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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Altering presenilin gene activity in zebrafish embryos causes changes in expression of genes with potential involvement in Alzheimer's disease pathogenesis

Authors:
Newman M, Tucker B, Nornes S, Ward A, Lardelli M
Citation:
J Alzheimers Dis. 2009 Jan;16(1):133-47
Epub:
Not Epub
Abstract:
Aberrant splicing and point mutations in the human presenilin genes, PSEN1 and PSEN2, have been linked to familial forms of...
Organism or Cell Type:
zebrafish
Citation Extract:
Newman M, Tucker B, Nornes S, Ward A, Lardelli M. Altering presenilin gene activity in zebrafish embryos causes changes in expression of genes with potential involvement in Alzheimer's disease pathogenesis. J Alzheimers Dis. 2009 Jan;16(1):133-47.

Antisense Morpholino-Oligomers Directed against the 5' End of the Genome Inhibit Coronavirus Proliferation and Growth

Authors:
Neuman BW, Stein DA, Kroeker AD, Paulino AD, Moulton HM, Iversen PL, Buchmeier MJ
Citation:
J Virol. 2004 Jun;78(11):5891-5899
Epub:
Not Epub
Abstract:
Conjugation of a peptide related to the human immunodeficiency virus type 1 Tat represents a novel method for delivery of...
Delivery Method:
peptide-coupled
Organism or Cell Type:
cell culture: mouse astrocytoma DBT
Citation Extract:
Neuman BW, Stein DA, Kroeker AD, Paulino AD, Moulton HM, Iversen PL, Buchmeier MJ. Antisense Morpholino-Oligomers Directed against the 5' End of the Genome Inhibit Coronavirus Proliferation and Growth. J Virol. 2004 Jun;78(11):5891-5899.

Antisense Targeting of cFLIP Sensitizes Activated T Cells to Undergo Apoptosis and Desensitizes Responses to Contact Dermatitis

Authors:
Mourich DV, Jendrzejewski JL, Marshall NB, Hinrichs DJ, Iversen PL, Brand RM
Citation:
J Invest Dermatol. 2009 Feb 19. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Contact dermatitis is the result of inflammatory responses mediated by hapten-specific activated CD8+ and CD4+ T cells....
Delivery Method:
peptide-coupled
Organism or Cell Type:
mice and cell culture: T cells
Citation Extract:
Mourich DV, Jendrzejewski JL, Marshall NB, Hinrichs DJ, Iversen PL, Brand RM. Antisense Targeting of cFLIP Sensitizes Activated T Cells to Undergo Apoptosis and Desensitizes Responses to Contact Dermatitis. J Invest Dermatol. 2009 Feb 19. [Epub ahead of print].

Antiviral and Neuroprotective Role of Octaguanidinium Dendrimer-Conjugated Morpholino Oligomers in Japanese Encephalitis

Authors:
Nazmi A, Dutta K, Basu A
Citation:
PLoS Negl Trop Dis 2010;4(11): e892. doi:10.1371/journal.pntd.0000892
Epub:
Not Epub
Abstract:
Background Japanese encephalitis (JE), caused by a mosquito-borne flavivirus, is endemic to the entire south-east Asian and...
Citation Extract:
Nazmi A, Dutta K, Basu A. Antiviral and Neuroprotective Role of Octaguanidinium Dendrimer-Conjugated Morpholino Oligomers in Japanese Encephalitis. PLoS Negl Trop Dis 2010;4(11): e892. doi:10.1371/journal.pntd.0000892.

Antizyme targets cyclin D1 for degradation. A novel mechanism for cell growth repression

Authors:
Newman RM, Mobascher A, Mangold U, Koike C, Diah S, Schmidt M, Finley D, Zetter BR
Citation:
J Biol Chem. 2004 Oct 1;279(40):41504-11. Epub 2004 Jul 23
Epub:
Not Epub
Abstract:
Overproduction of the ornithine decarboxylase (ODC) regulatory protein ODC-antizyme has been shown to correlate with cell...
Delivery Method:
Special Delivery
Organism or Cell Type:
Cell culture: Dunning rat prostate carcinoma (AT2.1 cell)
Citation Extract:
Newman RM, Mobascher A, Mangold U, Koike C, Diah S, Schmidt M, Finley D, Zetter BR. Antizyme targets cyclin D1 for degradation. A novel mechanism for cell growth repression. J Biol Chem. 2004 Oct 1;279(40):41504-11. Epub 2004 Jul 23.

Arginine-rich Peptide conjugation to morpholino oligomers: effects on antisense activity and specificity

Authors:
Nelson MH, Stein DA, Kroeker AD, Hatlevig SA, Iversen PL, Moulton HM
Citation:
Bioconjug Chem. 2005 Jul-Aug;16(4):959-66
Epub:
Not Epub
Abstract:
Noncharged antisense compounds, such as phosphorodiamidate morpholino oligomers (PMOs), do not readily enter mammalian cells in...
Delivery Method:
peptide-coupled
Organism or Cell Type:
cell culture: HeLa Antisense Test System, others
Citation Extract:
Nelson MH, Stein DA, Kroeker AD, Hatlevig SA, Iversen PL, Moulton HM. Arginine-rich Peptide conjugation to morpholino oligomers: effects on antisense activity and specificity. Bioconjug Chem. 2005 Jul-Aug;16(4):959-66.

Barcoded DNA-Tag Reporters for Multiplex Cis-Regulatory Analysis

Authors:
Nam J, Davidson EH
Citation:
PLoS ONE. 2012;7(4):e35934. doi:10.1371/journal.pone.0035934
Epub:
Not Epub
Abstract:
Cis-regulatory DNA sequences causally mediate patterns of gene expression, but efficient experimental analysis of these control...
Delivery Method:
Microinjection
Organism or Cell Type:
Sea urchins
Citation Extract:
Nam J, Davidson EH. Barcoded DNA-Tag Reporters for Multiplex Cis-Regulatory Analysis. PLoS ONE. 2012;7(4):e35934. doi:10.1371/journal.pone.0035934.

Biogenesis of GPI-anchored proteins is essential for surface expression of sodium channels in zebrafish Rohon-Beard neurons to respond to mechanosensory stimulation

Authors:
Nakano Y, Fujita M, Ogino K, Saint-Amant L, Kinoshita T, Oda Y, Hirata H
Citation:
Development. 2010 Apr 14. [Epub ahead of print]
Epub:
Not Epub
Abstract:
In zebrafish, Rohon-Beard (RB) neurons are primary sensory neurons present during the embryonic and early larval stages. At 2...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nakano Y, Fujita M, Ogino K, Saint-Amant L, Kinoshita T, Oda Y, Hirata H. Biogenesis of GPI-anchored proteins is essential for surface expression of sodium channels in zebrafish Rohon-Beard neurons to respond to mechanosensory stimulation. Development. 2010 Apr 14. [Epub ahead of print].

Calcitonin receptor-like receptor guides arterial differentiation in Zebrafish

Authors:
Nicoli S, Tobia C, Gualandi L, De Sena G, Presta M
Citation:
Blood. 2008 May 15;111(10):4965-72. Epub 2008 Mar 7.
Epub:
Not Epub
Abstract:
Calcitonin receptor-like receptor (crlr) is a major endothelial cell receptor for adrenomedullin, a peptide vasodilator...
Organism or Cell Type:
zebrafish
Citation Extract:
Nicoli S, Tobia C, Gualandi L, De Sena G, Presta M. Calcitonin receptor-like receptor guides arterial differentiation in Zebrafish. Blood. 2008 May 15;111(10):4965-72. Epub 2008 Mar 7..

Caldesmon regulates actin dynamics to influence cranial neural crest migration in Xenopus

Authors:
Nie S, Kee Y, Bronner-Fraser M
Citation:
Mol Biol Cell. 2011 Jul 27. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Caldesmon (CaD) is an important actin modulator that associates with actin filaments to regulate cell morphology and motility....
Organism or Cell Type:
Xenopus
Citation Extract:
Nie S, Kee Y, Bronner-Fraser M. Caldesmon regulates actin dynamics to influence cranial neural crest migration in Xenopus. Mol Biol Cell. 2011 Jul 27. [Epub ahead of print].

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