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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Advanced Morpholino Oligomers: A Novel Approach to Antiviral Therapy

Authors:
Warren TK, Shurtleff AC, Bavari S
Citation:
Antiviral Res. 2012;[Epub ahead of print] http://dx.doi.org/10.1016/j.antiviral.2012.02.004
Epub:
Not Epub
Abstract:
Phosphorodiamidate morpholino oligomers (PMOs) are synthetic antisense oligonucleotide analogs that are designed to interfere...
Citation Extract:
Warren TK, Shurtleff AC, Bavari S. Advanced Morpholino Oligomers: A Novel Approach to Antiviral Therapy. Antiviral Res. 2012;[Epub ahead of print] http://dx.doi.org/10.1016/j.antiviral.2012.02.004.

An octaguanidine-morpholino oligo conjugate improves muscle function of mdx mice

Authors:
Widrick JJ, Jiang S, Choi SJ, Knuth ST, Morcos PA
Citation:
Muscle & Nerve 2011 [Epub ahead of print]
Epub:
Not Epub
Abstract:
Introduction: Skeletal muscles of mdx mice lack functional levels of dystrophin due to a mutation in Dmd exon 23. Morpholino...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice, mdx
Citation Extract:
Widrick JJ, Jiang S, Choi SJ, Knuth ST, Morcos PA. An octaguanidine-morpholino oligo conjugate improves muscle function of mdx mice. Muscle & Nerve 2011 [Epub ahead of print].

Analysis of the zebrafish perplexed mutation reveals tissue specific roles for de novo pyrimidine synthesis during development

Authors:
Willer GB, Lee VM, Gregg RG, Link BA
Citation:
Genetics. 2005 Aug;170(4):1827-37. Epub 2005 Jun 3.
Epub:
Not Epub
Abstract:
The zebrafish perplexed mutation disrupts cell proliferation and differentiation during retinal development. In addition,...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Willer GB, Lee VM, Gregg RG, Link BA. Analysis of the zebrafish perplexed mutation reveals tissue specific roles for de novo pyrimidine synthesis during development. Genetics. 2005 Aug;170(4):1827-37. Epub 2005 Jun 3..

Angiomotin-like2 Gene (amotl2) Is Required for Migration and Proliferation of Endothelial Cells during Angiogenesis

Authors:
Wang Y, Li Z, Xu P, Huang L, Tong J, Huang H, Meng A
Citation:
J Biol Chem. 2011 Nov 25;286(47):41095-104. Epub 2011 Sep 20
Epub:
Not Epub
Abstract:
Angiogenesis involves sprouting, migration, and proliferation of endothelial cells. The angiomotin-like2 gene (amotl2) has been...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang Y, Li Z, Xu P, Huang L, Tong J, Huang H, Meng A. Angiomotin-like2 Gene (amotl2) Is Required for Migration and Proliferation of Endothelial Cells during Angiogenesis. J Biol Chem. 2011 Nov 25;286(47):41095-104. Epub 2011 Sep 20.

Antisense approaches for elucidating ranavirus gene function in an infected fish cell line

Authors:
Whitley DS, Sample RC, Sinning AR, Henegar J, Chinchar VG
Citation:
Dev Comp Immunol. 2011 Sep;35(9):937-48. doi: 10.1016/j.dci.2010.12.002. Epub 2010 Dec 13.
Epub:
Not Epub
Abstract:
Viral virulence/immune evasion strategies and host anti-viral responses represent different sides of the continuing struggle...
Link:
https://www.sciencedirect.com/science/article/pii/S0145305X10002867
Organism or Cell Type:
cell culture: fish cells, frog virus 3
Citation Extract:
Whitley DS, Sample RC, Sinning AR, Henegar J, Chinchar VG. Antisense approaches for elucidating ranavirus gene function in an infected fish cell line. Dev Comp Immunol. 2011 Sep;35(9):937-48. doi: 10.1016/j.dci.2010.12.002. Epub 2010 Dec 13..

Antisense treatments for biothreat agents

Authors:
Warfield KL, Panchal RG, Aman MJ, Bavari S
Citation:
Curr Opin Mol Ther. 2006 Apr;8(2):93-103
Epub:
Not Epub
Abstract:
Antisense oligomers (ASOs) represent a promising technology to treat viral and bacterial infections, and have already been...
Citation Extract:
Warfield KL, Panchal RG, Aman MJ, Bavari S. Antisense treatments for biothreat agents. Curr Opin Mol Ther. 2006 Apr;8(2):93-103.

Atypical E2fs Control Lymphangiogenesis through Transcriptional Regulation of Ccbe1 and Flt4

Authors:
Weijts BG, van Impel A, Schulte-Merker S, de Bruin A
Citation:
PLoS One. 2013 Sep 12;8(9):e73693. doi: 10.1371/journal.pone.0073693
Epub:
Not Epub
Abstract:
Lymphatic vessels are derived from venous endothelial cells and their formation is governed by the Vascular endothelial growth...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Weijts BG, van Impel A, Schulte-Merker S, de Bruin A. Atypical E2fs Control Lymphangiogenesis through Transcriptional Regulation of Ccbe1 and Flt4. PLoS One. 2013 Sep 12;8(9):e73693. doi: 10.1371/journal.pone.0073693.

Axial patterning interactions in the sea urchin embryo: suppression of nodal by Wnt1 signaling

Authors:
Wei Z, Range R, Angerer R, Angerer L
Citation:
Development. 2012 Mar 21. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Wnt and Nodal signaling pathways are required for initial patterning of cell fates along anterior-posterior (AP) and dorsal-...
Organism or Cell Type:
sea urchin
Citation Extract:
Wei Z, Range R, Angerer R, Angerer L. Axial patterning interactions in the sea urchin embryo: suppression of nodal by Wnt1 signaling. Development. 2012 Mar 21. [Epub ahead of print].

Basic peptide-morpholino oligomer conjugate that is very effective in killing bacteria by gene-specific and nonspecific modes

Authors:
Wesolowski D, Tae HS, Gandotra N, Llopis P, Shen N, Altman S
Citation:
PNAS. 2011;108(40):16582-7 doi:10.1073/pnas.1112561108
Epub:
Not Epub
Abstract:
Basic peptides covalently linked to nucleic acids, or chemically modified nucleic acids, enable the insertion of such a...
Link:
http://www.pnas.org/content/108/40/16582.long
Delivery Method:
peptide-coupled
Organism or Cell Type:
Bacteria, various
Citation Extract:
Wesolowski D, Tae HS, Gandotra N, Llopis P, Shen N, Altman S. Basic peptide-morpholino oligomer conjugate that is very effective in killing bacteria by gene-specific and nonspecific modes. PNAS. 2011;108(40):16582-7 doi:10.1073/pnas.1112561108.

Beta-arrestin 2 regulates zebrafish development through the hedgehog signaling pathway.

Authors:
Wilbanks AM, Fralish GB, Kirby ML, Barak LS, Li YX, Caron MG.
Citation:
Science. 2004 Dec 24;306(5705):2264-7.
Epub:
Not Epub
Abstract:
beta-arrestins are multifunctional proteins that act as scaffolds and transducers of intracellular signals from heptahelical...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wilbanks AM, Fralish GB, Kirby ML, Barak LS, Li YX, Caron MG.. Beta-arrestin 2 regulates zebrafish development through the hedgehog signaling pathway.. Science. 2004 Dec 24;306(5705):2264-7..

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