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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

PEAR1 attenuates megakaryopoiesis via control of the PI3K/PTEN pathway

Authors:
Kauskot A, Vandenbriele C, Louwette S, Gijsbers R, Tousseyn T, Freson K, Verhamme P, Hoylaerts MF
Citation:
Blood. 2013 Jun 27;121(26):5208-17. doi: 10.1182/blood-2012-10-462887. Epub 2013 May 10.
Epub:
Not Epub
Abstract:
Platelet Endothelial Aggregation Receptor-1 (PEAR1) participates in platelet aggregation via sustaining αIIbβ3 activation. To...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kauskot A, Vandenbriele C, Louwette S, Gijsbers R, Tousseyn T, Freson K, Verhamme P, Hoylaerts MF. PEAR1 attenuates megakaryopoiesis via control of the PI3K/PTEN pathway. Blood. 2013 Jun 27;121(26):5208-17. doi: 10.1182/blood-2012-10-462887. Epub 2013 May 10..

Plasmonic laser treatment for Morpholino oligomer delivery in antisense applications

Authors:
Kalies S, Heinemann D, Schomaker M, Escobar HM, Heisterkamp A, Ripken T, Meyer H
Citation:
J Biophoton. 2014;7: 825–33. doi: 10.1002/jbio.201300056
Epub:
Not Epub
Abstract:
Several cell transfection techniques have been developed in the last decades for specific applications and for various types of...
Delivery Method:
gold nanoparticle mediated laser transfection
Organism or Cell Type:
cell culture: ZMTH3 cells
Citation Extract:
Kalies S, Heinemann D, Schomaker M, Escobar HM, Heisterkamp A, Ripken T, Meyer H. Plasmonic laser treatment for Morpholino oligomer delivery in antisense applications. J Biophoton. 2014;7: 825–33. doi: 10.1002/jbio.201300056.

Polycomb group gene mel-18 modulates the self-renewal activity and cell cycle status of hematopoietic stem cells

Authors:
Kajiume T, Ninomiya Y, Ishihara H, Kanno R, Kanno M
Citation:
Exp Hematol. 2004 Jun;32(6):571-8
Epub:
Not Epub
Abstract:
OBJECTIVE: Mel-18 is a member of the mammalian Polycomb group (PcG) genes. This family of genes regulates global gene...
Delivery Method:
Special Delivery
Organism or Cell Type:
in vitro: mel-18 transgenic GFP tg mice- colony-forming cell
Citation Extract:
Kajiume T, Ninomiya Y, Ishihara H, Kanno R, Kanno M. Polycomb group gene mel-18 modulates the self-renewal activity and cell cycle status of hematopoietic stem cells. Exp Hematol. 2004 Jun;32(6):571-8.

Promising nucleic acid analogs and mimics: characteristic features and applications of PNA, LNA, and morpholino

Authors:
Karkare S, Bhatnagar D
Citation:
Appl Microbiol Biotechnol. 2006 Aug;71(5):575-86. Epub 2006 May 9
Epub:
Not Epub
Abstract:
Nucleic acid analogs and mimics are commonly the modifications of native nucleic acids at the nucleobase, the sugar ring, or...
Delivery Method:
Not Specific
Organism or Cell Type:
not applicable
Citation Extract:
Karkare S, Bhatnagar D. Promising nucleic acid analogs and mimics: characteristic features and applications of PNA, LNA, and morpholino. Appl Microbiol Biotechnol. 2006 Aug;71(5):575-86. Epub 2006 May 9.

Protein kinase D2 controls cardiac valve formation in zebrafish by regulating histone deacetylase 5 activity

Authors:
Just S, Berger IM, Meder B, Backs J, Keller A, Marquart S, Frese K, Patzel E, Rauch GJ; Tübingen 2000 Screen Consortium, Katus HA, Rottbauer W
Citation:
Circulation. 2011 Jul 19;124(3):324-34. Epub 2011 Jul 5
Epub:
Not Epub
Abstract:
BACKGROUND: The molecular mechanisms that guide heart valve formation are not well understood. However, elucidation of the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Just S, Berger IM, Meder B, Backs J, Keller A, Marquart S, Frese K, Patzel E, Rauch GJ; Tübingen 2000 Screen Consortium, Katus HA, Rottbauer W. Protein kinase D2 controls cardiac valve formation in zebrafish by regulating histone deacetylase 5 activity. Circulation. 2011 Jul 19;124(3):324-34. Epub 2011 Jul 5.

Quantitative assessment of the knockdown efficiency of morpholino antisense oligonucleotides in zebrafish embryos using a luciferase assay

Authors:
Kamachi Y, Okuda Y, Kondoh H
Citation:
Genesis. 2008 Jan 14;46(1):1-7 [Epub ahead of print]
Epub:
Not Epub
Abstract:
Despite the broad use of morpholino antisense oligonucleotides (MO) to knockdown gene function in zebrafish embryos, the...
Organism or Cell Type:
zebrafish
Citation Extract:
Kamachi Y, Okuda Y, Kondoh H. Quantitative assessment of the knockdown efficiency of morpholino antisense oligonucleotides in zebrafish embryos using a luciferase assay. Genesis. 2008 Jan 14;46(1):1-7 [Epub ahead of print].

R-Spondin2 Is a Secreted Activator of Wnt/beta-Catenin Signaling and Is Required for Xenopus Myogenesis

Authors:
Kazanskaya O, Glinka A, Del Barco Barrantes I, Stannek P, Niehrs C, Wu W
Citation:
Dev Cell. 2004 Oct;7(4):525-34
Epub:
Not Epub
Abstract:
We have carried out a small pool expression screen for modulators of the Wnt/beta-catenin pathway and identified Xenopus R-...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Kazanskaya O, Glinka A, Del Barco Barrantes I, Stannek P, Niehrs C, Wu W. R-Spondin2 Is a Secreted Activator of Wnt/beta-Catenin Signaling and Is Required for Xenopus Myogenesis. Dev Cell. 2004 Oct;7(4):525-34.

Regulation of NF-kappaB/Rel by IkappaB is essential for ascidian notochord formation

Authors:
Kawai N, Takahashi H, Nishida H, Yokosawa H
Citation:
Dev Biol. 2005 Jan 1;277(1):80-91
Epub:
Not Epub
Abstract:
We previously reported that two NF-kappaB/Rel family members are involved in notochord formation of the ascidian Halocynthia...
Delivery Method:
Microinjection
Organism or Cell Type:
Ciona intestinalis
Citation Extract:
Kawai N, Takahashi H, Nishida H, Yokosawa H. Regulation of NF-kappaB/Rel by IkappaB is essential for ascidian notochord formation. Dev Biol. 2005 Jan 1;277(1):80-91.

Requirement for frzb and fzd7a in cranial neural crest convergence and extension mechanisms during zebrafish palate and jaw morphogenesis

Authors:
Kamel G, Hoyos T, Rochard L, Dougherty M, Tse W, Shubinets V, Grimaldi M, Liao EC
Citation:
Dev Biol. 2013 Jun 24. doi:pii: S0012-1606(13)00329-1. 10.1016/j.ydbio.2013.06.012. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Regulation of convergence and extension by wnt-frizzled signaling is a common theme in embryogenesis. This study examines the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kamel G, Hoyos T, Rochard L, Dougherty M, Tse W, Shubinets V, Grimaldi M, Liao EC. Requirement for frzb and fzd7a in cranial neural crest convergence and extension mechanisms during zebrafish palate and jaw morphogenesis. Dev Biol. 2013 Jun 24. doi:pii: S0012-1606(13)00329-1. 10.1016/j.ydbio.2013.06.012. [Epub ahead of print].

Rer1p maintains ciliary length and signaling by regulating γ-secretase activity and Foxj1a levels

Authors:
Jurisch-Yaksi N, Rose AJ, Lu H, Raemaekers T, Munck S, Baatsen P, Baert V, Vermeire W, Scales SJ, Verleyen D, Vandepoel R, Tylzanowski P, Yaksi E, de Ravel T, Yost HJ, Froyen G, Arrington CB, Annaert W
Citation:
J Cell Biol. 2013 Mar 18;200(6):709-20. doi: 10.1083/jcb.201208175. Epub 2013 Mar 11.
Epub:
Not Epub
Abstract:
Cilia project from the surface of most vertebrate cells and are important for several physiological and developmental processes...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jurisch-Yaksi N, Rose AJ, Lu H, Raemaekers T, Munck S, Baatsen P, Baert V, Vermeire W, Scales SJ, Verleyen D, Vandepoel R, Tylzanowski P, Yaksi E, de Ravel T, Yost HJ, Froyen G, Arrington CB, Annaert W. Rer1p maintains ciliary length and signaling by regulating γ-secretase activity and Foxj1a levels. J Cell Biol. 2013 Mar 18;200(6):709-20. doi: 10.1083/jcb.201208175. Epub 2013 Mar 11..

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