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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo

Authors:
Kabashi E, Lin L, Tradewell ML, Dion PA, Bercier V, Bourgouin P, Rochefort D, Bel Hadj S, Durham HD, Vande Velde C, Rouleau GA, Drapeau P
Citation:
Hum Mol Genet. 2010 Feb 15;19(4):671-83. Epub 2009 Dec 3. Erratum in: Hum Mol Genet. 2010 Aug 1;19(15):3102
Epub:
Not Epub
Abstract:
TDP-43 has been found in inclusion bodies of multiple neurological disorders, including amyotrophic lateral sclerosis,...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kabashi E, Lin L, Tradewell ML, Dion PA, Bercier V, Bourgouin P, Rochefort D, Bel Hadj S, Durham HD, Vande Velde C, Rouleau GA, Drapeau P. Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo. Hum Mol Genet. 2010 Feb 15;19(4):671-83. Epub 2009 Dec 3. Erratum in: Hum Mol Genet. 2010 Aug 1;19(15):3102.

Gelsolin is a dorsalizing factor in zebrafish

Authors:
Kanungo J, Kozmik Z, Swamynathan SK, Piatigorsky J
Citation:
Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3287-92
Epub:
Not Epub
Abstract:
The gene for gelsolin (an actin-binding, cytoskeletal regulatory protein) was shown earlier to be specialized for high corneal...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kanungo J, Kozmik Z, Swamynathan SK, Piatigorsky J. Gelsolin is a dorsalizing factor in zebrafish. Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3287-92.

Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development

Authors:
Karlstrom RO, Tyurina OV, Kawakami A, Nishioka N, Talbot WS, Sasaki H, Schier AF
Citation:
Development 2003 Apr 15;130(8):1549-1564
Epub:
Not Epub
Abstract:
Gli proteins regulate the transcription of Hedgehog (Hh) target genes. Genetic studies in mouse have shown that Gli1 is not...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Karlstrom RO, Tyurina OV, Kawakami A, Nishioka N, Talbot WS, Sasaki H, Schier AF. Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development. Development 2003 Apr 15;130(8):1549-1564.

Genetic dissection of dopaminergic and noradrenergic contributions to catecholaminergic tracts in early larval zebrafish

Authors:
Kastenhuber E, Kratochwil CF, Ryu S, Schweitzer J, Driever W
Citation:
J Comp Neurol. 2010 Feb 15;518(4):439-58
Epub:
Not Epub
Abstract:
The catecholamines dopamine and noradrenaline provide some of the major neuromodulatory systems with far-ranging projections in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kastenhuber E, Kratochwil CF, Ryu S, Schweitzer J, Driever W. Genetic dissection of dopaminergic and noradrenergic contributions to catecholaminergic tracts in early larval zebrafish. J Comp Neurol. 2010 Feb 15;518(4):439-58.

Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP-1

Authors:
Kassel O, Sancono A, Kratzschmar J, Kreft B, Stassen M, Cato AC
Citation:
EMBO J. 2001 Dec 17;20(24):7108-16
Epub:
Not Epub
Abstract:
Glucocorticoids inhibit the proinflammatory activities of transcription factors such as AP-1 and NF-kappa B as well as that of...
Delivery Method:
Scrape Delivery
Organism or Cell Type:
cell culture: mast cells
Citation Extract:
Kassel O, Sancono A, Kratzschmar J, Kreft B, Stassen M, Cato AC. Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP-1. EMBO J. 2001 Dec 17;20(24):7108-16.

Heparan sulfate modification of the transmembrane receptor CD47 is necessary for inhibition of T cell receptor signaling by thrombospondin-1

Authors:
Kaur S, Kuznetsova SA, Pendrak ML, Sipes JM, Romeo MJ, Li Z, Zhang L, Roberts DD
Citation:
J Biol Chem. 2011 Apr 29;286(17):14991-5002. Epub 2011 Feb 22
Epub:
Not Epub
Abstract:
Cell surface proteoglycans on T cells contribute to retroviral infection, binding of chemokines and other proteins, and are...
Delivery Method:
Electroporation (Amaxa)
Organism or Cell Type:
cell culture: Jurkat T cell
Citation Extract:
Kaur S, Kuznetsova SA, Pendrak ML, Sipes JM, Romeo MJ, Li Z, Zhang L, Roberts DD. Heparan sulfate modification of the transmembrane receptor CD47 is necessary for inhibition of T cell receptor signaling by thrombospondin-1. J Biol Chem. 2011 Apr 29;286(17):14991-5002. Epub 2011 Feb 22.

Histone Deacetylase 9 Promotes Angiogenesis by Targeting the Antiangiogenic MicroRNA 17-92 Cluster in Endothelial Cells

Authors:
Kaluza D, Kroll J, Gesierich S, Manavski Y, Boeckel JN, Doebele C, Zelent A, Rössig L, Zeiher AM, Augustin HG, Urbich C, Dimmeler S
Citation:
Arterioscler Thromb Vasc Biol. 2013 Mar;33(3):533-43. doi: 10.1161/ATVBAHA.112.300415. Epub 2013 Jan 3.
Epub:
Not Epub
Abstract:
OBJECTIVE: Histone deacetylases (HDACs) modulate gene expression by deacetylation of histone and nonhistone proteins. Several...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kaluza D, Kroll J, Gesierich S, Manavski Y, Boeckel JN, Doebele C, Zelent A, Rössig L, Zeiher AM, Augustin HG, Urbich C, Dimmeler S. Histone Deacetylase 9 Promotes Angiogenesis by Targeting the Antiangiogenic MicroRNA 17-92 Cluster in Endothelial Cells. Arterioscler Thromb Vasc Biol. 2013 Mar;33(3):533-43. doi: 10.1161/ATVBAHA.112.300415. Epub 2013 Jan 3..

Identification of a retinoic acid-responsive neural enhancer in the Ciona intestinalis Hox1 gene

Authors:
Kanda M, Ikeda T, Fujiwara S
Citation:
Dev Growth Differ. 2013 Feb;55(2):260-9. doi: 10.1111/dgd.12033. Epub 2013 Jan 10.
Epub:
Not Epub
Abstract:
The Hox1 gene in the urochordate ascidian Ciona intestinalis (Ci-Hox1) is expressed in the nerve cord and epidermis. We...
Delivery Method:
Microinjection
Organism or Cell Type:
Ciona intestinalis
Citation Extract:
Kanda M, Ikeda T, Fujiwara S. Identification of a retinoic acid-responsive neural enhancer in the Ciona intestinalis Hox1 gene. Dev Growth Differ. 2013 Feb;55(2):260-9. doi: 10.1111/dgd.12033. Epub 2013 Jan 10..

Impairment of the tRNA splicing endonuclease subunit 54 (tsen54) gene causes neurological abnormalities and larval death in zebrafish models of Pontocerebellar Hypoplasia

Authors:
Kasher PR, Namavar Y, van Tijn P, Fluiter K, Sizarov A, Kamermans M, Grierson AJ, Zivkovic D, Baas F
Citation:
Hum Mol Genet. 2011 Apr 15;20(8):1574-84. doi: 10.1093/hmg/ddr034. Epub 2011 Jan 27.
Epub:
Not Epub
Abstract:
Pontocerebellar hypoplasia (PCH) represents a group (PCH1-6) of neurodegenerative autosomal recessive disorders characterised...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kasher PR, Namavar Y, van Tijn P, Fluiter K, Sizarov A, Kamermans M, Grierson AJ, Zivkovic D, Baas F. Impairment of the tRNA splicing endonuclease subunit 54 (tsen54) gene causes neurological abnormalities and larval death in zebrafish models of Pontocerebellar Hypoplasia. Hum Mol Genet. 2011 Apr 15;20(8):1574-84. doi: 10.1093/hmg/ddr034. Epub 2011 Jan 27..

Insulin-like growth factor-binding protein-1 (IGFBP-1) mediates hypoxia-induced embryonic growth and developmental retardation

Authors:
Kajimura S, Aida K, Duan C
Citation:
Proc Natl Acad Sci U S A. 2005 Jan 25;102(4):1240-5. Epub 2005 Jan 11
Epub:
Not Epub
Abstract:
Although reduced fetal growth in response to hypoxia has been appreciated for decades, we have a poor understanding of the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kajimura S, Aida K, Duan C. Insulin-like growth factor-binding protein-1 (IGFBP-1) mediates hypoxia-induced embryonic growth and developmental retardation. Proc Natl Acad Sci U S A. 2005 Jan 25;102(4):1240-5. Epub 2005 Jan 11.

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