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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Down-regulation of SNAIL suppresses MIN mouse tumorigenesis: Modulation of apoptosis, proliferation, and fractal dimension

Authors:
Roy HK, Iversen P, Hart J, Liu Y, Koetsier JL, Kim Y, Kunte DP, Madugula M, Backman V, Wali RK
Citation:
Mol Cancer Ther. 2004 Sep;3(9):1159-65
Epub:
Not Epub
Abstract:
Objectives: Emerging evidence implicates the SNAIL family of transcriptional repressors in cancer development; however, the...
Delivery Method:
in vivo: injection
Organism or Cell Type:
C57BL6 APCmin mice
Citation Extract:
Roy HK, Iversen P, Hart J, Liu Y, Koetsier JL, Kim Y, Kunte DP, Madugula M, Backman V, Wali RK. Down-regulation of SNAIL suppresses MIN mouse tumorigenesis: Modulation of apoptosis, proliferation, and fractal dimension. Mol Cancer Ther. 2004 Sep;3(9):1159-65.

Embryonically Expressed GABA and Glutamate Drive Electrical Activity Regulating Neurotransmitter Specification

Authors:
Root CM, Velázquez-Ulloa NA, Monsalve GC, Minakova E, Spitzer NC
Citation:
J Neurosci. 2008 Apr 30;28(18):4777-84
Epub:
Not Epub
Abstract:
Neurotransmitter signaling in the mature nervous system is well understood, but the functions of transmitters in the immature...
Citation Extract:
Root CM, Velázquez-Ulloa NA, Monsalve GC, Minakova E, Spitzer NC. Embryonically Expressed GABA and Glutamate Drive Electrical Activity Regulating Neurotransmitter Specification. J Neurosci. 2008 Apr 30;28(18):4777-84.

Endo16 is required for gastrulation in the sea urchin Lytechinus variegatus

Authors:
Romano LA, Wray GA
Citation:
Dev Growth Differ. 2006 Oct;48(8):487-497
Epub:
Not Epub
Abstract:
The Endo16 gene encodes a large extracellular protein with several functional domains that provide some insight into the role...
Delivery Method:
Microinjection
Organism or Cell Type:
Lytechinus variegatus (sea urchin)
Citation Extract:
Romano LA, Wray GA. Endo16 is required for gastrulation in the sea urchin Lytechinus variegatus. Dev Growth Differ. 2006 Oct;48(8):487-497.

Endosomolysis by Masking of a Membrane-Active Agent (EMMA) for Cytoplasmic Release of Macromolecules

Authors:
Rozema DB, Ekena K, Lewis DL, Loomis AG, Wolff JA
Citation:
Bioconjug Chem. 2003 Jan-Feb;14(1):51
Epub:
Not Epub
Abstract:
Endosomolysis, a critical barrier to efficient delivery of macromolecules such as nucleic acids, has been breached using a...
Delivery Method:
peptide-based
Organism or Cell Type:
cell culture: HeLa AntisenseTest System
Citation Extract:
Rozema DB, Ekena K, Lewis DL, Loomis AG, Wolff JA. Endosomolysis by Masking of a Membrane-Active Agent (EMMA) for Cytoplasmic Release of Macromolecules. Bioconjug Chem. 2003 Jan-Feb;14(1):51.

EphrinB/EphB Signaling Controls Embryonic Germ Layer Separation by Contact-Induced Cell Detachment

Authors:
Rohani N, Canty L, Luu O, Fagotto F, Winklbauer R
Citation:
PLoS Biol. 2011;9(3):e1000597. doi:10.1371/journal.pbio.1000597
Epub:
Not Epub
Abstract:
Background The primordial organization of the metazoan body is achieved during gastrulation by the establishment of the germ...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Rohani N, Canty L, Luu O, Fagotto F, Winklbauer R. EphrinB/EphB Signaling Controls Embryonic Germ Layer Separation by Contact-Induced Cell Detachment. PLoS Biol. 2011;9(3):e1000597. doi:10.1371/journal.pbio.1000597.

Expression Analysis in Multiple Muscle Groups and Serum Reveals Complexity in the MicroRNA Transcriptome of the mdx Mouse with Implications for Therapy

Authors:
Roberts TC, Blomberg KEM, McClorey G, Andaloussi SEL, Godfrey C, Betts C, Coursindel T, Gait MJ, Edvard S, Wood MJA
Citation:
Mol Ther Nucleic Acids. 2012;[Epub ahead of print] doi:/10.1038/mtna.2012.26
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) are a class of small RNAs that regulate gene expression and are implicated in wide-ranging cellular...
Delivery Method:
peptide-coupled
Organism or Cell Type:
mice, mdx
Citation Extract:
Roberts TC, Blomberg KEM, McClorey G, Andaloussi SEL, Godfrey C, Betts C, Coursindel T, Gait MJ, Edvard S, Wood MJA. Expression Analysis in Multiple Muscle Groups and Serum Reveals Complexity in the MicroRNA Transcriptome of the mdx Mouse with Implications for Therapy. Mol Ther Nucleic Acids. 2012;[Epub ahead of print] doi:/10.1038/mtna.2012.26.

FGF signals guide migration of mesenchymal cells, control skeletal morphogenesis of the skeleton and regulate gastrulation during sea urchin development

Authors:
Röttinger E, Saudemont A, Duboc V, Besnardeau L, McClay D, Lepage T
Citation:
Development. 2008 Jan;135(2):353-65. Epub 2007 Dec 12
Epub:
Not Epub
Abstract:
The sea urchin embryo is emerging as an attractive model to study morphogenetic processes such as directed migration of...
Organism or Cell Type:
sea urchin
Citation Extract:
Röttinger E, Saudemont A, Duboc V, Besnardeau L, McClay D, Lepage T. FGF signals guide migration of mesenchymal cells, control skeletal morphogenesis of the skeleton and regulate gastrulation during sea urchin development. Development. 2008 Jan;135(2):353-65. Epub 2007 Dec 12.

Functional specialization of cellulose synthase genes of prokaryotic origin in chordate larvaceans

Authors:
Sagane Y, Zech K, Bouquet JM, Schmid M, Bal U, Thompson EM
Citation:
Development. 2010 May;137(9):1483-92. Epub 2010 Mar 24
Epub:
Not Epub
Abstract:
Extracellular matrices play important, but poorly investigated, roles in morphogenesis. Extracellular cellulose is central to...
Delivery Method:
Microinjection
Organism or Cell Type:
Oikopleura dioica
Citation Extract:
Sagane Y, Zech K, Bouquet JM, Schmid M, Bal U, Thompson EM. Functional specialization of cellulose synthase genes of prokaryotic origin in chordate larvaceans. Development. 2010 May;137(9):1483-92. Epub 2010 Mar 24.

Growth and differentiation of the retina and the optic tectum in the medaka fish requires olSfrp5

Authors:
Ruiz JM, Rodríguez J, Bovolenta P
Citation:
Dev Neurobiol. 2009 Jun 8. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Secreted Frizzled-Related Proteins (SFRPs) are extracellular modulators of Wnt and Bmp signaling. Previous studies in birds and...
Organism or Cell Type:
medaka
Citation Extract:
Ruiz JM, Rodríguez J, Bovolenta P. Growth and differentiation of the retina and the optic tectum in the medaka fish requires olSfrp5. Dev Neurobiol. 2009 Jun 8. [Epub ahead of print].

Heart and soul/PRKCi and nagie oko/Mpp5 regulate myocardial coherence and remodeling during cardiac morphogenesis

Authors:
Rohr S, Bit-Avragim N, Abdelilah-Seyfried S
Citation:
Development. 2006 Jan;133(1):107-15. Epub 2005 Nov 30
Epub:
Not Epub
Abstract:
Organ morphogenesis requires cellular shape changes and tissue rearrangements that occur in a precisely timed manner. Here, we...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rohr S, Bit-Avragim N, Abdelilah-Seyfried S. Heart and soul/PRKCi and nagie oko/Mpp5 regulate myocardial coherence and remodeling during cardiac morphogenesis. Development. 2006 Jan;133(1):107-15. Epub 2005 Nov 30.

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