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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
Functional modeling in zebrafish demonstrates that the atrial-fibrillation-associated gene GREM2 regulates cardiac laterality, cardiomyocyte differentiation and atrial rhythm
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Citation:
Dis Model Mech. 2012 Dec 7. [Epub ahead of print] Epub:
Not Epub Abstract:
Atrial fibrillation (AF) is the most common cardiac arrhythmia and carries a significant risk of stroke and heart failure. The... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Müller II, Melville DB, Tanwar V, Rybski WM, Mukherjee A, Shoemaker BM, Wang WD, Schoenhard JA, Roden DM, Darbar D, Knapik EW, Hatzopoulos AK. Functional modeling in zebrafish demonstrates that the atrial-fibrillation-associated gene GREM2 regulates cardiac laterality, cardiomyocyte differentiation and atrial rhythm. Dis Model Mech. 2012 Dec 7. [Epub ahead of print]. |
Gain- and loss-of-function in chick embryos by electroporation.
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Citation:
Mech Dev. 2004 Sep;121(9):1137-43. Epub:
Not Epub Abstract:
It remained very difficult to manipulate gene expression in chick embryos until the advent of in ovo electroporation which... Delivery Method:
Electroporation Organism or Cell Type:
chick embryo Citation Extract: Nakamura H, Katahira T, Sato T, Watanabe Y, Funahashi J.. Gain- and loss-of-function in chick embryos by electroporation.. Mech Dev. 2004 Sep;121(9):1137-43.. |
Gene Knockdowns in Adult Animals: PPMOs and Vivo-Morpholinos
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Citation:
Molecules. 2009 Mar 25;14(3):1304-23 Epub:
Not Epub Abstract:
Antisense molecules do not readily cross cell membranes. This has limited the use of antisense to systems where techniques have... Citation Extract: Moulton JD, Jiang S. Gene Knockdowns in Adult Animals: PPMOs and Vivo-Morpholinos. Molecules. 2009 Mar 25;14(3):1304-23. |
Glucocorticoid Receptor Signaling Is Essential for Mesoderm Formation and Muscle Development in Zebrafish
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Citation:
Endocrinology. 2011;[Epub ahead of print] doi:10.1210/en.2011-1559 Epub:
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Glucocorticoid receptor (GR) signaling is thought to play a key role in embryogenesis, but its specific developmental effects... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Nesan D, Kamkar M, Burrows J, Scott IC, Marsden M, Vijayan MM. Glucocorticoid Receptor Signaling Is Essential for Mesoderm Formation and Muscle Development in Zebrafish. Endocrinology. 2011;[Epub ahead of print] doi:10.1210/en.2011-1559 . |
Guidance of mesoderm cell migration in the Xenopus gastrula requires PDGF signaling
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Citation:
Development. 2004 Jun;131(11):2727-36. Epub 2004 May 5 Epub:
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In vertebrates, PDGFA and its receptor, PDGFRalpha, are expressed in the early embryo. Impairing their function causes an array... Organism or Cell Type:
Xenopus Citation Extract: Nagel M, Tahinci E, Symes K, Winklbauer R. Guidance of mesoderm cell migration in the Xenopus gastrula requires PDGF signaling. Development. 2004 Jun;131(11):2727-36. Epub 2004 May 5. |
Hes6 Is Required for the Neurogenic Activity of Neurogenin and NeuroD
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Citation:
PLoS ONE. 2011;6(11):e27880. doi:10.1371/journal.pone.0027880 Epub:
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In the embryonic neural plate, a subset of precursor cells with neurogenic potential differentiates into neurons. This process... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Murai K, Philpott A, Jones PH. Hes6 Is Required for the Neurogenic Activity of Neurogenin and NeuroD. PLoS ONE. 2011;6(11):e27880. doi:10.1371/journal.pone.0027880. |
HIF-1alpha signaling upstream of Nkx2.5 is required for cardiac development in xenopus
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Citation:
J Biol Chem. 2008 Apr 25;283(17):11841-9. Epub 2008 Feb 25. Epub:
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HIF-1alpha is originally identified as a transcription factor that activates gene expression in response to hypoxia. In... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Nagao K, Taniyama Y, Kietzmann T, Doi T, Komuro I, Morishita R. HIF-1alpha signaling upstream of Nkx2.5 is required for cardiac development in xenopus. J Biol Chem. 2008 Apr 25;283(17):11841-9. Epub 2008 Feb 25.. |
Hippo signaling components, Mst1 and Mst2, act as a switch between self-renewal and differentiation in Xenopus hematopoietic and endothelial progenitors
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Citation:
Int J Dev Biol. 2013;57(5):407-14. doi: 10.1387/ijdb.130010st. Epub:
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Hippo signaling is a conserved pathway that regulates cell proliferation and organ size control. Mst1 and Mst2 were identified... Delivery Method:
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Xenopus tropicalis Citation Extract: Nejigane S, Takahashi S, Haramoto Y, Michiue T, Asashima M. Hippo signaling components, Mst1 and Mst2, act as a switch between self-renewal and differentiation in Xenopus hematopoietic and endothelial progenitors. Int J Dev Biol. 2013;57(5):407-14. doi: 10.1387/ijdb.130010st.. |
Identification and angiogenic role of the novel tumor endothelial marker CLEC14A
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Citation:
Oncogene. 2012 Jan 19;31(3):293-305. doi: 10.1038/onc.2011.233. Epub 2011 Jun 27 Epub:
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Tumor endothelial markers (TEMs) that are highly expressed in human tumor vasculature compared with vasculature in normal... Delivery Method:
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zebrafish Citation Extract: Mura M, Swain RK, Zhuang X, Vorschmitt H, Reynolds G, Durant S, Beesley JF, Herbert JM, Sheldon H, Andre M, Sanderson S, Glen K, Luu NT, McGettrick HM, Antczak P, Falciani F, Nash GB, Nagy ZS, Bicknell R. Identification and angiogenic role of the novel tumor endothelial marker CLEC14A. Oncogene. 2012 Jan 19;31(3):293-305. doi: 10.1038/onc.2011.233. Epub 2011 Jun 27. |
Identification and characterization of Veph, a novel gene encoding a PH domain-containing protein expressed in the developing central nervous system of vertebrates
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Citation:
Biochimie. 2004 Aug;86(8):523-31 Epub:
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We isolated Veph, a novel gene encoding a pleckstrin homology (PH) domain-containing protein from a mouse. Veph was strongly... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Muto E, Tabata Y, Taneda T, Aoki Y, Muto A, Arai K, Watanabe S. Identification and characterization of Veph, a novel gene encoding a PH domain-containing protein expressed in the developing central nervous system of vertebrates. Biochimie. 2004 Aug;86(8):523-31. |