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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Arginine-rich cell penetrating peptides: Design, structure-activity, and applications to alter pre-mRNA splicing by steric-block oligonucleotides

Authors:
Abes R, Arzumanov A, Moulton H, Abes S, Ivanova G, Gait MJ, Iversen P, Lebleu B
Citation:
J Pept Sci. 2008 Jan 30; [Epub ahead of print]
Epub:
Not Epub
Abstract:
Rerouting the splicing machinery with steric-block oligonucleotides (ON) might lead to new therapeutic strategies in the...
Delivery Method:
peptide-coupled
Citation Extract:
Abes R, Arzumanov A, Moulton H, Abes S, Ivanova G, Gait MJ, Iversen P, Lebleu B. Arginine-rich cell penetrating peptides: Design, structure-activity, and applications to alter pre-mRNA splicing by steric-block oligonucleotides. J Pept Sci. 2008 Jan 30; [Epub ahead of print] .

Arteries define the position of the thyroid gland during its developmental relocalisation

Authors:
Alt B, Elsalini OA, Schrumpf P, Haufs N, Lawson ND, Schwabe GC, Mundlos S, Gruters A, Krude H, Rohr KB
Citation:
Development. 2006 Oct;133(19):3797-804
Epub:
Not Epub
Abstract:
During vertebrate development, the thyroid gland undergoes a unique relocalisation from its site of induction to a distant...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Alt B, Elsalini OA, Schrumpf P, Haufs N, Lawson ND, Schwabe GC, Mundlos S, Gruters A, Krude H, Rohr KB. Arteries define the position of the thyroid gland during its developmental relocalisation. Development. 2006 Oct;133(19):3797-804.

Beyond the Binding Site: In Vivo Identification of tbx2, smarca5 and wnt5b as Molecular Targets of CNBP during Embryonic Development

Authors:
Armas P, Margarit E, Mouguelar VS, Allende ML, Calcaterra NB
Citation:
PLoS ONE. 2013;8(5):e63234. doi:10.1371/journal.pone.0063234
Epub:
Not Epub
Abstract:
CNBP is a nucleic acid chaperone implicated in vertebrate craniofacial development, as well as in myotonic dystrophy type 2 (...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Armas P, Margarit E, Mouguelar VS, Allende ML, Calcaterra NB. Beyond the Binding Site: In Vivo Identification of tbx2, smarca5 and wnt5b as Molecular Targets of CNBP during Embryonic Development. PLoS ONE. 2013;8(5):e63234. doi:10.1371/journal.pone.0063234.

Binding of pleomorphic adenoma gene-like 2 to the tumor necrosis factor (TNF)-alpha-responsive region of the NCF2 promoter regulates p67(phox) expression and NADPH oxidase activity

Authors:
Ammons MC, Siemsen DW, Nelson-Overton LK, Quinn MT, Gauss KA
Citation:
J Biol Chem. 2007 Jun 15;282(24):17941-52. Epub 2007 Apr 26.
Epub:
Not Epub
Abstract:
NCF2, the gene encoding the NADPH oxidase cytosolic component p67(phox), is up-regulated by TNF-alpha, and we recently mapped a...
Citation Extract:
Ammons MC, Siemsen DW, Nelson-Overton LK, Quinn MT, Gauss KA. Binding of pleomorphic adenoma gene-like 2 to the tumor necrosis factor (TNF)-alpha-responsive region of the NCF2 promoter regulates p67(phox) expression and NADPH oxidase activity. J Biol Chem. 2007 Jun 15;282(24):17941-52. Epub 2007 Apr 26. .

Blocking Expression of AHR2 and ARNT1 in Zebrafish Larvae Protects Against Cardiac Toxicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin

Authors:
Antkiewicz DS, Peterson RE, Heideman W
Citation:
Toxicol Sci. 2006 Nov;94(1):175-82. Epub 2006 Aug 25.
Epub:
Not Epub
Abstract:
The zebrafish (Danio rerio) has become an attractive vertebrate model for studying developmental processes, and is emerging as...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Antkiewicz DS, Peterson RE, Heideman W. Blocking Expression of AHR2 and ARNT1 in Zebrafish Larvae Protects Against Cardiac Toxicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin. Toxicol Sci. 2006 Nov;94(1):175-82. Epub 2006 Aug 25..

Bodywide skipping of exons 45–55 in dystrophic mdx52 mice by systemic antisense delivery

Authors:
Aoki Y, Yokota T, Nagata T, Nakamura A, Tanihata J, Saito T, Duguez SMR, Nagaraju K, Hoffman EP, Partridge T, Takeda S
Citation:
PNAS. 2012;[Epub ahead of print] doi:10.1073/pnas.1204638109
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy (DMD), the commonest form of muscular dystrophy, is caused by lack of dystrophin. One of the most...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice, mdx52
Citation Extract:
Aoki Y, Yokota T, Nagata T, Nakamura A, Tanihata J, Saito T, Duguez SMR, Nagaraju K, Hoffman EP, Partridge T, Takeda S. Bodywide skipping of exons 45–55 in dystrophic mdx52 mice by systemic antisense delivery. PNAS. 2012;[Epub ahead of print] doi:10.1073/pnas.1204638109.

Cell cycle-regulated multi-site phosphorylation of Neurogenin 2 coordinates cell cycling with differentiation during neurogenesis

Authors:
Ali F, Hindley C, McDowell G, Deibler R, Jones A, Kirschner M, Guillemot F, Philpott A
Citation:
Development. 2011 Oct;138(19):4267-77. Epub 2011 Aug 18
Epub:
Not Epub
Abstract:
During development of the central nervous system, the transition from progenitor maintenance to differentiation is directly...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Ali F, Hindley C, McDowell G, Deibler R, Jones A, Kirschner M, Guillemot F, Philpott A. Cell cycle-regulated multi-site phosphorylation of Neurogenin 2 coordinates cell cycling with differentiation during neurogenesis. Development. 2011 Oct;138(19):4267-77. Epub 2011 Aug 18.

Cell-penetrating-peptide-based delivery of oligonucleotides: an overview

Authors:
Abes R, Arzumanov AA, Moulton HM, Abes S, Ivanova GD, Iversen PL, Gait MJ, Lebleu B
Citation:
Biochem Soc Trans. 2007 Aug;35(Pt 4):775-9
Epub:
Not Epub
Abstract:
Cationic CPPs (cell-penetrating peptides) have been used largely for intracellular delivery of low-molecular-mass drugs,...
Delivery Method:
peptide-coupled
Citation Extract:
Abes R, Arzumanov AA, Moulton HM, Abes S, Ivanova GD, Iversen PL, Gait MJ, Lebleu B. Cell-penetrating-peptide-based delivery of oligonucleotides: an overview. Biochem Soc Trans. 2007 Aug;35(Pt 4):775-9.

Characterization and regulation of the hb9/mnx1 beta-cell progenitor specific enhancer in zebrafish

Authors:
Arkhipova V, Wendik B, Devos N, Ek O, Peers B, Meyer D
Citation:
Dev Biol. 2012 May 1;365(1):290-302. Epub 2012 Mar 9
Epub:
Not Epub
Abstract:
Differentiation of insulin producing beta-cells is a genetically well defined process that involves functions of various...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Arkhipova V, Wendik B, Devos N, Ek O, Peers B, Meyer D. Characterization and regulation of the hb9/mnx1 beta-cell progenitor specific enhancer in zebrafish. Dev Biol. 2012 May 1;365(1):290-302. Epub 2012 Mar 9.

Combinatorial roles for BMPs and Endothelin 1 in patterning the dorsal-ventral axis of the craniofacial skeleton

Authors:
Alexander C, Zuniga E, Blitz IL, Wada N, Le Pabic P, Javidan Y, Zhang T, Cho KW, Crump JG, Schilling TF
Citation:
Development. 2011 Dec;138(23):5135-46. Epub 2011 Oct 26
Epub:
Not Epub
Abstract:
Bone morphogenetic proteins (BMPs) play crucial roles in craniofacial development but little is known about their interactions...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Alexander C, Zuniga E, Blitz IL, Wada N, Le Pabic P, Javidan Y, Zhang T, Cho KW, Crump JG, Schilling TF. Combinatorial roles for BMPs and Endothelin 1 in patterning the dorsal-ventral axis of the craniofacial skeleton. Development. 2011 Dec;138(23):5135-46. Epub 2011 Oct 26.

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