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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Neural crest specification by noncanonical Wnt signaling and PAR-1

Authors:
Ossipova O, Sokol SY
Citation:
Development. 2011;138:5441-50. doi:10.1242/dev.067280
Epub:
Not Epub
Abstract:
Neural crest (NC) cells are multipotent progenitors that form at the neural plate border, undergo epithelial-mesenchymal...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Ossipova O, Sokol SY. Neural crest specification by noncanonical Wnt signaling and PAR-1. Development. 2011;138:5441-50. doi:10.1242/dev.067280 .

New functions for a vertebrate Rho guanine nucleotide exchange factor in ciliated epithelia

Authors:
Panizzi JR, Jessen JR, Drummond IA, Solnica-Krezel L
Citation:
Development, Mar 2007; 134: 921 - 931.
Epub:
Not Epub
Abstract:
Human ARHGEF11, a PDZ-domain-containing Rho guanine nucleotide exchange factor (RhoGEF), has been studied primarily in tissue...
Organism or Cell Type:
zebrafish
Citation Extract:
Panizzi JR, Jessen JR, Drummond IA, Solnica-Krezel L. New functions for a vertebrate Rho guanine nucleotide exchange factor in ciliated epithelia. Development, Mar 2007; 134: 921 - 931..

NLK positively regulates Wnt/β-catenin signalling by phosphorylating LEF1 in neural progenitor cells

Authors:
Ota S, Ishitani S, Shimizu N, Matsumoto K, Itoh M, Ishitani T
Citation:
EMBO J. 2012;[Epub ahead of print] doi:10.1038/emboj.2012.46
Epub:
Not Epub
Abstract:
Nemo-like kinase (NLK/Nlk) is an evolutionarily conserved protein kinase involved in Wnt/β-catenin signalling. However, the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ota S, Ishitani S, Shimizu N, Matsumoto K, Itoh M, Ishitani T. NLK positively regulates Wnt/β-catenin signalling by phosphorylating LEF1 in neural progenitor cells. EMBO J. 2012;[Epub ahead of print] doi:10.1038/emboj.2012.46.

Notch signalling is required for the formation of structurally stable muscle fibres in zebrafish

Authors:
Pascoal S, Esteves de Lima J, Leslie JD, Hughes SM, Saúde L
Citation:
PLoS One. 2013 Jun 28;8(6):e68021. doi: 10.1371/journal.pone.0068021. Print 2013.
Epub:
Not Epub
Abstract:
BACKGROUND: Accurate regulation of Notch signalling is central for developmental processes in a variety of tissues, but its...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pascoal S, Esteves de Lima J, Leslie JD, Hughes SM, Saúde L. Notch signalling is required for the formation of structurally stable muscle fibres in zebrafish. PLoS One. 2013 Jun 28;8(6):e68021. doi: 10.1371/journal.pone.0068021. Print 2013..

Novel Chemical Suppressors of Long QT Syndrome Identified by an In Vivo Functional Screen

Authors:
Peal DS, Mills RW, Lynch SN, Mosley JM, Lim E, Ellinor PT, January CT, Peterson RT, Milan DJ
Citation:
Circulation. 2011 Jan 4;123(1):23-30. Epub 2010 Nov 15.
Epub:
Not Epub
Abstract:
Background- Genetic long QT (LQT) syndrome is a life-threatening disorder caused by mutations that result in prolongation of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Peal DS, Mills RW, Lynch SN, Mosley JM, Lim E, Ellinor PT, January CT, Peterson RT, Milan DJ. Novel Chemical Suppressors of Long QT Syndrome Identified by an In Vivo Functional Screen. Circulation. 2011 Jan 4;123(1):23-30. Epub 2010 Nov 15..

Novel gene ashwin functions in Xenopus cell survival and anteroposterior patterning

Authors:
Patil SS, Alexander TB, Uzman JA, Lou CH, Gohil H, Sater AK
Citation:
Dev Dyn. 2006 May 5;235(7):1895-1907 [Epub ahead of print]
Epub:
Not Epub
Abstract:
The novel gene ashwin was isolated in a differential display screen for genes activated or up-regulated early in neural...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Patil SS, Alexander TB, Uzman JA, Lou CH, Gohil H, Sater AK. Novel gene ashwin functions in Xenopus cell survival and anteroposterior patterning. Dev Dyn. 2006 May 5;235(7):1895-1907 [Epub ahead of print].

Oligodendrocyte specification in zebrafish requires notch-regulated cyclin-dependent kinase inhibitor function

Authors:
Park HC, Boyce J, Shin J, Appel B
Citation:
J Neurosci. 2005 Jul 20;25(29):6836-44
Epub:
Not Epub
Abstract:
Cyclin-dependent kinase inhibitors (Cdkis) influence both cell-cycle progression and differentiation of neural cells. However,...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Park HC, Boyce J, Shin J, Appel B. Oligodendrocyte specification in zebrafish requires notch-regulated cyclin-dependent kinase inhibitor function. J Neurosci. 2005 Jul 20;25(29):6836-44.

p38α MAPK is a MTOC-associated protein regulating spindle assembly, spindle length and accurate chromosome segregation during mouse oocyte meiotic maturation

Authors:
Ou XH, Li S, Xu BZ, Wang ZB, Quan S, Li M, Zhang QH, Ouyang YC, Schatten H, Xing FQ, Sun QY
Citation:
Cell Cycle. 2010 Oct 20;9(20). [Epub ahead of print]
Epub:
Not Epub
Abstract:
P38αMAPK (p38α) is usually activated in response to various stresses and plays a role in the inhibition of cell proliferation...
Delivery Method:
Microinjection
Organism or Cell Type:
mouse oocytes
Citation Extract:
Ou XH, Li S, Xu BZ, Wang ZB, Quan S, Li M, Zhang QH, Ouyang YC, Schatten H, Xing FQ, Sun QY. p38α MAPK is a MTOC-associated protein regulating spindle assembly, spindle length and accurate chromosome segregation during mouse oocyte meiotic maturation. Cell Cycle. 2010 Oct 20;9(20). [Epub ahead of print].

PAR-1 phosphorylates Mind bomb to promote vertebrate neurogenesis

Authors:
Ossipova O, Ezan J, Sokol SY
Citation:
Dev Cell. 2009 Aug;17(2):222-33
Epub:
Not Epub
Abstract:
Generation of neurons in the vertebrate central nervous system requires a complex transcriptional regulatory network and...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Ossipova O, Ezan J, Sokol SY. PAR-1 phosphorylates Mind bomb to promote vertebrate neurogenesis. Dev Cell. 2009 Aug;17(2):222-33.

PAR1 specifies ciliated cells in vertebrate ectoderm downstream of aPKC

Authors:
Ossipova O, Tabler J, Green JB, Sokol SY
Citation:
Development. 2007 Dec;134(23):4297-306
Epub:
Not Epub
Abstract:
Partitioning-defective 1 (PAR1) and atypical protein kinase C (aPKC) are conserved serine/threonine protein kinases implicated...
Organism or Cell Type:
Xenopus
Citation Extract:
Ossipova O, Tabler J, Green JB, Sokol SY. PAR1 specifies ciliated cells in vertebrate ectoderm downstream of aPKC. Development. 2007 Dec;134(23):4297-306.

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