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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12165 scientific papers returned from the database with the search filters currently being used below.

RNA-Seq analysis in mutant zebrafish reveals role of U1C protein in alternative splicing regulation

Authors:
Rösel TD, Hung LH, Medenbach J, Donde K, Starke S, Benes V, Rätsch G, Bindereif A
Citation:
EMBO J. 2011 May 18;30(10):1965-76. Epub 2011 Apr 5
Epub:
Not Epub
Abstract:
Precise 5' splice-site recognition is essential for both constitutive and regulated pre-mRNA splicing. The U1 small...
Delivery Method:
Electroporation (Amaxa)
Organism or Cell Type:
cell culture: HeLa cells
Citation Extract:
Rösel TD, Hung LH, Medenbach J, Donde K, Starke S, Benes V, Rätsch G, Bindereif A. RNA-Seq analysis in mutant zebrafish reveals role of U1C protein in alternative splicing regulation. EMBO J. 2011 May 18;30(10):1965-76. Epub 2011 Apr 5.

Rod photoreceptors protect from cone degeneration-induced retinal remodeling and restore visual responses in zebrafish

Authors:
Saade CJ, Alvarez-Delfin K, Fadool JM
Citation:
J Neurosci. 2013 Jan 30;33(5):1804-14. doi: 10.1523/JNEUROSCI.2910-12.2013
Epub:
Not Epub
Abstract:
Humans are largely dependent upon cone-mediated vision. However, death or dysfunction of rods, the predominant photoreceptor...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Saade CJ, Alvarez-Delfin K, Fadool JM. Rod photoreceptors protect from cone degeneration-induced retinal remodeling and restore visual responses in zebrafish. J Neurosci. 2013 Jan 30;33(5):1804-14. doi: 10.1523/JNEUROSCI.2910-12.2013.

Roles of brca2 (fancd1) in Oocyte Nuclear Architecture, Gametogenesis, Gonad Tumors, and Genome Stability in Zebrafish

Authors:
Rodríguez-Marí A, Wilson C, Titus TA, Cañestro C, BreMiller RA, Yan YL, Nanda I, Johnston A, Kanki JP, Gray EM, He X, Spitsbergen J, Schindler D, Postlethwait JH
Citation:
PLoS Genet. 2011;7(3): e1001357. doi:10.1371/journal.pgen.1001357
Epub:
Not Epub
Abstract:
Mild mutations in BRCA2 (FANCD1) cause Fanconi anemia (FA) when homozygous, while severe mutations cause common cancers...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rodríguez-Marí A, Wilson C, Titus TA, Cañestro C, BreMiller RA, Yan YL, Nanda I, Johnston A, Kanki JP, Gray EM, He X, Spitsbergen J, Schindler D, Postlethwait JH. Roles of brca2 (fancd1) in Oocyte Nuclear Architecture, Gametogenesis, Gonad Tumors, and Genome Stability in Zebrafish. PLoS Genet. 2011;7(3): e1001357. doi:10.1371/journal.pgen.1001357.

Runx Expression Is Mitogenic and Mutually Linked to Wnt Activity in Blastula-Stage Sea Urchin Embryos

Authors:
Robertson AJ, Coluccio A, Knowlton P, Dickey-Sims C, Coffman JA
Citation:
PLoS ONE. 2008;3(11):e3770. Epub 2008 Nov 20
Epub:
Not Epub
Abstract:
BACKGROUND: The Runt homology domain (Runx) defines a metazoan family of sequence-specific transcriptional regulatory proteins...
Delivery Method:
Microinjection
Organism or Cell Type:
Sea urchin, Strongylocentrotus purpuratus
Citation Extract:
Robertson AJ, Coluccio A, Knowlton P, Dickey-Sims C, Coffman JA. Runx Expression Is Mitogenic and Mutually Linked to Wnt Activity in Blastula-Stage Sea Urchin Embryos. PLoS ONE. 2008;3(11):e3770. Epub 2008 Nov 20.

Scratch2 Prevents Cell Cycle Re-Entry by Repressing miR-25 in Postmitotic Primary Neurons

Authors:
Rodríguez-Aznar E, Barrallo-Gimeno A, Nieto MA
Citation:
J Neurosci. 2013;33(12):5095-5105. doi:10.1523/JNEUROSCI.4459-12.2013
Epub:
Not Epub
Abstract:
During the development of the nervous system the regulation of cell cycle, differentiation, and survival is tightly interlinked...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rodríguez-Aznar E, Barrallo-Gimeno A, Nieto MA. Scratch2 Prevents Cell Cycle Re-Entry by Repressing miR-25 in Postmitotic Primary Neurons. J Neurosci. 2013;33(12):5095-5105. doi:10.1523/JNEUROSCI.4459-12.2013 .

Sea urchin akt activity is Runx-dependent and required for post-cleavage stage cell division

Authors:
Robertson AJ, Coluccio A, Jensen S, Rydlizky K, Coffman JA
Citation:
Biol Open. 2013;[Epub ahead of print] doi:10.1242/bio.20133913
Epub:
Not Epub
Abstract:
In animal development following the initial cleavage stage of embryogenesis, the cell cycle becomes dependent on intercellular...
Delivery Method:
Microinjection
Organism or Cell Type:
Sea urchin, Strongylocentrotus purpuratus
Citation Extract:
Robertson AJ, Coluccio A, Jensen S, Rydlizky K, Coffman JA. Sea urchin akt activity is Runx-dependent and required for post-cleavage stage cell division. Biol Open. 2013;[Epub ahead of print] doi:10.1242/bio.20133913 .

Serine/Threonine kinase Melk regulates proliferation and glial differentiation of retinal progenitor cells

Authors:
Saito R, Nakauchi H, Watanabe S
Citation:
Cancer Sci. 2011 Sep 16. doi: 10.1111/j.1349-7006.2011.02104.x. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Serine/threonine kinase, Melk, was initially cloned in oocytes, but it is expressed in normal tissues and especially in cancer...
Organism or Cell Type:
zebrafish
Citation Extract:
Saito R, Nakauchi H, Watanabe S. Serine/Threonine kinase Melk regulates proliferation and glial differentiation of retinal progenitor cells. Cancer Sci. 2011 Sep 16. doi: 10.1111/j.1349-7006.2011.02104.x. [Epub ahead of print].

Sex Reversal in Zebrafish fancl Mutants Is Caused by Tp53-Mediated Germ Cell Apoptosis

Authors:
Rodríguez-Marí A, Cañestro C, Bremiller RA, Nguyen-Johnson A, Asakawa K, Kawakami K, Postlethwait JH
Citation:
PLoS Genet. 2010 Jul 22;6(7):e1001034
Epub:
Not Epub
Abstract:
The molecular genetic mechanisms of sex determination are not known for most vertebrates, including zebrafish. We identified a...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rodríguez-Marí A, Cañestro C, Bremiller RA, Nguyen-Johnson A, Asakawa K, Kawakami K, Postlethwait JH. Sex Reversal in Zebrafish fancl Mutants Is Caused by Tp53-Mediated Germ Cell Apoptosis. PLoS Genet. 2010 Jul 22;6(7):e1001034.

Sinup, a novel Siaz-interacting nuclear protein, modulates neural plate formation in the zebrafish embryos

Authors:
Ro H, Won M, Lee SU, Kim KE, Huh TL, Kim CH, Rhee M
Citation:
Biochem Biophys Res Commun. 2005 Jul 15;332(4):993-1003.
Epub:
Not Epub
Abstract:
Siah, the vertebrate homologue of the Drosophila seven in absentia (sina) gene, is well conserved from Drosophila to mammal and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ro H, Won M, Lee SU, Kim KE, Huh TL, Kim CH, Rhee M. Sinup, a novel Siaz-interacting nuclear protein, modulates neural plate formation in the zebrafish embryos. Biochem Biophys Res Commun. 2005 Jul 15;332(4):993-1003..

Sparc (Osteonectin) functions in morphogenesis of the pharyngeal skeleton and inner ear

Authors:
Rotllant J, Liu D, Yan YL, Postlethwait JH, Westerfield M, Du SJ
Citation:
Matrix Biol. 2008 Jul;27(6):561-72. Epub 2008 Mar 15.
Epub:
Not Epub
Abstract:
Sparc (Osteonectin), a matricellular glycoprotein expressed by many differentiated cells, is a major non-collagenous...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rotllant J, Liu D, Yan YL, Postlethwait JH, Westerfield M, Du SJ. Sparc (Osteonectin) functions in morphogenesis of the pharyngeal skeleton and inner ear. Matrix Biol. 2008 Jul;27(6):561-72. Epub 2008 Mar 15..

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