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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

An actin cytoskeleton with evolutionarily conserved functions in the absence of canonical actin-binding proteins

Authors:
Paredez AR, Assaf ZJ, Sept D, Timofejeva L, Dawson SC, Wang CJ, Cande WZ
Citation:
Proc Natl Acad Sci U S A. 2011 Apr 12;108(15):6151-6. Epub 2011 Mar 28.
Epub:
Not Epub
Abstract:
Giardia intestinalis, a human intestinal parasite and member of what is perhaps the earliest-diverging eukaryotic lineage,...
Delivery Method:
Electroporation
Organism or Cell Type:
Giardia intestinalis
Citation Extract:
Paredez AR, Assaf ZJ, Sept D, Timofejeva L, Dawson SC, Wang CJ, Cande WZ. An actin cytoskeleton with evolutionarily conserved functions in the absence of canonical actin-binding proteins. Proc Natl Acad Sci U S A. 2011 Apr 12;108(15):6151-6. Epub 2011 Mar 28..

An antisense oligonucleotide to 1-cys peroxiredoxin causes lipid peroxidation and apoptosis in lung epithelial cells

Authors:
Pak JH, Manevich Y, Kim HS, Feinstein SI, Fisher AB
Citation:
J Biol Chem. 2002 Dec 20;277(51):49927-34. Epub 2002 Oct 07
Epub:
Not Epub
Abstract:
1-cys peroxiredoxin (1-cysPrx), a member of the peroxiredoxin superfamily, reduces phospholipid hydroperoxides as well as...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: L2 cells
Citation Extract:
Pak JH, Manevich Y, Kim HS, Feinstein SI, Fisher AB. An antisense oligonucleotide to 1-cys peroxiredoxin causes lipid peroxidation and apoptosis in lung epithelial cells. J Biol Chem. 2002 Dec 20;277(51):49927-34. Epub 2002 Oct 07.

An early requirement for maternal FoxH1 during zebrafish gastrulation

Authors:
Pei W, Noushmehr H, Costa J, Ouspenskaia MV, Elkahloun AG, Feldman B
Citation:
Dev Biol. 2007 Oct 1;310(1):10-22. Epub 2007 Jul 19.
Epub:
Not Epub
Abstract:
The Forkhead Box H1 (FoxH1) protein is a co-transcription factor recruited by phosphorylated Smad2 downstream of several...
Organism or Cell Type:
zebrafish
Citation Extract:
Pei W, Noushmehr H, Costa J, Ouspenskaia MV, Elkahloun AG, Feldman B. An early requirement for maternal FoxH1 during zebrafish gastrulation. Dev Biol. 2007 Oct 1;310(1):10-22. Epub 2007 Jul 19..

Basal body stability and ciliogenesis requires the conserved component Poc1

Authors:
Pearson CG, Osborn DP, Giddings TH Jr, Beales PL, Winey M
Citation:
J Cell Biol. 2009 Dec 14;187(6):905-20
Epub:
Not Epub
Abstract:
Centrioles are the foundation for centrosome and cilia formation. The biogenesis of centrioles is initiated by an assembly...
Organism or Cell Type:
zebrafish
Citation Extract:
Pearson CG, Osborn DP, Giddings TH Jr, Beales PL, Winey M. Basal body stability and ciliogenesis requires the conserved component Poc1. J Cell Biol. 2009 Dec 14;187(6):905-20.

Bi-polarized translation of ascidian maternal mRNA determinant pem-1 associated with regulators of the translation machinery on the cortical endoplasmic reticulum (cER)

Authors:
Paix A, Le Nguyen PN, Sardet C
Citation:
Dev Biol. 2011 Jun 23. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Polarized cortical mRNA determinants such as maternal macho-1 and pem-1 in ascidians, like budding yeast mating factor ASH1...
Delivery Method:
Microinjection
Citation Extract:
Paix A, Le Nguyen PN, Sardet C. Bi-polarized translation of ascidian maternal mRNA determinant pem-1 associated with regulators of the translation machinery on the cortical endoplasmic reticulum (cER). Dev Biol. 2011 Jun 23. [Epub ahead of print].

Bves modulates epithelial integrity through an interaction at the tight junction

Authors:
Osler ME, Chang MS, Bader DM
Citation:
J Cell Sci. 2005 Oct 15;118(Pt 20):4667-78. Epub 2005 Sep 27
Epub:
Not Epub
Abstract:
We first identified Bves (blood vessel/epicardial substance) as a transmembrane protein that localized to the lateral...
Organism or Cell Type:
cell culture: polarized epithelial cell lines
Citation Extract:
Osler ME, Chang MS, Bader DM. Bves modulates epithelial integrity through an interaction at the tight junction. J Cell Sci. 2005 Oct 15;118(Pt 20):4667-78. Epub 2005 Sep 27.

Calfacilitin is a calcium channel modulator essential for initiation of neural plate development

Authors:
Papanayotou C, De Almeida I, Liao P, Oliveira NM, Lu SQ, Kougioumtzidou E, Zhu L, Shaw A, Sheng G, Streit A, Yu D, Wah Soong T, Stern CD
Citation:
Nat Commun. 2013;4:1837. doi: 10.1038/ncomms2864
Epub:
Not Epub
Abstract:
Calcium fluxes have been implicated in the specification of the vertebrate embryonic nervous system for some time, but how...
Delivery Method:
Electroporation
Organism or Cell Type:
chick (Gallus gallus)
Citation Extract:
Papanayotou C, De Almeida I, Liao P, Oliveira NM, Lu SQ, Kougioumtzidou E, Zhu L, Shaw A, Sheng G, Streit A, Yu D, Wah Soong T, Stern CD. Calfacilitin is a calcium channel modulator essential for initiation of neural plate development. Nat Commun. 2013;4:1837. doi: 10.1038/ncomms2864.

Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy

Authors:
Otto EA, Hurd TW, Airik R, Chaki M, Zhou W, Stoetzel C, Patil SB, Levy S, Ghosh AK, Murga-Zamalloa CA, van Reeuwijk J, Letteboer SJ, Sang L, Giles RH, Liu Q, Coene KL, Estrada-Cuzcano A, Collin RW, McLaughlin HM, Held S, Kasanuki JM, Ramaswami G, Conte J, Lopez I, Washburn J, Macdonald J, Hu J, Yamashita Y, Maher ER, Guay-Woodford LM, Neumann HP, Obermüller N, Koenekoop RK, Bergmann C, Bei X, Lewis RA, Katsanis N, Lopes V, Williams DS, Lyons RH, Dang CV, Brito DA, Dias MB, Zhang X, Cavalcoli JD, Nürnberg G, Nürnberg P, Pierce EA, Jackson PK, Antignac C, Saunier S, Roepman R, Dollfus H, Khanna H, Hildebrandt F.
Citation:
Nat Genet. 2010 Oct;42(10):840-50. Epub 2010 Sep 12.
Epub:
Not Epub
Abstract:
Nephronophthisis-related ciliopathies (NPHP-RC) are recessive disorders that feature dysplasia or degeneration occurring...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Otto EA, Hurd TW, Airik R, Chaki M, Zhou W, Stoetzel C, Patil SB, Levy S, Ghosh AK, Murga-Zamalloa CA, van Reeuwijk J, Letteboer SJ, Sang L, Giles RH, Liu Q, Coene KL, Estrada-Cuzcano A, Collin RW, McLaughlin HM, Held S, Kasanuki JM, Ramaswami G, Conte J, Lopez I, Washburn J, Macdonald J, Hu J, Yamashita Y, Maher ER, Guay-Woodford LM, Neumann HP, Obermüller N, Koenekoop RK, Bergmann C, Bei X, Lewis RA, Katsanis N, Lopes V, Williams DS, Lyons RH, Dang CV, Brito DA, Dias MB, Zhang X, Cavalcoli JD, Nürnberg G, Nürnberg P, Pierce EA, Jackson PK, Antignac C, Saunier S, Roepman R, Dollfus H, Khanna H, Hildebrandt F. . Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy. Nat Genet. 2010 Oct;42(10):840-50. Epub 2010 Sep 12..

Cardiac and vascular functions of the zebrafish orthologues of the type I neurofibromatosis gene NFI

Authors:
Padmanabhan A, Lee JS, Ismat FA, Lu MM, Lawson ND, Kanki JP, Look AT, Epstein JA
Citation:
Proc Natl Acad Sci U S A. 2009 Dec 4. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Von Recklinghausen neurofibromatosis is a common autosomal dominant genetic disorder characterized by benign and malignant...
Organism or Cell Type:
zebrafish
Citation Extract:
Padmanabhan A, Lee JS, Ismat FA, Lu MM, Lawson ND, Kanki JP, Look AT, Epstein JA. Cardiac and vascular functions of the zebrafish orthologues of the type I neurofibromatosis gene NFI. Proc Natl Acad Sci U S A. 2009 Dec 4. [Epub ahead of print].

CCDC103 mutations cause primary ciliary dyskinesia by disrupting assembly of ciliary dynein arms

Authors:
Panizzi JR, Becker-Heck A, Castleman VH, Al-Mutairi DA, Liu Y, Loges NT, Pathak N, Austin-Tse C, Sheridan E, Schmidts M, Olbrich H, Werner C, Häffner K, Hellman N, Chodhari R, Gupta A, Kramer-Zucker A, Olale F, Burdine RD, Schier AF, O'Callaghan C, Chung EM, Reinhardt R, Mitchison HM, King SM, Omran H, Drummond IA
Citation:
Nat Genet. 2012 May 13. doi: 10.1038/ng.2277. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Cilia are essential for fertilization, respiratory clearance, cerebrospinal fluid circulation and establishing laterality....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Panizzi JR, Becker-Heck A, Castleman VH, Al-Mutairi DA, Liu Y, Loges NT, Pathak N, Austin-Tse C, Sheridan E, Schmidts M, Olbrich H, Werner C, Häffner K, Hellman N, Chodhari R, Gupta A, Kramer-Zucker A, Olale F, Burdine RD, Schier AF, O'Callaghan C, Chung EM, Reinhardt R, Mitchison HM, King SM, Omran H, Drummond IA. CCDC103 mutations cause primary ciliary dyskinesia by disrupting assembly of ciliary dynein arms. Nat Genet. 2012 May 13. doi: 10.1038/ng.2277. [Epub ahead of print].

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