You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12419 scientific papers returned from the database with the search filters currently being used below.

SLM2 Is A Novel Cardiac Splicing Factor Involved in Heart Failure due to Dilated Cardiomyopathy

Authors:
Boeckel J-N, Möbius-Winkler M, Müller M, Rebs S, Eger N, Schoppe L, Tappu R, Kokot KE, Kneuer JM, Gaul S, Bordalo DM, Lai A, Haas J, Ghanbari M, Drewe-Boss P, Liss M, Katus HA, Ohler U, Gotthardt M, Laufs U, Streckfuss-Bömeke K, Meder B
Citation:
Genomics Proteomics Bioinformatics. 2021;[Epub ahead of print] doi:10.1016/j.gpb.2021.01.006
Epub:
Yes
Abstract:
Alternative mRNA splicing is a fundamental process to increase the versatility of the genome. In humans, cardiac mRNA splicing...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Boeckel J-N, Möbius-Winkler M, Müller M, Rebs S, Eger N, Schoppe L, Tappu R, Kokot KE, Kneuer JM, Gaul S, Bordalo DM, Lai A, Haas J, Ghanbari M, Drewe-Boss P, Liss M, Katus HA, Ohler U, Gotthardt M, Laufs U, Streckfuss-Bömeke K, Meder B. SLM2 Is A Novel Cardiac Splicing Factor Involved in Heart Failure due to Dilated Cardiomyopathy. Genomics Proteomics Bioinformatics. 2021;[Epub ahead of print] doi:10.1016/j.gpb.2021.01.006.

Cell adhesions link subcellular actomyosin dynamics to tissue scale force production during vertebrate convergent extension

Authors:
Huebner RJ, Weng S, Lee C, Sarıkaya S, Papoulas O, Cox RM, Marcotte EM, Wallingford JB
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.06.21.449290
Epub:
Not Epub
Abstract:
Axis extension is a fundamental biological process that shapes multicellular organisms. The design of an animal’s body plan is...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Huebner RJ, Weng S, Lee C, Sarıkaya S, Papoulas O, Cox RM, Marcotte EM, Wallingford JB. Cell adhesions link subcellular actomyosin dynamics to tissue scale force production during vertebrate convergent extension. bioRxiv. 2021;[preprint] doi:10.1101/2021.06.21.449290 .

The atypical RNA-binding protein TAF15 regulates dorsoanterior neural development through diverse mechanisms in Xenopus tropicalis

Authors:
DeJong CS, Dichmann DS, Exner CRT, Xu Y, Harland RM
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.06.14.041913
Epub:
Not Epub
Abstract:
The FET family of atypical RNA-binding proteins includes Fused in sarcoma (Fus), Ewing’s sarcoma (EWS), and the TATA-binding...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
DeJong CS, Dichmann DS, Exner CRT, Xu Y, Harland RM. The atypical RNA-binding protein TAF15 regulates dorsoanterior neural development through diverse mechanisms in Xenopus tropicalis. bioRxiv. 2021;[preprint] doi:10.1101/2021.06.14.041913 .

A prometaphase mechanism of securin destruction is essential for meiotic progression in mouse oocytes

Authors:
Thomas C, Wetherall B, Levasseur D, Harris RJ, Kerridge ST, Higgins JMG, Davies OR, Madgwick S
Citation:
Nat Commun. 2021;12(1):4322. doi:10.1038/s41467-021-24554-2
Epub:
Not Epub
Abstract:
Successful cell division relies on the timely removal of key cell cycle proteins such as securin. Securin inhibits separase,...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Thomas C, Wetherall B, Levasseur D, Harris RJ, Kerridge ST, Higgins JMG, Davies OR, Madgwick S. A prometaphase mechanism of securin destruction is essential for meiotic progression in mouse oocytes. Nat Commun. 2021;12(1):4322. doi:10.1038/s41467-021-24554-2.

Real time large scale in vivo observations by light-sheet microscopy reveal intrinsic synchrony, plasticity and growth cone dynamics of midline crossing axons at the ventral floor plate of the zebrafish spinal cord

Authors:
Andersen SSL
Citation:
arXiv. 2021;2107.05242v1 [preprint]
Epub:
Not Epub
Abstract:
Axonal growth and guidance at the ventral floor plate is here followed in vivo in real time at high resolution by light-sheet...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Andersen SSL. Real time large scale in vivo observations by light-sheet microscopy reveal intrinsic synchrony, plasticity and growth cone dynamics of midline crossing axons at the ventral floor plate of the zebrafish spinal cord. arXiv. 2021;2107.05242v1 [preprint].

Glypican 4 regulates planar cell polarity of endoderm cells by controlling the localization of Cadherin 2

Authors:
Balaraju AK, Hu B, Rodriguez JJ, Murry M, Lin F
Citation:
Development. 2021 Jul 15;148(14):dev199421. doi: 10.1242/dev.199421. Epub 2021 Jul 12
Epub:
Not Epub
Abstract:
Noncanonical Wnt/planar cell polarity (Wnt/PCP) signaling has been implicated in endoderm morphogenesis. However, the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Balaraju AK, Hu B, Rodriguez JJ, Murry M, Lin F. Glypican 4 regulates planar cell polarity of endoderm cells by controlling the localization of Cadherin 2. Development. 2021 Jul 15;148(14):dev199421. doi: 10.1242/dev.199421. Epub 2021 Jul 12.

Rab7 is required for mesoderm patterning and gastrulation in Xenopus

Authors:
Kreis J, Wielath FM, Vick P
Citation:
Biol Open. 2021 Jul 15;10(7):bio056887. doi: 10.1242/bio.056887. Epub 2021 Jul 12
Epub:
Not Epub
Abstract:
Early embryogenesis requires tightly controlled temporal and spatial coordination of cellular behavior and signaling....
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Kreis J, Wielath FM, Vick P. Rab7 is required for mesoderm patterning and gastrulation in Xenopus. Biol Open. 2021 Jul 15;10(7):bio056887. doi: 10.1242/bio.056887. Epub 2021 Jul 12.

Temporal regulation of Pten is essential for retina regeneration in zebrafish

Authors:
Gupta S, Sharma P, Chaudhary M, Premraj S, Kaur S, Vijithkumar V, Ramachandran R
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.07.09.451767
Epub:
Not Epub
Abstract:
Unlike mammals, zebrafish possess a remarkable ability to regenerate damaged retina after an acute injury. Retina regeneration...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gupta S, Sharma P, Chaudhary M, Premraj S, Kaur S, Vijithkumar V, Ramachandran R. Temporal regulation of Pten is essential for retina regeneration in zebrafish. bioRxiv. 2021;[preprint] doi:10.1101/2021.07.09.451767.

Autonomous Calcium Signaling in Human and Zebrafish Podocytes Controls Kidney Filtration Barrier Morphogenesis

Authors:
Djenoune L, Tomar R, Dorison A, Ghobrial I, Schenk H, Hegermann J, Beverly-Staggs L, Hidalgo-Gonzalez A, Little MH, Drummond IA
Citation:
J Am Soc Nephrol. 2021 Apr 28:ASN.2020101525. doi: 10.1681/ASN.2020101525. Online ahead of print
Epub:
Yes
Abstract:
Background: Podocytes are critical to maintaining the glomerular filtration barrier, and mutations in nephrotic syndrome genes...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Djenoune L, Tomar R, Dorison A, Ghobrial I, Schenk H, Hegermann J, Beverly-Staggs L, Hidalgo-Gonzalez A, Little MH, Drummond IA. Autonomous Calcium Signaling in Human and Zebrafish Podocytes Controls Kidney Filtration Barrier Morphogenesis. J Am Soc Nephrol. 2021 Apr 28:ASN.2020101525. doi: 10.1681/ASN.2020101525. Online ahead of print.

The Rac-GAP alpha2-chimaerin signals via CRMP2 and stathmins in the development of the ocular motor system

Authors:
Carretero-Rodriguez L, Guðjónsdóttir R, Poparic I, Reilly ML, Chol M, Bianco IH, Chiapello M, Feret R, Deery MJ, Guthrie S
Citation:
J Neurosci. 2021;41(31):6652-6672. doi: 10.1523/JNEUROSCI.0983-19.2021. Online ahead of print
Epub:
Not Epub
Abstract:
A precise sequence of axon guidance events is required for the development of the ocular motor system. Three cranial nerves...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Carretero-Rodriguez L, Guðjónsdóttir R, Poparic I, Reilly ML, Chol M, Bianco IH, Chiapello M, Feret R, Deery MJ, Guthrie S. The Rac-GAP alpha2-chimaerin signals via CRMP2 and stathmins in the development of the ocular motor system. J Neurosci. 2021;41(31):6652-6672. doi: 10.1523/JNEUROSCI.0983-19.2021. Online ahead of print.

Pages