You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

MBD4 and MLH1 are required for apoptotic induction in xDNMT1-depleted embryos

Authors:
Ruzov A, Shorning B, Mortusewicz O, Dunican DS, Leonhardt H, Meehan RR
Citation:
Development. 2009 Jul;136(13):2277-86
Epub:
Not Epub
Abstract:
Loss of the of the maintenance methyltransferase xDNMT1 during Xenopus development results in premature transcription and...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Ruzov A, Shorning B, Mortusewicz O, Dunican DS, Leonhardt H, Meehan RR. MBD4 and MLH1 are required for apoptotic induction in xDNMT1-depleted embryos. Development. 2009 Jul;136(13):2277-86.

Melk-like kinase plays a role in hematopoiesis in the zebra fish

Authors:
Saito R, Tabata Y, Muto A, Arai K, Watanabe S
Citation:
Mol Cell Biol. 2005 Aug;25(15):6682-93
Epub:
Not Epub
Abstract:
A serine/threonine kinase, Melk, was initially cloned in mouse oocytes as a maternal gene, but whose function was unknown. In...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Saito R, Tabata Y, Muto A, Arai K, Watanabe S. Melk-like kinase plays a role in hematopoiesis in the zebra fish. Mol Cell Biol. 2005 Aug;25(15):6682-93.

Microinjection of zebrafish embryos to analyze gene function

Authors:
Rosen JN, Sweeney MF, Mably JD
Citation:
J Vis Exp. 2009 Mar 9;(25). pii: 1115. doi: 10.3791/1115.
Epub:
Not Epub
Abstract:
One of the advantages of studying zebrafish is the ease and speed of manipulating protein levels in the embryo. Morpholinos,...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rosen JN, Sweeney MF, Mably JD. Microinjection of zebrafish embryos to analyze gene function. J Vis Exp. 2009 Mar 9;(25). pii: 1115. doi: 10.3791/1115..

Miz-1 is required to coordinate the expression of TCRbeta and p53 effector genes at the pre-TCR "beta-selection" checkpoint

Authors:
Saba I, Kosan C, Vassen L, Klein-Hitpass L, Möröy T
Citation:
J Immunol. 2011 Sep 15;187(6):2982-92. doi: 10.4049/jimmunol.1101451. Epub 2011 Aug 12. PMID: 21841135
Epub:
Not Epub
Abstract:
Miz-1 is a Broad-complex, Tramtrack and Bric-à-brac/pox virus zinc finger domain (BTB/POZ)-containing protein expressed in...
Link:
https://journals.aai.org/jimmunol/article/187/6/2982/85751/Miz-1-Is-Required-To-Coordinate-the-Expression-of
Citation Extract:
Saba I, Kosan C, Vassen L, Klein-Hitpass L, Möröy T. Miz-1 is required to coordinate the expression of TCRbeta and p53 effector genes at the pre-TCR "beta-selection" checkpoint. J Immunol. 2011 Sep 15;187(6):2982-92. doi: 10.4049/jimmunol.1101451. Epub 2011 Aug 12. PMID: 21841135.

Modulation of Tcf3 repressor complex composition regulates cdx4 expression in zebrafish

Authors:
Ro H, Dawid IB
Citation:
EMBO J. 2011 Jun 10;30(14):2894-907. doi: 10.1038/emboj.2011.184
Epub:
Not Epub
Abstract:
The caudal homeobox (cdx) gene family is critical for specification of caudal body formation and erythropoiesis. In zebrafish,...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ro H, Dawid IB. Modulation of Tcf3 repressor complex composition regulates cdx4 expression in zebrafish. EMBO J. 2011 Jun 10;30(14):2894-907. doi: 10.1038/emboj.2011.184.

Mutations in ISPD cause Walker-Warburg syndrome and defective glycosylation of α-dystroglycan

Authors:
Roscioli T, Kamsteeg EJ, Buysse K, Maystadt I, van Reeuwijk J, van den Elzen C, van Beusekom E, Riemersma M, Pfundt R, Vissers LE, Schraders M, Altunoglu U, Buckley MF, Brunner HG, Grisart B, Zhou H, Veltman JA, Gilissen C, Mancini GM, Delrée P, Willemsen MA, Ramadža DP, Chitayat D, Bennett C, Sheridan E, Peeters EA, Tan-Sindhunata GM, de Die-Smulders CE, Devriendt K, Kayserili H, El-Hashash OA, Stemple DL, Lefeber DJ, Lin YY, van Bokhoven H
Citation:
Nat Genet. 2012 Apr 22. doi: 10.1038/ng.2253. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Walker-Warburg syndrome (WWS) is an autosomal recessive multisystem disorder characterized by complex eye and brain...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Roscioli T, Kamsteeg EJ, Buysse K, Maystadt I, van Reeuwijk J, van den Elzen C, van Beusekom E, Riemersma M, Pfundt R, Vissers LE, Schraders M, Altunoglu U, Buckley MF, Brunner HG, Grisart B, Zhou H, Veltman JA, Gilissen C, Mancini GM, Delrée P, Willemsen MA, Ramadža DP, Chitayat D, Bennett C, Sheridan E, Peeters EA, Tan-Sindhunata GM, de Die-Smulders CE, Devriendt K, Kayserili H, El-Hashash OA, Stemple DL, Lefeber DJ, Lin YY, van Bokhoven H. Mutations in ISPD cause Walker-Warburg syndrome and defective glycosylation of α-dystroglycan. Nat Genet. 2012 Apr 22. doi: 10.1038/ng.2253. [Epub ahead of print].

Mutations in lectin complement pathway genes COLEC11 and MASP1 cause 3MC syndrome

Authors:
Rooryck C, Diaz-Font A, Osborn DP, Chabchoub E, Hernandez-Hernandez V, Shamseldin H, Kenny J, Waters A, Jenkins D, Kaissi AA, Leal GF, Dallapiccola B, Carnevale F, Bitner-Glindzicz M, Lees M, Hennekam R, Stanier P, Burns AJ, Peeters H, Alkuraya FS, Beales
Citation:
Nat Genet. 2011 Jan 23. [Epub ahead of print]
Epub:
Not Epub
Abstract:
3MC syndrome has been proposed as a unifying term encompassing the overlapping Carnevale, Mingarelli, Malpuech and Michels...
Organism or Cell Type:
zebrafish
Citation Extract:
Rooryck C, Diaz-Font A, Osborn DP, Chabchoub E, Hernandez-Hernandez V, Shamseldin H, Kenny J, Waters A, Jenkins D, Kaissi AA, Leal GF, Dallapiccola B, Carnevale F, Bitner-Glindzicz M, Lees M, Hennekam R, Stanier P, Burns AJ, Peeters H, Alkuraya FS, Beales. Mutations in lectin complement pathway genes COLEC11 and MASP1 cause 3MC syndrome. Nat Genet. 2011 Jan 23. [Epub ahead of print].

Nemo-like kinase (NLK) acts downstream of Notch/Delta signalling to downregulate TCF during mesoderm induction in the sea urchin embryo

Authors:
Röttinger E, Croce J, Lhomond G, Besnardeau L, Gache C, Lepage T
Citation:
Development. 2006 Nov;133(21):4341-53
Epub:
Not Epub
Abstract:
Studies in Caenorhabditis elegans and vertebrates have established that the MAP kinase-related protein NLK counteracts Wnt...
Organism or Cell Type:
Sea urchin, Paracentrotus lividus
Citation Extract:
Röttinger E, Croce J, Lhomond G, Besnardeau L, Gache C, Lepage T. Nemo-like kinase (NLK) acts downstream of Notch/Delta signalling to downregulate TCF during mesoderm induction in the sea urchin embryo. Development. 2006 Nov;133(21):4341-53.

Nodal signalling imposes left-right asymmetry upon neurogenesis in the habenular nuclei

Authors:
Roussigné M, Bianco IH, Wilson SW, Blader P
Citation:
Development. 2009 May;136(9):1549-57
Epub:
Not Epub
Abstract:
The habenulae are evolutionarily conserved bilateral nuclei in the epithalamus that relay input from the forebrain to the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Roussigné M, Bianco IH, Wilson SW, Blader P. Nodal signalling imposes left-right asymmetry upon neurogenesis in the habenular nuclei. Development. 2009 May;136(9):1549-57.

p53 activation by knockdown technologies

Authors:
Robu ME, Larson JD, Nasevicius A, Beiraghi S, Brenner C, Farber SA, Ekker SC
Citation:
PLoS Genet. 2007 May 25;3(5):e78. Epub 2007 Apr 10
Epub:
Not Epub
Abstract:
Morpholino phosphorodiamidate antisense oligonucleotides (MOs) and short interfering RNAs (siRNAs) are commonly used platforms...
Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1877875/
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Robu ME, Larson JD, Nasevicius A, Beiraghi S, Brenner C, Farber SA, Ekker SC. p53 activation by knockdown technologies. PLoS Genet. 2007 May 25;3(5):e78. Epub 2007 Apr 10.

Pages