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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Long-term systemic administration of unconjugated morpholino oligomers for therapeutic expression of dystrophin by exon skipping in skeletal muscle: implications for cardiac muscle integrity
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Citation:
Nucleic Acid Ther. 2011 Aug;21(4):293-8 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is a lethal X-linked inherited disease caused by mutations in the dystrophin gene and... Delivery Method:
Injection Organism or Cell Type:
mice, mdx Citation Extract: Malerba A, Boldrin L, Dickson G. Long-term systemic administration of unconjugated morpholino oligomers for therapeutic expression of dystrophin by exon skipping in skeletal muscle: implications for cardiac muscle integrity. Nucleic Acid Ther. 2011 Aug;21(4):293-8. |
Loss of p53 synthesis in zebrafish tumors with ribosomal protein gene mutations
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Citation:
Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10408-13. Epub 2008 Jul 18 Epub:
Not Epub Abstract:
Zebrafish carrying heterozygous mutations for 17 different ribosomal protein (rp) genes are prone to developing malignant... Organism or Cell Type:
zebrafish Citation Extract: MacInnes AW, Amsterdam A, Whittaker CA, Hopkins N, Lees JA. Loss of p53 synthesis in zebrafish tumors with ribosomal protein gene mutations. Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10408-13. Epub 2008 Jul 18. |
Lowe syndrome: Between primary cilia assembly and Rac1-mediated membrane remodeling
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Citation:
Commun Integr Biol. 2012 Nov 1;5(6):641-4. doi: 10.4161/cib.21952 Epub:
Not Epub Abstract:
Lowe syndrome (LS) is a lethal X-linked genetic disease caused by functional deficiencies of the phosphatidlyinositol 5-... Organism or Cell Type:
zebrafish Citation Extract: Madhivanan K, Mukherjee D, Aguilar RC. Lowe syndrome: Between primary cilia assembly and Rac1-mediated membrane remodeling. Commun Integr Biol. 2012 Nov 1;5(6):641-4. doi: 10.4161/cib.21952. |
Maternally-Recruited DCP1A and DCP2 Contribute to Messenger RNA Degradation During Oocyte Maturation and Genome Activation in Mouse
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Citation:
Biol Reprod. 2012 Nov 7. [Epub ahead of print] Epub:
Not Epub Abstract:
The oocyte-to-zygote transition entails transforming a highly differentiated oocyte into totipotent blastomeres and represents... Organism or Cell Type:
mouse oocytes Citation Extract: Ma J, Flemr M, Strnad H, Svoboda P, Schultz RM. Maternally-Recruited DCP1A and DCP2 Contribute to Messenger RNA Degradation During Oocyte Maturation and Genome Activation in Mouse. Biol Reprod. 2012 Nov 7. [Epub ahead of print]. |
Megalencephalic leukoencephalopathy with subcortical cysts type 1 (MLC1) due to a homozygous deep intronic splicing mutation (c.895-226T>G) abrogated in vitro using an antisense morpholino oligonucleotide
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Citation:
Neurogenetics. 2012 May 3. [Epub ahead of print] Epub:
Not Epub Abstract:
Megalencephalic leukoencephalopathy with subcortical cysts is an autosomal recessive disease characterized by early onset... Organism or Cell Type:
cell culture Citation Extract: Mancini C, Vaula G, Scalzitti L, Cavalieri S, Bertini E, Aiello C, Lucchini C, Gatti RA, Brussino A, Brusco A. Megalencephalic leukoencephalopathy with subcortical cysts type 1 (MLC1) due to a homozygous deep intronic splicing mutation (c.895-226T>G) abrogated in vitro using an antisense morpholino oligonucleotide. Neurogenetics. 2012 May 3. [Epub ahead of print]. |
Methionine aminopeptidase 2 is required for hematopoietic stem cell initiation and proliferation
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Citation:
Blood. 2011 Epub ahead of print] doi:10.1182/blood-2011-04-350173 Epub:
Not Epub Abstract:
In a chemical screening, we tested the anti-angiogenic effects of fumagillin derivatives and identified fumagillin as an... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Ma AC, Fung TK, Lin RHC, Chung MIS, Yang D, Ekker SC, Leung AYH. Methionine aminopeptidase 2 is required for hematopoietic stem cell initiation and proliferation. Blood. 2011 Epub ahead of print] doi:10.1182/blood-2011-04-350173. |
Midkine-A functions upstream of Id2a to regulate cell cycle kinetics in the developing vertebrate retina
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Citation:
Neural Dev. 2012;7(33). doi:10.1186/1749-8104-7-33 Epub:
Not Epub Abstract:
Background Midkine is a small heparin binding growth factor expressed in numerous tissues during development. The unique... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Luo J, Uribe RA, Hayton S, Calinescu A-A, Gross JM, Hitchcock PF. Midkine-A functions upstream of Id2a to regulate cell cycle kinetics in the developing vertebrate retina. Neural Dev. 2012;7(33). doi:10.1186/1749-8104-7-33. |
Mitogen-activated Protein Kinase p38 Regulates the Wnt/Cyclic GMP/Ca2+ Non-canonical Pathway
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Citation:
J Biol Chem. 2007 Sep 28;282(39):28980-90. Epub 2007 Aug 7 Epub:
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The non-canonical Wnt/cyclic GMP/Ca(2+)/NF-AT pathway operates via Frizzled-2, a member of the superfamily of G protein-coupled... Organism or Cell Type:
cell culture: mouse F9 cells Citation Extract: Ma L, Wang HY. Mitogen-activated Protein Kinase p38 Regulates the Wnt/Cyclic GMP/Ca2+ Non-canonical Pathway. J Biol Chem. 2007 Sep 28;282(39):28980-90. Epub 2007 Aug 7. |
Molecular identity of the late sodium current in adult dog cardiomyocytes identified by Nav1.5-antisense inhibition
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Citation:
Am J Physiol Heart Circ Physiol. 2008 Aug;295(2):H667-76. Epub 2008 Jun 13. Epub:
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Late Na(+) current (INaL) is a major component of the action potential plateau in human and canine myocardium. Since INaL is... Delivery Method:
Special Delivery Organism or Cell Type:
cell culture: adult dog ventricular cardiomyocytes Citation Extract: Maltsev VA, Kyle JJ, Mishra S, Undrovinas AA. Molecular identity of the late sodium current in adult dog cardiomyocytes identified by Nav1.5-antisense inhibition. Am J Physiol Heart Circ Physiol. 2008 Aug;295(2):H667-76. Epub 2008 Jun 13.. |
Mouse Emi2 is required to enter meiosis II by reestablishing cyclin B1 during interkinesis
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Citation:
J Cell Biol. 2006 Sep 11;174(6):791-801 Epub:
Not Epub Abstract:
During interkinesis, a metaphase II (MetII) spindle is built immediately after the completion of meiosis I. Oocytes then remain... Delivery Method:
Microinjection Organism or Cell Type:
mouse oocytes Citation Extract: Madgwick S, Hansen DV, Levasseur M, Jackson PK, Jones KT. Mouse Emi2 is required to enter meiosis II by reestablishing cyclin B1 during interkinesis. J Cell Biol. 2006 Sep 11;174(6):791-801. |