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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

The zebrafish runzel muscular dystrophy is linked to the titin gene

Authors:
Steffen LS, Guyon JR, Vogel ED, Howell MH, Zhou Y, Weber GJ, Zon LI, Kunkel LM
Citation:
Dev Biol. 2007 Sep 15;309(2):180-92. Epub 2007 Jun 23.
Epub:
Not Epub
Abstract:
Titin (also called connectin) acts as a scaffold for signaling proteins in muscle and is responsible for establishing and...
Organism or Cell Type:
zebrafish
Citation Extract:
Steffen LS, Guyon JR, Vogel ED, Howell MH, Zhou Y, Weber GJ, Zon LI, Kunkel LM. The zebrafish runzel muscular dystrophy is linked to the titin gene. Dev Biol. 2007 Sep 15;309(2):180-92. Epub 2007 Jun 23..

Transcriptome analysis of Traf6 function in the innate immune response of zebrafish embryos

Authors:
Stockhammer OW, Rauwerda H, Wittink FR, Breit TM, Meijer AH, Spaink HP
Citation:
Mol Immunol. 2010 Sep 17. [Epub ahead of print]
Epub:
Not Epub
Abstract:
TRAF6 is a key player at the cross-roads of development and immunity. The analysis of its in vivo molecular function is a great...
Organism or Cell Type:
zebrafish
Citation Extract:
Stockhammer OW, Rauwerda H, Wittink FR, Breit TM, Meijer AH, Spaink HP. Transcriptome analysis of Traf6 function in the innate immune response of zebrafish embryos. Mol Immunol. 2010 Sep 17. [Epub ahead of print].

Transcriptome profiling and functional analyses of the zebrafish embryonic innate immune response to Salmonella infection

Authors:
Stockhammer OW, Zakrzewska A, Hegedûs Z, Spaink HP, Meijer AH
Citation:
J Immunol. 2009 May 1;182(9):5641-53
Epub:
Not Epub
Abstract:
Due to the clear separation of innate immunity from adaptive responses, the externally developing zebrafish embryo represents a...
Organism or Cell Type:
zebrafish
Citation Extract:
Stockhammer OW, Zakrzewska A, Hegedûs Z, Spaink HP, Meijer AH. Transcriptome profiling and functional analyses of the zebrafish embryonic innate immune response to Salmonella infection. J Immunol. 2009 May 1;182(9):5641-53.

Treatment of AG129 mice with antisense morpholino oligomers increases survival time following challenge with dengue 2 virus

Authors:
Stein DA, Huang CY, Silengo S, Amantana A, Crumley S, Blouch RE, Iversen PL, Kinney RM
Citation:
J Antimicrob Chemother. 2008 Sep;62(3):555-65. Epub 2008 Jun 19
Epub:
Not Epub
Abstract:
Objectives To determine the antiviral activity of phosphorodiamidate morpholino oligomers (PMO) and peptide-conjugated PMO (...
Link:
http://jac.oxfordjournals.org/content/62/3/555.long
Delivery Method:
i.p. injection
Organism or Cell Type:
mice
Citation Extract:
Stein DA, Huang CY, Silengo S, Amantana A, Crumley S, Blouch RE, Iversen PL, Kinney RM. Treatment of AG129 mice with antisense morpholino oligomers increases survival time following challenge with dengue 2 virus. J Antimicrob Chemother. 2008 Sep;62(3):555-65. Epub 2008 Jun 19.

Uncharged Nucleic Acid Analogs for Therapeutic and Diagnostic Applications: Oligomers Assembled from Ribose-Derived Subunits

Authors:
Summerton J
Citation:
In Advances in Applied Biotechnology Series, Volume 2, Discoveries in Antisense Nucleic Acids. C. Brakel, Ed. 1989 Portfolio Publishing Company, The Woodlands. 71-
Epub:
Not Epub
Abstract:
We have devised a class of uncharged sequence-specific nucleic asid-binding oligomers, Neu-Genes(TM) (short for neutral genes...
Citation Extract:
Summerton J. Uncharged Nucleic Acid Analogs for Therapeutic and Diagnostic Applications: Oligomers Assembled from Ribose-Derived Subunits. In Advances in Applied Biotechnology Series, Volume 2, Discoveries in Antisense Nucleic Acids. C. Brakel, Ed. 1989 Portfolio Publishing Company, The Woodlands. 71-.

Uncharged stereoregular nucleic acid analogs: 1. Synthesis of a cytosine-containing oligomer with carbamate internucleoside linkages

Authors:
Stirchak EP, Summerton JE, Weller DD
Citation:
J. Org. Chem. 1987 52:4202-06
Epub:
Not Epub
Abstract:
No Abstract Available This paper describes synthesis of an oligo which was an intermediate step along the path of the...
Delivery Method:
not applicable
Organism or Cell Type:
not applicable
Citation Extract:
Stirchak EP, Summerton JE, Weller DD. Uncharged stereoregular nucleic acid analogs: 1. Synthesis of a cytosine-containing oligomer with carbamate internucleoside linkages. J. Org. Chem. 1987 52:4202-06.

Uncharged stereoregular nucleic acid analogs: 2. Morpholino nucleoside oligomers with carbamate internucleoside linkages

Authors:
Stirchak EP, Summerton JE, Weller DD
Citation:
Nucleic Acids Res. 1989 Aug 11;17(15):6129-41
Epub:
Not Epub
Abstract:
A novel oligonucleotide analog has been prepared from ribonucleoside derived morpholine subunits linked by carbamate groups....
Delivery Method:
not applicable
Organism or Cell Type:
not applicable
Citation Extract:
Stirchak EP, Summerton JE, Weller DD. Uncharged stereoregular nucleic acid analogs: 2. Morpholino nucleoside oligomers with carbamate internucleoside linkages. Nucleic Acids Res. 1989 Aug 11;17(15):6129-41.

Unwinding of nucleic acids by HCV NS3 helicase is sensitive to the structure of the duplex

Authors:
Tackett AJ, Wei L, Cameron CE, Raney KD
Citation:
Nucleic Acids Res 2001 Jan 15;29(2):565-572
Epub:
Not Epub
Abstract:
Hepatitis C virus (HCV) helicase, non-structural protein 3 (NS3), is proposed to aid in HCV genome replication and is...
Citation Extract:
Tackett AJ, Wei L, Cameron CE, Raney KD. Unwinding of nucleic acids by HCV NS3 helicase is sensitive to the structure of the duplex. Nucleic Acids Res 2001 Jan 15;29(2):565-572.

Use of target protector morpholinos to analyze the physiological roles of specific miRNA-mRNA pairs in vivo

Authors:
Staton AA, Giraldez AJ
Citation:
Nat Protoc. 2011 Dec 1;6(12):2035-2049. doi: 10.1038/nprot.2011.423
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) regulate gene expression by pairing with complementary sequences in the 3' untranslated regions (UTRs)...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Staton AA, Giraldez AJ. Use of target protector morpholinos to analyze the physiological roles of specific miRNA-mRNA pairs in vivo. Nat Protoc. 2011 Dec 1;6(12):2035-2049. doi: 10.1038/nprot.2011.423.

Validation of novel secondary dystroglycanopathy genes using biochemical, cellular and zebrafish studies

Authors:
Stevens E, Carss K, Cirak S, Torelli S, Foley AR, Sewry C, Topaloglu H, Haliloglu G, Stemple D, Hurles M, Lin YY, Muntoni F
Citation:
Neuromusc Disord. 2012;22(9):812
Epub:
Not Epub
Abstract:
Mutations in several known genes such as LARGE, POMT1, POMT2, POMGnT1, FKRP, FKTN, DPM2, DPM3, and DOLK are capable of causing...
Organism or Cell Type:
zebrafish
Citation Extract:
Stevens E, Carss K, Cirak S, Torelli S, Foley AR, Sewry C, Topaloglu H, Haliloglu G, Stemple D, Hurles M, Lin YY, Muntoni F. Validation of novel secondary dystroglycanopathy genes using biochemical, cellular and zebrafish studies. Neuromusc Disord. 2012;22(9):812.

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