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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

A Key Role for Poly(ADP-Ribose) Polymerase 3 in Ectodermal Specification and Neural Crest Development

Authors:
Rouleau M, Saxena V, Rodrigue A, Paquet ER, Gagnon A, Hendzel MJ, Masson J-Y, Ekker M, Poirier GG
Citation:
PLoS ONE. 2011;6(1):e15834. doi:10.1371/journal.pone.0015834
Epub:
Not Epub
Abstract:
Background The PARP family member poly(ADP-ribose) polymerase 3 (PARP3) is structurally related to the well characterized PARP1...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rouleau M, Saxena V, Rodrigue A, Paquet ER, Gagnon A, Hendzel MJ, Masson J-Y, Ekker M, Poirier GG. A Key Role for Poly(ADP-Ribose) Polymerase 3 in Ectodermal Specification and Neural Crest Development. PLoS ONE. 2011;6(1):e15834. doi:10.1371/journal.pone.0015834.

A Myc-Slug (Snail2)/Twist regulatory circuit directs vascular development

Authors:
Rodrigues CO, Nerlick ST, White EL, Cleveland JL, King ML
Citation:
Development. 2008 Jun;135(11):1903-11
Epub:
Not Epub
Abstract:
Myc-deficient mice fail to develop normal vascular networks and Myc-deficient embryonic stem cells fail to provoke a tumor...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Rodrigues CO, Nerlick ST, White EL, Cleveland JL, King ML. A Myc-Slug (Snail2)/Twist regulatory circuit directs vascular development. Development. 2008 Jun;135(11):1903-11.

A Xenopus tribbles orthologue is required for the progression of mitosis and for development of the nervous system

Authors:
Saka Y, Smith JC
Citation:
Dev Biol. 2004 Sep 15;273(2):210-25.
Epub:
Not Epub
Abstract:
The product of the Drosophila gene tribbles inhibits cell division in the ventral furrow of the embryo and thereby allows the...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Saka Y, Smith JC. A Xenopus tribbles orthologue is required for the progression of mitosis and for development of the nervous system. Dev Biol. 2004 Sep 15;273(2):210-25..

An early Fgf signal required for gene expression in the zebrafish hindbrain primordium

Authors:
Roy NM, Sagerstrom CG
Citation:
Brain Res Dev Brain Res. 2004 Jan 31;148(1):27-42
Epub:
Not Epub
Abstract:
We have explored the role of fibroblast growth factor (Fgf) signaling in regulating gene expression in the early zebrafish...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Roy NM, Sagerstrom CG. An early Fgf signal required for gene expression in the zebrafish hindbrain primordium. Brain Res Dev Brain Res. 2004 Jan 31;148(1):27-42.

Analysis of Dll4 regulation reveals a combinatorial role for Sox and Notch in arterial development

Authors:
Sacilotto N, Monteiro R, Fritzsche M, Becker PW, Sanchez-del-Campo L, Liu K, Pinheiro P, Ratnayaka I, Davies B, Goding CR, Patient R, Bou-Gharios G, De Val S
Citation:
PNAS. 2013;[Epub ahead of print] doi:10.1073/pnas.1300805110
Epub:
Not Epub
Abstract:
The mechanisms by which arterial fate is established and maintained are not clearly understood. Although a number of signaling...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sacilotto N, Monteiro R, Fritzsche M, Becker PW, Sanchez-del-Campo L, Liu K, Pinheiro P, Ratnayaka I, Davies B, Goding CR, Patient R, Bou-Gharios G, De Val S. Analysis of Dll4 regulation reveals a combinatorial role for Sox and Notch in arterial development. PNAS. 2013;[Epub ahead of print] doi:10.1073/pnas.1300805110 .

Antisense oligonucleotide treatment for a pseudoexon-generating mutation in the NPC1 gene causing Niemann-Pick type C disease

Authors:
Rodríguez-Pascau L, Coll MJ, Vilageliu L, Grinberg D
Citation:
Hum Mutat. 2009 Aug 30. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Niemann-Pick type C disease is an autosomal recessive disorder caused by mutations in either the NPC1 or NPC2 gene. While most...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: human fibroblasts
Citation Extract:
Rodríguez-Pascau L, Coll MJ, Vilageliu L, Grinberg D. Antisense oligonucleotide treatment for a pseudoexon-generating mutation in the NPC1 gene causing Niemann-Pick type C disease. Hum Mutat. 2009 Aug 30. [Epub ahead of print].

Antisense PMO Found in Dystrophic Dog Model Was Effective in Cells from Exon 7-Deleted DMD Patient

Authors:
Saito T, Nakamura A, Aoki Y, Yokota T, Okada T, Osawa M, Takeda S
Citation:
PLoS ONE. 2010 Aug;5(8):e12239. doi:10.1371/journal.pone.0012239
Epub:
Not Epub
Abstract:
Background Antisense oligonucleotide-induced exon skipping is a promising approach for treatment of Duchenne muscular dystrophy...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC2923599/
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: dog and human
Citation Extract:
Saito T, Nakamura A, Aoki Y, Yokota T, Okada T, Osawa M, Takeda S. Antisense PMO Found in Dystrophic Dog Model Was Effective in Cells from Exon 7-Deleted DMD Patient. PLoS ONE. 2010 Aug;5(8):e12239. doi:10.1371/journal.pone.0012239.

Asymmetric Involution of the Myocardial Field Drives Heart Tube Formation in Zebrafish

Authors:
Rohr S, Otten C, Abdelilah-Seyfried S
Citation:
Circ Res. 2008 Feb 1;102(2):e12-9. Epub 2008 Jan 17.
Epub:
Not Epub
Abstract:
Many vertebrate organs are derived from monolayered epithelia that undergo morphogenesis to acquire their shape. Whereas...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rohr S, Otten C, Abdelilah-Seyfried S. Asymmetric Involution of the Myocardial Field Drives Heart Tube Formation in Zebrafish. Circ Res. 2008 Feb 1;102(2):e12-9. Epub 2008 Jan 17..

BMPs and Chordin regulate patterning of the directive axis in a sea anemone

Authors:
Saina M, Genikhovich G, Renfer E, Technau U
Citation:
Proc Natl Acad Sci U S A. 2009 Oct 15. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The TGF-beta molecules Dpp/BMP2/4/7 and their antagonist Sog/Chd play a conserved role in establishing the dorso-ventral (DV)...
Organism or Cell Type:
Nematostella vectensis (cnidarian)
Citation Extract:
Saina M, Genikhovich G, Renfer E, Technau U. BMPs and Chordin regulate patterning of the directive axis in a sea anemone. Proc Natl Acad Sci U S A. 2009 Oct 15. [Epub ahead of print].

CaMK-II Activation is Essential for Zebrafish Inner Ear Development and Acts through Delta-Notch Signaling

Authors:
Rothschild SC, Lahvic J, Francescatto L, McLeod JJ, Burgess SM, Tombes RM
Citation:
Dev Biol. 2013 Jun 6. doi:pii: S0012-1606(13)00310-2. 10.1016/j.ydbio.2013.05.028. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Zebrafish inner ear development is characterized by the crystallization of otoliths onto immotile kinocilia that protrude from...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rothschild SC, Lahvic J, Francescatto L, McLeod JJ, Burgess SM, Tombes RM. CaMK-II Activation is Essential for Zebrafish Inner Ear Development and Acts through Delta-Notch Signaling. Dev Biol. 2013 Jun 6. doi:pii: S0012-1606(13)00310-2. 10.1016/j.ydbio.2013.05.028. [Epub ahead of print].

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