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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Antisense oligonucleotide treatment for a pseudoexon-generating mutation in the NPC1 gene causing Niemann-Pick type C disease

Authors:
Rodríguez-Pascau L, Coll MJ, Vilageliu L, Grinberg D
Citation:
Hum Mutat. 2009 Aug 30. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Niemann-Pick type C disease is an autosomal recessive disorder caused by mutations in either the NPC1 or NPC2 gene. While most...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: human fibroblasts
Citation Extract:
Rodríguez-Pascau L, Coll MJ, Vilageliu L, Grinberg D. Antisense oligonucleotide treatment for a pseudoexon-generating mutation in the NPC1 gene causing Niemann-Pick type C disease. Hum Mutat. 2009 Aug 30. [Epub ahead of print].

Antisense PMO Found in Dystrophic Dog Model Was Effective in Cells from Exon 7-Deleted DMD Patient

Authors:
Saito T, Nakamura A, Aoki Y, Yokota T, Okada T, Osawa M, Takeda S
Citation:
PLoS ONE. 2010 Aug;5(8):e12239. doi:10.1371/journal.pone.0012239
Epub:
Not Epub
Abstract:
Background Antisense oligonucleotide-induced exon skipping is a promising approach for treatment of Duchenne muscular dystrophy...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: dog and human
Citation Extract:
Saito T, Nakamura A, Aoki Y, Yokota T, Okada T, Osawa M, Takeda S. Antisense PMO Found in Dystrophic Dog Model Was Effective in Cells from Exon 7-Deleted DMD Patient. PLoS ONE. 2010 Aug;5(8):e12239. doi:10.1371/journal.pone.0012239.

Asymmetric Involution of the Myocardial Field Drives Heart Tube Formation in Zebrafish

Authors:
Rohr S, Otten C, Abdelilah-Seyfried S
Citation:
Circ Res. 2008 Feb 1;102(2):e12-9. Epub 2008 Jan 17.
Epub:
Not Epub
Abstract:
Many vertebrate organs are derived from monolayered epithelia that undergo morphogenesis to acquire their shape. Whereas...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rohr S, Otten C, Abdelilah-Seyfried S. Asymmetric Involution of the Myocardial Field Drives Heart Tube Formation in Zebrafish. Circ Res. 2008 Feb 1;102(2):e12-9. Epub 2008 Jan 17..

BMPs and Chordin regulate patterning of the directive axis in a sea anemone

Authors:
Saina M, Genikhovich G, Renfer E, Technau U
Citation:
Proc Natl Acad Sci U S A. 2009 Oct 15. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The TGF-beta molecules Dpp/BMP2/4/7 and their antagonist Sog/Chd play a conserved role in establishing the dorso-ventral (DV)...
Organism or Cell Type:
Nematostella vectensis (cnidarian)
Citation Extract:
Saina M, Genikhovich G, Renfer E, Technau U. BMPs and Chordin regulate patterning of the directive axis in a sea anemone. Proc Natl Acad Sci U S A. 2009 Oct 15. [Epub ahead of print].

CaMK-II Activation is Essential for Zebrafish Inner Ear Development and Acts through Delta-Notch Signaling

Authors:
Rothschild SC, Lahvic J, Francescatto L, McLeod JJ, Burgess SM, Tombes RM
Citation:
Dev Biol. 2013 Jun 6. doi:pii: S0012-1606(13)00310-2. 10.1016/j.ydbio.2013.05.028. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Zebrafish inner ear development is characterized by the crystallization of otoliths onto immotile kinocilia that protrude from...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rothschild SC, Lahvic J, Francescatto L, McLeod JJ, Burgess SM, Tombes RM. CaMK-II Activation is Essential for Zebrafish Inner Ear Development and Acts through Delta-Notch Signaling. Dev Biol. 2013 Jun 6. doi:pii: S0012-1606(13)00310-2. 10.1016/j.ydbio.2013.05.028. [Epub ahead of print].

CaMK-II is a PKD2 target that promotes pronephric kidney development and stabilizes cilia

Authors:
Rothschild SC, Francescatto L, Drummond IA, Tombes RM
Citation:
Development. 2011 Jul 13. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Intracellular Ca(2+) signals influence gastrulation, neurogenesis and organogenesis through pathways that are still being...
Organism or Cell Type:
zebrafish
Citation Extract:
Rothschild SC, Francescatto L, Drummond IA, Tombes RM. CaMK-II is a PKD2 target that promotes pronephric kidney development and stabilizes cilia. Development. 2011 Jul 13. [Epub ahead of print].

Cardiac myosin light chain-2: a novel essential component of thick-myofilament assembly and contractility of the heart

Authors:
Rottbauer W, Wessels G, Dahme T, Just S, Trano N, Hassel D, Burns CG, Katus HA, Fishman MC
Citation:
Circ Res. 2006 Aug 4;99(3):323-31. Epub 2006 Jun 29
Epub:
Not Epub
Abstract:
Organism or Cell Type:
zebrafish
Citation Extract:
Rottbauer W, Wessels G, Dahme T, Just S, Trano N, Hassel D, Burns CG, Katus HA, Fishman MC. Cardiac myosin light chain-2: a novel essential component of thick-myofilament assembly and contractility of the heart. Circ Res. 2006 Aug 4;99(3):323-31. Epub 2006 Jun 29.

Caspase activation independent of cell death is required for proper cell dispersal and correct morphology in PC12 cells

Authors:
Rohn TT, Cusack SM, Kessinger SR, Oxford JT
Citation:
Exp Cell Res. 2004 Apr 15;295(1):215-25
Epub:
Not Epub
Abstract:
Caspase activation is indispensable for the proper execution of apoptosis. However, to date, little is known about other...
Delivery Method:
culture: Incubation & free uptake
Organism or Cell Type:
cell culture: PC12 cells
Citation Extract:
Rohn TT, Cusack SM, Kessinger SR, Oxford JT. Caspase activation independent of cell death is required for proper cell dispersal and correct morphology in PC12 cells. Exp Cell Res. 2004 Apr 15;295(1):215-25.

CBFbeta is a facultative Runx partner in the sea urchin embryo

Authors:
Robertson AJ, Dickey-Sims C, Ransick A, Rupp DE, McCarthy JJ, Coffman JA
Citation:
BMC Biol. 2006 Feb 9;4:4.
Epub:
Not Epub
Abstract:
ABSTRACT: BACKGROUND: Runx proteins are developmentally important metazoan transcription factors that form a heterodimeric...
Delivery Method:
Microinjection
Organism or Cell Type:
Sea urchin, Strongylocentrotus purpuratus
Citation Extract:
Robertson AJ, Dickey-Sims C, Ransick A, Rupp DE, McCarthy JJ, Coffman JA. CBFbeta is a facultative Runx partner in the sea urchin embryo. BMC Biol. 2006 Feb 9;4:4..

ccm2-like is required for cardiovascular development as a novel component of the Heg-CCM pathway

Authors:
Rosen JN, Sogah VM, Ye LY, Mably JD
Citation:
Dev Biol. 2013;[Epub ahead of print] doi:10.1016/j.ydbio.2013.01.006
Epub:
Not Epub
Abstract:
The Heart of Glass-Cerebral Cavernous Malformation (Heg-CCM) pathway is essential for normal cardiovascular development in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rosen JN, Sogah VM, Ye LY, Mably JD. ccm2-like is required for cardiovascular development as a novel component of the Heg-CCM pathway. Dev Biol. 2013;[Epub ahead of print] doi:10.1016/j.ydbio.2013.01.006.

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