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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Early inflammation dysregulates neuronal circuit formation in vivo via upregulation of IL-1β
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Citation:
J Neurosci. 2021 Jun 8:JN-RM-2159-20. doi: 10.1523/JNEUROSCI.2159-20.2021. Online ahead of print Epub:
Yes Abstract:
Neuro-immune interaction during development is strongly implicated in the pathogenesis of neurodevelopmental disorders, but the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Solek CM, Farooqi NAI, Brake N, Kesner P, Schohl A, Antel JP, Ruthazer ES. Early inflammation dysregulates neuronal circuit formation in vivo via upregulation of IL-1β. J Neurosci. 2021 Jun 8:JN-RM-2159-20. doi: 10.1523/JNEUROSCI.2159-20.2021. Online ahead of print. |
Notch signaling via Hey1 and Id2b regulates Müller glia’s regenerative response to retinal injury
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.03.11.435053 Epub:
Not Epub Abstract:
Zebrafish Müller glia (MG) respond to retinal injury by suppressing Notch signaling and producing progenitors for retinal... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sahu A, Devi S, Jui J, Goldman D. Notch signaling via Hey1 and Id2b regulates Müller glia’s regenerative response to retinal injury. bioRxiv. 2021;[preprint] doi:10.1101/2021.03.11.435053. |
A precise regulation of presenilin expression is required for the sea urchin early development
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Citation:
J Cell Sci. 2021;jcs.258382. doi:10.1242/jcs.258382 Epub:
Not Epub Abstract:
Presenilins or PSENs homologues are widely expressed across eukaryotes. Two PSEN are expressed in humans where they play a... Organism or Cell Type:
sea urchin Citation Extract: Bronchain O, Philippe-Caraty L, Anquetil V, Ciapa B. A precise regulation of presenilin expression is required for the sea urchin early development. J Cell Sci. 2021;jcs.258382. doi:10.1242/jcs.258382. |
Three-dimensional folding dynamics of the Xenopus tropicalis genome
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Citation:
Nat Genet. 2021;[Epub ahead of print] doi:10.1038/s41588-021-00878-z Epub:
Yes Abstract:
Animal interphase chromosomes are organized into topologically associating domains (TADs). How TADs are formed is not fully... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Niu L, Shen W, Shi Z, Tan Y, He N, Wan J, Sun J, Zhang Y, Huang Y, Wang W, Fang C, Li J, Zheng P, Cheung E, Chen Y, Li L, Hou C. Three-dimensional folding dynamics of the Xenopus tropicalis genome. Nat Genet. 2021;[Epub ahead of print] doi:10.1038/s41588-021-00878-z. |
Self-transfecting GMO-PMO and PMO-GMO chimeras enable gene silencing in vitro and in vivo zebrafish model and NANOG Inhibition Induce the Apoptosis in Breast and Prostate Cancer Cells
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.06.04.447039 Epub:
Not Epub Abstract:
Phosphorodiamidate Morpholino Oligonucleotides (PMOs)-based antisense reagents cannot enter inside cells by itself without the... Delivery Method:
guanidinium-morpholino and Morpholino chimeras Organism or Cell Type:
cell culture: Shh-Light 2, MCF7, PC-3, MDA MB-231, Shh-N; zebrafish Citation Extract: Kundu J, Das U, Bose C, Bhadra J, Sinha S. Self-transfecting GMO-PMO and PMO-GMO chimeras enable gene silencing in vitro and in vivo zebrafish model and NANOG Inhibition Induce the Apoptosis in Breast and Prostate Cancer Cells. bioRxiv. 2021;[preprint] doi:10.1101/2021.06.04.447039. |
Discovery of a pre-mRNA structural scaffold as a contributor to the mammalian splicing code
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/292458 Epub:
Not Epub Abstract:
The specific recognition of splice signals at or near exon-intron junctions is not explained by their weak conservation and... Organism or Cell Type:
cell culture: HeLa Citation Extract: Saha K, Fernandez MM, Biswas T, Joseph S, Ghosh G. Discovery of a pre-mRNA structural scaffold as a contributor to the mammalian splicing code. bioRxiv. 2021;[preprint] doi:10.1101/292458 . |
Distinct spatiotemporal contribution of morphogenetic events and mechanical tissue coupling during Xenopus neural tube closure
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.06.01.446407 Epub:
Not Epub Abstract:
Neural tube closure (NTC) is a fundamental process during vertebrate embryonic development and is indispensable for the... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Christodoulou N, Skourides PA. Distinct spatiotemporal contribution of morphogenetic events and mechanical tissue coupling during Xenopus neural tube closure. bioRxiv. 2021;[preprint] doi:10.1101/2021.06.01.446407 . |
[Donepezil Reduces Amyloid Precursor Protein Endocytosis by Resulting from Increase in the Expression of Sorting Nexin Protein 33]
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Citation:
Yakugaku Zasshi. 2021;141(6):851-856. doi:10.1248/yakushi.20-00251-6 Epub:
Not Epub Abstract:
Donepezil, the most widely used drug for the treatment of Alzheimer's disease (AD), is an acetylcholinesterase (AChE)... Organism or Cell Type:
cell culture: primary fetal rat cortical neurons Citation Extract: Takada-Takatori Y. [Donepezil Reduces Amyloid Precursor Protein Endocytosis by Resulting from Increase in the Expression of Sorting Nexin Protein 33]. Yakugaku Zasshi. 2021;141(6):851-856. doi:10.1248/yakushi.20-00251-6. |
Masculinization of Zebrafish Through Partial Depletion of Primordial Germ Cells by Injecting Diluted Morpholino Oligonucleotides into Embryos
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Citation:
In: Dosch R. (eds) Germline Development in the Zebrafish. Methods in Molecular Biology. 2021;2218. Humana, New York, NY. doi:10.1007/978-1-0716-0970-5_5 Epub:
Not Epub Abstract:
The regulation of reproduction in zebrafish, the prime model of fish research, is not fully understood. An efficient tool to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Orbán L, Saju JM, Tzung KW, Liew WC. Masculinization of Zebrafish Through Partial Depletion of Primordial Germ Cells by Injecting Diluted Morpholino Oligonucleotides into Embryos. In: Dosch R. (eds) Germline Development in the Zebrafish. Methods in Molecular Biology. 2021;2218. Humana, New York, NY. doi:10.1007/978-1-0716-0970-5_5. |
Myeloid-derived growth factor regulates neutrophil motility in interstitial tissue damage
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Citation:
J Cell Biol. 2021;220(8):e202103054. Epub ahead of print. doi:10.1083/jcb.202103054 Epub:
Not Epub Abstract:
Neutrophil recruitment to tissue damage is essential for host defense but can also impede tissue repair. The cues that... Organism or Cell Type:
zebrafish Citation Extract: Houseright RA, Miskolci V, Mulvaney O, Bortnov V, Mosher DF, Rindy J, Bennin DA, Huttenlocher A. Myeloid-derived growth factor regulates neutrophil motility in interstitial tissue damage. J Cell Biol. 2021;220(8):e202103054. Epub ahead of print. doi:10.1083/jcb.202103054. |