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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Deficiency of the cytoskeletal protein SPECC1L leads to oblique facial clefting

Authors:
Saadi I, Alkuraya FS, Gisselbrecht SS, Goessling W, Cavallesco R, Turbe-Doan A, Petrin AL, Harris J, Siddiqui U, Grix AW Jr, Hove HD, Leboulch P, Glover TW, Morton CC, Richieri-Costa A, Murray JC, Erickson RP, Maas RL
Citation:
Am J Hum Genet. 2011 Jul 15;89(1):44-55. Epub 2011 Jun 23
Epub:
Not Epub
Abstract:
Genetic mutations responsible for oblique facial clefts (ObFC), a unique class of facial malformations, are largely unknown. We...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Saadi I, Alkuraya FS, Gisselbrecht SS, Goessling W, Cavallesco R, Turbe-Doan A, Petrin AL, Harris J, Siddiqui U, Grix AW Jr, Hove HD, Leboulch P, Glover TW, Morton CC, Richieri-Costa A, Murray JC, Erickson RP, Maas RL. Deficiency of the cytoskeletal protein SPECC1L leads to oblique facial clefting. Am J Hum Genet. 2011 Jul 15;89(1):44-55. Epub 2011 Jun 23.

Depletion of minichromosome maintenance protein 5 in the zebrafish retina causes cell-cycle defect and apoptosis

Authors:
Ryu S, Holzschuh J, Erhardt S, Ettl AK, Driever W
Citation:
Proc Natl Acad Sci U S A. 2005 Dec 20;102(51):18467-72. Epub 2005 Dec 8
Epub:
Not Epub
Abstract:
In multicellular organisms, the control of genome duplication and cell division must be tightly coordinated. Essential roles of...
Organism or Cell Type:
zebrafish
Citation Extract:
Ryu S, Holzschuh J, Erhardt S, Ettl AK, Driever W. Depletion of minichromosome maintenance protein 5 in the zebrafish retina causes cell-cycle defect and apoptosis. Proc Natl Acad Sci U S A. 2005 Dec 20;102(51):18467-72. Epub 2005 Dec 8.

Disruption of acvrl1 increases endothelial cell number in zebrafish cranial vessels

Authors:
Roman BL, Pham VN, Lawson ND, Kulik M, Childs S, Lekven AC, Garrity DM, Moon RT, Fishman MC, Lechleider RJ, Weinstein BM
Citation:
Development. 2002 Jun;129(12):3009-19
Epub:
Not Epub
Abstract:
The zebrafish mutant violet beauregarde (vbg) can be identified at two days post-fertilization by an abnormal circulation...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Roman BL, Pham VN, Lawson ND, Kulik M, Childs S, Lekven AC, Garrity DM, Moon RT, Fishman MC, Lechleider RJ, Weinstein BM. Disruption of acvrl1 increases endothelial cell number in zebrafish cranial vessels. Development. 2002 Jun;129(12):3009-19.

Distinct roles for telethonin N-versus C-terminus in sarcomere assembly and maintenance

Authors:
Sadikot T, Hammond CR, Ferrari MB
Citation:
Dev Dyn. 2010 Mar 16;239(4):1124-1135. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The N-terminus of telethonin forms a unique structure linking two titin N-termini at the Z-disc. While a specific role for the...
Organism or Cell Type:
Xenopus
Citation Extract:
Sadikot T, Hammond CR, Ferrari MB. Distinct roles for telethonin N-versus C-terminus in sarcomere assembly and maintenance. Dev Dyn. 2010 Mar 16;239(4):1124-1135. [Epub ahead of print].

Dopaminergic neuronal cluster size is determined during early forebrain patterning

Authors:
Russek-Blum N, Gutnick A, Nabel-Rosen H, Blechman J, Staudt N, Dorsky RI, Houart C, Levkowitz G
Citation:
Development. 2008 Oct;135(20):3401-13. Epub 2008 Sep 17
Epub:
Not Epub
Abstract:
We have explored the effects of robust neural plate patterning signals, such as canonical Wnt, on the differentiation and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Russek-Blum N, Gutnick A, Nabel-Rosen H, Blechman J, Staudt N, Dorsky RI, Houart C, Levkowitz G. Dopaminergic neuronal cluster size is determined during early forebrain patterning. Development. 2008 Oct;135(20):3401-13. Epub 2008 Sep 17.

Down-regulation of SNAIL suppresses MIN mouse tumorigenesis: Modulation of apoptosis, proliferation, and fractal dimension

Authors:
Roy HK, Iversen P, Hart J, Liu Y, Koetsier JL, Kim Y, Kunte DP, Madugula M, Backman V, Wali RK
Citation:
Mol Cancer Ther. 2004 Sep;3(9):1159-65
Epub:
Not Epub
Abstract:
Objectives: Emerging evidence implicates the SNAIL family of transcriptional repressors in cancer development; however, the...
Delivery Method:
in vivo: injection
Organism or Cell Type:
C57BL6 APCmin mice
Citation Extract:
Roy HK, Iversen P, Hart J, Liu Y, Koetsier JL, Kim Y, Kunte DP, Madugula M, Backman V, Wali RK. Down-regulation of SNAIL suppresses MIN mouse tumorigenesis: Modulation of apoptosis, proliferation, and fractal dimension. Mol Cancer Ther. 2004 Sep;3(9):1159-65.

Embryonically Expressed GABA and Glutamate Drive Electrical Activity Regulating Neurotransmitter Specification

Authors:
Root CM, Velázquez-Ulloa NA, Monsalve GC, Minakova E, Spitzer NC
Citation:
J Neurosci. 2008 Apr 30;28(18):4777-84
Epub:
Not Epub
Abstract:
Neurotransmitter signaling in the mature nervous system is well understood, but the functions of transmitters in the immature...
Citation Extract:
Root CM, Velázquez-Ulloa NA, Monsalve GC, Minakova E, Spitzer NC. Embryonically Expressed GABA and Glutamate Drive Electrical Activity Regulating Neurotransmitter Specification. J Neurosci. 2008 Apr 30;28(18):4777-84.

Endo16 is required for gastrulation in the sea urchin Lytechinus variegatus

Authors:
Romano LA, Wray GA
Citation:
Dev Growth Differ. 2006 Oct;48(8):487-497
Epub:
Not Epub
Abstract:
The Endo16 gene encodes a large extracellular protein with several functional domains that provide some insight into the role...
Delivery Method:
Microinjection
Organism or Cell Type:
Lytechinus variegatus (sea urchin)
Citation Extract:
Romano LA, Wray GA. Endo16 is required for gastrulation in the sea urchin Lytechinus variegatus. Dev Growth Differ. 2006 Oct;48(8):487-497.

Endosomolysis by Masking of a Membrane-Active Agent (EMMA) for Cytoplasmic Release of Macromolecules

Authors:
Rozema DB, Ekena K, Lewis DL, Loomis AG, Wolff JA
Citation:
Bioconjug Chem. 2003 Jan-Feb;14(1):51
Epub:
Not Epub
Abstract:
Endosomolysis, a critical barrier to efficient delivery of macromolecules such as nucleic acids, has been breached using a...
Delivery Method:
peptide-based
Organism or Cell Type:
cell culture: HeLa AntisenseTest System
Citation Extract:
Rozema DB, Ekena K, Lewis DL, Loomis AG, Wolff JA. Endosomolysis by Masking of a Membrane-Active Agent (EMMA) for Cytoplasmic Release of Macromolecules. Bioconjug Chem. 2003 Jan-Feb;14(1):51.

EphrinB/EphB Signaling Controls Embryonic Germ Layer Separation by Contact-Induced Cell Detachment

Authors:
Rohani N, Canty L, Luu O, Fagotto F, Winklbauer R
Citation:
PLoS Biol. 2011;9(3):e1000597. doi:10.1371/journal.pbio.1000597
Epub:
Not Epub
Abstract:
Background The primordial organization of the metazoan body is achieved during gastrulation by the establishment of the germ...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Rohani N, Canty L, Luu O, Fagotto F, Winklbauer R. EphrinB/EphB Signaling Controls Embryonic Germ Layer Separation by Contact-Induced Cell Detachment. PLoS Biol. 2011;9(3):e1000597. doi:10.1371/journal.pbio.1000597.

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