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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12158 scientific papers returned from the database with the search filters currently being used below.
There are 12158 scientific papers returned from the database with the search filters currently being used below.
Zebrafish integrin-linked kinase is required in skeletal muscles for strengthening the integrin-ECM adhesion complex
Citation:
Dev Biol. 2008 Jun 1;318(1):92-101. Epub 2008 Mar 26. Epub:
Not Epub Abstract:
Mechanical instability of skeletal muscle cells is the major cause of congenital muscular dystrophy. Here we show that the... Organism or Cell Type:
zebrafish Citation Extract: Postel R, Vakeel P, Topczewski J, Knöll R, Bakkers J. Zebrafish integrin-linked kinase is required in skeletal muscles for strengthening the integrin-ECM adhesion complex. Dev Biol. 2008 Jun 1;318(1):92-101. Epub 2008 Mar 26.. |
Zebrafish Usher Genes Are Necessary For Retinal Cell Function And Survival
Citation:
Invest. Ophthalmol. Vis. Sci., May 2006; 47: 4556 Epub:
Not Epub Abstract:
Purpose: The developmental specialization and functional activity of both retinal photoreceptor cells and mechanosensory hair... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Phillips J, Westerfield M. Zebrafish Usher Genes Are Necessary For Retinal Cell Function And Survival. Invest. Ophthalmol. Vis. Sci., May 2006; 47: 4556. |
A novel regulatory circuit in base excision repair involving AP endonuclease 1, Creb1 and DNA polymerase beta
Citation:
Nucleic Acids Res. 2011 Apr 1;39(8):3156-65. Epub 2010 Dec 20 Epub:
Not Epub Abstract:
DNA repair is required to maintain genome stability in stem cells and early embryos. At critical junctures, oxidative damage to... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Pei DS, Yang XJ, Liu W, Guikema JE, Schrader CE, Strauss PR. A novel regulatory circuit in base excision repair involving AP endonuclease 1, Creb1 and DNA polymerase beta. Nucleic Acids Res. 2011 Apr 1;39(8):3156-65. Epub 2010 Dec 20. |
Removal of dystroglycan causes severe muscular dystrophy in zebrafish embryos.
Citation:
Development 2002 Jul;129(14):3505-12 Epub:
Not Epub Abstract:
Muscular dystrophy is frequently caused by disruption of the dystrophin-glycoprotein complex (DGC), which links muscle cells to... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Parsons MJ, Campos I, Hirst EM, Stemple DL. Removal of dystroglycan causes severe muscular dystrophy in zebrafish embryos.. Development 2002 Jul;129(14):3505-12. |
A Mechanism Regulating the Onset of Sox2 Expression in the Embryonic Neural Plate
Citation:
PLoS Biol. 2008 Jan 8;6(1):e2 [Epub ahead of print] Epub:
Not Epub Abstract:
In vertebrate embryos, the earliest definitive marker for the neural plate, which will give rise to the entire central nervous... Delivery Method:
Electroporation Organism or Cell Type:
chick embryo Citation Extract: Papanayotou C, Mey A, Birot AM, Saka Y, Boast S, Smith JC, Samarut J, Stern CD. A Mechanism Regulating the Onset of Sox2 Expression in the Embryonic Neural Plate. PLoS Biol. 2008 Jan 8;6(1):e2 [Epub ahead of print]. |
A model of Costeff Syndrome reveals metabolic and protective functions of mitochondrial OPA3
Citation:
Development. 2010 Aug 1;137(15):2587-96 Epub:
Not Epub Abstract:
Costeff Syndrome, which is caused by mutations in the OPTIC ATROPHY 3 (OPA3) gene, is an early-onset syndrome characterized by... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Pei W, Kratz LE, Bernardini I, Sood R, Yokogawa T, Dorward H, Ciccone C, Kelley RI, Anikster Y, Burgess HA, Huizing M, Feldman B. A model of Costeff Syndrome reveals metabolic and protective functions of mitochondrial OPA3. Development. 2010 Aug 1;137(15):2587-96. |
A Model of Glucose-6-Phosphate Dehydrogenase Deficiency in the Zebrafish
Citation:
Exp Hematol. 2013 Apr 16. doi:pii: S0301-472X(13)00124-0. 10.1016/j.exphem.2013.04.002. [Epub ahead of print] Epub:
Not Epub Abstract:
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common genetic defect and enzymopathy worldwide, affecting... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Patrinostro X, Carter ML, Kramer AC, Lund TC. A Model of Glucose-6-Phosphate Dehydrogenase Deficiency in the Zebrafish. Exp Hematol. 2013 Apr 16. doi:pii: S0301-472X(13)00124-0. 10.1016/j.exphem.2013.04.002. [Epub ahead of print]. |
A positive role for the Ku complex in DNA replication following strand break damage in mammals
Citation:
J Biol Chem. 2003 Nov 15 [Epub ahead of print] Epub:
Not Epub Abstract:
Ku70/Ku80 complex is the regulatory subunits of DNA-dependent protein kinase (DNA-PK) and plays an essential role in double... Delivery Method:
Special Delivery Organism or Cell Type:
cell culture: HeLa cells Citation Extract: Park SJ, Ciccone SL, Freie B, Kurimasa A, Chen DJ, Li GC, Clapp DW, Lee SH. A positive role for the Ku complex in DNA replication following strand break damage in mammals. J Biol Chem. 2003 Nov 15 [Epub ahead of print]. |
A simple method for delivering morpholino antisense oligos into the cytoplasm of cells
Citation:
Antisense Nucleic Acid Drug Dev. 1996 Fall;6(3):169-75 Epub:
Not Epub Abstract:
We report a simple and effective means for delivering Morpholino antisense oligos into the cytosol of cultured anchorage-... Delivery Method:
Scrape Delivery Organism or Cell Type:
cell culture: Hela and rat FT02B liver cells Citation Extract: Partridge M, Vincent A, Matthews P, Puma J, Stein D, Summerton J. A simple method for delivering morpholino antisense oligos into the cytoplasm of cells. Antisense Nucleic Acid Drug Dev. 1996 Fall;6(3):169-75. |
A Temporal Chromatin Signature in Human Embryonic Stem Cells Identifies Regulators of Cardiac Development
Citation:
Cell. 2012;[Epub ahead of print] doi:10.1016/j.cell.2012.08.027 Epub:
Not Epub Abstract:
Directed differentiation of human embryonic stem cells (ESCs) into cardiovascular cells provides a model for studying molecular... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Paige SL, Thomas S, Stoick-Cooper CL, Wang H, Maves L, Sandstrom S, Pabon L, Reinecke H, Pratt G, Keller G, Moon RT, Stamatoyannopoulos J, Murry CE. A Temporal Chromatin Signature in Human Embryonic Stem Cells Identifies Regulators of Cardiac Development. Cell. 2012;[Epub ahead of print] doi:10.1016/j.cell.2012.08.027. |