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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Nuclear-cytoplasmic compartmentalization promotes robust timing of mitotic events by cyclin B1-Cdk1

Authors:
Maryu G, Yang Q
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.07.28.454130
Epub:
Not Epub
Abstract:
Studies applying well-mixed cytosolic extracts found the mitotic network centered on cyclin-dependent kinase (Cdk1) performs...
Link:
https://www.biorxiv.org/content/10.1101/2021.07.28.454130v1
Organism or Cell Type:
Xenopus
Citation Extract:
Maryu G, Yang Q. Nuclear-cytoplasmic compartmentalization promotes robust timing of mitotic events by cyclin B1-Cdk1. bioRxiv. 2021;[preprint] doi:10.1101/2021.07.28.454130 .

Hemagglutinins of Avian Influenza Viruses Are Proteolytically Activated by TMPRSS2 in Human and Murine Airway Cells

Authors:
Bestle D, Limburg H, Kruhl D, Harbig A, Stein DA, Moulton H, Matrosovich M, Abdelwhab EM, Stech J, Böttcher-Friebertshäuser E
Citation:
J Virol. 2021 Sep 27;95(20):e0090621. doi: 10.1128/JVI.00906-21. Epub 2021 Jul 28. PMID: 34319155; PMCID: PMC8475512
Epub:
Not Epub
Abstract:
Cleavage of the influenza A virus (IAV) hemagglutinin (HA) by host proteases is indispensable for virus replication. Most IAVs...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC8475512/
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: human and mouse airway cells
Citation Extract:
Bestle D, Limburg H, Kruhl D, Harbig A, Stein DA, Moulton H, Matrosovich M, Abdelwhab EM, Stech J, Böttcher-Friebertshäuser E. Hemagglutinins of Avian Influenza Viruses Are Proteolytically Activated by TMPRSS2 in Human and Murine Airway Cells. J Virol. 2021 Sep 27;95(20):e0090621. doi: 10.1128/JVI.00906-21. Epub 2021 Jul 28. PMID: 34319155; PMCID: PMC8475512.

Role of the cardiovascular system in ammonia excretion in early life stages of zebrafish (Danio rerio)

Authors:
Wang Y, Pasparakis C, Grosell M
Citation:
Am J Physiol Regul Integr Comp Physiol. 2021 Jul 28. doi: 10.1152/ajpregu.00284.2020. Online ahead of print
Epub:
Yes
Abstract:
The purpose of this study was to investigate if the cardiovascular system is important for ammonia excretion in the early life...
Link:
https://journals.physiology.org/doi/abs/10.1152/ajpregu.00284.2020
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang Y, Pasparakis C, Grosell M. Role of the cardiovascular system in ammonia excretion in early life stages of zebrafish (Danio rerio). Am J Physiol Regul Integr Comp Physiol. 2021 Jul 28. doi: 10.1152/ajpregu.00284.2020. Online ahead of print.

LAMP2A regulates the loading of proteins into exosomes

Authors:
Ferreira JV, da Rosa Soares A, Ramalho J, Carvalho CM, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.07.26.453637
Epub:
Not Epub
Abstract:
Exosomes are extracellular vesicles of endosomal origin released by virtually all cell types across metazoans. Exosomes are...
Link:
https://www.biorxiv.org/content/10.1101/2021.07.26.453637v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ferreira JV, da Rosa Soares A, Ramalho J, Carvalho CM, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P. LAMP2A regulates the loading of proteins into exosomes. bioRxiv. 2021;[preprint] doi:10.1101/2021.07.26.453637 .

Extracellular mechanical forces drive endocardial cell volume decrease during cardiac valve morphogenesis

Authors:
Vermot J, Vignes H, Vagena-Pantoula C, Prakash M, Norden C, Jug F
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.07.27.453460
Epub:
Not Epub
Abstract:
Organ morphogenesis involves dynamic changes of tissue properties at the cellular scale. In addition, cells need to adapt to...
Link:
https://www.biorxiv.org/content/10.1101/2021.07.27.453460v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Vermot J, Vignes H, Vagena-Pantoula C, Prakash M, Norden C, Jug F. Extracellular mechanical forces drive endocardial cell volume decrease during cardiac valve morphogenesis. bioRxiv. 2021;[preprint] doi:10.1101/2021.07.27.453460 .

Paracrine regulation of neural crest EMT by placodal MMP28

Authors:
Gouignard N, Bibonne A, Mata JF, Bajanca F, Berki B, Barriga EH, Saint-Jeannet J-P, Theveneau E
Citation:
bioRxiv. 2020;[preprint]. doi:10.1101/2020.11.19.389544
Epub:
Not Epub
Abstract:
Epithelial-Mesenchymal Transition (EMT) is an early event in cell dissemination from epithelial tissues. EMT endows cells with...
Link:
https://www.biorxiv.org/content/10.1101/2020.11.19.389544v2
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Gouignard N, Bibonne A, Mata JF, Bajanca F, Berki B, Barriga EH, Saint-Jeannet J-P, Theveneau E. Paracrine regulation of neural crest EMT by placodal MMP28. bioRxiv. 2020;[preprint]. doi:10.1101/2020.11.19.389544 .

Knockdown screening of chromatin binding and regulatory proteins in zebrafish identified Suz12b as a regulator of tfpia and an antithrombotic drug target

Authors:
Raman R, Fallatah W, Al Qaryoute A, Dhinoja S, Jagadeeswaran P
Citation:
Sci Rep. 2021 Jul 27;11(1):15238. doi: 10.1038/s41598-021-94715-2
Epub:
Not Epub
Abstract:
Tissue factor pathway inhibitor (TFPI) is an anticoagulant protein that inhibits factor VIIa and Xa in the coagulation cascade...
Link:
https://www.nature.com/articles/s41598-021-94715-2
Delivery Method:
Vivo-Morpholino piggyback hybrid
Organism or Cell Type:
zebrafish
Citation Extract:
Raman R, Fallatah W, Al Qaryoute A, Dhinoja S, Jagadeeswaran P. Knockdown screening of chromatin binding and regulatory proteins in zebrafish identified Suz12b as a regulator of tfpia and an antithrombotic drug target. Sci Rep. 2021 Jul 27;11(1):15238. doi: 10.1038/s41598-021-94715-2.

Blood flow coordinates collective endothelial cell migration during vascular plexus formation and promotes angiogenic sprout regression via vegfr3/flt4

Authors:
Chen Y, Jiang Z, Fisher KH, Kim HR, Evans PC, Wilkinson RN
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.07.23.453496
Epub:
Not Epub
Abstract:
Nascent vascular networks adapt to the increasing metabolic demands of growing tissues by expanding via angiogenesis. As...
Link:
https://www.biorxiv.org/content/10.1101/2021.07.23.453496v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen Y, Jiang Z, Fisher KH, Kim HR, Evans PC, Wilkinson RN. Blood flow coordinates collective endothelial cell migration during vascular plexus formation and promotes angiogenic sprout regression via vegfr3/flt4. bioRxiv. 2021;[preprint] doi:10.1101/2021.07.23.453496 .

Systematic mapping of small nucleolar RNA targets in human cells

Authors:
Dunn-Davies H, Dudnakova T, Langhendries J-L, Watkins N, Lafontaine DLJ, Tollervey D
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.07.22.451324
Epub:
Not Epub
Abstract:
Altered expression of box C/D small nucleolar RNAs (snoRNAs) is implicated in human diseases, including cancer. Box C/D snoRNAs...
Link:
https://www.biorxiv.org/content/10.1101/2021.07.22.451324v1
Organism or Cell Type:
cell culture: HEK
Citation Extract:
Dunn-Davies H, Dudnakova T, Langhendries J-L, Watkins N, Lafontaine DLJ, Tollervey D. Systematic mapping of small nucleolar RNA targets in human cells. bioRxiv. 2021;[preprint] doi:10.1101/2021.07.22.451324.

A connexin/ifi30 pathway bridges HSCs with their niche to dampen oxidative stress

Authors:
Cacialli P, Mahony CB, Petzold T, Bordignon P, Rougemont A-L, Bertrand JY
Citation:
Nat Commun. 2021;12(1):4484. doi:10.1038/s41467-021-24831-0
Epub:
Not Epub
Abstract:
Reactive oxygen species (ROS) represent a by-product of metabolism and their excess is toxic for hematopoietic stem and...
Link:
https://www.nature.com/articles/s41467-021-24831-0
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cacialli P, Mahony CB, Petzold T, Bordignon P, Rougemont A-L, Bertrand JY. A connexin/ifi30 pathway bridges HSCs with their niche to dampen oxidative stress. Nat Commun. 2021;12(1):4484. doi:10.1038/s41467-021-24831-0.

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