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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
A nonsense variant in NME5 causes human primary ciliary dyskinesia with radial spoke defects
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Citation:
Clin Genet. 2020 Mar 17. doi: 10.1111/cge.13742. [Epub ahead of print] Epub:
Yes Abstract:
Primary ciliary dyskinesia (PCD) is a genetically heterogeneous disorder characterized by defects in the function or structure... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cho EH, Huh HJ, Jeong I, Lee NY, Koh WJ, Park HC, Ki CS. A nonsense variant in NME5 causes human primary ciliary dyskinesia with radial spoke defects. Clin Genet. 2020 Mar 17. doi: 10.1111/cge.13742. [Epub ahead of print]. |
The vitamin B12 processing enzyme, mmachc, is essential for zebrafish survival, growth and retinal morphology
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Citation:
Hum Molec Genet. 2020;[Epub anead of print] doi:10.1093/hmg/ddaa044 Epub:
Yes Abstract:
Cobalamin C deficiency (cblC), the most common inborn error of intracellular cobalamin metabolism, is caused by mutations in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sloan JL, Achilly NP, Arnold ML, Catlett JL, Blake T, Bishop K, Jones M, Harper U, English MA, Anderson S, Trivedi NS, Elkahloun A, Hoffmann V, Brooks BP, Sood R, Venditti CP. The vitamin B12 processing enzyme, mmachc, is essential for zebrafish survival, growth and retinal morphology. Hum Molec Genet. 2020;[Epub anead of print] doi:10.1093/hmg/ddaa044. |
Gsx2 is involved in specification of neurons in the inferior olivary nuclei from Ptf1a-expressing neuronal progenitors in zebrafish
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.03.16.993402 Epub:
Not Epub Abstract:
Neurons in the inferior olivary nuclei (IO neurons) send climbing fibers to Purkinje cells to elicit functions of the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Itoh T, Miki T, Sakagami M, Asakawa K, Kawakami K, Shimizu T, Hibi M. Gsx2 is involved in specification of neurons in the inferior olivary nuclei from Ptf1a-expressing neuronal progenitors in zebrafish. bioRxiv. 2020;[preprint] doi:10.1101/2020.03.16.993402 . |
Role of the ADCY9 gene in cardiac abnormalities of the Rubinstein-Taybi syndrome
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Citation:
Research Square. 2020;[preprint] doi:10.21203/rs.2.19377/v2 Epub:
Not Epub Abstract:
Background ： Rubinstein–Taybi syndrome (RSTS) is a rare, congenital, plurimalformative, and neurodevelopmental disorder.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wu Y, Xia Y, Li P, Qu H-Q, Liu Y, Yang Y, Lin J, Zheng M, Tian L, Wu Z, Huang S, Qin X, Zhou X, Chen S, Liu Y, Wang Y, Li X, Zeng H, Hakonarson H, Zhuang J. Role of the ADCY9 gene in cardiac abnormalities of the Rubinstein-Taybi syndrome. Research Square. 2020;[preprint] doi:10.21203/rs.2.19377/v2. |
The autophagic response to Staphylococcus aureus provides an intracellular niche in neutrophils
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Citation:
Autophagy. 2020;[Epub] doi:10.1080/15548627.2020.1739443 Epub:
Yes Abstract:
Staphylococcus aureus is a major human pathogen causing multiple pathologies, from cutaneous lesions to life-threatening sepsis... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Prajsnar TK, Serba JJ, Dekker BM, Gibson JF, Masud S, Fleming A, Johnston SA, Renshaw SA, Meijer AH. The autophagic response to Staphylococcus aureus provides an intracellular niche in neutrophils. Autophagy. 2020;[Epub] doi:10.1080/15548627.2020.1739443. |
FXR1 splicing is important for muscle development and biomolecular condensates in muscle cells
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Citation:
J Cell Biol. 2020;219(4):e201911129. doi:10.1083/jcb.201911129 Epub:
Yes Abstract:
Fragile-X mental retardation autosomal homologue-1 (FXR1) is a muscle-enriched RNA-binding protein. FXR1 depletion is... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Smith JA, Curry EG, Blue RE, Roden C, Dundon SER, Rodríguez-Vargas A, Jordan DC, Chen X, Lyons SM, Crutchley J, Anderson P, Horb ME, Gladfelter AS , Giudice J. FXR1 splicing is important for muscle development and biomolecular condensates in muscle cells. J Cell Biol. 2020;219(4):e201911129. doi:10.1083/jcb.201911129. |
Genetic Compensation of γ CaMKII, an Evolutionarily Conserved Gene
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Citation:
Gene. 2020 Mar 9:144567. doi: 10.1016/j.gene.2020.144567. [Epub ahead of print] Epub:
Yes Abstract:
CaMKII is a Ca2+/CaM-dependent protein kinase encoded by a family of conserved genes found throughout all metazoan species and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rothschild SC, Ingram SR, Lu FI, Thisse B, Thisse C, Parkerson JA, Tombes RM. Genetic Compensation of γ CaMKII, an Evolutionarily Conserved Gene. Gene. 2020 Mar 9:144567. doi: 10.1016/j.gene.2020.144567. [Epub ahead of print]. |
The zebrafish Znt1asa17 mutant reveals roles of zinc transporter-1a in embryonic development
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Citation:
J Trace Elem Med Bio. 2020 Mar 12;60:126496. doi: 10.1016/j.jtemb.2020.126496. [Epub ahead of print] Epub:
Not Epub Abstract:
Background: Zinc is one of the vital micronutrients required through various developmental stages in animals. Zinc transporter-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Muraina IA, Bury NR, Scott A, Graham A, Hogstrand C. The zebrafish Znt1asa17 mutant reveals roles of zinc transporter-1a in embryonic development. J Trace Elem Med Bio. 2020 Mar 12;60:126496. doi: 10.1016/j.jtemb.2020.126496. [Epub ahead of print]. |
miR-7 Controls the Dopaminergic/Oligodendroglial Fate through Wnt/β-catenin Signaling Regulation
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Citation:
Cells. 2020;9(3):2073-4409 doi:10.3390/cells9030711 Epub:
Not Epub Abstract:
During the development of the central nervous system, the proliferation of neural progenitors and differentiation of neurons... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Adusumilli L, Facchinello N, Teh C, Busolin G, Le TM, Yang H, Beffagna G, Campanaro S, Tam LW, Argenton F, Lim B, Korzh V, Tiso N. miR-7 Controls the Dopaminergic/Oligodendroglial Fate through Wnt/β-catenin Signaling Regulation. Cells. 2020;9(3):2073-4409 doi:10.3390/cells9030711. |
Increased dystrophin production with golodirsen in patients with Duchenne muscular dystrophy
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Citation:
Neurology. 2020 Mar 5. pii: 10.1212/WNL.0000000000009233. doi: 10.1212/WNL.0000000000009233. [Epub ahead of print] Epub:
Yes Abstract:
Objective: To report safety, pharmacokinetics, exon 53 skipping, and dystrophin expression in golodirsen-treated patients with... Delivery Method:
i.v. infusion Organism or Cell Type:
human Citation Extract: Frank DE, Schnell FJ, Akana C, El-Husayni SH, Desjardins CA, Morgan J, Charleston JS, Sardone V, Domingos J, Dickson G, Straub V, Guglieri M, Mercuri E, Servais L, Muntoni F; SKIP-NMD Study Group. Increased dystrophin production with golodirsen in patients with Duchenne muscular dystrophy. Neurology. 2020 Mar 5. pii: 10.1212/WNL.0000000000009233. doi: 10.1212/WNL.0000000000009233. [Epub ahead of print]. |