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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

A novel pretargeting method for measuring antibody internalization in tumor cells

Authors:
Liu G, Dou S, Yin D, Squires S, Liu X, Wang Y, Rusckowski M, Hnatowich DJ
Citation:
Cancer Biother Radiopharm. 2007 Feb;22(1):33-9
Epub:
Not Epub
Abstract:
A novel pretargeting method has been developed to quantitate antibody cellular internalization. In this study, the antibody was...
Delivery Method:
oligo bathing
Citation Extract:
Liu G, Dou S, Yin D, Squires S, Liu X, Wang Y, Rusckowski M, Hnatowich DJ. A novel pretargeting method for measuring antibody internalization in tumor cells. Cancer Biother Radiopharm. 2007 Feb;22(1):33-9.

A Novel Zinc Finger Protein 219-like (ZNF219L) is Involved in the Regulation of Collagen Type 2 Alpha 1a (col2a1a) Gene Expression in Zebrafish Notochord

Authors:
Lien HW, Yang CH, Cheng CH, Hung CC, Liao WH, Hwang PP, Han YS, Huang CJ
Citation:
Int J Biol Sci. 2013;9(9):872-886. doi:10.7150/ijbs.7126
Epub:
Not Epub
Abstract:
The notochord is required for body plan patterning in vertebrates, and defects in notochord development during embryogenesis...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lien HW, Yang CH, Cheng CH, Hung CC, Liao WH, Hwang PP, Han YS, Huang CJ. A Novel Zinc Finger Protein 219-like (ZNF219L) is Involved in the Regulation of Collagen Type 2 Alpha 1a (col2a1a) Gene Expression in Zebrafish Notochord. Int J Biol Sci. 2013;9(9):872-886. doi:10.7150/ijbs.7126.

A preclinical (188) Re tumor therapeutic investigation using MORF/cMORF pretargeting and an antiTAG-72 antibody CC49

Authors:
Liu G, Dou S, Baker S, Akalin A, Cheng D, Chen L, Rusckowski M, Hnatowich DJ
Citation:
Cancer Biol Ther. 2010 Oct 15;10(8):767-74. doi: 10.4161/cbt.10.8.12879
Epub:
Not Epub
Abstract:
The utility of MORF/cMORF pretargeting for the radiotherapy of cancer requires further validation in tumored mice before...
Delivery Method:
Injection
Organism or Cell Type:
mice
Citation Extract:
Liu G, Dou S, Baker S, Akalin A, Cheng D, Chen L, Rusckowski M, Hnatowich DJ. A preclinical (188) Re tumor therapeutic investigation using MORF/cMORF pretargeting and an antiTAG-72 antibody CC49. Cancer Biol Ther. 2010 Oct 15;10(8):767-74. doi: 10.4161/cbt.10.8.12879.

A Variant of Fibroblast Growth Factor Receptor 2 (Fgfr2) Regulates Left-Right Asymmetry in Zebrafish

Authors:
Liu DW, Hsu CH, Tsai SM, Hsiao CD, Wang WP
Citation:
PLoS ONE. 2011;6(7): e21793. doi:10.1371/journal.pone.0021793
Epub:
Not Epub
Abstract:
Many organs in vertebrates are left-right asymmetrical located. For example, liver is at the right side and stomach is at the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu DW, Hsu CH, Tsai SM, Hsiao CD, Wang WP. A Variant of Fibroblast Growth Factor Receptor 2 (Fgfr2) Regulates Left-Right Asymmetry in Zebrafish. PLoS ONE. 2011;6(7): e21793. doi:10.1371/journal.pone.0021793.

A Y-90 labeled phosphorodiamidate morpholino oligomer for pretargeting radiotherapy

Authors:
Liu G, Dou S, Liu Y, Wang Y, Rusckowski M, Hnatowich D
Citation:
Bioconjug Chem. 2011 Dec 21;22(12):2539-45. doi: 10.1021/bc200366t. Epub 2011 Nov 3
Epub:
Not Epub
Abstract:
While Re-188 has been used successfully in mice for tumor radiotherapy by MORF/cMORF pretargeting, previous radiolabeling of...
Delivery Method:
Injection
Organism or Cell Type:
mice
Citation Extract:
Liu G, Dou S, Liu Y, Wang Y, Rusckowski M, Hnatowich D. A Y-90 labeled phosphorodiamidate morpholino oligomer for pretargeting radiotherapy. Bioconjug Chem. 2011 Dec 21;22(12):2539-45. doi: 10.1021/bc200366t. Epub 2011 Nov 3.

A {beta}Pix-Pak2a signaling pathway regulates cerebral vascular stability in zebrafish

Authors:
Liu J, Fraser SD, Faloon PW, Rollins EL, Vom Berg J, Starovic-Subota O, Laliberte AL, Chen JN, Serluca FC, Childs SJ
Citation:
Proc Natl Acad Sci U S A. 2007 Aug 28;104(35):13990-5. Epub 2007 Jun 15
Epub:
Not Epub
Abstract:
The vasculature tailors to the needs of different tissues and organs. Molecular, structural, and functional specializations are...
Organism or Cell Type:
zebrafish
Citation Extract:
Liu J, Fraser SD, Faloon PW, Rollins EL, Vom Berg J, Starovic-Subota O, Laliberte AL, Chen JN, Serluca FC, Childs SJ. A {beta}Pix-Pak2a signaling pathway regulates cerebral vascular stability in zebrafish. Proc Natl Acad Sci U S A. 2007 Aug 28;104(35):13990-5. Epub 2007 Jun 15.

Action of Vitamin D and the Receptor, VDRa, in Calcium Handling in Zebrafish (Danio rerio)

Authors:
Lin CH, Su CH, Tseng DY, Ding FC, Hwang PP
Citation:
PLoS ONE. 2012;7(9):e45650. doi:10.1371/journal.pone.0045650
Epub:
Not Epub
Abstract:
The purpose of the present study was to use zebrafish as a model to investigate how vitamin D and its receptors interact to...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin CH, Su CH, Tseng DY, Ding FC, Hwang PP. Action of Vitamin D and the Receptor, VDRa, in Calcium Handling in Zebrafish (Danio rerio). PLoS ONE. 2012;7(9):e45650. doi:10.1371/journal.pone.0045650.

Adding a clearing agent to pretargeting does not lower the tumor accumulation of the effector as predicted

Authors:
Liu G, Dou S, Chen X, Chen L, Liu X, Rusckowski M, Hnatowich DJ
Citation:
Cancer Biother Radiopharm. 2010 Dec;25(6):757-62. doi: 10.1089/cbr.2010.0800
Epub:
Not Epub
Abstract:
Clearing agents are often used in pretargeting despite the potential for decreased tumor accumulation of the effector. However...
Delivery Method:
Injection
Organism or Cell Type:
mice
Citation Extract:
Liu G, Dou S, Chen X, Chen L, Liu X, Rusckowski M, Hnatowich DJ. Adding a clearing agent to pretargeting does not lower the tumor accumulation of the effector as predicted. Cancer Biother Radiopharm. 2010 Dec;25(6):757-62. doi: 10.1089/cbr.2010.0800.

An experimental and theoretical evaluation of the influence of pretargeting antibody on the tumor accumulation of effector

Authors:
Liu G, Dou S, Rusckowski M, Hnatowich DJ
Citation:
Mol Cancer Ther. 2008 May;7(5):1025-32
Epub:
Not Epub
Abstract:
In treating tumors by pretargeting, the antitumor antibody and the cytotoxic effector (e.g., toxins and radioactivity) are...
Citation Extract:
Liu G, Dou S, Rusckowski M, Hnatowich DJ. An experimental and theoretical evaluation of the influence of pretargeting antibody on the tumor accumulation of effector. Mol Cancer Ther. 2008 May;7(5):1025-32.

Analysis of thrombocyte development in CD41-GFP transgenic zebrafish

Authors:
Lin HF, Traver D, Zhu H, Dooley K, Paw BH, Zon LI, Handin RI
Citation:
Blood. 2005 Dec 1;106(12):3803-10. Epub 2005 Aug 11.
Epub:
Not Epub
Abstract:
Thrombocytes are the nucleated equivalent of platelets in non-mammalian vertebrates like the zebrafish, Danio rerio. We have...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin HF, Traver D, Zhu H, Dooley K, Paw BH, Zon LI, Handin RI. Analysis of thrombocyte development in CD41-GFP transgenic zebrafish. Blood. 2005 Dec 1;106(12):3803-10. Epub 2005 Aug 11..

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