biol. 2009 Sep-Oct;11(5):303-7. doi: 10.1007/s11307-009-0209-0. Epub 2009 Mar 27.

Retina development in zebrafish requires the heparan sulfate proteoglycan agrin

Authors:
Liu IH, Zhang C, Kim MJ, Cole GJ
Citation:
Dev Neurobiol. 2008 Jun;68(7):877-98.
Epub:
Not Epub
Abstract:
Recent studies from our laboratory have begun to elucidate the role of agrin in zebrafish development. One agrin morphant...
Organism or Cell Type:
zebrafish
Citation Extract:
Liu IH, Zhang C, Kim MJ, Cole GJ. Retina development in zebrafish requires the heparan sulfate proteoglycan agrin. Dev Neurobiol. 2008 Jun;68(7):877-98..

Reverse Effect of Mammalian Hypocalcemic Cortisol in Fish: Cortisol Stimulates Ca2+ Uptake via Glucocorticoid Receptor-Mediated Vitamin D3 Metabolism

Authors:
Lin CH, Tsai IL, Su CH, Tseng DY, Hwang PP
Citation:
PLoS ONE. 2011;6(8): e23689. doi:10.1371/journal.pone.0023689
Epub:
Not Epub
Abstract:
Cortisol was reported to downregulate body-fluid Ca2+ levels in mammals but was proposed to show hypercalcemic effects in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin CH, Tsai IL, Su CH, Tseng DY, Hwang PP. Reverse Effect of Mammalian Hypocalcemic Cortisol in Fish: Cortisol Stimulates Ca2+ Uptake via Glucocorticoid Receptor-Mediated Vitamin D3 Metabolism. PLoS ONE. 2011;6(8): e23689. doi:10.1371/journal.pone.0023689.

Serotonin stimulation of cAMP-dependent plasticity in Aplysia sensory neurons is mediated by calmodulin-sensitive adenylyl cyclase

Authors:
Lin AH, Cohen JE, Wan Q, Niu K, Shrestha P, Bernstein SL, Abrams TW
Citation:
Proc Natl Acad Sci U S A. 2010 Aug 31;107(35):15607-12. Epub 2010 Aug 11
Epub:
Not Epub
Abstract:
Calmodulin (CaM)-sensitive adenylyl cyclase (AC) in sensory neurons (SNs) in Aplysia has been proposed as a molecular...
Delivery Method:
in vivo injection into neurons
Organism or Cell Type:
Aplysia
Citation Extract:
Lin AH, Cohen JE, Wan Q, Niu K, Shrestha P, Bernstein SL, Abrams TW. Serotonin stimulation of cAMP-dependent plasticity in Aplysia sensory neurons is mediated by calmodulin-sensitive adenylyl cyclase. Proc Natl Acad Sci U S A. 2010 Aug 31;107(35):15607-12. Epub 2010 Aug 11.

Spacer-length dependence of programmed −1 or −2 ribosomal frameshifting on a U6A heptamer supports a role for messenger RNA (mRNA) tension in frameshifting

Authors:
Lin Z, Gilbert RJC, Brierley I
Citation:
Nucl. Acids Res. 2012 June 28. [Epub ahead of print] doi:10.1093/nar/gks629
Epub:
Not Epub
Abstract:
Programmed −1 ribosomal frameshifting is employed in the expression of a number of viral and cellular genes. In this process,...
Organism or Cell Type:
Cell culture: COS-7 cells (monkey kidney)
Citation Extract:
Lin Z, Gilbert RJC, Brierley I. Spacer-length dependence of programmed −1 or −2 ribosomal frameshifting on a U6A heptamer supports a role for messenger RNA (mRNA) tension in frameshifting. Nucl. Acids Res. 2012 June 28. [Epub ahead of print] doi:10.1093/nar/gks629 .

Successful Radiotherapy of Tumor in Pretargeted Mice by 188Re-Radiolabeled Phosphorodiamidate Morpholino Oligomer, a Synthetic DNA Analogue

Authors:
Liu G, Dou S, Mardirossian G, He J, Zhang S, Liu X, Rusckowski M, Hnatowich DJ
Citation:
Clin Cancer Res. 2006 Aug 15;12(16):4958-4964
Epub:
Not Epub
Abstract:
PURPOSE: Pretargeting has been attracting increasing attention as a drug delivery approach. We recently proposed Watson-Crick...
Delivery Method:
Injection
Organism or Cell Type:
mice
Citation Extract:
Liu G, Dou S, Mardirossian G, He J, Zhang S, Liu X, Rusckowski M, Hnatowich DJ. Successful Radiotherapy of Tumor in Pretargeted Mice by 188Re-Radiolabeled Phosphorodiamidate Morpholino Oligomer, a Synthetic DNA Analogue. Clin Cancer Res. 2006 Aug 15;12(16):4958-4964.

Systemic splicing factor deficiency causes tissue-specific defects: a zebrafish model for retinitis pigmentosa

Authors:
Linder B, Dill H, Hirmer A, Brocher J, Lee GP, Mathavan S, Bolz HJ, Winkler C, Laggerbauer B, Fischer U
Citation:
Hum Mol Genet. 2010 Nov 25. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Retinitis pigmentosa (RP) is a common hereditary eye disease that causes blindness due to a progressive loss of photoreceptors...
Organism or Cell Type:
zebrafish
Citation Extract:
Linder B, Dill H, Hirmer A, Brocher J, Lee GP, Mathavan S, Bolz HJ, Winkler C, Laggerbauer B, Fischer U. Systemic splicing factor deficiency causes tissue-specific defects: a zebrafish model for retinitis pigmentosa. Hum Mol Genet. 2010 Nov 25. [Epub ahead of print].

TAK1 promotes BMP4/Smad1 signaling via inhibition of erk MAPK: A new link in the FGF/BMP regulatory network

Authors:
Liu C, Goswami M, Talley J, Chesser-Martinez PL, Lou CH, Sater AK
Citation:
Differentiation. 2012 Mar 1;83(4):210-219. [Epub ahead of print]
Epub:
Not Epub
Abstract:
FGFs and BMPs act in concert to regulate a wide range of processes in vertebrate development. In most cases, FGFs and BMPs have...
Organism or Cell Type:
Xenopus
Citation Extract:
Liu C, Goswami M, Talley J, Chesser-Martinez PL, Lou CH, Sater AK. TAK1 promotes BMP4/Smad1 signaling via inhibition of erk MAPK: A new link in the FGF/BMP regulatory network. Differentiation. 2012 Mar 1;83(4):210-219. [Epub ahead of print].

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