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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Galpha12/13 regulate epiboly by inhibiting E-cadherin activity and modulating the actin cytoskeleton

Authors:
Lin F, Chen S, Sepich DS, Panizzi JR, Clendenon SG, Marrs JA, Hamm HE, Solnica-Krezel L
Citation:
J Cell Biol. 2009 Mar 23;184(6):909-21
Epub:
Not Epub
Abstract:
Epiboly spreads and thins the blastoderm over the yolk cell during zebrafish gastrulation, and involves coordinated movements...
Organism or Cell Type:
zebrafish
Citation Extract:
Lin F, Chen S, Sepich DS, Panizzi JR, Clendenon SG, Marrs JA, Hamm HE, Solnica-Krezel L. Galpha12/13 regulate epiboly by inhibiting E-cadherin activity and modulating the actin cytoskeleton. J Cell Biol. 2009 Mar 23;184(6):909-21.

Geminin cooperates with Polycomb to restrain multi-lineage commitment in the early embryo

Authors:
Lim JW, Hummert P, Mills JC, Kroll KL
Citation:
Development. 2011 Jan;138(1):33-44. Epub 2010 Nov 23
Epub:
Not Epub
Abstract:
Transient maintenance of a pluripotent embryonic cell population followed by the onset of multi-lineage commitment is a...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Lim JW, Hummert P, Mills JC, Kroll KL. Geminin cooperates with Polycomb to restrain multi-lineage commitment in the early embryo. Development. 2011 Jan;138(1):33-44. Epub 2010 Nov 23.

Genetic Association for Renal Traits among Participants of African Ancestry Reveals New Loci for Renal Function

Authors:
Liu CT, Garnaas MK, Tin A, Kottgen A, Franceschini N, Peralta CA, de Boer IH, Lu X, Atkinson E, Ding J, Nalls M, Shriner D, Coresh J, Kutlar A, Bibbins-Domingo K, Siscovick D, Akylbekova E, Wyatt S, Astor B, Mychaleckjy J, Man Li M, Reilly MP, Townsend RR, Adeyemo A, Zonderman AB, de Andrade M, Turner ST, Mosley TH, Harris TB, The CKDGen Consortium, Rotimi CN, Liu Y, Kardia SLR, Evans MK, Shlipak MG, Kramer H, Flessner MF, Dreisbach AW, Goessling W, Cupples LA, Kao WL, Fox CS
Citation:
PLoS Genet. 2011;7(9): e1002264. doi:10.1371/journal.pgen.1002264
Epub:
Not Epub
Abstract:
Chronic kidney disease (CKD) is an increasing global public health concern, particularly among populations of African ancestry...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu CT, Garnaas MK, Tin A, Kottgen A, Franceschini N, Peralta CA, de Boer IH, Lu X, Atkinson E, Ding J, Nalls M, Shriner D, Coresh J, Kutlar A, Bibbins-Domingo K, Siscovick D, Akylbekova E, Wyatt S, Astor B, Mychaleckjy J, Man Li M, Reilly MP, Townsend RR, Adeyemo A, Zonderman AB, de Andrade M, Turner ST, Mosley TH, Harris TB, The CKDGen Consortium, Rotimi CN, Liu Y, Kardia SLR, Evans MK, Shlipak MG, Kramer H, Flessner MF, Dreisbach AW, Goessling W, Cupples LA, Kao WL, Fox CS. Genetic Association for Renal Traits among Participants of African Ancestry Reveals New Loci for Renal Function. PLoS Genet. 2011;7(9): e1002264. doi:10.1371/journal.pgen.1002264.

Haploinsufficiency of KDM6A is associated with severe psychomotor retardation, global growth restriction, seizures and cleft palate

Authors:
Lindgren AM, Hoyos T, Talkowski ME, Hanscom C, Blumenthal I, Chiang C, Ernst C, Pereira S, Ordulu Z, Clericuzio C, Drautz JM, Rosenfeld JA, Shaffer LG, Velsher L, Pynn T, Vermeesch J, Harris DJ, Gusella JF, Liao EC, Morton CC
Citation:
Hum Genet. 2013 Jan 25. [Epub ahead of print]
Epub:
Not Epub
Abstract:
We describe a female subject (DGAP100) with a 46,X,t(X;5)(p11.3;q35.3)inv(5)(q35.3q35.1)dn, severe psychomotor retardation with...
Organism or Cell Type:
zebrafish
Citation Extract:
Lindgren AM, Hoyos T, Talkowski ME, Hanscom C, Blumenthal I, Chiang C, Ernst C, Pereira S, Ordulu Z, Clericuzio C, Drautz JM, Rosenfeld JA, Shaffer LG, Velsher L, Pynn T, Vermeesch J, Harris DJ, Gusella JF, Liao EC, Morton CC. Haploinsufficiency of KDM6A is associated with severe psychomotor retardation, global growth restriction, seizures and cleft palate. Hum Genet. 2013 Jan 25. [Epub ahead of print].

Human islet cell MORF/cMORF pretargeting in a xenogeneic murine transplant model

Authors:
Liu G, Dou S, Cheng D, Leif J, Rusckowski M, Streeter PR, Schultz LD, Hnatowich D, Greiner D
Citation:
Mol Pharm. 2011 Jun 6;8(3):767-73. doi: 10.1021/mp100382m. Epub 2011 Apr 21
Epub:
Not Epub
Abstract:
Non-invasive measurement of human islet cell mass in pancreas or following islet transplantation by nuclear imaging has yet to...
Delivery Method:
Injection
Organism or Cell Type:
mice, cell cultures
Citation Extract:
Liu G, Dou S, Cheng D, Leif J, Rusckowski M, Streeter PR, Schultz LD, Hnatowich D, Greiner D. Human islet cell MORF/cMORF pretargeting in a xenogeneic murine transplant model. Mol Pharm. 2011 Jun 6;8(3):767-73. doi: 10.1021/mp100382m. Epub 2011 Apr 21.

Human TRIM71 and Its Nematode Homologue are Targets of let-7 MicroRNA and Its Zebrafish Orthologue is Essential for Development

Authors:
Lin YC, Hsieh LC, Kuo MW, Yu J, Kuo HH, Lo WL, Lin RJ, Yu AL, Li WH
Citation:
Mol Biol Evol. 2007 Nov;24(11):2525-34. Epub 2007 Sep 21
Epub:
Not Epub
Abstract:
Animal microRNAs (miRNAs) are short RNAs that function as posttranscriptional regulators of gene expression by binding to the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin YC, Hsieh LC, Kuo MW, Yu J, Kuo HH, Lo WL, Lin RJ, Yu AL, Li WH. Human TRIM71 and Its Nematode Homologue are Targets of let-7 MicroRNA and Its Zebrafish Orthologue is Essential for Development. Mol Biol Evol. 2007 Nov;24(11):2525-34. Epub 2007 Sep 21.

Identification of differential transcript profiles between mutual crossbred embryos of zebrafish (Danio rerio) and Chinese rare minnow (Gobiocypris rarus) by cDNA-AFLP

Authors:
Liu J, Sun YH, Wang YW, Wang N, Pei DS, Wang YP, Hu W, Zhu ZY
Citation:
Theriogenology. 2008 Dec;70(9):1525-35. Epub 2008 Aug 9
Epub:
Not Epub
Abstract:
The crosstalk between naive nucleus and maternal factors deposited in egg cytoplasm before zygotic genome activation is crucial...
Organism or Cell Type:
zebrafish
Citation Extract:
Liu J, Sun YH, Wang YW, Wang N, Pei DS, Wang YP, Hu W, Zhu ZY. Identification of differential transcript profiles between mutual crossbred embryos of zebrafish (Danio rerio) and Chinese rare minnow (Gobiocypris rarus) by cDNA-AFLP. Theriogenology. 2008 Dec;70(9):1525-35. Epub 2008 Aug 9.

Identification of regulators of germ layer morphogenesis using proteomics in zebrafish

Authors:
Link V, Carvalho L, Castanon I, Stockinger P, Shevchenko A, Heisenberg CP
Citation:
J Cell Sci. 2006 May 15;119(Pt 10):2073-83. Epub 2006 Apr 25
Epub:
Not Epub
Abstract:
During vertebrate gastrulation, a well-orchestrated series of morphogenetic changes leads to the formation of the three germ...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Link V, Carvalho L, Castanon I, Stockinger P, Shevchenko A, Heisenberg CP. Identification of regulators of germ layer morphogenesis using proteomics in zebrafish. J Cell Sci. 2006 May 15;119(Pt 10):2073-83. Epub 2006 Apr 25.

Improving the Labeling of S-Acetyl NHS-MAG(3)-Conjugated Morpholino Oligomers

Authors:
Liu G, Zhang S, He J, Zhu Z, Rusckowski M, Hnatowich DJ
Citation:
Bioconjug Chem. 2002 Jul 17;13(4):893-897
Epub:
Not Epub
Abstract:
S-Acetyl MAG(3) (S-acetylmercaptoacetyltriglycine) has been used as a chelator for the (99m)Tc labeling of a variety of...
Delivery Method:
not applicable
Organism or Cell Type:
not applicable
Citation Extract:
Liu G, Zhang S, He J, Zhu Z, Rusckowski M, Hnatowich DJ. Improving the Labeling of S-Acetyl NHS-MAG(3)-Conjugated Morpholino Oligomers. Bioconjug Chem. 2002 Jul 17;13(4):893-897.

Interaction with LC8 is required for Pak1 nuclear import and is indispensable for zebrafish development

Authors:
Lightcap CM, Kari G, Arias-Romero LE, Chernoff J, Rodeck U, Williams JC
Citation:
PLoS One. 2009 Jun 26;4(6):e6025
Epub:
Not Epub
Abstract:
Pak1 (p21 activated kinase 1) is a serine/threonine kinase implicated in regulation of cell motility and survival and in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lightcap CM, Kari G, Arias-Romero LE, Chernoff J, Rodeck U, Williams JC. Interaction with LC8 is required for Pak1 nuclear import and is indispensable for zebrafish development. PLoS One. 2009 Jun 26;4(6):e6025.

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