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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 11497 scientific papers returned from the database with the search filters currently being used below.

Interaction of survival of motor neuron (SMN) and HuD proteins with mRNA cpg15 rescues motor neuron axonal deficits

Authors:
Akten B, Kye MJ, Hao LT, Wertz MH, Singh S, Nie D, Huang J, Merianda TT, Twiss JL, Beattie CE, Steen JA, Sahin M
Citation:
Proc Natl Acad Sci U S A. 2011 Jun 7. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Spinal muscular atrophy (SMA), caused by the deletion of the SMN1 gene, is the leading genetic cause of infant mortality. SMN...
Organism or Cell Type:
zebrafish
Citation Extract:
Akten B, Kye MJ, Hao LT, Wertz MH, Singh S, Nie D, Huang J, Merianda TT, Twiss JL, Beattie CE, Steen JA, Sahin M. Interaction of survival of motor neuron (SMN) and HuD proteins with mRNA cpg15 rescues motor neuron axonal deficits. Proc Natl Acad Sci U S A. 2011 Jun 7. [Epub ahead of print].

Involvement of Prop1 homeobox gene in the early development of fish pituitary gland

Authors:
Angotzi AR, Mungpakdee S, Stefansson S, Male R, Chourrout D
Citation:
Gen Comp Endocrinol. 2011 Feb 26. [Epub ahead of print]
Epub:
Not Epub
Abstract:
When mutated in mammals, paired-like homeobox Prop1 gene produces highly variable pituitary phenotypes with impaired regulation...
Organism or Cell Type:
zebrafish
Citation Extract:
Angotzi AR, Mungpakdee S, Stefansson S, Male R, Chourrout D. Involvement of Prop1 homeobox gene in the early development of fish pituitary gland. Gen Comp Endocrinol. 2011 Feb 26. [Epub ahead of print].

Knockdown of a galectin-1-like protein in zebrafish (Danio rerio) causes defects in skeletal muscle development

Authors:
Ahmed H, Du SJ, Vasta GR
Citation:
Glycoconj J. 2008 Sep 2. [Epub ahead of print]
Epub:
Not Epub
Abstract:
We previously identified and characterized four galectin-1-like proteins in zebrafish, Drgal1-L1, Drgal1-L2, Drgal1-L3, and one...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ahmed H, Du SJ, Vasta GR. Knockdown of a galectin-1-like protein in zebrafish (Danio rerio) causes defects in skeletal muscle development. Glycoconj J. 2008 Sep 2. [Epub ahead of print].

Laterotopic representation of left-right information onto the dorso-ventral axis of a zebrafish midbrain target nucleus

Authors:
Aizawa H, Bianco IH, Hamaoka T, Miyashita T, Uemura O, Concha ML, Russell C, Wilson SW, Okamoto H
Citation:
Curr Biol. 2005 Feb 8;15(3):238-43
Epub:
Not Epub
Abstract:
The habenulae are part of an evolutionarily highly conserved limbic-system conduction pathway that connects telencephalic...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Aizawa H, Bianco IH, Hamaoka T, Miyashita T, Uemura O, Concha ML, Russell C, Wilson SW, Okamoto H. Laterotopic representation of left-right information onto the dorso-ventral axis of a zebrafish midbrain target nucleus. Curr Biol. 2005 Feb 8;15(3):238-43.

Lhx2 mediates the activity of Six3 in zebrafish forebrain growth

Authors:
Ando H, Kobayashi M, Tsubokawa T, Uyemura K, Furuta T, Okamoto H
Citation:
Dev Biol. 2005 Nov 15;287(2):456-68. Epub 2005 Oct 14.
Epub:
Not Epub
Abstract:
The telencephalon shows the greatest degree of size variation in the vertebrate brain. Understanding the genetic cascade that...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ando H, Kobayashi M, Tsubokawa T, Uyemura K, Furuta T, Okamoto H. Lhx2 mediates the activity of Six3 in zebrafish forebrain growth. Dev Biol. 2005 Nov 15;287(2):456-68. Epub 2005 Oct 14..

Loss and gain of FUS function impair neuromuscular synaptic transmission in a genetic model of ALS

Authors:
Armstrong GA, Drapeau P
Citation:
Hum Mol Genet. 2013 Jun 13. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Amyotrophic Lateral Sclerosis (ALS) presents clinically in adulthood and is characterized by the loss of motoneurons in the...
Organism or Cell Type:
zebrafish
Citation Extract:
Armstrong GA, Drapeau P. Loss and gain of FUS function impair neuromuscular synaptic transmission in a genetic model of ALS. Hum Mol Genet. 2013 Jun 13. [Epub ahead of print].

Loss of Dnmt1 catalytic activity reveals multiple roles for DNA methylation during pancreas development and regeneration

Authors:
Anderson RM, Bosch JA, Goll MG, Hesselson D, Dong PD, Shin D, Chi NC, Shin CH, Schlegel A, Halpern M, Stainier DY
Citation:
Dev Biol. 2009 Jul 21. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Developmental mechanisms regulating gene expression and the stable acquisition of cell fate direct cytodifferentiation during...
Organism or Cell Type:
zebrafish
Citation Extract:
Anderson RM, Bosch JA, Goll MG, Hesselson D, Dong PD, Shin D, Chi NC, Shin CH, Schlegel A, Halpern M, Stainier DY. Loss of Dnmt1 catalytic activity reveals multiple roles for DNA methylation during pancreas development and regeneration. Dev Biol. 2009 Jul 21. [Epub ahead of print].

Loss of PINK1 function affects development and results in neurodegeneration in zebrafish

Authors:
Anichtchik O, Diekmann H, Fleming A, Roach A, Goldsmith P, Rubinsztein DC
Citation:
J Neurosci. 2008 Aug 13;28(33):8199-207
Epub:
Not Epub
Abstract:
Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder in the Western world. PTEN (phosphatase/...
Organism or Cell Type:
zebrafish
Citation Extract:
Anichtchik O, Diekmann H, Fleming A, Roach A, Goldsmith P, Rubinsztein DC. Loss of PINK1 function affects development and results in neurodegeneration in zebrafish. J Neurosci. 2008 Aug 13;28(33):8199-207.

Loss of REEP4 causes paralysis of the Xenopus embryo

Authors:
Argasinska J, Rana AA, Gilchrist MJ, Lachani K, Young A, Smith JC
Citation:
Int J Dev Biol. 2009;53(1):37-43
Epub:
Not Epub
Abstract:
Members of the REEP (Receptor expression enhancing protein) family contain a TB2/DP1, HVA22 domain that is involved in...
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Argasinska J, Rana AA, Gilchrist MJ, Lachani K, Young A, Smith JC. Loss of REEP4 causes paralysis of the Xenopus embryo. Int J Dev Biol. 2009;53(1):37-43.

Loss of unc45a precipitates arteriovenous shunting in the aortic arches

Authors:
Anderson MJ, Pham VN, Vogel AM, Weinstein BM, Roman BL
Citation:
Dev Biol. 2008 Jun 15;318(2):258-67. Epub 2008 Mar 26
Epub:
Not Epub
Abstract:
Aortic arch malformations are common congenital disorders that are frequently of unknown etiology. To gain insight into the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Anderson MJ, Pham VN, Vogel AM, Weinstein BM, Roman BL. Loss of unc45a precipitates arteriovenous shunting in the aortic arches. Dev Biol. 2008 Jun 15;318(2):258-67. Epub 2008 Mar 26.

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