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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Cell-penetrating peptides as transporters for morpholino oligomers: effects of amino acid composition on intracellular delivery and cytotoxicity

Authors:
Wu RP, Youngblood DS, Hassinger JN, Lovejoy CE, Nelson MH, Iversen PL, Moulton HM
Citation:
Nucleic Acids Res. 2007;35(15):5182-91. Epub 2007 Aug 1
Epub:
Not Epub
Abstract:
Arginine-rich cell-penetrating peptides (CPPs) are promising transporters for intracellular delivery of antisense morpholino...
Delivery Method:
peptide-coupled
Organism or Cell Type:
cell culture: HeLa pLuc705 Antisense Test System
Citation Extract:
Wu RP, Youngblood DS, Hassinger JN, Lovejoy CE, Nelson MH, Iversen PL, Moulton HM. Cell-penetrating peptides as transporters for morpholino oligomers: effects of amino acid composition on intracellular delivery and cytotoxicity. Nucleic Acids Res. 2007;35(15):5182-91. Epub 2007 Aug 1.

Chemokine GPCR Signaling Inhibits β-Catenin during Zebrafish Axis Formation

Authors:
Wu SY, Shin J, Sepich DS, Solnica-Krezel L
Citation:
PLoS Biol. 2012;10(10):e1001403. doi:10.1371/journal.pbio.1001403
Epub:
Not Epub
Abstract:
Embryonic axis formation in vertebrates is initiated by the establishment of the dorsal Nieuwkoop blastula organizer, marked by...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu SY, Shin J, Sepich DS, Solnica-Krezel L. Chemokine GPCR Signaling Inhibits β-Catenin during Zebrafish Axis Formation. PLoS Biol. 2012;10(10):e1001403. doi:10.1371/journal.pbio.1001403.

Control of Emi2 activity and stability through Mos-mediated recruitment of PP2A

Authors:
Wu JQ, Hansen DV, Guo Y, Wang MZ, Tang W, Freel CD, Tung JJ, Jackson PK, Kornbluth S
Citation:
Proc Natl Acad Sci U S A. 2007 Oct 16;104(42):16564-9. Epub 2007 Sep 19
Epub:
Not Epub
Abstract:
Before fertilization, vertebrate eggs are arrested in meiosis II by cytostatic factor (CSF), which holds the anaphase-promoting...
Citation Extract:
Wu JQ, Hansen DV, Guo Y, Wang MZ, Tang W, Freel CD, Tung JJ, Jackson PK, Kornbluth S. Control of Emi2 activity and stability through Mos-mediated recruitment of PP2A. Proc Natl Acad Sci U S A. 2007 Oct 16;104(42):16564-9. Epub 2007 Sep 19.

Delta proteins and MAGI proteins: an interaction of Notch ligands with intracellular scaffolding molecules and its significance for zebrafish development

Authors:
Wright GJ, Leslie JD, Ariza-McNaughton L, Lewis J
Citation:
Development. 2004 Nov;131(22):5659-69
Epub:
Not Epub
Abstract:
Delta proteins activate Notch through a binding reaction that depends on their extracellular domains; but the intracellular (C-...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wright GJ, Leslie JD, Ariza-McNaughton L, Lewis J. Delta proteins and MAGI proteins: an interaction of Notch ligands with intracellular scaffolding molecules and its significance for zebrafish development. Development. 2004 Nov;131(22):5659-69.

Difference in the maternal and zygotic contributions of tumorhead on embryogenesis.

Authors:
Wu CF, Chan AP, Etkin LD
Citation:
Dev Biol 2003 Mar 15;255(2):290-302
Epub:
Not Epub
Abstract:
Tumorhead (TH) is a maternally expressed gene in Xenopus laevis, that when overexpressed, increased proliferation of ectodermal...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Wu CF, Chan AP, Etkin LD. Difference in the maternal and zygotic contributions of tumorhead on embryogenesis.. Dev Biol 2003 Mar 15;255(2):290-302.

Disrupted-in-schizophrenia 1 and neuregulin 1 are required for the specification of oligodendrocytes and neurones in the zebrafish brain

Authors:
Wood JD, Bonath F, Kumar S, Ross CA, Cunliffe VT
Citation:
Hum Mol Genet. 2008 Nov 7. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Schizophrenia may arise from subtle abnormalities in brain development due to alterations in the functions of candidate...
Organism or Cell Type:
zebrafish
Citation Extract:
Wood JD, Bonath F, Kumar S, Ross CA, Cunliffe VT. Disrupted-in-schizophrenia 1 and neuregulin 1 are required for the specification of oligodendrocytes and neurones in the zebrafish brain. Hum Mol Genet. 2008 Nov 7. [Epub ahead of print].

Dorsomorphin Promotes Survival and Germline Competence of Zebrafish Spermatogonial Stem Cells in Culture

Authors:
Wong T-T, Collodi P
Citation:
PLoS ONE. 2013;8(8):e71332. doi:10.1371/journal.pone.0071332
Epub:
Not Epub
Abstract:
Zebrafish spermatogonial cell cultures were established from Tg(piwil1:neo);Tg(piwil1:DsRed) transgenic fish using a zebrafish...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wong T-T, Collodi P. Dorsomorphin Promotes Survival and Germline Competence of Zebrafish Spermatogonial Stem Cells in Culture. PLoS ONE. 2013;8(8):e71332. doi:10.1371/journal.pone.0071332.

Dose-dependent restoration of dystrophin expression in cardiac muscle of dystrophic mice by systemically delivered morpholino

Authors:
Wu B, Lu P, Benrashid E, Malik S, Ashar J, Doran TJ, Lu QL
Citation:
Gene Ther. 2010 Jan;17(1):132-40. Epub 2009 Sep 17.
Epub:
Not Epub
Abstract:
We have earlier shown that antisense morpholino oligomers are able to restore dystrophin expression by systemic delivery in...
Delivery Method:
Injection
Organism or Cell Type:
mice, mdx
Citation Extract:
Wu B, Lu P, Benrashid E, Malik S, Ashar J, Doran TJ, Lu QL. Dose-dependent restoration of dystrophin expression in cardiac muscle of dystrophic mice by systemically delivered morpholino. Gene Ther. 2010 Jan;17(1):132-40. Epub 2009 Sep 17..

Duplicate dmbx1 genes regulate progenitor cell cycle and differentiation during zebrafish midbrain and retinal development

Authors:
Wong L, Weadick CJ, Kuo C, Chang BS, Tropepe V
Citation:
BMC Dev Biol. 2010 Sep 22;10(1):100. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: The Dmbx1 gene is important for the development of the midbrain and hindbrain, and mouse gene targeting experiments...
Organism or Cell Type:
zebrafish
Citation Extract:
Wong L, Weadick CJ, Kuo C, Chang BS, Tropepe V. Duplicate dmbx1 genes regulate progenitor cell cycle and differentiation during zebrafish midbrain and retinal development. BMC Dev Biol. 2010 Sep 22;10(1):100. [Epub ahead of print].

Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer

Authors:
Wu B, Moulton HM, Iversen PL, Jiang J, Li J, Li J, Spurney CF, Sali A, Guerron AD, Nagaraju K, Doran T, Lu P, Xiao X, Lu QL
Citation:
Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):14814-9. doi: 10.1073/pnas.0805676105. Epub 2008 Sep 19.
Epub:
Not Epub
Abstract:
Antisense oligonucleotide-mediated exon skipping is able to correct out-of-frame mutations in Duchenne muscular dystrophy and...
Delivery Method:
peptide-coupled
Organism or Cell Type:
mice, mdx
Citation Extract:
Wu B, Moulton HM, Iversen PL, Jiang J, Li J, Li J, Spurney CF, Sali A, Guerron AD, Nagaraju K, Doran T, Lu P, Xiao X, Lu QL. Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer. Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):14814-9. doi: 10.1073/pnas.0805676105. Epub 2008 Sep 19..

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