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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Mutations in ISPD cause Walker-Warburg syndrome and defective glycosylation of α-dystroglycan

Authors:
Roscioli T, Kamsteeg EJ, Buysse K, Maystadt I, van Reeuwijk J, van den Elzen C, van Beusekom E, Riemersma M, Pfundt R, Vissers LE, Schraders M, Altunoglu U, Buckley MF, Brunner HG, Grisart B, Zhou H, Veltman JA, Gilissen C, Mancini GM, Delrée P, Willemsen MA, Ramadža DP, Chitayat D, Bennett C, Sheridan E, Peeters EA, Tan-Sindhunata GM, de Die-Smulders CE, Devriendt K, Kayserili H, El-Hashash OA, Stemple DL, Lefeber DJ, Lin YY, van Bokhoven H
Citation:
Nat Genet. 2012 Apr 22. doi: 10.1038/ng.2253. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Walker-Warburg syndrome (WWS) is an autosomal recessive multisystem disorder characterized by complex eye and brain...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Roscioli T, Kamsteeg EJ, Buysse K, Maystadt I, van Reeuwijk J, van den Elzen C, van Beusekom E, Riemersma M, Pfundt R, Vissers LE, Schraders M, Altunoglu U, Buckley MF, Brunner HG, Grisart B, Zhou H, Veltman JA, Gilissen C, Mancini GM, Delrée P, Willemsen MA, Ramadža DP, Chitayat D, Bennett C, Sheridan E, Peeters EA, Tan-Sindhunata GM, de Die-Smulders CE, Devriendt K, Kayserili H, El-Hashash OA, Stemple DL, Lefeber DJ, Lin YY, van Bokhoven H. Mutations in ISPD cause Walker-Warburg syndrome and defective glycosylation of α-dystroglycan. Nat Genet. 2012 Apr 22. doi: 10.1038/ng.2253. [Epub ahead of print].

Mutations in lectin complement pathway genes COLEC11 and MASP1 cause 3MC syndrome

Authors:
Rooryck C, Diaz-Font A, Osborn DP, Chabchoub E, Hernandez-Hernandez V, Shamseldin H, Kenny J, Waters A, Jenkins D, Kaissi AA, Leal GF, Dallapiccola B, Carnevale F, Bitner-Glindzicz M, Lees M, Hennekam R, Stanier P, Burns AJ, Peeters H, Alkuraya FS, Beales
Citation:
Nat Genet. 2011 Jan 23. [Epub ahead of print]
Epub:
Not Epub
Abstract:
3MC syndrome has been proposed as a unifying term encompassing the overlapping Carnevale, Mingarelli, Malpuech and Michels...
Organism or Cell Type:
zebrafish
Citation Extract:
Rooryck C, Diaz-Font A, Osborn DP, Chabchoub E, Hernandez-Hernandez V, Shamseldin H, Kenny J, Waters A, Jenkins D, Kaissi AA, Leal GF, Dallapiccola B, Carnevale F, Bitner-Glindzicz M, Lees M, Hennekam R, Stanier P, Burns AJ, Peeters H, Alkuraya FS, Beales. Mutations in lectin complement pathway genes COLEC11 and MASP1 cause 3MC syndrome. Nat Genet. 2011 Jan 23. [Epub ahead of print].

Nemo-like kinase (NLK) acts downstream of Notch/Delta signalling to downregulate TCF during mesoderm induction in the sea urchin embryo

Authors:
Röttinger E, Croce J, Lhomond G, Besnardeau L, Gache C, Lepage T
Citation:
Development. 2006 Nov;133(21):4341-53
Epub:
Not Epub
Abstract:
Studies in Caenorhabditis elegans and vertebrates have established that the MAP kinase-related protein NLK counteracts Wnt...
Organism or Cell Type:
Sea urchin, Paracentrotus lividus
Citation Extract:
Röttinger E, Croce J, Lhomond G, Besnardeau L, Gache C, Lepage T. Nemo-like kinase (NLK) acts downstream of Notch/Delta signalling to downregulate TCF during mesoderm induction in the sea urchin embryo. Development. 2006 Nov;133(21):4341-53.

Nodal signalling imposes left-right asymmetry upon neurogenesis in the habenular nuclei

Authors:
Roussigné M, Bianco IH, Wilson SW, Blader P
Citation:
Development. 2009 May;136(9):1549-57
Epub:
Not Epub
Abstract:
The habenulae are evolutionarily conserved bilateral nuclei in the epithalamus that relay input from the forebrain to the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Roussigné M, Bianco IH, Wilson SW, Blader P. Nodal signalling imposes left-right asymmetry upon neurogenesis in the habenular nuclei. Development. 2009 May;136(9):1549-57.

p53 activation by knockdown technologies

Authors:
Robu ME, Larson JD, Nasevicius A, Beiraghi S, Brenner C, Farber SA, Ekker SC
Citation:
PLoS Genet. 2007 May 25;3(5):e78. Epub 2007 Apr 10
Epub:
Not Epub
Abstract:
Morpholino phosphorodiamidate antisense oligonucleotides (MOs) and short interfering RNAs (siRNAs) are commonly used platforms...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Robu ME, Larson JD, Nasevicius A, Beiraghi S, Brenner C, Farber SA, Ekker SC. p53 activation by knockdown technologies. PLoS Genet. 2007 May 25;3(5):e78. Epub 2007 Apr 10.

Paladin is an antiphosphatase that regulates neural crest cell formation and migration

Authors:
Roffers-Agarwal J, Hutt KJ, Gammill LS
Citation:
Dev Biol. 2012 Aug 24. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Although a network of transcription factors that specifies neural crest identity in the ectoderm has been defined, expression...
Delivery Method:
Electroporation
Organism or Cell Type:
chick (Gallus gallus)
Citation Extract:
Roffers-Agarwal J, Hutt KJ, Gammill LS. Paladin is an antiphosphatase that regulates neural crest cell formation and migration. Dev Biol. 2012 Aug 24. [Epub ahead of print].

Regulation of actin cytoskeleton architecture by Eps8 and Abi1

Authors:
Roffers-Agarwal J, Xanthos JB, Miller JR
Citation:
BMC Cell Biol. 2005 Oct 14;6:36
Epub:
Not Epub
Abstract:
BACKGROUND: The actin cytoskeleton participates in many fundamental processes including the regulation of cell shape, motility...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Roffers-Agarwal J, Xanthos JB, Miller JR. Regulation of actin cytoskeleton architecture by Eps8 and Abi1. BMC Cell Biol. 2005 Oct 14;6:36.

Repression of Puma by Scratch2 is required for neuronal survival during embryonic development

Authors:
Rodríguez-Aznar E, Nieto MA
Citation:
Cell Death Differ. 2011 Jul;18(7):1196-207. doi: 10.1038/cdd.2010.190. Epub 2011 Jan 21
Epub:
Not Epub
Abstract:
Although Snail factors promote cell survival in development and cancer, the tumor-suppressor p53 promotes apoptosis in response...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rodríguez-Aznar E, Nieto MA. Repression of Puma by Scratch2 is required for neuronal survival during embryonic development. Cell Death Differ. 2011 Jul;18(7):1196-207. doi: 10.1038/cdd.2010.190. Epub 2011 Jan 21.

Reptin and pontin antagonistically regulate heart growth in zebrafish embryos

Authors:
Rottbauer W, Saurin AJ, Lickert H, Shen X, Burns CG, Wo ZG, Kemler R, Kingston R, Wu C, Fishman M
Citation:
Cell 2002 Nov 27;111(5):661-72
Epub:
Not Epub
Abstract:
Organ size is precisely regulated during development, but the control mechanisms remain obscure. We have isolated a mutation in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rottbauer W, Saurin AJ, Lickert H, Shen X, Burns CG, Wo ZG, Kemler R, Kingston R, Wu C, Fishman M. Reptin and pontin antagonistically regulate heart growth in zebrafish embryos. Cell 2002 Nov 27;111(5):661-72.

Repulsive interactions shape the morphologies and functional arrangement of zebrafish peripheral sensory arbors

Authors:
Sagasti A, Guido MR, Raible DW, Schier AF
Citation:
Curr Biol. 2005 May 10;15(9):804-14
Epub:
Not Epub
Abstract:
BACKGROUND: Trigeminal sensory neurons detect thermal and mechanical stimuli in the skin through their elaborately arborized...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sagasti A, Guido MR, Raible DW, Schier AF. Repulsive interactions shape the morphologies and functional arrangement of zebrafish peripheral sensory arbors. Curr Biol. 2005 May 10;15(9):804-14.

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