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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Inhibition of Plk1 Induces Mitotic Infidelity and Embryonic Growth Defects in Developing Zebrafish Embryos

Authors:
Jeong KH, Jeong JY, Lee HO, Choi E, Lee H
Citation:
Dev Biol. 2010 Jun 5. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Polo-like kinase 1 (Plk1) is central to cell division. Here, we report that Plk1 is critical for mitosis in the embryonic...
Organism or Cell Type:
zebrafish
Citation Extract:
Jeong KH, Jeong JY, Lee HO, Choi E, Lee H. Inhibition of Plk1 Induces Mitotic Infidelity and Embryonic Growth Defects in Developing Zebrafish Embryos. Dev Biol. 2010 Jun 5. [Epub ahead of print].

Integrinalpha5 and Delta/Notch Signaling Have Complementary Spatiotemporal Requirements during Zebrafish Somitogenesis

Authors:
Jülich D, Geisler R, Holley SA; Tu bingen 2000 Screen Consortium
Citation:
Dev Cell. 2005 Apr;8(4):575-586
Epub:
Not Epub
Abstract:
Somitogenesis is the process by which the segmented precursors of the skeletal muscle and vertebral column are generated during...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jülich D, Geisler R, Holley SA; Tu bingen 2000 Screen Consortium. Integrinalpha5 and Delta/Notch Signaling Have Complementary Spatiotemporal Requirements during Zebrafish Somitogenesis. Dev Cell. 2005 Apr;8(4):575-586.

Kinase activity-independent regulation of cyclin pathway by GRK2 is essential for zebrafish early development

Authors:
Jiang X, Yang P, Ma L
Citation:
Proc Natl Acad Sci U S A. 2009 Jun 5. [Epub ahead of print]
Epub:
Not Epub
Abstract:
G protein-coupled receptor (GPCR) kinases (GRKs) are known as a family of serine/threonine kinases that function as key...
Organism or Cell Type:
zebrafish
Citation Extract:
Jiang X, Yang P, Ma L. Kinase activity-independent regulation of cyclin pathway by GRK2 is essential for zebrafish early development. Proc Natl Acad Sci U S A. 2009 Jun 5. [Epub ahead of print].

Long-Term Improvement in mdx Cardiomyopathy after Therapy with Peptide-conjugated Morpholino Oligomers

Authors:
Jearawiriyapaisarn N, Moulton HM, Sazani P, Kole R, Willis MS
Citation:
Cardiovasc Res. 2010 Feb 1;85(3):444-53. doi: 10.1093/cvr/cvp335. Epub 2009 Oct 8.
Epub:
Not Epub
Abstract:
AIMS: The cardiomyopathy found in Duchenne muscular dystrophy (DMD) is responsible for death due to heart failure in...
Delivery Method:
peptide-coupled
Organism or Cell Type:
mice, mdx
Citation Extract:
Jearawiriyapaisarn N, Moulton HM, Sazani P, Kole R, Willis MS. Long-Term Improvement in mdx Cardiomyopathy after Therapy with Peptide-conjugated Morpholino Oligomers. Cardiovasc Res. 2010 Feb 1;85(3):444-53. doi: 10.1093/cvr/cvp335. Epub 2009 Oct 8..

Maternally and zygotically provided Cdx2 have novel and critical roles for early development of the mouse embryo

Authors:
Jedrusik A, Bruce AW, Tan MH, Leong DE, Skamagki M, Yao M, Zernicka-Goetz M
Citation:
Dev Biol. 2010 Aug 1;344(1):66-78. doi: 10.1016/j.ydbio.2010.04.017. Epub 2010 Apr 27.
Epub:
Not Epub
Abstract:
Divisions of polarised blastomeres that allocate polar cells to outer and apolar cells to inner positions initiate the first...
Organism or Cell Type:
Mouse embryo
Citation Extract:
Jedrusik A, Bruce AW, Tan MH, Leong DE, Skamagki M, Yao M, Zernicka-Goetz M. Maternally and zygotically provided Cdx2 have novel and critical roles for early development of the mouse embryo. Dev Biol. 2010 Aug 1;344(1):66-78. doi: 10.1016/j.ydbio.2010.04.017. Epub 2010 Apr 27..

Matrix metalloproteinase 14 in the zebrafish: an eye on retinal and retinotectal development

Authors:
Janssens E, Gaublomme D, De Groef L, Darras VM, Arckens L, Delorme N, Claes F, Van Hove I, Moons L
Citation:
PLoS One. 2013;8(1):e52915. doi: 10.1371/journal.pone.0052915. Epub 2013 Jan 9
Epub:
Not Epub
Abstract:
BACKGROUND: Matrix metalloproteinases (MMPs) are members of the metzincin superfamily of proteinases that cleave structural...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Janssens E, Gaublomme D, De Groef L, Darras VM, Arckens L, Delorme N, Claes F, Van Hove I, Moons L. Matrix metalloproteinase 14 in the zebrafish: an eye on retinal and retinotectal development. PLoS One. 2013;8(1):e52915. doi: 10.1371/journal.pone.0052915. Epub 2013 Jan 9.

miR-30a Regulates Endothelial Tip Cell Formation and Arteriolar Branching

Authors:
Jiang Q, Lagos-Quintana M, Liu D, Shi Y, Helker C, Herzog W, le Noble F
Citation:
Hypertension. 2013 Jul 1. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Microvascular rarefaction increases vascular resistance and pressure in systemic arteries and is a hallmark of fixed essential...
Organism or Cell Type:
zebrafish
Citation Extract:
Jiang Q, Lagos-Quintana M, Liu D, Shi Y, Helker C, Herzog W, le Noble F. miR-30a Regulates Endothelial Tip Cell Formation and Arteriolar Branching. Hypertension. 2013 Jul 1. [Epub ahead of print].

mRNA for N-Bak, a neuron-specific BH3-only splice isoform of Bak, escapes nonsense-mediated decay and is translationally repressed in the neurons

Authors:
Jakobson M, Lintulahti A, Arumäe U
Citation:
Cell Death Dis. 2012 Feb 2;3:e269. doi: 10.1038/cddis.2012.4
Epub:
Not Epub
Abstract:
mRNA for neuronal Bak (N-Bak), a splice variant of pro-apoptotic Bcl-2 family member Bak is expressed in the neurons....
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: mouse neurons
Citation Extract:
Jakobson M, Lintulahti A, Arumäe U. mRNA for N-Bak, a neuron-specific BH3-only splice isoform of Bak, escapes nonsense-mediated decay and is translationally repressed in the neurons. Cell Death Dis. 2012 Feb 2;3:e269. doi: 10.1038/cddis.2012.4.

Nanos functions to maintain the fate of the small micromere lineage in the sea urchin embryo

Authors:
Juliano CE, Yajima M, Wessel GM
Citation:
Dev Biol. 2010 Jan 15;337(2):220-32. Epub 2009 Oct 28
Epub:
Not Epub
Abstract:
The translational regulator nanos is required for the survival and maintenance of primordial germ cells during embryogenesis....
Delivery Method:
Microinjection
Organism or Cell Type:
Sea urchin, Strongylocentrotus purpuratus
Citation Extract:
Juliano CE, Yajima M, Wessel GM. Nanos functions to maintain the fate of the small micromere lineage in the sea urchin embryo. Dev Biol. 2010 Jan 15;337(2):220-32. Epub 2009 Oct 28.

NANOS3 function in human germ cell development

Authors:
Julaton VT, Pera RA
Citation:
Hum Mol Genet. 2011 Mar 19. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Human infertility is common and frequently linked to poor germ cell development. Yet, human germ cell development is poorly...
Delivery Method:
Electroporation (Amaxa)
Organism or Cell Type:
Cell culture: human embryonic stem cells (hESC) H9 (XX)
Citation Extract:
Julaton VT, Pera RA. NANOS3 function in human germ cell development. Hum Mol Genet. 2011 Mar 19. [Epub ahead of print].

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