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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Physiological and Molecular Characterization of Connexin Hemichannels in Zebrafish Retinal Horizontal Cells

Authors:
Sun Z, Risner ML, van Asselt JB, Zhang DQ, Kamermans M, McMahon DG
Citation:
J Neurophysiol. 2012 Feb 22. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Connexin channels mediate electrical synaptic transmission when assembled as cell-to-cell pores at gap junctions and can...
Delivery Method:
Injection then electroporation in vivo
Organism or Cell Type:
zebrafish
Citation Extract:
Sun Z, Risner ML, van Asselt JB, Zhang DQ, Kamermans M, McMahon DG. Physiological and Molecular Characterization of Connexin Hemichannels in Zebrafish Retinal Horizontal Cells. J Neurophysiol. 2012 Feb 22. [Epub ahead of print].

Plasticity of photoreceptor-generating retinal progenitors revealed by prolonged retinoic acid exposure

Authors:
Stevens CB, Cameron DA, Stenkamp DL
Citation:
BMC Dev Biol. 2011;11:51 doi:10.1186/1471-213X-11-51
Epub:
Not Epub
Abstract:
BACKGROUND Retinoic acid (RA) is important for vertebrate eye morphogenesis and is a regulator of photoreceptor development in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Stevens CB, Cameron DA, Stenkamp DL. Plasticity of photoreceptor-generating retinal progenitors revealed by prolonged retinoic acid exposure. BMC Dev Biol. 2011;11:51 doi:10.1186/1471-213X-11-51.

Regulation and function of foxe3 during early zebrafish development

Authors:
Swindell EC, Zilinski CA, Hashimoto R, Shah R, Lane ME, Jamrich M
Citation:
Genesis. 2008 Mar;46(3):177-83.
Epub:
Not Epub
Abstract:
In this article, we investigate the expression, regulation, and function of the zebrafish forkhead gene foxe3. In wild type...
Organism or Cell Type:
zebrafish
Citation Extract:
Swindell EC, Zilinski CA, Hashimoto R, Shah R, Lane ME, Jamrich M. Regulation and function of foxe3 during early zebrafish development. Genesis. 2008 Mar;46(3):177-83..

Regulation of Emx2 expression by antisense transcripts in murine cortico-cerebral precursors

Authors:
Spigoni G, Gedressi C, Mallamaci A
Citation:
PLoS One. 2010 Jan 11;5(1):e8658
Epub:
Not Epub
Abstract:
BACKGROUND: Emx2 encodes for a transcription factor expressed in the embryonic intermediate mesoderm and central nervous system...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: NIH-3T3 cells
Citation Extract:
Spigoni G, Gedressi C, Mallamaci A. Regulation of Emx2 expression by antisense transcripts in murine cortico-cerebral precursors. PLoS One. 2010 Jan 11;5(1):e8658.

Regulation of isthmic Fgf8 signal by sprouty2

Authors:
Suzuki-Hirano A, Sato T, Nakamura H
Citation:
Development. 2005 Jan;132(2):257-65. Epub 2004 Dec 8
Epub:
Not Epub
Abstract:
Fgf8 functions as an organizer at the mes/metencephalic boundary (isthmus). We showed that a strong Fgf8 signal activates the...
Delivery Method:
Electroporation
Organism or Cell Type:
chick embryo
Citation Extract:
Suzuki-Hirano A, Sato T, Nakamura H. Regulation of isthmic Fgf8 signal by sprouty2. Development. 2005 Jan;132(2):257-65. Epub 2004 Dec 8.

Repair of a Splicing Defect in Erythroid Cells from Patients with beta-Thalassemia/HbE Disorder

Authors:
Suwanmanee T, Sierakowska H, Fucharoen S, Kole R
Citation:
Mol Ther. 2002 Dec;6(6):718-26.
Epub:
Not Epub
Abstract:
A HeLa cell line stably expressing the human beta-globin gene carrying thalassemic mutations beta(E)/IVS1-6 served as a...
Delivery Method:
scrape loading and syringe loading
Organism or Cell Type:
cell culture: C2C12 cells
Citation Extract:
Suwanmanee T, Sierakowska H, Fucharoen S, Kole R. Repair of a Splicing Defect in Erythroid Cells from Patients with beta-Thalassemia/HbE Disorder. Mol Ther. 2002 Dec;6(6):718-26..

Restoration of Human beta-Globin Gene Expression in Murine and Human IVS2-654 Thalassemic Erythroid Cells by Free Uptake of Antisense Oligonucleotides

Authors:
Suwanmanee T, Sierakowska H, Lacerra G, Svasti S, Kirby S, Walsh CE, Fucharoen S, Kole R
Citation:
Mol Pharmacol. 2002 Sep;62(3):545-53.
Epub:
Not Epub
Abstract:
Correct human beta-globin mRNA has been restored in erythroid cells from transgenic mice carrying the human gene with beta-...
Delivery Method:
syringe loading and free uptake
Organism or Cell Type:
cell culture: Hela and human erythroid precursor cells
Citation Extract:
Suwanmanee T, Sierakowska H, Lacerra G, Svasti S, Kirby S, Walsh CE, Fucharoen S, Kole R. Restoration of Human beta-Globin Gene Expression in Murine and Human IVS2-654 Thalassemic Erythroid Cells by Free Uptake of Antisense Oligonucleotides. Mol Pharmacol. 2002 Sep;62(3):545-53..

Retinoids signal directly to zebrafish endoderm to specify insulin-expressing beta-cells

Authors:
Stafford D, White RJ, Kinkel MD, Linville A, Schilling TF, Prince VE
Citation:
Development. 2006 Mar;133(5):949-56. Epub 2006 Feb 1
Epub:
Not Epub
Abstract:
During vertebrate development, the endodermal germ layer becomes regionalized along its anteroposterior axis to give rise to a...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Stafford D, White RJ, Kinkel MD, Linville A, Schilling TF, Prince VE. Retinoids signal directly to zebrafish endoderm to specify insulin-expressing beta-cells. Development. 2006 Mar;133(5):949-56. Epub 2006 Feb 1.

Retinol dehydrogenase 10 is a feedback regulator of retinoic acid signalling during axis formation and patterning of the central nervous system

Authors:
Strate I, Min TH, Iliev D, Pera EM
Citation:
Development. 2009 Feb;136(3):461-72
Epub:
Not Epub
Abstract:
Retinoic acid (RA) is an important morphogen that regulates many biological processes, including the development of the central...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Strate I, Min TH, Iliev D, Pera EM. Retinol dehydrogenase 10 is a feedback regulator of retinoic acid signalling during axis formation and patterning of the central nervous system. Development. 2009 Feb;136(3):461-72.

RNA repair restores hemoglobin expression in IVS2-654 thalassemic mice

Authors:
Svasti S, Suwanmanee T, Fucharoen S, Moulton HM, Nelson MH, Maeda N, Smithies O, Kole R
Citation:
Proc Natl Acad Sci U S A. 2009 Jan 27;106(4):1205-10. Epub 2009 Jan 21
Epub:
Not Epub
Abstract:
Repair of beta-globin pre-mRNA rendered defective by a thalassemia-causing splicing mutation, IVS2-654, in intron 2 of the...
Delivery Method:
peptide-coupled
Organism or Cell Type:
mouse: IVS2-654
Citation Extract:
Svasti S, Suwanmanee T, Fucharoen S, Moulton HM, Nelson MH, Maeda N, Smithies O, Kole R. RNA repair restores hemoglobin expression in IVS2-654 thalassemic mice. Proc Natl Acad Sci U S A. 2009 Jan 27;106(4):1205-10. Epub 2009 Jan 21.

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