You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12067 scientific papers returned from the database with the search filters currently being used below.

The mitochondrial respiratory chain controls intracellular calcium signaling and NFAT activity essential for heart formation in Xenopus laevis

Authors:
Chen Y, Yuen WH, Fu J, Huang G, Melendez AJ, Ibrahim FB, Lu H, Cao X
Citation:
Mol Cell Biol. 2007 Sep;27(18):6420-32. Epub 2007 Jul 16
Epub:
Not Epub
Abstract:
The mitochondrial respiratory chain (MRC) plays crucial roles in cellular energy production. However, its function in early...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Chen Y, Yuen WH, Fu J, Huang G, Melendez AJ, Ibrahim FB, Lu H, Cao X. The mitochondrial respiratory chain controls intracellular calcium signaling and NFAT activity essential for heart formation in Xenopus laevis. Mol Cell Biol. 2007 Sep;27(18):6420-32. Epub 2007 Jul 16.

The physiological role of CTGF/CCN2 in zebrafish notochond development and biological analysis of the proximal promoter region

Authors:
Chiou MJ, Chao TT, Wu JL, Kuo CM, Chen JY
Citation:
Biochem Biophys Res Commun. 2006 Oct 20;349(2):750-8. Epub 2006 Aug 28.
Epub:
Not Epub
Abstract:
During mouse embryogenesis, CTGF/CCN2 is expressed in zones containing hypertrophic chondroctyes and calcifying cartilage such...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chiou MJ, Chao TT, Wu JL, Kuo CM, Chen JY. The physiological role of CTGF/CCN2 in zebrafish notochond development and biological analysis of the proximal promoter region. Biochem Biophys Res Commun. 2006 Oct 20;349(2):750-8. Epub 2006 Aug 28..

The toxic effect of Amiodarone on valve formation in the developing heart of zebrafish embryos

Authors:
Chen YH, Hsu RJ, Chen TY, Huang YK, Lee HC, Hu SC, Harn HJ, Jeng JR, Sun CK, Lin SZ, Tsai HJ
Citation:
Reprod Toxicol. 2011 Dec 29. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: Amiodarone is a class D drug given to treat arrhythmia, including pregnant women, but its effects on the developing...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen YH, Hsu RJ, Chen TY, Huang YK, Lee HC, Hu SC, Harn HJ, Jeng JR, Sun CK, Lin SZ, Tsai HJ. The toxic effect of Amiodarone on valve formation in the developing heart of zebrafish embryos. Reprod Toxicol. 2011 Dec 29. [Epub ahead of print].

The Transcription Factor MEF2 Directs Developmental Visually Driven Functional and Structural Metaplasticity

Authors:
Chen SX, Cherry A, Tari PK, Podgorski K, Kwong YKK, Haas K
Citation:
Cell. 2012;151(1):41–55 doi:10.1016/j.cell.2012.08.028
Epub:
Not Epub
Abstract:
Natural sensory input shapes both structure and function of developing neurons, but how early experience-driven morphological...
Delivery Method:
Vivo-Morpholino and seperately electroporation
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Chen SX, Cherry A, Tari PK, Podgorski K, Kwong YKK, Haas K. The Transcription Factor MEF2 Directs Developmental Visually Driven Functional and Structural Metaplasticity. Cell. 2012;151(1):41–55 doi:10.1016/j.cell.2012.08.028.

The voltage-gated calcium channel CACNB2 (β2.1) protein is required in the heart for control of cell proliferation and heart tube integrity

Authors:
Chernyavskaya Y, Ebert AM, Milligan E, Garrity DM
Citation:
Dev Dyn. 2012 Jan 23. doi: 10.1002/dvdy.23746. [Epub ahead of print]
Epub:
Not Epub
Abstract:
L-type calcium channels (LTCC) regulate calcium entry into cardiomyocytes. CACNB2 (β2) LTCC auxiliary subunits traffic the pore...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chernyavskaya Y, Ebert AM, Milligan E, Garrity DM. The voltage-gated calcium channel CACNB2 (β2.1) protein is required in the heart for control of cell proliferation and heart tube integrity. Dev Dyn. 2012 Jan 23. doi: 10.1002/dvdy.23746. [Epub ahead of print].

Transcription cofactor Vgl-2 is required for skeletal muscle differentiation

Authors:
Chen HH, Maeda T, Mullett SJ, Stewart AF
Citation:
Genesis. 2004 Aug;39(4):273-9
Epub:
Not Epub
Abstract:
TEF-1 transcription factors regulate gene expression in skeletal muscle but are not muscle-specific. Instead, TEF-1 factors...
Organism or Cell Type:
cell culture: myogenic C(2)C(12) cells and chick embryos
Citation Extract:
Chen HH, Maeda T, Mullett SJ, Stewart AF. Transcription cofactor Vgl-2 is required for skeletal muscle differentiation. Genesis. 2004 Aug;39(4):273-9.

Treatment with Myf5-morpholino results in somite patterning and brain formation defects in zebrafish

Authors:
Chen YH, Tsai HJ
Citation:
Differentiation. 2002 Oct;70(8):447-56
Epub:
Not Epub
Abstract:
Myf-5 is a stage-dependent transcription factor associated with somitogenesis. To study its biological functions in zebrafish,...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen YH, Tsai HJ. Treatment with Myf5-morpholino results in somite patterning and brain formation defects in zebrafish. Differentiation. 2002 Oct;70(8):447-56.

Use of zebrafish and knockdown technology to define proprotein convertase activity

Authors:
Chitramuthu BP, Bennett HP
Citation:
Methods Mol Biol. 2011;768:273-96
Epub:
Not Epub
Abstract:
The Zebrafish (Danio rerio) is a powerful and well-established tool used extensively for the study of early vertebrate...
Organism or Cell Type:
zebrafish
Citation Extract:
Chitramuthu BP, Bennett HP. Use of zebrafish and knockdown technology to define proprotein convertase activity. Methods Mol Biol. 2011;768:273-96.

Vascular Endothelial Growth Factor Receptor 1 (VEGFR1) Morpholino Increases Graft Survival in a Murine Penetrating Keratoplasty Model

Authors:
Cho YK, Zhang X, Uehara H, Young JR, Archer B, Ambati B
Citation:
Invest Ophthalmol Vis Sci. 2012;[Epub ahead of print] doi:10.1167/iovs.12-10408
Epub:
Not Epub
Abstract:
Purpose: This study sought to determine whether a Vascular Endothelial Growth Factor Receptor 1 (VEGFR1)-specific morpholino...
Delivery Method:
Injection, subconjunctival
Organism or Cell Type:
mice
Citation Extract:
Cho YK, Zhang X, Uehara H, Young JR, Archer B, Ambati B. Vascular Endothelial Growth Factor Receptor 1 (VEGFR1) Morpholino Increases Graft Survival in a Murine Penetrating Keratoplasty Model. Invest Ophthalmol Vis Sci. 2012;[Epub ahead of print] doi:10.1167/iovs.12-10408 .

Vascular Endothelial Growth Factor Receptor 1 morpholino decreases angiogenesis in a murine corneal suture model

Authors:
Cho YK, Uehara H, Young JR, Archer B, Zhang X, Ambati B
Citation:
IOVS. 2011;[epub ahead of print] doi:10.1167/iovs.11-8391
Epub:
Not Epub
Abstract:
Purpose: This study sought to determine whether a VEGFR1-specific morpholino could induce the alternative splicing of Flt-1 pre...
Delivery Method:
Injection, corneal
Organism or Cell Type:
mice
Citation Extract:
Cho YK, Uehara H, Young JR, Archer B, Zhang X, Ambati B. Vascular Endothelial Growth Factor Receptor 1 morpholino decreases angiogenesis in a murine corneal suture model. IOVS. 2011;[epub ahead of print] doi:10.1167/iovs.11-8391.

Pages