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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Nodal signaling regulates endodermal cell motility and actin dynamics via Rac1 and Prex1

Authors:
Woo S, Housley MP, Weiner OD, Stainier DYR
Citation:
J Cell Biol. 2012;198(5)941-52. doi:10.1083/jcb.201203012
Epub:
Not Epub
Abstract:
Embryo morphogenesis is driven by dynamic cell behaviors, including migration, that are coordinated with fate specification and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Woo S, Housley MP, Weiner OD, Stainier DYR. Nodal signaling regulates endodermal cell motility and actin dynamics via Rac1 and Prex1. J Cell Biol. 2012;198(5)941-52. doi:10.1083/jcb.201203012.

Octa-guanidine Morpholino Restores Dystrophin Expression in Cardiac and Skeletal Muscles and Ameliorates Pathology in Dystrophic mdx Mice

Authors:
Wu B, Li Y, Morcos PA, Doran TJ, Lu P, Lu QL
Citation:
Mol Ther. 2009 May;17(5):864-71. Epub 2009 Mar 10
Epub:
Not Epub
Abstract:
Steric-block antisense oligonucleotides (AONs) are able to target RNAs for destruction and splicing alteration. Reading frame...
Delivery Method:
Vivo-Morpholino (Vivo-Porter moiety)
Organism or Cell Type:
mice, mdx
Citation Extract:
Wu B, Li Y, Morcos PA, Doran TJ, Lu P, Lu QL. Octa-guanidine Morpholino Restores Dystrophin Expression in Cardiac and Skeletal Muscles and Ameliorates Pathology in Dystrophic mdx Mice. Mol Ther. 2009 May;17(5):864-71. Epub 2009 Mar 10.

One-year Treatment of Morpholino Antisense Oligomer Improves Skeletal and Cardiac Muscle Functions in Dystrophic mdx Mice

Authors:
Wu B, Xiao B, Cloer C, Shaban M, Sali A, Lu P, Li J, Nagaraju K, Xiao X, Lu QL
Citation:
Mol Ther. 2011;19(3):576-83. doi:10.1038/mt.2010.288
Epub:
Not Epub
Abstract:
Antisense therapy has been successful to skip targeted dystrophin exon with correction of frameshift and nonsense mutations of...
Link:
http://www.sciencedirect.com/science/article/pii/S1525001616304063
Delivery Method:
Injection
Organism or Cell Type:
mice, mdx
Citation Extract:
Wu B, Xiao B, Cloer C, Shaban M, Sali A, Lu P, Li J, Nagaraju K, Xiao X, Lu QL. One-year Treatment of Morpholino Antisense Oligomer Improves Skeletal and Cardiac Muscle Functions in Dystrophic mdx Mice. Mol Ther. 2011;19(3):576-83. doi:10.1038/mt.2010.288.

Oriented cell motility and division underlie early limb bud morphogenesis

Authors:
Wyngaarden LA, Vogeli KM, Ciruna BG, Wells M, Hadjantonakis AK, Hopyan S
Citation:
Development. 2010 Aug 1;137(15):2551-8. Epub 2010 Jun 16
Epub:
Not Epub
Abstract:
The vertebrate limb bud arises from lateral plate mesoderm and its overlying ectoderm. Despite progress regarding the genetic...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wyngaarden LA, Vogeli KM, Ciruna BG, Wells M, Hadjantonakis AK, Hopyan S. Oriented cell motility and division underlie early limb bud morphogenesis. Development. 2010 Aug 1;137(15):2551-8. Epub 2010 Jun 16.

Production of Zebrafish Offspring from Cultured Female Germline Stem Cells

Authors:
Wong T-T, Tesfamichael A, Collodi P
Citation:
PLoS ONE. 2013;8(5):e62660. doi:10.1371/journal.pone.0062660
Epub:
Not Epub
Abstract:
Zebrafish female germline stem cell (FGSC) cultures were generated from a transgenic line of fish that expresses Neo and DsRed...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wong T-T, Tesfamichael A, Collodi P. Production of Zebrafish Offspring from Cultured Female Germline Stem Cells. PLoS ONE. 2013;8(5):e62660. doi:10.1371/journal.pone.0062660.

Rab13-dependent trafficking of RhoA is required for directional migration and angiogenesis

Authors:
Wu C, Agrawal S, Vasanji A, Drazba J, Sarkaria S, Xie J, Welch CM, Liu M, Anand-Apte B, Horowitz A
Citation:
J Biol Chem. 2011 Jul 1;286(26):23511-20. Epub 2011 May 4.
Epub:
Not Epub
Abstract:
Angiogenesis requires concomitant remodeling of cell junctions and migration, as exemplified by recent observations of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu C, Agrawal S, Vasanji A, Drazba J, Sarkaria S, Xie J, Welch CM, Liu M, Anand-Apte B, Horowitz A. Rab13-dependent trafficking of RhoA is required for directional migration and angiogenesis. J Biol Chem. 2011 Jul 1;286(26):23511-20. Epub 2011 May 4..

Retinotopic mapping requires focal adhesion kinase-mediated regulation of growth cone adhesion

Authors:
Woo S, Rowan DJ, Gomez TM
Citation:
J Neurosci. 2009 Nov 4;29(44):13981-91
Epub:
Not Epub
Abstract:
Adhesion controls growth cone motility, yet the effects of axon guidance cues on adhesion site dynamics are poorly understood....
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Woo S, Rowan DJ, Gomez TM. Retinotopic mapping requires focal adhesion kinase-mediated regulation of growth cone adhesion. J Neurosci. 2009 Nov 4;29(44):13981-91.

RNA-targeted splice-correction therapy for neuromuscular disease

Authors:
Wood MJ, Gait MJ, Yin H
Citation:
Brain. 2010 Feb 11. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Splice-modulation therapy, whereby molecular manipulation of premessenger RNA splicing is engineered to yield genetic...
Citation Extract:
Wood MJ, Gait MJ, Yin H. RNA-targeted splice-correction therapy for neuromuscular disease. Brain. 2010 Feb 11. [Epub ahead of print].

Role of Two Genes Encoding PACAP in Early Brain Development in Zebrafish

Authors:
Wu S, Adams BA, Fradinger EA, Sherwood NM
Citation:
Ann N Y Acad Sci. 2006 Jul;1070:602-21
Epub:
Not Epub
Abstract:
To study the role of pituitary adenylate cyclase-activating polypeptide (PACAP) in early brain development, we examined PACAP...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu S, Adams BA, Fradinger EA, Sherwood NM. Role of Two Genes Encoding PACAP in Early Brain Development in Zebrafish. Ann N Y Acad Sci. 2006 Jul;1070:602-21.

SNW1 Is a Critical Regulator of Spatial BMP Activity, Neural Plate Border Formation, and Neural Crest Specification in Vertebrate Embryos

Authors:
Wu MY, Ramel M-C, Howell M, Hill CS
Citation:
PLoS Biol. 2011;9(2):e1000593. doi:10.1371/journal.pbio.1000593
Epub:
Not Epub
Abstract:
Bone morphogenetic protein (BMP) gradients provide positional information to direct cell fate specification, such as patterning...
Delivery Method:
Microinjection
Organism or Cell Type:
Zebrafish and Xenopus laevis
Citation Extract:
Wu MY, Ramel M-C, Howell M, Hill CS. SNW1 Is a Critical Regulator of Spatial BMP Activity, Neural Plate Border Formation, and Neural Crest Specification in Vertebrate Embryos. PLoS Biol. 2011;9(2):e1000593. doi:10.1371/journal.pbio.1000593.

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