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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Zebrafish Cdx4 regulates neural crest cell specification and migratory behaviors in the posterior body
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Citation:
Dev Bio. 2021;[Epub} doi:10.1016/j.ydbio.2021.08.002 Epub:
Not Epub Abstract:
The neural crest (NC) is a transient multipotent cell population that migrates extensively to produce a remarkable array of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rocha M, Kushkowski E, Schnirman R, Booth C, Singh N, Beadell A, Prince VE. Zebrafish Cdx4 regulates neural crest cell specification and migratory behaviors in the posterior body. Dev Bio. 2021;[Epub} doi:10.1016/j.ydbio.2021.08.002. |
Open reading frame correction using antisense oligonucleotides for the treatment of cystic fibrosis caused by CFTR-W1282X
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.08.11.455834 Epub:
Not Epub Abstract:
CFTR gene mutations that result in the introduction of premature termination codons (PTCs) are common in cystic fibrosis (CF).... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: CFTR-W1282X bronchial epithelial line, primary CFTR-W1282X epithelial cells Citation Extract: Michaels WE, Pena-Rasgado C, Kotaria R, Bridges RJ, Hastings ML. Open reading frame correction using antisense oligonucleotides for the treatment of cystic fibrosis caused by CFTR-W1282X. bioRxiv. 2021;[preprint] doi:10.1101/2021.08.11.455834. |
Dietary Nucleotides Alleviate Hepatic Lipid Deposition via Exogenous AMP-Mediated AMPK Activation in Zebrafish
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Citation:
J Nutr. 2021;nxab232 {Epub] doi:doi.org/10.1093/jn/nxab232 Epub:
Yes Abstract:
Background: Dietary nucleotides (NTs) have been reported to affect hepatic function and composition. However, the effects on... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
zebrafish Citation Extract: Ran C, Xie M, Li J, Xie Y, Ding Q, Li Y, Zhou W, Yang Y, Zhang Z, Olsen RE, Zhou Z. Dietary Nucleotides Alleviate Hepatic Lipid Deposition via Exogenous AMP-Mediated AMPK Activation in Zebrafish. J Nutr. 2021;nxab232 {Epub] doi:doi.org/10.1093/jn/nxab232. |
DNA-damage induced cell death in yap1;wwtr1 mutant epidermal basal cells
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.07.23.453490 Epub:
Not Epub Abstract:
In a previous study, it was reported that Yap1 and Wwtr1 in zebrafish regulates the morphogenesis of the posterior body and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lai JKH, Toh PJY, Cognart HA, Chouhan G, Saunders TE. DNA-damage induced cell death in yap1;wwtr1 mutant epidermal basal cells. bioRxiv. 2021;[preprint] doi:10.1101/2021.07.23.453490. |
Zic1 advances epaxial myotome morphogenesis to cover the neural tube via Wnt11r
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Citation:
bioRxiv. 20219;[preprint] doi:/10.1101/2021.07.12.452069 Epub:
Not Epub Abstract:
The dorsal axial muscles, or epaxial muscles, are a fundamental structure covering the spinal cord and vertebrae, as well as... Delivery Method:
microinjection Organism or Cell Type:
Oryzias latipes (medaka) Citation Extract: Heilig AK, Nakamura R, Shimada A, Hashimoto Y, Nakamura Y, Wittbrodt J, Takeda H, Kawanishi T. Zic1 advances epaxial myotome morphogenesis to cover the neural tube via Wnt11r. bioRxiv. 20219;[preprint] doi:/10.1101/2021.07.12.452069. |
The E3 Ubiquitin Ligase Mindbomb1 controls zebrafish Planar Cell Polarity
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.07.05.451064 Epub:
Not Epub Abstract:
Vertebrate Delta/Notch signaling involves multiple ligands, receptors and transcription factors. Delta endocytosis – a critical... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Saraswathy VM, Sharma P, Kurup AJ, Polès S, Poulain M, Fürthauer M. The E3 Ubiquitin Ligase Mindbomb1 controls zebrafish Planar Cell Polarity. bioRxiv. 2021;[preprint] doi:10.1101/2021.07.05.451064 . |
Fluorescence Correlation Spectroscopy Reveals Survival Motor Neuron Oligomerization but No Active Transport in Motor Axons of a Zebrafish Model for Spinal Muscular Atrophy
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Citation:
Front Cell Dev Biol. 2021;9:639904. doi:10.3389/fcell.2021.639904 Epub:
Not Epub Abstract:
Spinal Muscular Atrophy (SMA) is a progressive neurodegenerative disease affecting lower motor neurons that is caused by a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Koh A, Sarusie MV, Ohmer J, Fischer U, Winkler C and Wohland T. Fluorescence Correlation Spectroscopy Reveals Survival Motor Neuron Oligomerization but No Active Transport in Motor Axons of a Zebrafish Model for Spinal Muscular Atrophy. Front Cell Dev Biol. 2021;9:639904. doi:10.3389/fcell.2021.639904. |
A ligand-insensitive UNC5B splicing isoform regulates angiogenesis by promoting apoptosis
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Citation:
Nat Comm. 2021;12(1):4872. doi:10.1038/s41467-021-24998-6 Epub:
Not Epub Abstract:
The Netrin-1 receptor UNC5B is an axon guidance regulator that is also expressed in endothelial cells (ECs), where it finely... Delivery Method:
Endo-Porter, microinjection Organism or Cell Type:
cell culture: HUVEC/TERT2, zebrafish Citation Extract: Pradella D, Deflorian G, Pezzotta A, Di Matteo A, Belloni E, Campolungo D, Paradisi A, Bugatti M, Vermi W, Campioni M, Chiapparino A, Scietti L, Forneris F, Giampietro C, Volf N, Rehman M, Zacchigna S, Paronetto MP, Pistocchi A, Eichmann A, Mehlen P, Ghigna C. A ligand-insensitive UNC5B splicing isoform regulates angiogenesis by promoting apoptosis. Nat Comm. 2021;12(1):4872. doi:10.1038/s41467-021-24998-6. |
The miR-430 locus with extreme promoter density forms a transcription body during the minor wave of zygotic genome activation
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Citation:
Dev Cell. 2023 Jan 23;58(2):155-170.e8. doi: 10.1016/j.devcel.2022.12.007. PMID: 36693321; PMCID: PMC9904021 Epub:
Not Epub Abstract:
In anamniote embryos, the major wave of zygotic genome activation starts during the mid-blastula transition. However, some... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hadzhiev Y, Wheatley L, Cooper L, Ansaloni F, Whalley C, Chen Z, Finaurini S, Gustincich S, Sanges R, Burgess S, Beggs A, Müller F. The miR-430 locus with extreme promoter density forms a transcription body during the minor wave of zygotic genome activation. Dev Cell. 2023 Jan 23;58(2):155-170.e8. doi: 10.1016/j.devcel.2022.12.007. PMID: 36693321; PMCID: PMC9904021. |
Twisting of the zebrafish heart tube during cardiac looping is a tbx5-dependent and tissue-intrinsic process
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Citation:
Elife. 2021 Aug 10;10:e61733. doi: 10.7554/eLife.61733 Epub:
Not Epub Abstract:
Organ laterality refers to the left-right asymmetry in disposition and conformation of internal organs and is established... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tessadori F, Tsingos E, Colizzi ES, Kruse F, van den Brink SC, van den Boogaard M, Christoffels VM, Merks RM, Bakkers J. Twisting of the zebrafish heart tube during cardiac looping is a tbx5-dependent and tissue-intrinsic process. Elife. 2021 Aug 10;10:e61733. doi: 10.7554/eLife.61733. |