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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Deep intron elements mediate nested splicing events at consecutive AG-dinucleotides to regulate alternative 3' splice site choice in vertebrate 4.1 genes

Authors:
Parra MK, Gallagher TL, Amacher SL, Mohandas N, Conboy JG
Citation:
Mol Cell Biol. 2012 Apr 2. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Distal intraexon (iE) regulatory elements in 4.1R pre-mRNA govern 3' splice site choice at exon 2 (E2) via nested splicing...
Delivery Method:
Vivo-Morpholino in mouse, bare Morpholino in zebrafish
Organism or Cell Type:
Mice and zebrafish
Citation Extract:
Parra MK, Gallagher TL, Amacher SL, Mohandas N, Conboy JG. Deep intron elements mediate nested splicing events at consecutive AG-dinucleotides to regulate alternative 3' splice site choice in vertebrate 4.1 genes. Mol Cell Biol. 2012 Apr 2. [Epub ahead of print].

Delivery of Morpholino Antisense Oligos into Mouse and Monkey Ovarian Follicles

Authors:
Patta M, Hanna C, Jensen J, Wu X
Citation:
Biology of Reproduction 2009;81:344
Epub:
Not Epub
Abstract:
To test the feasibility of in vivo gene knockdown in the mammalian ovary, we performed in vitro delivery of Morpholino...
Delivery Method:
Endo-Porter
Organism or Cell Type:
rhesus macaques and mice
Citation Extract:
Patta M, Hanna C, Jensen J, Wu X. Delivery of Morpholino Antisense Oligos into Mouse and Monkey Ovarian Follicles. Biology of Reproduction 2009;81:344.

Developmental expression and regulation of the chemokine CXCL14 in Xenopus

Authors:
Park BY, Hong CS, Sohail FA, Saint-Jeannet JP
Citation:
Int J Dev Biol. 2009;53(4):535-40
Epub:
Not Epub
Abstract:
Chemokines are a family of proteins originally identified for their activity promoting the recruitment of leukocytes to...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Park BY, Hong CS, Sohail FA, Saint-Jeannet JP. Developmental expression and regulation of the chemokine CXCL14 in Xenopus. Int J Dev Biol. 2009;53(4):535-40.

Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells

Authors:
Park TJ, Mitchell BJ, Abitua PB, Kintner C, Wallingford JB
Citation:
Nat Genet. 2008 Jul;40(7):871-9. Epub 2008 Jun 15
Epub:
Not Epub
Abstract:
The planar cell polarity (PCP) signaling system governs many aspects of polarized cell behavior. Here, we use an in vivo model...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Park TJ, Mitchell BJ, Abitua PB, Kintner C, Wallingford JB. Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells. Nat Genet. 2008 Jul;40(7):871-9. Epub 2008 Jun 15.

Distinct enhancers of ptf1a mediate specification and expansion of ventral pancreas in zebrafish

Authors:
Pashos E, Tae Park J, Leach S, Fisher S
Citation:
Dev Biol. 2013 Jul 20. doi:pii: S0012-1606(13)00379-5. 10.1016/j.ydbio.2013.07.011. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Development of the pancreas and cerebellum require Pancreas-specific transcription factor-1a (Ptf1a), which encodes a subunit...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pashos E, Tae Park J, Leach S, Fisher S. Distinct enhancers of ptf1a mediate specification and expansion of ventral pancreas in zebrafish. Dev Biol. 2013 Jul 20. doi:pii: S0012-1606(13)00379-5. 10.1016/j.ydbio.2013.07.011. [Epub ahead of print].

Distinct Neuroblastoma-associated Alterations of PHOX2B Impair Sympathetic Neuronal Differentiation in Zebrafish Models

Authors:
Pei D, Luther W, Wang W, Paw BH, Stewart RA, George RE
Citation:
PLoS Genet. 2013;9(6):e1003533. doi:10.1371/journal.pgen.1003533
Epub:
Not Epub
Abstract:
Heterozygous germline mutations and deletions in PHOX2B, a key regulator of autonomic neuron development, predispose to...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pei D, Luther W, Wang W, Paw BH, Stewart RA, George RE. Distinct Neuroblastoma-associated Alterations of PHOX2B Impair Sympathetic Neuronal Differentiation in Zebrafish Models. PLoS Genet. 2013;9(6):e1003533. doi:10.1371/journal.pgen.1003533.

Distinct PAR-1 proteins function in different branches of Wnt signaling during vertebrate development

Authors:
Ossipova O, Dhawan S, Sokol S, Green JB
Citation:
Dev Cell. 2005 Jun;8(6):829-41
Epub:
Not Epub
Abstract:
The kinase PAR-1 plays conserved roles in cell polarity. PAR-1 has also been implicated in axis establishment in C. elegans and...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Ossipova O, Dhawan S, Sokol S, Green JB. Distinct PAR-1 proteins function in different branches of Wnt signaling during vertebrate development. Dev Cell. 2005 Jun;8(6):829-41.

Ectopic EphA4 receptor induces posterior protrusions via FGF signaling in Xenopus embryos

Authors:
Park EK, Warner N, Bong YS, Stapleton D, Maeda R, Pawson T, Daar IO
Citation:
Mol Biol Cell. 2004 Apr;15(4):1647-55.
Epub:
Not Epub
Abstract:
The Eph family of receptor tyrosine kinases regulates numerous biological processes. To examine the biochemical and...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Park EK, Warner N, Bong YS, Stapleton D, Maeda R, Pawson T, Daar IO. Ectopic EphA4 receptor induces posterior protrusions via FGF signaling in Xenopus embryos. Mol Biol Cell. 2004 Apr;15(4):1647-55..

Efficient Delivery of DNA and Morpholinos into Mouse Preimplantation Embryos by Electroporation

Authors:
Peng H, Wu Y, Zhang Y
Citation:
PLoS ONE. 2012;7(8):e43748. doi:10.1371/journal.pone.0043748
Epub:
Not Epub
Abstract:
Mouse preimplantation development is characterized by three major transitions and two lineage segregations. Each transition or...
Delivery Method:
Electroporation
Organism or Cell Type:
mouse embryos,preimplantation
Citation Extract:
Peng H, Wu Y, Zhang Y. Efficient Delivery of DNA and Morpholinos into Mouse Preimplantation Embryos by Electroporation. PLoS ONE. 2012;7(8):e43748. doi:10.1371/journal.pone.0043748.

Efficient in vivo manipulation of alternative pre-mRNA splicing events using antisense morpholinos in mice

Authors:
Parra MK, Gee S, Mohandas N, Conboy JG
Citation:
J Biol Chem. 2011 Feb 25;286(8):6033-9. Epub 2010 Dec 14
Epub:
Not Epub
Abstract:
Mammalian pre-mRNA alternative splicing mechanisms are typically studied using artificial minigenes in cultured cells,...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Parra MK, Gee S, Mohandas N, Conboy JG. Efficient in vivo manipulation of alternative pre-mRNA splicing events using antisense morpholinos in mice. J Biol Chem. 2011 Feb 25;286(8):6033-9. Epub 2010 Dec 14.

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